Patents Examined by Susan Hoffman
  • Patent number: 12636338
    Abstract: An areca nut product and preparation method thereof, and an areca nut additive agent are provided. The areca nut product is prepared from areca nuts, citric acid, mature vinegar, chitosan, active zinc oxide, monazite calcined distilled water, bovine bone protein peptide, lipase, isomaltooligosaccharide, soybean lecithin, ginseng, atractylodes macrocephala, poria cocos, liquorice, astragalus, notoginseng, tangerine peel, folium eucommiae, citronella grass, and mucor. Experimental tests shows that the areca nut product of the disclosure has a good antiviral effect, and the areca nut product has good preventive and therapeutic effects on oral diseases; compared with ordinary areca nut products, carcinogenic study has shown that carcinogenicity of the areca nut product of the disclosure has significantly reduced.
    Type: Grant
    Filed: August 16, 2023
    Date of Patent: May 26, 2026
    Assignee: Changde Jizhi Biological Technology Co., Ltd
    Inventor: Xinqiao He
  • Patent number: 12637490
    Abstract: The object of the invention is a method for extracting, with high yield, phycobiliproteins from cyanobacterial and/or algal biomass, obtaining extracts in water or aqueous solutions characterised by high pigment concentration and a purity degree equal to or greater than the food/cosmetic grade (P?2). The method is based on a process characterised by a step of breaking down the cyanobacterial/algal cells by ultrasonication in an aqueous solution of ammonium sulphate, and simultaneous extraction of water-soluble compounds other than phycobiliproteins, followed by an extraction step of the phycobiliproteins using water or aqueous solutions.
    Type: Grant
    Filed: December 22, 2021
    Date of Patent: May 26, 2026
    Assignee: Consiglio Nazionale delle Ricerche
    Inventors: Rosaria Lauceri, Graziella Chini Zittelli, Giuseppe Torzillo
  • Patent number: 12629401
    Abstract: A method for preparing ginseng extract rich in rare ginsenosides is disclosed. Ginseng roots or ginseng stems and leaves are extracted, enzymatically hydrolyzed and treated with high temperature and high pressure. The preparation method can quickly and effectively increase the proportion of rare ginsenosides in the ginseng extract. After in vitro antioxidant experiments and in vivo experiments with Hidradenitis elegans nematode, the extract and related complexes were proved to be effective in antioxidant, anti-oxidative stress, and improving age-related muscle decline and other dysfunctions. After genetic and metabolomic studies, the anti-aging mechanism was proved to be related to the expression of genes associated with nutrient sensing, stress-related pathways and redox processes, and showed innate immune response and redox process GO enrichment, proving its oxidative stress resistance.
    Type: Grant
    Filed: December 19, 2023
    Date of Patent: May 19, 2026
    Assignees: Chenland Nutritionals Inc., Qingdao Marine Energizing Biotechnology Development Co., Ltd.
    Inventors: Shengcan Zou, Dongli Yin, Jinli Chen, Jinli Liu, Decui Yin, Haijun Zhang
  • Patent number: 12629402
    Abstract: An insoluble cell fraction obtained from plant cells cultured in a suspension composed entirely of natural molecules for the treatment of primary and recurrent Clostridium difficile infections is provided. A process for the preparation of the insoluble cell fraction is also provided.
    Type: Grant
    Filed: May 14, 2020
    Date of Patent: May 19, 2026
    Assignee: ABRESEARCH SRL
    Inventors: Renzo Dal Monte, Andrea Carpi, Ignazio Castagliuolo, Paola Brun
  • Patent number: 12622928
    Abstract: Disclosed herein is a nanovesicles from adult stem cells containing iron nanoparticles and its use. The nanovesicle according to the present disclosure provides effects of maximizing the efficacy of treating mesenchymal stem cells by pretreating cells with iron nanoparticles; reconstituting the cells in a nano-sized form to facilitate intravenous injection; and increasing the efficiency of targeting disease areas through magnet induction. In particular, the present disclosure can replace mesenchymal stem cells as a cell therapeutic agent, and it can be applied to various diseases as a novel biopharmaceutical drug because it can increase the function and efficiency of an exosome-based therapeutic agent.
    Type: Grant
    Filed: January 29, 2019
    Date of Patent: May 12, 2026
    Assignees: Seoul National University R&DB Foundation, Sungkwang Medical Foundation
    Inventors: Byung-Soo Kim, Han Young Kim, In Bo Han, Hemant Kumar
  • Patent number: 12605408
    Abstract: Disclosed is a production method of a product that is developed for treatment of hair loss, alopecia areata (pelade or ringworm), androgenetic alopecia (AGA), hair follicle nourishment, scalp nourishment and scar, scar tissue, eczema, acne treatments, for neurodegenerative, inflammatory diseases and for immune modulation purposes (regulation of the immunological response against inflammation of human tissues and fluids, for regeneration purposes). In particular, the disclosed is a method for the production of a chemical-free product with amniotic fluid content, which has been standardized by pooling and then freeze-dried and gamma irradiated (pooled/cocktail and gamma irradiated amnion-OTIA 1.0), that has been developed to be used in the treatment of ailments such as hair loss, alopecia areata (pelade), androgenetic alopecia (AGA), hair follicle nutrition, scalp nourishment, scar, scar tissue, eczema and acne.
