Abstract: An incontinence device is used to apply supporting pressure to an anterior wall of an inferior third of a vaginal canal in the approximate plane of a pubococcygeal muscle and ultimately to a urethra for controlling incontinence. The incontinence device includes a first member having a first end and second end, as well as a second member resiliently connected to the first member. The second member is biased outwardly from the first member to direct the first end of the first member toward the anterior wall of the vaginal canal in a manner providing a support structure transferring upward force for support of the urethra by the first end of the first member.

Abstract: Materials and methods for enhancing the effectiveness of proton radiation therapy (e.g., high linear energy transfer (LET) proton radiation therapy) against tumor cells are provided herein.

Abstract: The present disclosure pertains to a system configured to facilitate prediction of a sleep stage and intervention preparation in advance of the sleep stage's occurrence. The system comprises sensors configured to be placed on a subject and to generate output signals conveying information related to brain activity of the subject; and processors configured to: determine a sample representing the output signals with respect to a first time period of a sleep session; provide the sample to a prediction model at a first time of the sleep session to predict a sleep stage of the subject occurring around a second time; determine intervention information based on the prediction of the sleep stage, the intervention information indicating one or more stimulator parameters related to periheral stimulation; and cause one or more stimulators to provide the intervention to the subject around the second time of the sleep session.

Abstract: Devices and methods for providing localized pressure to a region of a patient's heart to improve heart functioning, including: (a) a jacket made of a flexible biocompatible material, the jacket having an open top end that is received around the heart and a bottom portion that is received around the apex of the heart; and (b) at least one inflatable bladder disposed on an interior surface of the jacket, the inflatable bladder having an inelastic outer surface positioned adjacent to the jacket and an elastic inner surface such that inflation of the bladder causes the bladder to deform substantially inwardly to exert localized pressure against a region of the heart.

Abstract: A device determines values for one or more metrics that indicate the quality of a patient's sleep based on sensed physiological parameter values. Sleep efficiency, sleep latency, and time spent in deeper sleep states are example sleep quality metrics for which values may be determined. The sleep quality metric values may be used, for example, to evaluate the effectiveness of a therapy delivered to the patient by a medical device. In some embodiments, determined sleep quality metric values are automatically associated with the therapy parameter sets according to which the medical device delivered the therapy when the physiological parameter values were sensed, and used to evaluate the effectiveness of the various therapy parameter sets. The medical device may deliver the therapy to treat a non-respiratory neurological disorder, such as epilepsy, a movement disorder, or a psychological disorder. The therapy may be, for example, deep brain stimulation (DBS) therapy.

Abstract: A system and method for facilitating and maintaining various states of a user consciousness, including the transition between a conscious and unconscious state, is provided. The system and method include use of a smart device having a user interface, a biometric sensor coupled to a user and configured to transmit the user's biometric data to the smart device and an environmental sensor configured to transmit environmental data to the smart device. The smart device controls one or more environmental systems proximate the user and an audio/visual device proximate the user to facilitate transitioning the state of the user.

Abstract: In various embodiments methods and devices are provided for facilitating locomotor function and/or voiding of bladder and/or bowel in a subject with a neuromotor disorder. In certain embodiments the methods involve providing magnetic stimulation of the spinal cord at a location, frequency and intensity sufficient to facilitate locomotor function and/or voiding of bladder and/or bowel.

Abstract: A device for influencing biological sequences in living tissue, in particular a human body, includes a field generation device for generating the pulsating magnetic field to be applied to at least a part of the tissue, and a pulse generator controlling the field generation device. The pulsating magnetic field is composed of a sequence of primary pulses which are formed by a plurality of superimposed sub-pulses, the pulse repetition rate of which is between 0.01 and 1000 Hz. The sequence of primary pulses separated is from a second sequence of primary pulses by a rest phase. The curve profile of the maximum amplitude of the primary pulses has a slope mB of ??<mB<?0.1 at the beginning of the rest phase and/or has a slope mE of ?>mE>0.1 at the end of the rest phase.

Abstract: Aspects of the present disclosure provide methods, apparatuses, and systems for dynamically masking audible breathing noises determined to be generated by one or more sleeping partners. According to aspects, a subject's sleep is protected by detecting audible breathing noises in a sleeping environment, determining the audible breathing noises are not generated by the subject, and mitigating the perception of the audible breathing noises that are determined to originate from another subject, such as a bed partner, pet, etc. The dynamic masking reduces the subject's exposure to unnecessary sounds and reduces the chances of masking sounds disturbing the subject's sleep.

Abstract: An aerosol containment enclosure is used to isolate an air mass immediately surrounding a patient known or suspected to have a disease which may be transmitted through the air. The enclosure cooperates with a patient support apparatus. In embodiments, a flexible rod supports a substantially aerosol impermeable covering and is connected to the patient support apparatus. The enclosure is collapsible to a predetermined collapsed shape and expandable to a predetermined erect shape. In embodiments, a portal in the covering provides access for care personnel or equipment. The aerosol containment enclosure is lightweight, compact, and partially or fully disposable. The enclosure may be rapidly erected around a patient in an ambulance or other treatment setting.

