Abstract: Implants can be used as flow diverters for treating aneurysms. Implants can include a stabilizing frame for anchoring the implant and an occluding element for diverting blood flow from the aneurysm neck. The stabilizing frame can have two parts, the first part sized to anchor within the sac of the aneurysm and the exterior part sized to anchor against a region of the blood vessel wall adjacent the aneurysm neck. The occluding element can be attached to the interior frame and positioned to occlude the aneurysm neck. The implant can have a central node that can be positioned near the center of the aneurysm neck at which the interior frame is attached to the exterior frame and from which the interior frame and the exterior frame extend.

Abstract: The invention relates to a fastening device for implant device, the fastening device comprising at least two fastening sections, where a first fastening section is arranged with a through hole, a second fastening section is arranged with a protruding part, and where said protruding part is in place in said through hole in a fastening device locking state, where the protruding part on the second fastening section is arranged with a through channel having an inlet and an outlet, said through channel being arranged to receive an implant device feed member, said inlet and outlet being accessible from the exterior of the fastening device in said fastening device locking state, wherein the first fastening section is securely locked to the second fastening section when, in said fastening device locking state, said implant device feed member is in place in the through channel and protrudes from both the inlet and the outlet of said through channel.

Abstract: A system includes a platform configured for insertion into a user's nostril and a catheter. The platform includes a board having first and second major surfaces and a support extending from the board. The support includes an aperture therethrough. The catheter includes an inflatable tube and a lumen having first and second ends, the first end connected to the tube and the second end connected to a pressurized fluid source for inflating the tube. The tube is configured for insertion through the aperture. A method includes inserting a platform into a user's nostril, inserting a catheter through an aperture of the platform, and inflating a tube of the catheter. Inflating the tube is accomplished by introducing a pressurized fluid through a lumen of the catheter, to thereby cause the tube to conform to a passage of the user's nasal or pharyngeal region.

Abstract: An apparatus includes a shaft, an expandable dilation member, and a bulbous tip. The shaft has a first outer cross-sectional dimension. The dilation member is positioned proximal to the distal end of the shaft. The dilation member is operable to transition between a non-expanded configuration and an expanded configuration. The dilation member is sized to pass through a passageway associated with drainage of a paranasal sinus or a Eustachian tube when the dilation member is in the non-expanded configuration. The bulbous tip is positioned at the distal end of the shaft. The bulbous tip is distal to the dilation member. The bulbous tip has a second outer cross-sectional dimension. The second outer cross-sectional dimension is larger than the first outer cross-sectional dimension. The bulbous tip is removably secured to the distal end of the shaft.

Abstract: A medical device system may include a delivery device including an outer sheath and an inner shaft having a coupler fixed to a distal end of the inner shaft, and a replacement heart valve implant releasably attached to the coupler, the replacement heart valve implant including an expandable anchor member and a plurality of locking mechanisms configured to engage with the coupler. The delivery device may include a plurality of collars configured to secure the coupler to the plurality of locking mechanisms. The delivery device may include a stop element configured to selectively prevent disengagement of the plurality of collars from the plurality of locking mechanisms.

Abstract: A handle assembly of a surgical instrument includes a housing, a trigger pivotably coupled to the housing, a drive bar disposed within the housing and operably coupled to the trigger such that pivoting of the trigger translates the drive bar, and a bilateral spring disposed within the housing and operably coupled to at least one of the trigger or the drive bar. The trigger is movable relative to the housing between first, second, and third positions wherein the first position is disposed between the second and third positions. The bilateral spring includes a compression spring configured to compress upon movement of the trigger in a first direction from the first position towards the second position to establish a first bias, and to compress upon movement of the trigger in a second, opposite direction from the first position towards the third position to establish a second bias.

Abstract: A needle reload device includes a loading assembly including a needle holder pulley and a needle release arm. The needle holder pulley includes a base including first and second portions configured to receive a needle. The needle release arm is transitionable between an engaged state, in which the needle release arm engages the needle holder pulley to inhibit rotation of the needle holder pulley, and a disengaged state, in which the needle release arm is disengaged from the needle holder pulley such that the needle holder pulley is rotatable. When the needle release arm is in the engaged state, the first portion of the needle holder pulley is positioned between jaws of a stitching device, and when the needle release arm is in the disengage state, the second portion of the base of the needle holder pulley is positioned between the jaws.

Abstract: A fabric or mesh construct, and process for making same, which allows for early wound stability and then transitions to a more compliant state exhibiting a substantially constant macro-porous pore structure through the life of the implant to promote good tissue incorporation without bridging.

Abstract: A tissue displacing and fastening device is provided for manipulating and fastening tissue together. The device includes a tissue displacing elements, which displaces tissue. A fold is formed from the displaced tissue and the tissue is fastened together to secure the fold.