    Type: Grant
    Filed: June 24, 2022
    Date of Patent: April 21, 2026
    Inventors: Ercüment Ovali, Gamze Tümentemur
  • Patent number: 12594313
    Abstract: The present disclosure relates to a composition for treating, preventing or alleviating cardiovascular disease and/or osteoporosis, which contains a mixed extract of hop and Cynanchum wilfordii as an active ingredient, and a method for treating or alleviating cardiovascular disease and/or osteoporosis. The composition and method of the present disclosure provide superior effect of alleviating, preventing or treating cardiovascular disease and/or osteoporosis while using a small amount of hop.
    Type: Grant
    Filed: April 4, 2023
    Date of Patent: April 7, 2026
    Assignee: LG HOUSEHOLD & HEALTH CARE LTD.
    Inventors: Dong-Jun Park, Eun-Mi Sun, Hong-Gu Lee, Ho-Song Cho
  • Patent number: 12582674
    Abstract: Methods for the reversal of hemorrhagic shock or hemorrhagic trauma. Methods for reducing levels of aspartate aminotransferase (AST) and alanine aminotransferase (ALT) in a trauma patient through the administration of stored oxygen reduced blood products.
    Type: Grant
    Filed: January 9, 2023
    Date of Patent: March 24, 2026
    Assignee: Hemanext Inc.
    Inventors: Andrew Dunham, Tatsuro Yoshida
  • Patent number: 12569527
    Abstract: The present invention refers to a biomass of T. chuii and a pharmaceutical composition comprising a biomass of T. chuii for use in the treatment of infertility in a male subject. It also refers to a method for increasing the quality of the semen of a male subject having normozoospermia, not having hypospermia and not having a disorder characterized by a high percentage of sperm DNA fragmentation (SDF), that comprises the administration of a biomass of T. chuii.
    Type: Grant
    Filed: July 9, 2021
    Date of Patent: March 10, 2026
    Assignee: FITOPLANCTON MARINO, S.L
    Inventors: Carlos Unamunzaga Escosura, Eulalia Mantecón Gálvez, Carlos Infante Toscano
  • Patent number: 12564551
    Abstract: The present invention relates generally to a composition or an oat extract comprising at least one avenanthramide compound or an analogue thereof and at least one ?-glucan compound at predetermined ratios and having a low salt content. In addition, the present invention relates to a method for preparing such an oat extract, an oat extract obtained by said method, and the use of said composition or oat extract for the preparation of foods, food supplements, cosmetic, pharmaceutical or veterinary preparations. Finally, the present invention relates to foods, food supplements, cosmetics, pharmaceuticals or veterinary preparations comprising said composition or oat extract.
    Type: Grant
    Filed: March 6, 2020
    Date of Patent: March 3, 2026
    Assignee: SYMRISE AG
    Inventors: Martina Herrmann, Holger Joppe
  • Patent number: 12564606
    Abstract: The present invention relates to a pharmaceutical composition for treating wounds, containing a silk protein and a plasma component as active ingredients. According to the present invention, wounds can be more effectively healed by using synergistic effects of a silk protein and a plasma component.
    Type: Grant
    Filed: November 21, 2019
    Date of Patent: March 3, 2026
    Assignees: MEDICOSBIOTECH, INC, KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sang Yup Lee, Won Min Yoo, Sooncheol Kim, Hannah Chung, Jiyong Kim
  • Patent number: 12558390
    Abstract: The invention provides unique compositions containing mixtures of extracts from medicinal plants and animal parts, as well as related uses for improving health and treating diseases. The inventive compositions provide a wide range of health benefits in the human body in comparison to effects from individual components contained therein.
    Type: Grant
    Filed: November 20, 2022
    Date of Patent: February 24, 2026
    Inventor: Ming Jie Wu
  • Patent number: 12558394
    Abstract: Application of a traditional Chinese medicine composition to preparation of a medicine for treating or preventing coronavirus infection. The traditional Chinese medicine composition includes: 5-30 parts of Herba houttuyniae, 5-30 parts of Flos lonicerae, 5-20 parts of Radix paeoniae rubra, 3-15 parts of Folium artemisiae argyi and 3-15 parts of Herba menthae. The traditional Chinese medicine composition has a good effect of treating or preventing coronavirus-related diseases.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: February 24, 2026
    Assignee: JIANGSU KANION PHARMACEUTICAL CO., LTD.
    Inventors: Wei Xiao, Xiaoqian Tao, Xinzhuang Zhang, Zhenzhen Su, Zhipeng Ke, Zeyu Cao, Liang Cao, Xiaolian He, Xuehong Dong, Yanqiu Wang
  • Patent number: 12543733
    Abstract: The present invention relates to a composition having strong insecticidal activity and a process of preparation thereof. More particularly, the present invention relates to a novel biofumigant composition and a process for the preparation of a biofumigant. The biofumigant composition is eco-friendly, biodegradable. Further, the biofumigant composition is effective against stored product insects such as Sitophilus oryzae, Corcyra cephalonica and Tribolium castaneum. Moreover, since the biofumigant does not result in any adverse effect on the seed germination and growth of plant, therefore the composition is found to be highly desirable for grain protection against stored-product insect pests.
