Patents Examined by Taina D Matos Negron
  • Patent number: 8592426
    Abstract: The invention provides novel compounds having the general formula (I) wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, A1, A2 and n are as described herein, compositions including the compounds and methods of using the compounds.
    Type: Grant
    Filed: January 17, 2012
    Date of Patent: November 26, 2013
    Assignee: Hoffmann—La Roche Inc.
    Inventors: Johannes Aebi, Alfred Binggeli, Cornelia Hertel, Anish Ashok Konkar, Holger Kuehne, Bernd Kuhn, Hans P. Maerki, Haiyan Wang
  • Patent number: 8574552
    Abstract: Disclosed is a pharmaceutical composition in the form of a tablet suitable for dissolution in the buccal cavity, said composition comprising i) an effective amount of a narcotic active ingredient, and ii) a pharmaceutically acceptable amine having a pK of about 8 or greater, wherein the molar ratio of amine:active ingredient is at least about 5:1.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: November 5, 2013
    Assignee: Alpex Pharma S.A.
    Inventors: Federico Stroppolo, Shahbaz Ardalan