Abstract: A patient's acceptance of transplanted organs and tissues may be enhanced by treating donor specific blood with a suitable dose of ultraviolet radiation for an appropriate period of time, transfusing the irradiated blood into the patient during a suitable pretransplantation time period and then transplanting the organ or tissue into the subject. Acceptance of transplanted organs and tissues can also be enhanced by treating the organs or tissues to be transplanted with a suitable dose of ultraviolet radiation for an appropriate period of time and then transplanting the organ or tissue. Suitably irradiated donor specific blood, organs and tissues are preferred for use in transplantation.
Type:
Grant
Filed:
June 12, 1989
Date of Patent:
August 7, 1990
Assignee:
The Trustees of Columbia University in the City of New York
Inventors:
Keith Reemtsma, Mark A. Hardy, Henry T. Lau
Abstract: An apparatus for diluting a sample with a diluent, comprising a fixed volume measuring chamber, a fixed volume receiving chamber and fluid receiving relationship to the measuring chamber, a gas vent in the receiving chamber, a stop flow junction between the measuring chamber and the receiving chamber, a sample application site in fluid donating relationship to the measuring chamber, wherein the vertical height difference between the sample application site and the stop flow junction is insufficient to provide a hydrostatic pressure capable of overcoming backpressure at the stop flow junction when sample is applied to the sample application site, and the diluent application site and fluid donating relationship to the measuring chamber. Sample and diluent are added sequentially to the apparatus of the invention without requiring any intervening operations. Various means are provided for restarting flow, which causes diluent to wash the sample into the receiving chamber, where the two can be mixed.
Type:
Grant
Filed:
August 18, 1989
Date of Patent:
August 7, 1990
Assignee:
Biotrack, Inc.
Inventors:
Ian Gibbons, Robert S. Hillman, Channing R. Robertson, Jimmy D. Allen
Abstract: A liquid control standard for the use in the qualilty assurance of blood analysis instrumentation systems is disclosed. The liquid control standard is able to act as a control standard for blood gas instrumentation systems measuring pH, pCO.sub.2 and pO.sub.2 of blood, as a liquid control standard for ion selective electrode instrumentation systems for the measuring of electrolytes such as ionized calcium and total calcium as well as Na, K and Li ions in the blood and, optionally, as a control standard for a co-oximeter measuring the amount of total hemoglobin present in the blood and the relative amounts of other hemoglobin fractions present in the blood.
Abstract: A process for inhibiting the deposit of paraffins in crude oils and petroleum fractions incorporating additives of the family of N-substituted succinimide ethers. The additives according to the invention make it possible, on the one hand, to maintain in dispersion the whole range of paraffins improving the flowing properties of crude oils and, on the other, to prevent the deposit of the heavier paraffins on the walls. Therefore, the process is effective during both the storage and the transportation of crude petroleum.
Type:
Grant
Filed:
July 12, 1984
Date of Patent:
June 26, 1990
Assignee:
Societe Nationale Elf Aquitaine
Inventors:
Bernard Damin, Alain Faure, Paul Maldonado, Jean-Luc Volle
Abstract: An antimicrobial solution of a microbiologically active organo sulfonyl ethylene, isoindole dicarboximide or zinc hydroxypyridine thionate dissolved in an organo phosphorus compound selected from the group consisting of organophosphites and organophosphonates.
Abstract: A method for classifying leukocytes with a flow cytometer by means of optical measurements on fluorochrome-stained blood cells is useful in the practice of clinical testing.
Abstract: A procedure for controlling cellulose digestion by measuring activity of chemicals essentially influencing the cellulose digestion and which are present in a cellulose digester. Feeding of chemicals to be added into the cellulose digester is controlled on the basis of the measurement results. The measurement is carried out by placing, in the cellulose digester, one or several measuring electrodes and reference electrodes, and a current-supplying counterelectrode. Current is supplied to the thus-established circuit from a current source, in a manner such that the voltage across the measuring electrode and the reference electrode, in other words the electrochemical potential of the measuring electrode, is substantially constant. The current intensity corresponding to such potential is directly proportional to activity of the chemicals in the cellulose digester. A method for measuring the cellulose digestive activity is also provided in accordance with the present invention.
Abstract: A shaking apparatus for agitating and withdrawing a liquid specimen such as blood confined in a sealed vessel, the apparatus including vessel catching hand whereby the vessel is held under the action of a spring and is shaked so as to effect the agitation of the content, and after agitation is finished the content is withdrawn without opening the vessel through needles stabbled through the plug thereof. The needles are cleansed so as not to spoil the specimen contained in the vessel.
Abstract: This invention provides a new fermentation method and apparatus for the same for producing a substance by a microbial action from a gaseous substrate, wherein the cells of a microorganism fixed to a carrier are held in a reactor, an aqueous solution is fed to said reactor so as to moisten at least part of the surface of said microbial cells, and said gaseous substrate is forced to pass through the interstices of said microbial cells, thereby causing direct reaction between the microorganism and the gaseous substrate and effecting efficient biosynthesis of methane, formic acid and other substances.