    Type: Grant
    Filed: November 10, 2021
    Date of Patent: February 10, 2026
    Assignee: INSTITUTE OF BIORESOURCES AND SUSTAINABLE DEVELOPMENT
    Inventors: Bunindro Nameirakpam, Sonia Sougrakpam, Y. Rajashekar, Jharna Chakravorty, Pulok K. Mukherjee
  • Patent number: 12544416
    Abstract: Disclosed herein is a method for manufacturing a composition promoting bone density enhancement, the method including preparing a mixture of Angelica gigas, Cnidium officinale, Phlomis umbrosa, Astragalus membranceus, Amomi fructus, Citri unshius pericarpium, Drynariae rhizoma, Codonopsis pilosulae radix, frankincense, and myrrh, aging the mixture, drying the mixture and grinding the dried mixture into a powder, and extracting a liquid from the powder.
    Type: Grant
    Filed: December 19, 2023
    Date of Patent: February 10, 2026
    Inventor: Man Ki Hwang
  • Patent number: 12538930
    Abstract: A weight loss supplement composition is disclosed. The composition comprises a first pre-defined amount of dairy product such that the dairy product is a heavy and lactose-free whipping cream; an effective amount of sugar-free flavoring extract; and a second pre-defined amount of isolate whey protein; wherein the first pre-defined amount of the dairy product, the effective amount of the sugar-free flavoring extract, the second pre-defined amount of the isolate whey protein are mixed to a desired consistency for preparing a weight loss supplement.
    Type: Grant
    Filed: March 22, 2024
    Date of Patent: February 3, 2026
    Inventor: John J Murphy
  • Patent number: 12539268
    Abstract: Non-therapeutic methods of improving an individual's mood and of treating sensitive skin are provided.
    Type: Grant
    Filed: February 29, 2020
    Date of Patent: February 3, 2026
    Assignee: GIVAUDAN SA
    Inventors: Anne Humeau, Romain Reynaud, Amandine Scandolera
  • Patent number: 12533385
    Abstract: Use of a mulberry extract in the preparation of a product for treating and/or improving polycystic ovarian syndrome. It is demonstrated in the experiment that the mulberry twig alkaloids can reduce the ovarian weight of rats with polycystic ovarian syndrome and improve the ovarian pathology, regulate the estrous cycle of rats with polycystic ovarian syndrome in the intervention process, and can remarkably adjust the secretion level of sex hormones in rats with polycystic ovarian syndrome.
    Type: Grant
    Filed: March 3, 2023
    Date of Patent: January 27, 2026
    Assignees: BEIJING WEHAND-BIO PHARMACEUTICAL CO., LTD, GUANGXI WEHAND-BIO PHARMACEUTICAL CO., LTD
    Inventors: Yuling Liu, Yuanyuan Liu, Huijuan Li, Dongdong Liu, Zhihua Liu, Xingang Wang, Yanmin Chen, Tingting Wang, Yuanyuan Zou, Hongzhen Yang, Lili Gao
  • Patent number: 12527813
    Abstract: A method of treating a vulnerable atherosclerotic plaque can include identifying the vulnerable atherosclerotic plaque and administering a sulfated polysaccharide, or a pharmaceutically acceptable salt thereof, to a subject in an amount and at a frequency sufficient to stabilize and reverse a vulnerable atherosclerotic plaque.
    Type: Grant
    Filed: October 5, 2021
    Date of Patent: January 20, 2026
    Assignee: Calroy Health Sciences, LLC
    Inventors: Chen Chen, Miao Zhang, Edward Hoyt, Kevin Chen
  • Patent number: 12527828
    Abstract: A traditional Chinese medicine composition for recovery phase of exogenous fever and a preparation method therefor. The traditional Chinese medicine composition comprises the following raw materials: radix codonopsis, rhizoma atractylodis macrocephalae, poria cocos, radix ophiopogonis, schisandra chinensis, hairyvein agrimony, perilla seeds, cortex moriradicis, folium eriobotryae, radix platycodi, apricot kernels, and radix glycyrrhizae. According to the monarch, minister, assistant and guide theory of traditional Chinese medicines, the radix codonopsis is used as a monarch drug; fried rhizoma atractylodis macrocephalae, the poria cocos, the radix ophiopogonis, the schisandra chinensis, and the hairyvein agrimony are used as minister drugs; the perilla seeds, the cortex moriradicis, and the folium eriobotryae are used as assistant drugs; and the radix platycodi, the apricot kernels, and the radix glycyrrhizae are used as guide drugs.
    Type: Grant
    Filed: March 25, 2021
    Date of Patent: January 20, 2026
    Assignee: BEIJING UNIVERSITY OF CHINESE MEDICINE THIRD AFFILIATED HOSPITAL
    Inventors: Chengxiang Wang, Hongsheng Cui, Weiheng Chen, Huiyong Yu, Jianjun Wu