Abstract: An injector including at least one fluid reservoir having a needle, a surface attached to skin and coupled to the fluid reservoir by at least a first joint and a second joint at least a portion of one of the joints being slidable or having interlocking arms. At least a portion of a path of translation of a slidable portion of the first joint and a portion of a path of translation of the second joint are angled in respect to each another.

Abstract: A medical instrument includes a handle, a trocar in communication with the handle, and a cannula in communication with the trocar and the handle. The cannula is engaged (locked) with the handle when linearly displaced proximally towards the handle and, the cannula is disengaged (unlocked) from the handle when linearly displaced distally away from the handle. The cannula is linearly reciprocated, between the locked position and the unlocked position, along a linear travel path defined parallel to a longitudinal axis of the trocar such that the cannula is prohibited and permitted to articulate about the longitudinal axis of the trocar, and relative to the handle, respectively. Advantageously, the cannula is locked and unlocked from the trocar by without requiring an external force exerted generally transverse to trocar and/or cannula—thereby permitting a user to lock/unlock the cannula, relative to the trocar, with one hand.

Abstract: The accessory (110) for an inhaler (100) is adapted to be removably assembled on a casing (101) of the inhaler (100), and comprises: an acceleration sensor (112), an optical type proximity sensor (113), an electronic circuitry (114) electrically connected to the acceleration sensor (112) and to the proximity sensor (113); the electronic circuitry (114) in combination with the acceleration sensor (112) and the proximity sensor (113) is adapted to detect a drug administration process; the electronic circuitry (114) in combination with the acceleration sensor (112) is adapted to detect an inhalation flow inside said inhaler (100).

Abstract: A syringe includes a dosage setter operatively coupled to a plunger rod and comprising a rotatable body that comprises a set of one or more stops for engaging the set of one or more protrusions of the plunger rod depending on at least a rotational position of the set of one or more stops relative to the set of one or more protrusions, wherein a first rotational adjustment associated with the dosage setter is configured to set a first dosage increment by adjusting a relative axial position between the rotatable body and the plunger rod, and a second rotational adjustment associated with the dosage setting assembly is configured to set a second dosage increment that is larger than the first dosage increment by adjusting a relative rotational alignment between the set of one or more stops and the set of one or more protrusions.

Abstract: A device for repetitive needleless injection including a handheld unit having at least a cell fillable with a liquid, and a propulsion mechanism to apply a sequence of pressure pulses to the liquid to eject a micro-jet of the liquid from the cell via an orifice with a velocity that is sufficient to enable the micro-jet to penetrate into the surface; a reservoir that is connected to the cell by a conduit to enable the liquid to flow from the reservoir to the cell; a controller that is configured to operate the propulsion mechanism repeatedly; and a unidirectional valve to enable flow of the liquid from the reservoir to the cell and to prevent backflow. The propulsion mechanism includes an impulse generator configured to displace an actuation surface to generate the pulse; a plunger to transmit the pulse to the cell, and a restoration mechanism to retract the plunger.

Abstract: The present invention concerns an apparatus (1) for measuring and recording the remaining quantity of medicament in a medicament dosing device (2). The apparatus (1) has a location where the medicament dosing device (2) can be inserted. Combined with that location the apparatus (1) has equipment for measuring and analysing. The apparatus is characterised in that this equipment for measuring and analysing comprises a contact image sensor (3) combined with that location for the medicament dosing device, and a software in connection with the contact image sensor. In addition the object of this invention is the corresponding method for measuring and recording the remaining quantity of medicament in a medicament dosing device (2).

Abstract: In some embodiments, a delivery device includes a device actuator and a cannula portion through which a therapeutic substance is ejected. The cannula portion includes an outer shaft, a needle that is configured to move through the outer shaft, and a plunger that is configured to move through the needle, forming a positive displacement arrangement.

Abstract: An injection system, including an injector having a dispensing mechanism configured to dispense a medicament, and a ready-to-use indicator. The ready-to-use indicator includes a controller configured to interact with the ready-to-use indicator and an audio and/or visual indicator, a temperature sensor, and a temperature analog having similar thermodynamic properties of the medicament. The temperature sensor is configured to detect a temperature of the temperature analog which represents the dynamic temperature of medicament as the medicament is heated or cooled. The temperature sensor is configured to communicate the detected temperature to the controller and to alert the controller when a preset temperature is reached. The ready-to-use indicator is configured to alert a user when the preset temperature is reached, signifying the medicament is thermally ready to be delivered by the dispensing mechanism. The audio and/or visual indicator is configured to display indicate one or more notifications to the user.

Abstract: An insertion set system includes a base configured to be secured to a patient, and a flexible tubing on the base. The flexible tubing has a distal end portion forming a cannula to be inserted into the patient. An inserter having a needle is received by the base. The needle has a channel in which the distal end portion of the flexible tubing is received. The needle is able to slide relative to the flexible tubing, to selectively withdraw the needle off of the distal end portion of the flexible tubing. The base may include a passage for fluid flow arranged transverse to the axial dimension of the distal end portion of the flexible tubing.

