Abstract: Every pulse wave, a constant volume control unit performs servo control while updating a servo gain such that a difference between an arterial volume shown by an arterial volume signal that is detected by an arterial volume detection circuit and a control target value of the servo control is less than a control deviation at which a rate of change of the arterial volume relative to a change in cuff pressure is deemed to be constant. Because the control deviation is the difference between the arterial volume shown by the arterial volume signal and the control target value, a blood pressure decision unit decides, as a blood pressure, the cuff pressure sequentially detected in a period during which servo control is performed, by correcting the cuff pressure using the control deviation and the rate of change deemed to be constant.

Abstract: Systems and methods for prediction and detection of circulatory shock using estimates or measurements of arterial blood pressure, heart rate, stroke volume, cardiac output, total peripheral resistance, cardiac ejection fraction, cardiac contractility and ventricular end-diastolic volume are provided. These estimates and measurements are used to determine a type of circulatory shock. In some embodiments, the type of circulatory shock is determined to be one of septic shock, hypovolemic shock, anaphylactic shock, hemorrhagic shock, and cardiogenic shock.

Abstract: A first sensor may be configured to measure a sensed amount of a physiological parameter and to generate a first signal based on the sensed amount of the physiological parameter measured by the first sensor. A second sensor may be configured to measure a temperature and to generate a second signal based on the temperate measured by the second sensor. A housing may have heat-generating electronics including a processor that may be configured to determine an overall amount of the physiological parameter based on the first signal generated from the first sensor and the second signal generated from the second sensor. The second sensor may be thermally insulated from the heat-generating electronics.

Abstract: The present invention relates to a device for evaluating condition on skin or hair. The device provides one extension supporting a hydration meter suitable for measuring hydration values in areas difficult to measure (e.g., skin in scalp area) and; a separate extension supporting a camera for capturing images of an area of skin or hair and transferring said image to computer. Data from these sources are evaluated and scored. The multiple data points are used to provide a highly targeted product best suited for each individual consumer.

Abstract: Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.

Abstract: A method for optimizing a gas conversion rate in a respiratory gas analyzer, more particularly for nitric oxide (NO) in the respiratory gas, and an associated device are disclosed.

Abstract: The invention provides a device for contacting a surface of a patient's body to determine a physiologic parameter in a measurement region of a tissue of the patient. The device typically comprises a sensor responsive to the physiologic parameter and a probe housing the sensor. The probe is constructed to allow the sensor to be secured at a sensing site adjacent to the measurement region, without disturbing the blood flow within the measurement region of the tissue. The device may also include a means for reducing interference in the sensing area. Preferably, the device further comprises an indicating means operably connected to the sensor for indicating an analyte quantity and/or concentration associated with the physiologic parameter.

Abstract: A breath tester and method for sampling the odor of an user's saliva. The tester includes an elongated testing surface having a closed end and an open end to collect the saliva. The user collects and traps the saliva on the elongated testing surface and smells the surface to self determine the presence of halitosis. In one embodiment, the tester has a handle mounted to one end of the elongated testing surface. The breath tester can be disposed in a hollow housing. The sampling of the saliva can be allowed to dry upon the elongated testing surface before smelling.

Abstract: Deployable antennas for in-body devices, such as implantable and ingestible devices, are provided. Aspects of the in-body deployable antennas of the invention include antennas configured to go from a first configuration to a second configuration following placement in a living body, e.g., via ingestion or implantation. Embodiments of the in-body devices are configured to emit a detectable signal upon contact with a target physiological site. Also provided are methods of making and using the devices of the invention.

Abstract: An acoustic physiological monitoring system and method wherein the usability for physiological monitoring of time segments of an acoustic signal recording body sounds is determined using frequency analysis. A time segment of the acoustic signal is filtered into a target portion in a target frequency band and a non-target portion in a non-target frequency band. Energies of the target portion and the non-target portion are computed. A usability indicator for the time segment is computed using the energies. The usability of the time segment is determined using the usability indicator. A physiological parameter estimate is selectively calculated using the time segment based on the usability of the time segment. Finally, information based on the physiological parameter estimate is outputted.

Abstract: A measurement device pressurizes two cuffs in a state in which the cuffs are attached to the distal side and the proximal side of the measurement device, respectively, calculates an AI value or the like based on a pulse wave detected from a change in cuff pressure on the distal side while pressurizing the two cuffs, and determines that avascularization on the distal side has been completed if the AI value or the like has converged. Once it is determined that avascularization has been completed, the cuff pressure on the distal side is fixed, and a pulse wave is detected from a change in cuff pressure on the proximal side in a state in which the distal side is avascularized.

Abstract: A handheld, conforming capacitive sensing apparatus configured to measure Sub-Epidermal Moisture (SEM) as a mean to detect and monitor the formation of pressure ulcers. The device incorporates an array of electrodes which are excited to measure and scan SEM in a programmable and multiplexed manner by a battery-less RF-powered chip. The scanning operation is initiated by an interrogator which excites a coil embedded in the apparatus and provides the needed energy burst to support the scanning/reading operation. Each electrode measures the equivalent sub-epidermal capacitance corresponding and representing the moisture content.

