Abstract: In various embodiments, the present disclosure provides testers for detecting a bacterial infection and methods of production and uses thereof.
Abstract: A process for the manufacture of butanol, acetone and other renewable chemicals utilizes one or more of by-products of the manufacture of malt whisky, such as pot ale and spent lees, biomass substrates, such as paper, sludge from paper manufacture and spent grains from distillers and brewers, and diluents, such as water and spent liquid from other fermentations. The process includes treating a substrate to hydrolyze it and fermenting the treated. Also provided is a biofuel including butanol manufactured according to the process.
Type:
Grant
Filed:
June 26, 2019
Date of Patent:
June 29, 2021
Assignee:
Celtic Renewables Limited
Inventors:
Jane Samantha White, Kenneth Alexander Leiper, Martin Tangney, Sandra Messenger
Abstract: Provided herein are scaffold biomaterials comprising a decellularised plant or fungal tissue from which cellular materials and nucleic acids of the tissue are removed, the decellularised plant or fungal tissue comprising a cellulose- or chitin-based 3-dimensional porous structure. Methods for preparing such scaffold biomaterials, as well as uses thereof as an implantable scaffold for supporting animal cell growth, for promoting tissue regeneration, for promoting angiogenesis, for a tissue replacement procedure, and/or as a structural implant for cosmetic surgery are also provided. Therapeutic treatment and/or cosmetic methods employing such scaffolds are additionally described.
Type:
Grant
Filed:
February 10, 2017
Date of Patent:
June 29, 2021
Assignee:
University of Ottawa
Inventors:
Andrew Edward Pelling, Charles Michel Cuerrier, Daniel J. Modulevsky, Ryan Joseph Hickey
Abstract: Dietary supplements comprising one or more probiotic bacteria or probiotic yeast in an oil with calcium phosphate added are provided. The calcium phosphate substantially reduces clumping and/or settling of the probiotic in oil. Other additives, such as anti-oxidants and taste enhancers, may be added to the compositions.
Abstract: The invention relates to utilising red marine macroalgae to provide improvements in growth performance of livestock, particularly ruminant animals for red meat production, especially cattle, in pasture and feedlot farming systems. There is provided a method for improving the growth performance of a livestock animal in a farming system including: providing a red marine macroalgae to a farming system to enable consumption of the red marine macroalgae by a livestock animal in the farming system; thereby improving the growth performance of the livestock animal in the system.
Type:
Grant
Filed:
July 29, 2016
Date of Patent:
May 18, 2021
Assignees:
JAMES COOK UNIVERSITY, COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION, MEAT & LIVESTOCK AUSTRALIA LIMITED
Inventors:
Nigel William Tomkins, Rocky De Nys, Robert Douglas Kinley, Marie Elisabeth Magnusson, Lorenna Machado, Nicholas Andrew Paul
Abstract: A system and process is disclosed for adding pre-fermentation separated non-fermentables, e.g., fiber, germ/oil, and/or protein, to a post-fermentation stream in a corn (or similar carbohydrate-containing grain) dry milling process for making alcohol and/or other biofuels/biochemical. The process includes mixing grain particles with a liquid to produce a slurry having starch and non-fermentables. The slurry is subjected to liquefaction to convert the starch in the slurry to complex sugars and produce a liquefied stream including the complex sugars and non-fermentables. After liquefaction but prior to fermentation of simple sugars resulting from conversion of the complex sugars, the non-fermentables are separated out to define a non-fermentables portion and an aqueous solution including the complex and/or simple sugars. The simple sugars are fermented to provide a fermented stream. Then, the separated non-fermentables portion is reincorporated back into the process into a post-fermentation stream.
Abstract: The invention relates to the use of at least one bacterial phytase in combination with one or more protease(s) in animal feed for improving weight gain and/or Feed Conversion Ratio (FCR), wherein the phytase is administered in one or more of the following amounts (dosage ranges): 1,000 FYT/kg feed, 2,000 FYT/kg feed 3,000 FYT/kg feed and wherein the protease is administered in one of the following amounts (dosage ranges): 10,000 units/kg feed, 11,000, 12,000, 13,000, 14,000, 15,000, 16,000, 17,000, 18,000, 19,000, 20,000 units/kg feed.
Abstract: The invention relates to a method for triggering triacylglycerols (TAG) accumulation in microalgae comprising the step of contacting a source of exogenous nitroxide (NO) with said microalgae in their growth medium.
Type:
Grant
Filed:
January 27, 2017
Date of Patent:
April 13, 2021
Assignee:
Commissariat A L'Energie Atomique Et Aux Energies Alternatives
Abstract: Methods and compositions for removing precipitates or reducing the formation of precipitates generated in hematoxylin solutions. The methods and compositions feature cleaning solutions that feature chemical compounds that initiate processes including but not limited to acidification of the waste solution, chelation of metal ions in the waste solution, reduction reactions, oxidation reactions, and metal salt addition reactions.
Type:
Grant
Filed:
November 17, 2017
Date of Patent:
April 13, 2021
Assignee:
Ventana Medical Systems, Inc.
Inventors:
Edward E. Durrant, Henning Groll, Casey A. Kernag, Charles H. Weidner, Kenneth S. Weir
Abstract: A method of processing and storing biological cells includes introducing a flowable medium into a microfluidic device, the flowable medium including biological cells; sequestering one or more biological cells from the flowable medium in one or more isolation regions of the microfluidic device; and freezing the microfluidic device including the one or more biological cells sequestered therein.