Abstract: A therapeutic device that can diffuse essential oils, infuse frequency into liquids, emit frequency-driven lights, and produce solfeggio tones. The therapeutic device includes an enclosure, at least one oil-diffusing device, at least one frequency-infusing device, at least one frequency-tone generator, a first plurality of ambience lights, at least one vent, and a first controller. The enclosure is used to conceal and protect the electronic components. The at least one oil-diffusing device is used to diffuse fluids. The at least one frequency-infusing device is used to infuse frequency by vibration into fluids. The at least one frequency-tone generator is used to generate tones of different frequencies. The first plurality of ambience lights is used for aesthetic and therapeutic aspects. The at least one vent is used as an escape for the mist produced by the diffusion of the fluids. The first controller is used to manage the electronic components.

Abstract: A method of controlling a biometric parameter, such as heart rate and/or breathing rate, of a subject engaged in an activity includes sensing the biometric parameter via a monitoring device worn by the subject, determining frequency characteristics of the biometric parameter, and presenting to the subject musical audio having a tempo correlated to the frequency characteristics of the biometric parameter. The tempo of the musical audio presented to the subject may be changed in order to cause a change in the biometric parameter. A method of modulating heart rate of a subject engaged in an activity includes sensing a breathing rate of the subject via a monitoring device worn by the subject, and then presenting to the subject musical audio having a tempo selected to change the breathing rate by an amount sufficient to cause a change in the heart rate.

Abstract: An occlusion system implantable in a human or animal body, including a fluidic circuit which includes an inflatable occlusive sleeve, a reservoir with variable volume filled with a fluid. The reservoir includes a fixed portion and a movable portion, an actuator mechanically coupled with the movable portion of the reservoir to linearly displace the movable portion relative to the fixed portion for adjusting the volume of the reservoir. The actuator and the reservoir are laid out in a sealed casing containing a gas. A sensor mechanically bound to the actuator and/or to the movable portion, measures a traction and/or compressive force of the movable portion of the reservoir. Also included is a device for measuring the fluid pressure in the fluidic circuit.

Abstract: A sleep induction device includes at least one sensor for detecting a physiological characteristic of the user, a stimulator configured to provide successive stimuli to the user to anticipate on the detected physiological characteristic, which successive stimuli define a guidance path, and which guidance path is to be followed by the user to induce a change during the sleep session of the user, a memory which is arranged to store values of detected physiological characteristics, and provided stimuli during the sleep session, and a processing unit including a control programme which is programmed to determine a current sleep state of the user, which current sleep state is based on at least one detected physiological characteristic measured by the at least one sensor and which control programme is programmed to generate an initial guidance path to induce a change from the determined current sleep state to another sleep state.

Abstract: A method of affecting a biological, cellular or biochemical function or structure in a targeted subcortical location in a brain of a patient using a TRPMS apparatus placed on a head of the patient includes positioning two or more of a plurality of magnetic assemblies on locations of the head mount selected to stimulate the targeted subcortical location in the brain of the patient, and activating the plurality of magnetic assemblies at the selected locations to generate magnetic fluxes of a selected strength, frequency and duration directed into the brain of the patient, wherein the magnetic flux directed into the brain of the patient from each of the assemblies is operative to generate induced electric field in regions of the brain and the regions of induced electric fields generated by each of the plurality of magnetic assemblies converge in the targeted subcortical location and combine to a magnitude sufficient to affect the biological, cellular or biochemical function or structure in the targeted subcortic

Abstract: System and methods for therapy involving the use of three-dimensional articles of manufacture having printed media at predetermined locations thereon to overcome a therapeutic issue, such as (but not necessarily limited to) fear, phobias, trauma, addiction, grief, depression, feelings of loss, physical pain and diabetic neuropathy. By using the system and methods of the present invention while focusing on emotional and/or physical pain associated with a therapeutic issue, both hemispheres of the brain are activated and random stimulation via place or grid cells and their associated complex circuits occur, which collectively causes or creates new neural connections in the brain of the patient to thereby diminish or even resolve the emotional and/or physical pain associated with the therapeutic issue.

Abstract: A device for replicating a natural magnetic vibration of Earth, promoting more restful sleep. The device produces an appropriately uniform magnetic field across the surface of the area where the head rests during sleep. The device provides a varying magnetic field therapy that allows a user to sleep in their usual manner using their existing familiar pillow, with no changes to the aesthetics of the bed, while using the device having varying magnetic field therapy capabilities.

Abstract: Provided herein are orthodontic devices and methods for patients whose orthodontic devices are causing a lisp. The device can comprise an aligner configured to fit over a patient's dental arch and comprising an occlusal surface section positioned over an occlusal surface of the patient's teeth. The aligner can comprise a barrier portion extending laterally and adjacent to a region of the dental arch, the barrier portion allowing the patient's tongue to form a seal against the barrier portion when the patient is speaking while wearing the device.

Abstract: Disclosed are micro-wire stimulators that magnetically stimulate nearby cells and/or their processes (e.g., nerve fiber, axons, dendrites, etc.). The micro-wire includes one or more bends. The micro-wire stimulator can facilitate the creation of stronger field gradients in one direction with much smaller gradients in orthogonal directions, allowing for selective targeting, or avoiding, of specific cell types within a targeted region. The bent micro-wire stimulator may be implanted into the cortex of the brain to selectively stimulate nearby neural cells having a particular orientation relative to the stimulator. A tip portion of the micro-wire may be rounded, or it may have corners forming other suitable geometric shapes.

Abstract: An external portion of an auditory prosthesis includes an external magnet that interacts with an implanted magnet to hold the external portion against the skin of a recipient. A magnetic component can be disposed proximate either or both of the external magnet or implanted magnet to channel the magnetic field associated therewith. The magnetic component can be moved relative to its associated magnet so as to adjust the magnetic field, and thus, the retention force between the magnets.