Patents Examined by T. J. Wallen
  • Patent number: 4846826
    Abstract: A method is disclosed for treating an ischemic condition. The method comprises coadministering topically and internally a vasodilator to a patient having the condition for treating the condition.
    Type: Grant
    Filed: November 21, 1986
    Date of Patent: July 11, 1989
    Assignee: Alza Corporation
    Inventors: Jane Shaw, Robert M. Gale
  • Patent number: 4847204
    Abstract: Disclosed are a calibrator composition and method of producing and using the same in the analysis of blood of a particular species. From whole blood of the particular species, a solution is derived with which semi- and fully-automated particle counters can be calibrated to count cells in the size range appropriate for the particular species.
    Type: Grant
    Filed: July 16, 1987
    Date of Patent: July 11, 1989
    Assignee: Southeast Vetlab, Inc.
    Inventors: Barry T. Mitzner, Colin F. Aldersley
  • Patent number: 4844867
    Abstract: A colorimetric detector such as a gas dosimeter, contains a strip-like carrier with a detection reagent in a transparent housing that can be opened at least at one end thereof. The detector is expanded in terms of its use to such reagent systems in which the pigment formed diffuses beyond the reaction zone. For this purpose, the detection reagent is provided such that it is contained in impregnated tabs arranged in a row on the carrier.
    Type: Grant
    Filed: May 20, 1987
    Date of Patent: July 4, 1989
    Assignee: Dragerwerk Aktiengesellschaft
    Inventor: Wolfgang Bather
  • Patent number: 4845040
    Abstract: A method and apparatus are described for quantitatively determining the different forms of sulphur present in a solid matrix, e.g. coal. The novel method comprises intimately mixing finely divided coal with a finely divided solid diluent material, e.g. silica, which is inert to sulphur under reaction conditions. This mixed sample is then burned within a confined combustion zone at a predetermined elevated temperature and the combustion gases from the combustion chamber are continuously removed. These gases are passed through an infrared analyzer which continuously monitors the intensity of the infrared spectra for sulphur oxycompounds in the combustion gases. The infrared intensity is measured as a function of evolution time of sulphur oxycompound from the sample to obtain peaks in an infrared intensity-time pattern indicative of different forms of sulphur.
    Type: Grant
    Filed: November 13, 1987
    Date of Patent: July 4, 1989
    Assignee: Canadian Patents and Development Limited/Societe Canadienne Des Brevets Et D'Exploitation Limitee
    Inventors: Kwang S. Moon, Louis L. Sirois
  • Patent number: 4843013
    Abstract: This invention discloses a multiple control standard for the use in the quality assurance of blood analysis instrumentation systems. The liquid control standard is able to act as a control standard for blood gas instrumentation systems measuring pH, pCO2 and pO.sub.2 of blood, as a control standard for a co-oximeter measuring the amount of total hemoglobin present in the blood and the relative amounts of other hemoglobin fractions present in the blood, and as a liquid control standard for ion selective electrode instrumentation systems for the measuring of electrolytes such as Na, K, Li and Ca ions in the blood.
    Type: Grant
    Filed: March 2, 1988
    Date of Patent: June 27, 1989
    Assignee: Bionostics, Incorporated
    Inventor: Ching Chiang
  • Patent number: 4840911
    Abstract: A method of simulating a positive response by volatile organophosphorus ers to an ionization detector system which comprises forwarding to the ionization detector system a gaseous stream comprising water vapor and a di(lower alkyl) sulfoxide or a cyclic sulfoxide represented by the formula I: ##STR1## wherein R is hydrogen or a lower alkyl group, in an amount sufficient to elicit a positive response by the ionization detector system.
    Type: Grant
    Filed: May 28, 1987
    Date of Patent: June 20, 1989
    Assignee: The United States of America as represented by the Secretary of the Army
    Inventors: Joseph Epstein, John A. Parsons, Frank Block
  • Patent number: 4840904
    Abstract: A process for recovering cellulase from the hydrolysis of cellulose, and reusing it in subsequent hydrolyois procedures. The process utilizes a commercial adsorbent that efficiently removes cellulase from reaction products which can be easily removed by simple decantation.