Type:
Grant
Filed:
April 22, 2016
Date of Patent:
April 13, 2021
Assignee:
Berkeley Lights, Inc.
Inventors:
Mark P. White, Kevin T. Chapman, Andrew W. McFarland, Eric D. Hobbs, Randall D. Lowe, Jr.
Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.
Type:
Grant
Filed:
August 30, 2019
Date of Patent:
March 23, 2021
Assignee:
Carnegie Mellon University
Inventors:
Alan J. Russell, Hironobu Murata, Chad S. Cummings, Richard R. Koepsel
Abstract: Solutions and methods are disclosed for the extraction and quantification of cellulose derived from cellulosic biomass samples. Improved extraction yields and selectivities are provided through the use of an extraction solvent mixture comprising an aprotic solvent such as DMSO, a quaternary ammonium salt such as TBAF, and an quaternary ammonium base such as TBAOH. The extracted cellulose can be optionally precipitated using disclosed precipitation solutions to further improve cellulose purity. Extracted cellulose can be measured by hydrolyzing the cellulose to glucose or cellobiose, or by using disclosed spectrophotometric assays of cellulose-salt complexes.
Abstract: Embodiments of the invention provide at least one polymer covalently conjugated to an esterase. The at least one polymer includes a plurality of oxime functional groups.
Type:
Grant
Filed:
August 30, 2019
Date of Patent:
March 16, 2021
Assignee:
Carnegie Mellon University
Inventors:
Alan J. Russell, Hironobu Murata, Chad S. Cummings, Richard R. Koepsel
Abstract: Disclosed herein are methods of increasing nitrogen fixation in a non-leguminous plant. The methods can comprise exposing the plant to a plurality of bacteria. Each member of the plurality comprises one or more genetic variations introduced into one or more genes or non-coding polynucleotides of the bacteria's nitrogen fixation or assimilation genetic regulatory network, such that the bacteria are capable of fixing atmospheric nitrogen in the presence of exogenous nitrogen. The bacteria are not intergeneric microorganisms. Additionally, the bacteria, in planta, produce 1% or more of the fixed nitrogen in the plant.
Abstract: Presented herein are methods for the treatment of oncological disorders by the co-administration of CoQ10 formulations and chemotherapeutic agents and/or surgery. The CoQ10 formulations may be at least one of intravenous, topical, or by inhalation. The chemotherapeutic agents may be at least one of antimetabolites or anthracyclines. Co-administration of the CoQ10 formulations may be prior to, concurrent or substantially concurrent with, intermittent with or subsequent to the administration of the chemotherapy.
Abstract: Provided herein a re composition and process for using an electrochemical device for the reduction of the oxidized state of phosphorylated or non-phosphorylated nicotinamide adenine dinucleotide to the reduced state in which unwanted products of the electrochemical reduction are recovered as the oxidized state of the phosphorylated or non-phosphorylated nicotinamide adenine dinucleotide and returned to the electrochemical device for reduction.
Type:
Grant
Filed:
March 14, 2017
Date of Patent:
February 23, 2021
Assignee:
Biocheminsights, Inc.
Inventors:
Clifford S. Morrison, William B. Armiger, David R. Dodds, Mattheos Koffas
Abstract: Provided is GDH with increased applicability to glucose sensors. A composition contains FADGDH, wherein when 0.1 mL of the composition is added to 2.9 mL of a solution containing 10 mM of trehalose and 1 mmol/L of potassium ferricyanide to give a glucose dehydrogenase activity of 500 U/mL and incubated at 37° C., the decrease in absorbance at 405 nm resulting from reduction of the potassium ferricyanide is less than 20 mAbs per minute.
Abstract: Methods for detecting an analyte in a body fluid are described as well as devices and systems adapted for performing such methods. In embodiments of the method, a sample of body fluid is applied to a test element having at least one test field including at least one test material that is adapted to change at least one measurable property in the presence of the analyte. The test element further includes a capillary to guide the sample across said test field in a flow direction. The test element also includes first and second measurement locations offset from each other in the flow direction. The measurable property is measured in at least one first measurement location, providing at least one first measurement value, and it is measured in at least one second measurement location, providing at least one second measurement value.
Type:
Grant
Filed:
September 18, 2015
Date of Patent:
January 26, 2021
Assignee:
ROCHE DIABETES CARE, INC.
Inventors:
Joachim Hoenes, Christian Ringemann, Andreas Weller
Abstract: This invention relates to a process for producing lactic acid or its salts that can be performed easily, reduce complicated steps, and provide high lactic acid yield and high productivity, wherein said process comprising of the following steps: (a) cultivating thermotolerance Bacillus genus bacteria to obtain a seed culture; (b) increasing cell number of bacteria by inoculating the seed culture contained from step (a) into a fermenter containing an initial carbon source under an aerobic condition; (c) fermenting the seed culture obtained from step (b) in the fermenter under a microaerobic condition to obtain lactic acid or its salts; wherein the step (b) comprising at least one addition of the carbon source under any one of the following conditions, where are independent to each other, to increase a concentration of the carbon source: when the concentration of the carbon source in the fermenter reduces to 50 % or less comparing to the initial concentration.