Abstract: The compounds of the invention have the formula ##SPC1##Wherein Y is a radical of the formula ##SPC2##Wherein n is 1, 2, 3, 4, 5, or 6, m is 0 or 1, and R.sup.5 is hydrogen or alkyl of 1 to 3 carbons;R.sup.1, r.sup.2, r.sup.3 and R.sup.4 are the same or different and are alkanoyl of 1 to 4 carbons; haloalkanoyl of 1 to 4 carbons; or alkoxycarbonyl of the formula ##EQU1## wherein R is an alkyl radical of 1 to 4 carbons; R.sup.7 and R.sup.8 are the same or different and are hydrogen or alkyl having 1 to 4 carbon atoms; andR.sup.9 is hydrogen or a straight or branched chain alkyl radical having 1 to 6 carbon atoms.These compounds have been found useful in the treatment of hypertension in mammalian species, as surface active agents, as in vivo antibacterial compounds and as water softeners.

Abstract: A process for the preparation of a cyanophenol of formula (I) ##SPC1##wherein Z is a substituent in the 4- or 6-position with respect to the hydroxy group, characterized in that cyanide ions are reacted in a dipolar aprotic solvent with a nitrobenzene of formula (II) ##SPC2##wherein Z has the same value as in formula (I) and is a group, other than a nitro group, known to withdraw electrons in substitution reactions and which does not contain a proton capable of ionizing under the defined reaction conditions if such ionization would inhibit the electron-withdrawing effect of the group Z.In formula (I) and (II) the benzene ring is optionally substituted by one or more non electron-withdrawing groups, or by one or more electron-withdrawing groups provided that such electron-withdrawing groups are in positions other than the 4- and 6-positions with respect to the hydroxy group.

Abstract: Compounds of the formula ##SPC1##WhereinR is straight or branched alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 2 carbon atoms or phenyl, andn is an integer from 2 to 4, inclusive,And non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as non-narcotic analgesics.

Abstract: Disclosed herein is an improved process for the preparation of known hypoglycemic piperidinesulfamylureas of the structure ##EQU1## wherein R is selected from the group consisting of 3-(2-methoxy)pyridyl, 3-(2-ethoxy)pyridyl and 2-(4-chloro)pyridyl and R' is selected from the group consisting of bicyclo[2.2.1]hept-5-en-2-yl-endo-methyl, bicyclo[2.2.1]hept-2-yl-endo-methyl, 7-oxabicyclo[2.2.1]hept-2-yl-methyl, 1-adamantyl and cycloalkyl having from five to eight carbon atoms.Said process comprises contacting 4-(2-pyridyl-amidoethyl) piperidine of the structure ##EQU2## with substantially one equivalent of sulfamide thereby exclusively sulfonating the piperidine nitrogen atom.

Abstract: This invention relates to a class of phthalein indicator dyes useful as optical filter agents in photographic processes to protect a selectively exposed photosensitive material from further exposure during processing in the presence of incident light. Such dyes comprise 3,3-disubstituted phthalides and 3,3-disubstituted naphthalides wherein one of said 3,3 substituents is a carbazol-3-yl radical and the other is an indol-3-yl radical possessing a hydrogen-bonding group substituted on a carbon atom adjacent to the heterocyclic N atom, both of said carbazolyl and indolyl radicals having hydrogen substituted on the heterocyclic N atom.

Abstract: Disclosed are various phenyl -thiourea, -carbothioamide and -carbonothioamide derivatives which are useful in alleviating symptoms and conditions of inflammation.

Abstract: Nitrosobenzene or Azoxybenzene are heated at temperatures above about 400.degree.C. to produce various phenylamines and carbazoles.

Abstract: 2-Allyloxy-4-chloro-.beta.-piperidinopropiophenone is prepared by reacting 2-allyloxy-4-chloroacetophenone with piperidine and formaldehyde. 2-Allyloxy-4-chloro-.beta.-piperidinopropiophenone is useful as an antitussive.

Abstract: 3-(N-acyl-N-arylamino)-.gamma.-lactones, .delta.-lactones, .gamma.-lactams and .delta.-lactams have fungicidal activity.

Abstract: This invention relates to a new class of indicator dyes useful as optical filter agents in photographic processes to protect a selectively exposed photosensitive material from further exposure during processing in the presence of incident light. Such dyes comprise 3,6-disubstituted carbazoles wherein the 3,6 substituents are selected from a phthalidyl radical, C.sub.6 H.sub.4.CO.O.CR--, wherein R is an aryl group and an o-carboxybenzoyl radical, not more than one of said substituents being o-carboxybenzoyl.

