Abstract: Various techniques are provided to implement, operate, and manufacture a chemical detection device. In one embodiment, a device includes a flow path comprising an analyte reporter configured to receive samples passed by the flow path. The device also includes an excitation source configured generate a response from the analyte reporter. The device also includes a detector configured to receive the response from the analyte reporter to determine whether the samples comprise a material of interest. The device also includes a support structure configured to position the flow path relative to the excitation source and the detector, wherein the support structure comprises a carbon filled polymer material. Additional devices, systems, and methods are also provided.

Abstract: An optical arrangement has a light source, which emits a light beam along a first optical axis. A first reflector is provided, and a second reflector reflects light reflected by the first reflector. The first reflector has a transverse offset from the first optical axis to reflect light along a second optical axis which has a parallel offset of two times the transverse offset of the first optical axis. The second reflector reflects the light beam back to the first reflector along a third optical axis having a parallel offset with a fixed amount in a fixed transverse direction in relation to the second optical axis. The light beam is reflected by the first reflector along a fourth optical axis which has a parallel offset in relation to the first optical axis with a fixed amount counter to the fixed transverse direction.

Abstract: Described are methods and systems using optical fiber interferometry to sense interference causing events in a region of interest and differentiate between a strain event and a thermal event. Other methods and systems relate to the use of optical fiber interferometry for determining temperature offset in a region of interest and using the determined temperature offset for determining temperature in the region of interest.

Abstract: A spectrometry device includes a controller that: causes first irradiated light and second irradiated light to be irradiated from a first light emitter and a second light emitter at mutually different timings; stores information relating to a first light reception signal and information relating to a second light reception signal in a storage at mutually different timings, in synchronization with irradiation timings of the first irradiation light and the second irradiation light; acquires information relating to a first optical spectrum based on the information relating to the first light reception signal stored in the storage during a first time period; and acquires information relating to a second optical spectrum based on the information relating to the second reception signal stored in the storage during a second time period.

Abstract: A sensor device removably attachable to a drug delivery device includes a sensing arrangement arranged within the sensor device and circuitry configured to process signals provided by the sensing arrangement. The sensing arrangement is configured such that, when the sensor device is attached to the drug delivery device, the sensing arrangement is operable to read encoded information present on a rotatable component internal to the drug delivery device and that is able to be sensed through a window or aperture of the drug delivery device, and is operable to sense through the window or aperture at least a part of a drive mechanism of the drug delivery device. The circuitry is configured to determine information relating to a set dose, and to determine information relating to whether the drug delivery device is in a dose setting mode or whether the device is in a dose delivery mode.

Abstract: An optical assembly is disclosed including two laterally variable bandpass optical filters stacked at a fixed distance from each other, so that the upstream filter functions as a spatial filter for the downstream filter. The lateral displacement may cause a suppression of the oblique beam when transmission passbands at impinging locations of the oblique beam onto the upstream and downstream filters do not overlap. A photodetector array may be disposed downstream of the downstream filter. The optical assembly may be coupled via a variety of optical conduits or optical fibers for spectroscopic measurements of a flowing sample.

Abstract: The appearance inspection device inspects an appearance of a crimp terminal by capturing an image of the crimp terminal with a camera while applying illumination light onto the crimp terminal. The device includes an illumination unit for applying illumination light onto a crimp terminal and cameras that capture an image of the crimp terminal. A planar gradation light source having brightness that gradually changes in a predetermined direction from one side on an illumination surface toward another side is provided as the illumination unit. The cameras are disposed such that the gradation light source is reflected on an image obtained by the camera capturing the image of the crimp terminal, as a reflected image on a surface of the crimp terminal.

Abstract: A method for the determination of antibiotic susceptibility through stimulated Raman scattering microscopy is disclosed. The method utilizes a imaging apparatus adapted to collect a laser signal through a sample having a bacteria for imaging the metabolism of the sample. The sample can be manipulated with an antibiotic for imaging to determine the susceptibility of a bacteria to the provided antibiotic.

Abstract: A spectrometer and a micro-total analysis system are provided. The spectrometer includes a waveguide structure, a light source, a collimating mirror, a reflection grating, and a light extraction structure. The collimating mirror is configured to convert light, which is emitted from the light source, passes through the waveguide structure, and is incident on the collimating mirror, into collimating light. The reflection grating is configured to allow emergency angles of light of different wavelength ranges among the collimating light incident on the reflection grating to be different, so that the light of different wavelength ranges has an offset in the total reflection propagation process. The light extraction structure is located on the reflection surface of the waveguide structure through which the light of different wavelength ranges passes in the total reflection propagation process, so that the light of different wavelength ranges emits from the light extraction structure.

Abstract: An absorption spectroscopic system is provided with a detector that detects an intensity of light transmitted through a gas, a total pressure sensor that measures a total pressure of the gas, an interference gas partial pressure-absorbance relationship storage unit that stores interference gas partial pressure-absorbance relationship data, an interference gas partial pressure estimation unit that estimates the partial pressure of the interference gas based on the total pressure measured by the total pressure sensor, an interference gas absorbance conversion unit that converts an estimated partial pressure of the interference gas estimated by the interference gas partial pressure estimation unit into an absorbance of the interference gas based on the interference gas partial pressure-absorbance relationship data, and a target gas absorbance calculation unit that calculates an absorbance of the target gas based on output values from the detector and on the absorbance of the interference gas.

