Abstract: A system, method and computer program product to determine radiation dose from radionuclides used to treat a patient in need thereof. The present invention allows users to visualize and understand the impact of radionuclide choice, distribution of activity in the cell, distribution of activity among the cells, cell dimensions, cell separation distance, cluster size, and radiobiological response parameters on the capacity to kill populations of cells. All of these parameters can play a substantial role in determining the surviving fraction of cells. Accordingly, this system, method and computer program product can assist in designing treatment plans for therapeutic radiopharmaceuticals suited to individual needs.

Abstract: A method of sizing a cavity to fit an organ is disclosed. The method may include inserting the organ into the cavity. The method may also include inserting a support member into the cavity and inserting a substance into the cavity or the support member. The support member and the substance may at least partially fill a void space in the cavity after the organ is inserted therein.

Abstract: A percutaneous implant for reducing the risk of post-implant infection by reducing the likelihood of epidermal down-growth between the dermis of the skin and the implant. In one example, the implant comprises a barrier member between the epidermis and the dermis about the implant. In another example, a barrier is provided by removing a portion of the epidermis from the dermis about the implant.

Abstract: A device for generating sensory stimuli, corresponding to sensory stimuli emanating from a reference person, for a child comprises a receiving unit for receiving a data stream from a device for acquiring sensory stimuli, emanating from a reference person, and a transducer unit, which is coupled to the receiving unit and is controllable by the data stream. The transducer unit generates at least either body-borne sound, which corresponds to the heart sounds, described by the data stream, of the reference person, or movements, which correspond to the movements, described by the data stream, of the reference person, or airborne sound, which corresponds to the airborne sound generated by the reference person and is described by the data stream.

Abstract: A totally implantable method for occluding the urethra or bladder neck utilizing an occlusive cuff connected to a control mechanism via a conduit tube. The occlusive cuff is reversibly changed from an activated (occlusive condition) to a deactivated (non-occlusive) condition by depressing a deactivation button contained within a resilient, elastomeric sheath surrounding the control mechanism. The occlusive condition is once again obtained by depressing an activation button also situated within the resilient sheath. In the occlusive condition, a preset tension is applied to a flexible diaphragm through a tensioning suture by a constant force spring contained within the control mechanism. This tension is translated into an occlusive pressure applied to the urethra or bladder neck sufficient to prevent urinary leakage.

Abstract: A system for therapy may include a mask (200) for a patient having a frame, cushion, forehead support and a light (100). The mask is connectable to a respiratory treatment apparatus, such as a flow generator, to receive breathable gas for a respiratory therapy. The light may also be connected to the power system and/or control system of the apparatus. A light may also be included in a module, such as a docking station, for a respiratory treatment apparatus. The lights may be controlled by one or more processors, and may be responsive to detected conditions, to assist with therapy. For example, the light may be turned on at a predetermined time or may be synchronized with the patient's sleep state, to assist in waking up the patient or re-setting the patient's circadian rhythm. Other components, such as sound and aroma generators of the system, may also be controlled for such therapies.

Abstract: A prosthesis including an abutment, an operationally removable component including a coupling apparatus, and an adapter, wherein the abutment is connected to the adapter and the coupling apparatus of the operationally removable component is releasably coupled to the adapter.

Abstract: The idea concerns irradiation of a target volume (53), wherein intensities for target points (70) are determined which are sequentially approached by a beam, comprising the following steps: detecting a volume (63) to be protected, wherein a dose generated by irradiating a target volume (53) does not exceed a predetermined maximum value; determining intensities for target points (70) in such a way that within the volume (63) to be protected the generated dose does not exceed the predetermined maximum value, wherein a dose contribution data record is used for determining the intensities, which dose contribution data record comprises the dose generated at other spots (73) by directing the beam (10) on one of the target points (70) with a predetermined intensity.

Abstract: Methods and devices producing time varying magnetic field have therapeutic uses. The device contains a coil made of insulated wires, an energy storage device, an energy source and a switch. The coil is flexibly attached in a case. The device has at least one blower for cooling the coil. The methods and devices can be used in for example in physiotherapy, neuropsychiatric therapy, aesthetic therapy, urology or urogynecology.

Abstract: A urological device comprises a urological valve for location in the bladder of a patient and a valve support stem for location in the urethra of a patient. The valve has a normally closed configuration to prevent flow from the bladder and an open configuration for fluid flow through the valve. The valve is automatically movable from the closed configuration to the open configuration in response to a pre-set hydrodynamic pressure applied for a pre-set time. In one case the valve has a plurality of valve leaflets with a region of co-aption between the valve leaflets. In the normally closed configuration the valve leaflets are engaged at the region of co-aption and in the open configuration the leaflets are separated at the co-aption region for fluid flow through the valve.