Abstract: The compounds are sulphoxides of heterocyclicthioalkylthioureas, ureas and guanidines which are useful to produce inhibition of histamine H-2 receptors.

Abstract: 3-[1-Hydroxy-2-(3- or 4-hydroxypiperidino)ethyl]-5-phenylisoxazole synthesized from 3-(1,2-epoxyethyl)-5-phenylisoxazole or 3-(1-hydroxy-2-active group-substituted ethyl)-5-phenylisoxazole with 3- or 4-hydroxypiperidine, or 3-(3- or 4-hydroxypiperidino)acetyl-5-phenylisoxazole or 3-(3- or 4-ketopiperidino)acetyl-5-phenylisoxazole by reduction showing strong analgesic and anti-inflammatory activities with low toxicity.

Abstract: 4-Imidazolylsulfonamides and 4-imidazolylsulfonylimidazoles are useful as plasticizers. These compounds are obtained by reaction of 4-imidazolesulfonyl chloride with an amine, such as imidazole. 4-Imidazolesulfonyl chloride itself is useful as a reactant with textile materials such as cotton to increase flame resistance.

Abstract: Improved preparation of Wittig salts of alpha,beta-unsaturated alcohols by treating the alcohol with a phosphine in a basic medium and in the presence of a salt of a weak organic base with a strong acid. The Wittig salt may be reacted further with an unsaturated aldehyde to form a polyene compound.

Abstract: The novel bis-basic ethers of carbazole of the present invention have useful antiviral properties. These new compounds are represented by the formula ##SPC1##Wherein Z is hydrogen or lower alkyl having from 1 to 4 carbon atoms; and each X is ##EQU1## A. the group -A-N wherein each A is a straight or branched alkylene chain having from 2 to 6 carbon atoms; R and R.sup.1 are individually hydrogen or lower alkyl having from 1 to 6 carbon atoms; or each set of R and R.sup.1 taken together with the nitrogen atom to which they are attached is a saturated monocyclic heterocyclic group such as pyrrolidino or piperidino; orB. the group ##SPC2##Wherein n is a whole integer from 0 to 2, m is 1 or 2, and R.sup.2 is hydrogen or lower alkyl having from 1 to 4 carbon atoms.This invention also includes pharmaceutically acceptable acid addition salts of the bases represented by Formula I. These new compounds may be prepared by several different methods which are described.

Abstract: 3-(Dimethylamino)-1,2,3,4,8,9-hexahydro-1H[1]benzazepino[1,2,3-k,j]carbazol e and acid-addition salts thereof having anti-bacterial activity, and process for the preparation thereof are disclosed.

Abstract: Novel compounds useful as antihistamine agents, antiallergy agents, and bronchodilators are represented by the following formula ##SPC1##Wherein R.sup.1 represents cyclohexyl, phenyl, or substituted phenyl wherein the substituent on the substituted phenyl is selected from halogen, a straight or branched lower alkyl group of from 1 to 4 carbon atoms, or a lower alkoxy group of from 1 to 4 carbon atoms; R.sup.2 represents hydrogen or hydroxy; R.sup.3 represents hydrogen; or R.sup.2 and R.sup.3 taken together form a second bond between the carbon atoms bearing R.sup.2 and R.sup.

Abstract: Compounds of the formula ##SPC1##Wherein R is hydrogen, methyl or acetyl,R.sub.1 and R.sub.2, which may be identical to or different from each other, are each alkyl of 1 to 3 carbon atoms,R.sub.3 is hydrogen or methyl, andY is oxygen or sulfur,And non-toxic, pharmacologically acceptable acid addition salts thereof; these compounds as well as the salts are useful as analgesics and antitussives, and opiate antagonists.

Abstract: Novel benzofuran containing a benzimidazolyl group are obtained by reacting a benzofuran containing a carboxylic acid halide group with either an ortho-phenylene diamine or an ortho-nitro-aniline derivative, in the latter case reducing the nitro intermediate to the corresponding (aminophenyl)-amide and splitting off water by closing the imidazole ring. The products are optical brighteners, especially for acrylonitrile polymers.

Abstract: 4,5,6,7-Tetrachloro-2-thio-phthalide of the formula ##SPC1##Which possesses fungicidal and bactericidal properties.