    Type: Grant
    Filed: September 18, 1987
    Date of Patent: June 20, 1989
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventor: Jonathan Woodward
  • Patent number: 4839294
    Abstract: This invention relates to an assay useful for the evaluation of the lipid content of a biological fluid and its content in aqueous dispersion. The assay of the invention utilizes a dye-detergent complex which when solubilized by an aqueous dispersion of lipid-containing fluid sample, exhibits a characteristic color. The invention also provides for the use of the assay in the evaluation of the lipid content of a fluid, particularly amniotic fluid, which evaluation is useful for the prediction of Respiratory Distress Syndrome in newborns.
    Type: Grant
    Filed: August 24, 1987
    Date of Patent: June 13, 1989
    Assignee: Health Research Inc.
    Inventors: Rami Almog, Carol Anderson-Samsonoff, Donald S. Berns
  • Patent number: 4839287
    Abstract: A process is provided for the rapid transesterification of triglycerides with fatty acids in the presence of lipase enzyme, using an aqueous microemulsion reaction medium comprising a hydrophobic component, a surface-active component, and water.
    Type: Grant
    Filed: March 10, 1987
    Date of Patent: June 13, 1989
    Assignee: Berol Kemi AB
    Inventors: Krister Holmberg, Eva Osterberg
  • Patent number: 4836941
    Abstract: A clear brine fluid composition for use in servicing wells in the oil and gas industry comprising a solution of a zinc halide and a calcium halide in water having a density lying in the range of about 15 to about 22 ppg, a measured alkalinity lying in the range of about 0 up to about 1 normal and a measured zinc to calcium mole ratio lying in the range of about 1 to about 3.
    Type: Grant
    Filed: January 29, 1986
    Date of Patent: June 6, 1989
    Assignee: The Dow Chemical Company
    Inventor: Robert C. Thomas
  • Patent number: 4836904
    Abstract: An electrode has a graphite surface at least part of which is an edge-plane graphite surface to which Cr(III) complexes are attached by surface C--O groups. The graphite can be polished pyrolytic graphite. The complex coverage can be 5-20%. The complex may comprise proteins, enzyme substrates, specific binding agents, intermediate metabolites or the like, e.g. the protein plastocyanin, so that direct unmediated electrochemistry is possible at the electrode.
    Type: Grant
    Filed: March 13, 1986
    Date of Patent: June 6, 1989
    Assignee: Medisense, Inc.
    Inventors: Frazer A. Armstrong, Brian N. Oliver, Hugh A. O. Hill
  • Patent number: 4837374
    Abstract: A microreactor is described which is especially designed to analyze small solid samples, such as thin film catalyst. It includes (a) a horizontal tubular reaction vessel for receiving an article for testing, one end of the vessel being closed and the other end being connected to a ball valve end flange, (b) a horizontal shelf within the reaction vessel adapted to receive and support the article for testing, (c) gas inlet means for introducing gas into the vessel, (d) gas outlet means for removing gas from the vessel, (e) sensing means for sensing the temperature within the reaction vessel, (f) means disposed outwardly of the vessel and in heat-conductive relation to the outer surface thereof for heating the vessel, and (g) releaseable gripper means for delivering the article for testing through the ball valve and into the reaction vessel and for releasing the article onto the shelf.
    Type: Grant
    Filed: June 1, 1987
    Date of Patent: June 6, 1989
    Inventors: James R. Brown, Leighton L. Coatsworth, Irold S. Schmidt
  • Patent number: 4837163
    Abstract: The invention provides a simple, non-invasive method of screening malignant hyperthermia using a few milliliters of blood drawn from an individual into an acid-citrate anti-coagulant. When blood preservation is not needed, the blood specimen is stored for several hours at room temperature, after which a small amount of blood is taken into a cuvette with the optical path of 0.1 mm. Then, by measuring optical densities at wavelengths of 542 and 578 nm, the susceptibility for malignant hyperthermia can be determined. When a blood specimen has to be shipped to a distant screening center, the specimen can be stored in a styroform container at 0.degree.-4.degree. C. with either wet ice or artificial coolant and delivered by an express carrier service. Upon arrival, optical measurement is done in a similar fashion.