Abstract: An incontinence treatment device and method of treating urinary incontinence in a person includes fabricating an artificial urethra to have a flow diameter formed inside of a circumferential wall and a closure device attached directly to a portion of an outer surface of the circumferential wall of the artificial urethra. The artificial urethra is sized to be spliced to a natural urethra for alignment of the flow diameter of the artificial urethra with a lumen of the natural urethra. A pump is provided for moving liquid out of a reservoir and into the closure device to push the outer surface of the circumferential wall into the flow diameter of the artificial urethra, which operates to close the flow diameter of the artificial urethra.

Abstract: A shoe-shaped magnetic coil system for the treatment of foot pain which has an electrical pulse generator and a magnetic coil system connected to the electrical pulse generator. The magnetic coil system is in the general shape of a shoe with the electric current pulses flowing through magnetic coils of the magnetic coil system being capable of creation of intense magnetic pulses within a patient's foot and ankle. The coil of wire is formed of coil sections having a smallest area in the region of the patient's toes with a generally increasing area of the coil sections as the ankle region is approached.

Abstract: Surgical procedures, kits and implants for alleviating human incontinence, and particularly providing improved methods and apparatus to secure a urethral sling (30) to pubic bone (24, 26) to support the urethra and alleviate incontinence are disclosed. Bone anchors (64) are driven into pubic bones with elongated bone anchor sutures (84) configured to be passed through openings of a urethral sling. Suture retainers are applied to the sutures to apply retentive force to the urethral sling to maintain the fixation of the urethral sling proximate to the pubic bone.

Abstract: Embodiments include a fiducial deployment system with a handle configured for actuation of same. A fiducial may include one or more protuberances configured to engage one or more slots in a needle of the system. The needle may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time. In certain embodiments, echogenic placement of fiducials may present certain advantages. The handle includes an actuation mechanism with a toothed rack and actuation member(s) configured for incrementally or otherwise controlledly deploying one or more fiducials at a time by advancing a stylet through and/or retracting the body of a slotted needle in which fiducials are disposed with a fiducial protrusion extending into the needle slot, which also includes retaining structures that do not impede the needle lumen.

Abstract: An apparatus (60) for use within a woman's urethra (9) for inhibiting urine outflow when her intra-abdominal pressure rises. The apparatus (60) includes a generally tubular device (50) having a proximal end and a distal end and defining a longitudinal axis. Device (50) comprises structure (5) that is constructed and arranged to define a longitudinal passageway (14) that extends entirely through the device (50) from the proximal end to the distal end. Structure (5) is further constructed and arranged to be altered via an increase in intra-abdominal pressure, from a first state in which the passageway (14) is open along its length and able to conduct urine to a second state in which the passageway (14a) is more restricted or is closed off, to inhibit the passage of urine.

Abstract: A patient safety system (PSS) (100) uses optical tracking in a linear accelerator treatment room to prevent gross setup errors. A patient (150) undergoes a computed tomography (CT) treatment-simulation scan while a CT ball bearing (BB) is on patient's surface. The CT BB is replaced with an infrared reflective marker (IRRM) (160) before radiotherapy treatment starts. Coordinates of the CT BB relative to an isocenter of the treatment room are used as reference for tracking. The coordinate system of an optical tracking system is converted to a coordinate system of the treatment room. The PSS evaluates setup accuracy for a radiotherapy session by comparing real-time position of the single IRRM determined by the optical tracking technology with a predicted reference position, and displays results on a graphical user interface. The PSS stops radiation when a deviation between real-time coordinates and predicted coordinates of the IRRM (160) exceeds a predefined threshold.

Abstract: An implantable component including an implantable body including a functional component of the implantable medical device, and implantable actuator positioning mechanism connected to and extending from the implantable body, the actuator positioning mechanism configured to removably receive an implantable actuator.

Abstract: An electrical system controlled, driven by and/or based on naturally occurring electrophysiological signals in a patient's body is used to produce useful electromagnetic fields for health applications and/or medical applications provided to the patient.

Abstract: Systems, methods, and devices relating to transcranial magnetic stimulation (TMS). A circuit having at least two inductors is used in a TMS device. A small inductor adjacent to the patient's head and a large inductor away from the patient is used. The inductors are coupled to the circuit using multiple semiconductor switching subsystems. The subsystems, when activated, couple the inductors to the circuit and the inductors act as a single inductance. When deactivated, the subsystems decouple the inductors from the circuit and each inductor individually recovers or dissipates/discharges energy stored within. Since each inductor dissipates energy separately from each other, a much shorter dissipation or recovery time is achieved in the inductor close to the patient's brain as compared to the larger inductor. While dissipating or discharging, the small inductor induces electric currents in the brain to thus achieve stimulation and elicit action potentials.

Abstract: Disclosed is an assembly or system and apparatus for applying pulsing electromagnetic field (PEMF) coils to the underside of an equine hoof. The PEMF coil is encased in an elastomer structure to form a “puck” that will protect the coils from moisture, dirt and damage from rough use. The coil, and preferably a puck containing the coil may suitably be placed on, in or under an elastomeric orthotic pad that is disposed in a suitable equine boot.