Abstract: This invention relates to the design and function of a compressible valve replacement prosthesis which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

Abstract: A device can be introduced into the right atrium of a subject's heart by introducing the distal end of a hollow, straight, and stiff shaft into the subject's right internal jugular vein, and advancing the distal end of the shaft into the right atrium via the superior vena cava. The position of the distal end of the shaft is adjusted by manipulating a handle affixed to a portion of the shaft that remains outside the subject's body. The handle can be used to rotate the shaft about its longitudinal axis, rotate the shaft about an anterior-posterior axis, rotate the shaft about a medial-lateral axis, and/or advance the shaft in the caudal direction. A device is advanced through the interior of the shaft until the device extends beyond the distal end of the shaft and into the right atrium.

Abstract: An aneurysm treatment system that includes an embolic implant, a delivery system, and an introducer sheath that are collectively designed so that the combination of the introducer sheath and the delivery system can be used as a deployment apparatus for the embolic implant. The delivery system can have a pull wire, a delivery tube, and an interference feature attached to the pull wire and positioned near a proximal end of the delivery tube. Rather than being discarded, the introducer sheath can be moved proximally over the delivery tube until it engages the interference feature. To deploy the implant, the introducer sheath can be pressed against the interference feature, causing the interference feature to move proximally in relation to the delivery tube, thereby proximally pulling the pull wire to which the interference feature is attached and deploying the implant.

Abstract: Medical systems, devices and methods are provided for engaging tissue, e.g. for clipping tissue, closing a perforation or performing hemostasis. Generally, the medical system including a housing, first and second jaws rotatable relative to the housing, a driver, and an elongate drive wire. The elongate drive wire may be disconnected from the driver, first and second jaws, and the housing, which are left in vivo engaged with the tissue.

Abstract: A prosthetic heart valve delivery system can include a catheter portion having a sheath that can cover and uncover the prosthetic heart valve mounted on an inner shaft, a handle having a sheath actuator operatively coupled to a proximal portion of the sheath, the inner shaft extending through the handle, and a shaft retractor releasably coupled to a proximal portion of the handle and fixedly coupled to a proximal portion of the inner shaft. A sheath actuator can move the sheath axially relative to the inner shaft when the shaft retractor is coupled to the handle, and a proximal movement of the sheath relative to the inner shaft can cause the sheath to uncover the prosthetic heart valve. The shaft retractor can be operable to retract the inner shaft and the nosecone proximally relative to the sheath when the shaft retractor is released from the handle.

Abstract: The technical problem to be solved by the present invention is to design a cosmetic surgical method for presenting a deeper or longer philtrum at the lip by adjusting the muscle flaps at the lips and nose. The theoretical basis of this surgical method is a “theory of labionasal muscle tension thread group” summarized from a series of studies with respect to anatomy, biomechanics and clinical surgical verification. According to this theory, the labionasal muscle tension structure is reconstructed by surgical adjustment of the position and direction of the muscle flaps, so as to produce an effect of changing the profile of the “philtrum” and to improve or remodel the “philtrum” as an aesthetic labial structure.

Abstract: A surgical device is provided and includes a handle housing, an endoscopic assembly, and a follower assembly. The endoscopic assembly extends distally from the handle housing and includes an inner tube defining a longitudinal axis. The inner tube includes a distal portion defining a pair of opposed tines. The endoscopic assembly is configured to support a plurality of anchors at least partially therein. The follower assembly is disposed at least partially within the inner tube at a location proximal of the plurality of anchors, and includes a head and a shaft. A portion of the head is disposed between the pair of opposed tines. Actuation of the endoscopic surgical device causes rotation of the inner tube about the longitudinal axis relative to the handle housing, and causes distal advancement of the follower assembly relative to the inner tube.

Abstract: Apparatus is provided for use with a delivery catheter, including a primary stent-graft and a flared endovascular stent-graft, which is configured to initially be positioned in the delivery catheter in a radially-compressed state, and to assume a radially-expanded state upon being deployed from the delivery catheter.

Abstract: A uterine manipulator includes a handle assembly and a shaft extending distally from the handle assembly. An end effector assembly is disposed at a distal end portion of the shaft and includes a cervical cup and a distal tip extending distally from the cervical cup. A specimen containment system is supported on the shaft between the handle assembly and the end effector assembly. The specimen containment system includes a sleeve having a proximal end portion and a distal end portion, and a specimen containment bag having a first end portion and a second end portion. The specimen containment bag is supported within the sleeve and is movable from an initial position, wherein the specimen containment bag is disposed within the sleeve, to a deployed position, wherein the specimen containment bag is deployed from the sleeve.

Abstract: A device includes a medusa wire group with at least three separate wires slidably received in a vascular catheter. The multiple wires of the medusa wire group maximize the chances of at least one wire entering a target branch vessel during an attempt to achieve access. Entry into the branch vessel may then be gained by advancing the vascular catheter over the at least one wire that successfully entered the branch passageway.

Abstract: A specimen retrieval device includes a tubular body defining a longitudinal bore, an inner shaft slidably disposed within the longitudinal bore of the tubular body, and a specimen bag affixed to a support mechanism at the distal portion of the inner shaft. In embodiments, the specimen bag has an opening capable of being closed by linkage assembly after placement of tissue therein, but prior to removal of the device from the body.