Abstract: A wafer-grade LED detection device and a wafer-grade LED detection method are provided. The wafer-grade LED detection device includes a light-generating module for providing a first light beam that passes through an LED wafer to be converted into a second light beam, a light-filtering module adjacent to the LED wafer for receiving the second light beam that passes through the light-filtering module to be converted into a third light beam, and a light-detecting module adjacent to the light-filtering module for receiving and detecting the third light beam. A wavelength range of the second light beam is restricted by the light-filtering module, so that a wavelength range of the third light beam is smaller than the wavelength range of the second light beam. When the third light beam is received by the light-detecting module, the light-detecting module can detect the third light beam for obtaining relevant information.

Abstract: Systems and methods which provide a high-throughput point source light coupling structure implementing a condenser configured according to one or more condenser configuration rules are described. Embodiments of a high-throughput point source light coupling structure utilize a birefringent plate configuration in combination with a condenser and point source to provide a light coupler structure for a birefringent-static-Fourier transform interferometer implementation. According to some examples, the optical axis of a first and second birefringent plate of a birefringent plate configuration are not in the same plane. A condenser of a high-throughput point source light coupling structure of embodiments is provided in a defined (e.g., spaced, relational, etc.) relationship with respect to the point source and/or a camera lens used in capturing an interference pattern generated by the light coupling structure.

Abstract: Systems and methods for measuring the isotope ratio of one or more gaseous oxides produced during combustion of drugs, pharmaceuticals, or medicines aiming to detect counterfeit drugs, pharmaceuticals, or medicines based on comparison of the isotopic composition of the tested drugs, pharmaceuticals, or medicines with the isotopic composition of the authentic products.

Abstract: An apparatus comprising a spectral filter (26) with a variable spectral filter transmission (FT(?)); an event-based imaging sensor (27) configured to produce measurement events (y1, y2, . . . , yn) which correspond to a change in a filter response (Y(t)) that is generated by an observed spectrum (X(?)), and a processor (28) configured to control the filter transmission (FT(?)) of the spectral filter (26) so that it sweeps over wavelength (?) with time (t), and to generate an estimation (X*(?)) of the observed spectrum (X(?)) based on the measurement events (y1, y2, . . . , yn) that correspond to the filter response (Y(t)) and based on the filter transmission (FT(?)).

Abstract: A method for determining crystal phases of a glass ceramic sample, including the steps of applying energy to the sample using an excitation source, detecting raw Raman spectral energy that is given off by the sample using a detector, wherein the raw Raman spectral energy includes peak values, determining a plurality of predetermined energy peaks based off a composition of the sample, superimposing the plurality of predetermined energy peaks over the raw Raman spectral energy, applying a baseline value between each predetermined energy peak, subtracting the baseline value from the raw Raman spectral energy, calculating corrected peak values based on the raw Raman spectral energy and baseline value, and determining the crystal phases of the glass ceramic sample based on the corrected peak values.

Abstract: A measurement apparatus includes: a light source configured to irradiate a measurement region of skin whose color is to be measured with light; a light receiving unit configured to receive reflected light from the measurement region or transmitted light that has passed through the measurement region; a calculation unit configured to repeatedly obtain determination information and color information relating to the color of the measurement region, based on a light-receiving result of the light receiving unit; and a selection unit configured to select a measurement result of a color of the skin from the repeatedly-obtained color information, based on a temporal change in the determination information.

Abstract: An apparatus for particle characterisation, comprising: a sample cell for holding a sample; a light source configured to illuminate the sample with an illuminating beam and a plurality of light detectors, each light detector configured to receive scattered light resulting from the interaction between the illuminating beam and the sample along a respective detector path, wherein each respective detector path is at substantially the same angle to the illuminating beam.

Abstract: A spectroscopic analysis device includes a light source configured to emit light including a plurality of wavelength components, a polarizer configured to convert the light emitted from the light source to a light of linearly polarized light to be radiated to a sample, a polarizing diffraction element configured to diffract and spectrally disperse a first polarization component included in the light having passed through the sample in a first direction, the polarizing diffraction element being configured to diffract and spectrally disperse a second polarization component included in the light in a second direction different from the first direction, a prism which is disposed on an exit side of the polarizing diffraction element and which has a first exit surface crossing the first direction and a second exit surface crossing the second direction, and in which angles of the first exit surface and the second exit surface with respect to a reference plane including the first direction and the second direction ar

Abstract: The present invention provides a spectral imaging device characterized in that N images are captured with ambient light, and spectra can be obtained from the captured N images for spectral analysis. In particular, a filter device is employed to divide a spectral range of the ambient light into N spectral bands, and each capture corresponds to one spectral band.

Abstract: An optical apparatus has an OCT imaging apparatus with a first light source for low coherence light of wavelengths above a threshold wavelength and a signal detector that obtains an interference signal between low coherence light from the sample and low coherence light reflected from a reference. A surface contour imaging apparatus has a second light source that emits one or more wavelengths of surface illumination below the threshold wavelength, a camera to acquire images from illumination reflected from the sample and a probe that has a raster scanner wherein the low coherence light and the surface illumination share the same path from the raster scanner to the sample. A processor coordinates activation of the light sources, actuation of the scanner, and acquisition of data and the camera and follows instructions to display, store, or transfer images from the acquired data.