Abstract: A multiple pen needle or syringe needle storage and dispensing system where a plurality of needle devices such as pen needles including a cover can be disposed on strip, where the strip serves a seal for multiple needle devices. Each needle device can be peeled off the strip unsealed for immediate use for example in an injections device, or separated from the strip sealed for later use.

Abstract: An incremental syringe configured for displacement of fluid, such as medicaments is disclosed. The syringe may comprise detents on the syringe plunger configured to provide tactile feedback, audible feedback, or both, for discrete units of fluid aspirated or injected to or from the syringe. In some embodiments, a second set of detents is included, and in some embodiments a third set of detents is included.

Abstract: A method of delivering a catheter to a location of interest in the vasculature, the method including positioning a self-expanding sheath within a lumen of the catheter; advancing the catheter and the self-expanding sheath in tandem over a guidewire; and distally moving a distal end of the self-expanding sheath out from the lumen of the catheter thereby causing the self-expanding sheath to move from a collapsed state within the catheter to an expanded state outside the catheter, wherein when the self-expanding sheath is in the expanded state both the self-expanding sheath and the catheter are distally advanceable in tandem.

Abstract: The present disclosure relates to medicament injection devices. An injection device includes: a movable dosage programming component comprising a rotary encoder system having a predefined angular periodicity, a sensor arrangement including a first optical sensor configured to detect movement of the movable dosage programming component relative to the sensor arrangement during dosing of a medicament, wherein the first optical sensor is configured to operate in a strobe-sampling mode at a first frequency, a second optical sensor configured to detect movement of the rotary encoder system relative to the second optical sensor wherein the second optical sensor is configured to operate in a strobe-sampling mode at a second frequency lower than the first frequency, and a processor arrangement configured to, based on the detected movement, determine a medicament dosage administered by the injection device.

Abstract: A drive assembly includes a drive ribbon that can be retracted and extended. The retracted ribbon defines a spiral and the extended ribbon defines a helix. The drive ribbon is incrementally moveable between the retracted spiral configuration and extended helical configuration to move a piston within a container. A medical delivery device for advancing a piston in a medicament container to expel a medicament can include such drive assembly.

Abstract: Drug delivery safety devices having trigger activation systems activated by pressure against the skin of a patient and which automatically shield the needle after withdrawing the needle from the skin of the patient.

Abstract: An obturator assembly includes an obturator positionable within a lumen of a device and movable within the lumen between a first position and a second position. The obturator includes a distal tip portion, wherein, with the obturator in the first position, the distal tip portion limits fluid communication through the lumen and, with the obturator in the second position, the distal tip portion provides fluid communication through the lumen.

Abstract: An over-actuated system [304], such as a catheter, having shape memory alloy (SMA) hysteretic wire actuators is controlled using a controller [300, 302] that generates a control signal [310] based on a temperature model that takes into account physical limitations of the SMA hysteretic wire actuators, and based on a hysteresis model (e.g., the Duhem model) that describes hysteresis behavior of the SMA hysteretic wire actuators. The controller preferably includes a feedback controller [302] and a reference governor [300] that generates a smart reference signal [308] from a reference signal [306] representing a desired value of an output of the system. The smart reference signal preferably minimizes an error between the reference signal and an achievable output, and the control signal preferably is generated based on the smart reference signal.

Abstract: To prevent accidental needle stick injuries, a syringe has a plunger configured to pull the syringe into the syringe barrel after clinical use. The syringe has an additional safety feature that restricts subsequent movement of the plunger. After the needle has been retracted in its entirety within the barrel of the syringe, movement of the plunger is restricted by a two-part locking mechanism, a notch on the plunger and a T-shaped slot on the barrel with a one-way catch section to prevent the needle tip from being pushed accidentally through the barrel wall.

Abstract: A bi-directional steerable catheter adapted for delivery into a patient's vasculature. The pull wires which are used to tension the deflectable segment of the steerable catheter are wound in parallel around the axis of the steerable catheter on opposite sides of the steerable catheter.

Abstract: A catheter assembly (10) comprises a catheter (22), a needle (12) having a sharp distal tip disposed in the catheter (22), a catheter hub (14) housing the catheter (22) and the needle (12), the catheter hub (14) having a collar (34) including a notch (36), a needle shield (20) connected to the catheter hub (14) when the needle (12) is in a first position, and a clip (40) disposed in the needle shield (20) that cooperates with the needle (12), wherein the clip (40) engages the catheter hub (14) in the first position of the needle (12), and the clip (40) disengages the catheter hub (14) via the notch (36) when the needle (12) is retracted to a second position to enclose at least a portion of the needle (12). The clip (40) is mounted in the outer housing (38) of the needle shield (20) via a spade (66) having an outer wall (70) exposed to the outside of the needle shield (20), in order to reduce the overall width of the needle shield (20).