Abstract: The present disclosure relates to monitoring a characteristic respiration rate of a patient based at least in part on a suitable time period that either precedes or follows a triggering event, such as a clinician/patient interaction, where the triggering event may negatively impact the physiological parameter. In some embodiments, physiological parameter values falling between one or more pre-set thresholds may be used to derive the characteristic physiological parameter. In some embodiments, monitoring the respiration rate may provide additional information about the patient's status. In some embodiments, confidence measures may be associated with, or may be used to analyze features of the patient signal to derive information about, the characteristic respiration rate. The patient signal used to derive a patient's respiration rate may be of an oscillatory nature or may include oscillatory features that may be analyzed to derive a characteristic respiration rate.

Abstract: Systems, methods, and products for determining indicated blood pressure values and/or characterizing a condition of a patient. The systems, methods, and products are capable of determining indicated blood pressure values in a lower extremity of a patient using an oscillometric technique. An oscillometric signal obtained from the lower extremity of the patient is analyzed, and the patient may be classified into one of a plurality of diagnostic classes. Each diagnostic class may have an associated ratio value. Based on the diagnostic class into which the patient is classified, a selected lower extremity characteristic ratio may be selected. A lower extremity indicated blood pressure value may be obtained by oscillometric processing using the selected ratio. This lower extremity indicated blood pressure value may be used with an upper extremity indicated blood pressure value to perform an extremity blood pressure ratio (EBPR) examination.

Abstract: Provided is a method of selecting a stent for implantation in the circulatory system of a human being. The method comprises obtaining a blood sample from a patient who requires implantation of a stent and testing said blood sample to determine a platelet coagulability level. The determined platelet coagulability level of said blood sample is compared with a threshold level of blood platelet coagulability. A determined platelet coagulability level above said threshold level indicates that a risk of restenosis is relatively high. If the determined platelet coagulability level is below said threshold level, a bare metal stent is selected. If the determined platelet coagulability level is at or above said threshold level, a drug-eluting stent is selected.

Abstract: There is provided an apparatus for determining a heart pulse of a person, the apparatus comprising at least two detectors configured to detect a blood pulse optically from the blood circulation of the person and to be placed optically on the skin of the person such that the detection of the blood pulse by each of the at least two detectors is expected to take place in a known order, a processor configured to determine that the detection of the blood pulse is correct when the detection of the blood pulse by each of the at least two detectors takes place in the known order, and to determine the heart pulse of the person on the basis of the detected pulses that are determined as correct.

Abstract: A method and an apparatus for non-interfering blood pressure measurements, relates to an apparatus for continuously monitoring blood pressure for patients at home or at work. The apparatus includes an extra-corporal sensor for blood pressure determination with a flexible housing adapted to be attached to the body of a living being proximate to an artery, and an electronic circuit for wireless coupling to a remote transceiver in accordance with the blood pressure in the artery, the remote transceiver adapted for wireless coupling to the sensor for generation of a pressure signal in accordance with the blood pressure in the artery, and a processor connected to the remote transceiver for reception of the pressure signal and adapted to estimate systolic and diastolic pressure based on the signal.

Abstract: A battery-free electronic blood pressure measuring apparatus comprising a cuff (40), an airbag (22) to push air into the cuff (40), a power generation unit which has a generator (42) and an operating handle (28) coupled with the wall of the airbag (22) to generate electrical power, and a display device (44) to receive electrical power from the power generation unit, detect a blood pressure signal from the cuff (40), generate and display a blood pressure measurement. A method for electronically measuring blood pressure with a battery-free sphygmomanometer comprises pressing an airbag and a generator-driving structure attached to the airbag wall, which leads to electrical power generation and cuff inflation by the airbag at the same time, and measuring the blood pressure with the generated electrical power.

Abstract: A signal representing physiological information may include information related to respiration. A patient monitoring system may generate a plurality of autocorrelation sequences from the signal and combine the autocorrelation sequences to generate a combined autocorrelation sequence. The combined autocorrelation sequence may be analyzed to identify one or more peaks that may correspond to respiration information. Respiration information such as respiration rate may be determined based on the one or more peaks.

Abstract: A set of brain data representing a time series of neurophysiologic activity acquired by spatially distributed sensors arranged to detect neural signaling of a brain (such as by the use of magnetoencephalography) is obtained. The set of brain data is processed to obtain a dynamic brain model based on a set of statistically-independent temporal measures, such as partial cross correlations, among groupings of different time series within the set of brain data. The dynamic brain model represents interactions between neural populations of the brain occurring close in time, such as with zero lag, for example. The dynamic brain model can be analyzed to obtain the neurophysiologic assessment of the brain. Data processing techniques may be used to assess structural or neurochemical brain pathologies.