Abstract: The process provides the enzymatic phosphorylation of glucose to FDP by means of yeast immobilized by glutaraldehyde and the separation of FDP by ultrafiltration. A suspension of glutaraldehyde-treated yeast is fed to a fermenter, with addition of a nutrient mixture consisting of dextrose (1M), sodium phosphate (0.5 M), magnesium chloride (10 mM) and phosphoric acid until pH 6.5. The mixture is re-circulated through a hollow fiber ultrafiltration unit to separate the FDP that forms during the phosphorylation reaction.
Abstract: A gas chromatograph is converted into a thermal extraction pyrolysis gas chromatograph by adding a temperature progarmmable sleeve around the injection column. Minimal modification to existing nonthermal extraction/nonpyrolysis gas chromatographs is required.
Type:
Grant
Filed:
May 31, 1988
Date of Patent:
April 24, 1990
Assignee:
Amoco Corporation
Inventors:
Eric L. Bandurski, Phach F. N. Vu, Gary D. Bruce
Abstract: Protein hydrolysates are described; they may be obtained by the enzymatic decomposition of whey protein, lactalbumin, .alpha.-lactalbumin, .beta.-lactoglobulin, lysozyme, lactoferrin or serum albumin. These products are suitable for pharmaceutical purposes.
Abstract: An apparatus for collecting and transporting dual biological samples such as blood and urine comprising an impact resistant outer container having a soft foam cushioning pad disposed across the bottom, and a thicker protective collar of dense foam placed on top of the cushioning pad. The protective collar defines bores extending therethrough and sized to receive a tamper resistant sealed specimen vial and lid assembly, a pair of blood sampling tubes, and a multi-sample sterile syringe assembly. An instruction manual, tamper evidencing sealing tapes, and a non-alcoholic swab are enclosed in the outer container, along with an upper cushioning pad similar to that at the bottom of the container. The outer container is then closed with a lid and sealed in a temper evidencing wrapper.
Type:
Grant
Filed:
June 27, 1988
Date of Patent:
April 17, 1990
Assignee:
Forensic Applications Corporation
Inventors:
Richard E. Jensen, Donald H. Nichols, D. Gary Hemphill
Abstract: A disposable indwelling catheter placement unit includes a transparent plastic catheter for insertion into a blood vessel having depth indicating graduations thereon. The catheter is freely slidable into a transparent plastic tubular sheath having a slit line there along. The unit has a transparent inserter having an inner tube connected to a front portion of the inserter. The sheath tube is releasable from around the catheter responsive to movement through the inserter. By pushing the sheath tube forward into the inserter with the fingers while holding the inserter with other fingers, or pulling the split sheath from the inserter, the catheter can be pushed into the blood vessel up to a desired depth while maintaining sterility.
Abstract: A method for analyzing vanillylmandelic acid, homovanillic acid and creatinine by fast liquid chromatography, which comprises a step of introducing a test solution containing vanillylmandelic acid, homovanillic acid and creatinine to a cation exchange resin column and separating creatinine from vanillylmandelic acid and homovanillic acid; a step of separating by a separation column vanillylmandelic acid and homovanillic acid in the test solution from which creatinine has been separated, and a step of detecting each component.
Abstract: An analyzing method of an Inductively-Coupled Radio Frequency Plasma (ICP) apparatus including a switch valve means for switching the flow of a sample which comprises the steps of: first switching the switch valve to the side of a plasma torch only during an ICP analyzing time; first supplying an induction coil a first radio frequency electric power and the plasma torch first volume of gas to cause plasma; analyzing the plasma; second switching the switch valve to an exit side of the sample during the times except for the ICP analyzing time; and second supplying the induction coil a second radio frequency electric power and the plasma torch second volume of gas to keep pilot light plasma, and an apparatus for use in such method; whereby the plasma is maintained at a condition of a pilot light except for analyzing, and a running cost is reduced.
Abstract: A method and/or system for rapidly determining the average composition and characteristics of a hydrocarbon mixture comprising thermally cracking the mixture to form a gaseous product, measuring the ratios or proportions of the individual components in the gaseous product, and comparing the ratios of the components present in the gaseous products with a known property of the hydrocarbon feed mixture and obtaining the average composition and intrinsic properties of the hydrocarbon feed.
Abstract: An improved process and an improved composite bearing material produced thereby comprising a hard metal backing strip having leaded-bronze bearing lining tenaciously bonded to at least one face surface thereof and wherein the bearing lining is characterized by having the lead constituent thereof substantially uniformly distributed throughout the lining matrix in the form of extremely fine-sized particles providing improved operating characteristics to the bearing materials fabricated therefrom.
Abstract: The invention is directed to a colorimetric gas measuring device with an indicator path which is accessible for the gas to be detected via at least one inlet opening and which, however, is otherwise closed off with respect to the ambient. The colorimetric gas measuring device is improved so that the measuring time is extended and the sensitivity increased while at the same time providing a space-saving configuration. The gas measuring device is small and convenient to handle and can be carried on the person. For this purpose, the indicator paths are configured so as to extend in circuitous manner.
Abstract: A method and apparatus for measuring a lipid peroxide, in which a sample containing lipids is subjected to a liquid chromatography to separate the lipids into lipid classes. The lipid classes are brought into contact with a luminescent reagent which specifically reacts with a lipid hydroperoxide contained in the lipid classes to generate a light in an amount corresponding to a content of the hydroperoxide. The light is optically detected by a photodetector.