    Type: Grant
    Filed: October 2, 1987
    Date of Patent: June 6, 1989
    Inventor: Tsuyoshi Ohnishi
  • Patent number: 4828799
    Abstract: A method for the determination of the drug or other analyte content and concentration in bodily fluids that are directly injected in a micellar chromatographic column. Various embodiments of kits are also disclosed.
    Type: Grant
    Filed: June 26, 1985
    Date of Patent: May 9, 1989
    Assignee: Research Corporation
    Inventors: Linda J. C. Love, Robert Weinberger
  • Patent number: 4826770
    Abstract: Coated carbon composite parts to be tested for oxidation resistance are heated in a closed oven filled with an oxidizing atmosphere. During the heat cycle the carbon dioxide content of the oven atmosphere is measured by an analyzer such as a gas chromatograph. These measurements on the amount of CO.sub.2 emitted by the part provide information on the onset of oxidative failure. It forms a nondestructive test when detection of excessive carbon dioxide concentration is used to reduce the temperature and flood the oven with inert gas so the part may be saved and reprocessed. This technique can be combined with conventional weight measurements before and after oxidation to identify the part constituent, carbon composite or protective coating, that failed.
    Type: Grant
    Filed: September 24, 1987
    Date of Patent: May 2, 1989
    Assignee: General Electric Company
    Inventor: Michael K. Cueman
  • Patent number: 4823701
    Abstract: A multipoint initiation system for an explosive including a stripline head and a plurality of detonators fixed to the head at predetermined locations. The head and detonators are embedded in the explosive without a mechanical safe-arm device. Electrical connections in the head provide for independent detonation of the detonators.
    Type: Grant
    Filed: April 27, 1987
    Date of Patent: April 25, 1989
    Assignee: The Boeing Company
    Inventor: Earl E. Wilhelm
  • Patent number: 4822344
    Abstract: A variable infusion device for administering liquids parenterally to a patient is formed of inexpensive plastic members. The device includes an elongated passage defined between two members of the device which are bonded to one another. A third member is movable relative to the first and second members to change the length of the elongated passage through which liquid flows thereby changing the flow rate of the liquid through the device. The liquid flow rates to the patient can be incrementally adjusted over a wide range of flow rates. Settings also include a low flow rate for merely keeping the patient's vein open.
    Type: Grant
    Filed: December 5, 1986
    Date of Patent: April 18, 1989
    Assignee: Sta-Set Corp.
    Inventor: Matthew O'Boyle
  • Patent number: 4818501
    Abstract: A machine for sterilizing lipstick has a carriage which moves on a bench and holds and rotates the lipstick bar in front of a bank of Bunsen burners. The carriage rotates the lipstick in front of the Bunsen burners to sterilize and smooth the exterior of the lipstick bar. The carriage prevents the lipstick from rotating when the lipstick bar is not in front of the Bunsen burners.
    Type: Grant
    Filed: June 25, 1987
    Date of Patent: April 4, 1989
    Inventor: Jacinto Pruneda-Caridad
  • Patent number: 4816226
    Abstract: An analytical system is disclosed employing dual valve injector sampling and suitable for continuous flow injection analysis employing extraction of a liquid sample with an immiscible liquid solvent for a component of said sample liquid.
    Type: Grant
    Filed: December 30, 1987
    Date of Patent: March 28, 1989
    Assignee: Shell Oil Company
    Inventors: Jeffrey W. Jordan, Don C. Olson
  • Patent number: 4816410
    Abstract: A control slide for use in an immunoassay having a section of a cell pellet retained on the slide in a stable and substantially permanent formation which can be stored at room temperature. Further, the invention includes the method of making the control slide.
    Type: Grant
    Filed: October 29, 1986
    Date of Patent: March 28, 1989
    Assignee: Coulter Corporation
    Inventors: Stephen F. Healy, Jr., Michael L. Rice, Martin L. Golick