Abstract: A medical probe includes a shaft for navigation in a patient body, and first and second deflection mechanisms. The shaft ends with a flexible section and a spring, followed by a rigid distal tip having one or more medical devices coupled thereto. The first deflection mechanism is configured to deflect the flexible section relative to the shaft. The second deflection mechanism is configured to deflect the distal tip relative to the first flexible section by using the spring.

Abstract: Systems, devices, and methods for electroporation ablation therapy are disclosed, with the device including a set of splines coupled to a catheter for medical ablation therapy. Each spline of the set of splines may include a set of electrodes formed on that spline. The set of splines may be configured for translation to transition between a first configuration and a second configuration. The devices described herein may be used to form a lesion via ablation by irreversible electroporation.

Abstract: Systems, delivery devices, and methods to treat to ablate, damage, or otherwise affect tissue. The treatment systems are capable of delivering energy to nerve tissue in a target region such that at least a portion of the nerve tissue is replaced by scar tissue or otherwise altered to inhibit reinnervation in the target region.

Abstract: Disclosed is a working end of a surgical instrument for delivering heat energy to tissue and (RF) energy for cutting tissue of different modalities. The working end includes paired first and second metal jaw members movable between open and closed positions, with each jaw member defining a jaw body and jaw end-effecter for engaging and heating tissue for the sealing of the tissue or vessels, or welding and coagulation of the tissue and jaw structure capable of generating radiofrequency (RF) energy for cutting tissue. Jaw members contain a microwave emitter coupled to a microwave energy source, the emitter is located within the jaw end effecter, which effecter includes an insert made of a microwave energy absorbing material which converts microwave energy into the heat energy. Jaw members also contain electrodes located within the jaw effecter end coupled to a radiofrequency (RF) energy source for procedures including tissue cutting, etc.

Abstract: A chemical ablation therapy delivery system includes an expandable element, a guide tube attached to the expandable element, and a needle movably disposed within the guide tube.

Abstract: This treatment portion of a medical energy device treats a biological tissue by transferring energy to the biological tissue, in a state where the treatment portion is in contact with the biological tissue. The treatment portion of the medical energy device includes a main body portion and a covering film. The main body portion transfers energy to the biological tissue. The covering film contains silicone as a main component, and covers the surface of the main body portion. The silicone includes at least a D unit and a T unit. In the silicone, the molar ratio of silicon atoms forming the D unit with respect to all the silicon atoms is 40-99%. In the silicone, the molar ratio of methyl functional groups bonded to the silicon atoms with respect to all functional groups bonded to the silicon atoms is at least 60%.

Abstract: An apparatus for cooling an ablation probe includes a cassette receptacle configured to accept a cassette including a supply tube for supplying a coolant to the ablation probe. The apparatus also includes a pump head movably positioned proximate the cassette receptacle. The pump head is configured to move between a loading position and an operating position. The pump head includes one or more rollers configured to engage the supply tube of the cassette when the pump head is in the operating position. The apparatus also includes an actuator coupled to the pump head. The actuator is configured to move the pump head between the loading position and the operating position.

Abstract: A method for controlling an epicardial ablation procedure comprises (a) inserting an instrument port comprising an ablation tool, an optical camera and an optical light emitter into an epicardial cavity proximal to a target region; (b) providing optical light into said epicardial cavity through said optical light emitter to illuminate said target region; (c) obtaining a first image of said target region using said optical camera; (d) steering a tip of said ablation tool towards said target region; (e) applying an ablation energy to said target region using the ablation tool so as to form a lesion in or on said target region; (f) obtaining a second image of said target region using said optical camera; and (g) processing at least one of said first and second images in an image processor so as to determine a characteristic of said lesion.

Abstract: A catheter comprising a transducer located in an interior of a balloon, the transducer configured to transmit an acoustic signal at an operational frequency that provides an acoustic field with multiple lobes along a longitudinal axis of the transducer. Each of the lobes has a spatial intensity distribution at a surface of the balloon and parallel to a surface of the transducer which comprises a spatial intensity maximum and one or more reduced spatial acoustic intensity locations where the spatial intensity of the acoustic field of the transducer is 50% or less of a value of one of the spatial intensity maxima, where the reduced locations are between the spatial intensity maxima and adjacent to one another along the longitudinal axis of then transducer. The catheter further comprises at least an electrode configured to transmit an electromagnetic signal, the electrode being positioned on the balloon at one of the reduced spatial acoustic intensity locations of the transducer.

Abstract: Flexible instruments and associated systems and methods are disclosed herein. In some embodiments, a flexible instrument comprises an elongate device having an inner conductor, an outer conductor surrounding the inner conductor, and a dielectric layer insulating the inner conductor from the outer conductor. The flexible instrument further includes a recess formed in the outer conductor. An insert is positioned within the recess and about the inner conductor.

Abstract: Systems, methods, and instrumentalities are described herein for autonomous operation of a surgical device within a predefined boundary. A discrete signal associated with clamping control (e.g., closure of a clamping jaw) may be received by the surgical device. The discrete signal may be triggered by a healthcare professional or autonomously activated. The surgical device, in response to the discrete signal and based on an algorithm, may generate a continuous signal to cause a continuous application of force or deployment of an operation. The surgical device, based at least on a measurement associated with one of tissue, inrush current, or the distance between the smart energy device and the smart grasper may determine a safety adjustment associated with the operation of the surgical device.

Abstract: A tissue treatment system configured to ablate a tissue, the system comprising: (a) a clamp assembly comprising a first jaw mechanism and a second jaw mechanism configured to receive and compress a tissue therebetween; (b) a first electrode disposed on the first jaw mechanism and configured to contact the tissue; and (c) a second electrode disposed on the second jaw mechanism and configured to contact the tissue, where the first electrode and the second electrode are configured so that at least one of an ablation energy output of the first electrode and an ablation energy output of the second electrode is automatically adjusted to accommodate variable tissue thicknesses between the first electrode and the second electrode.

Abstract: An ablation catheter comprises a proximal portion, a distal portion extending from the proximal portion, the distal portion comprising a set of insulated lead segments each having a distal end; and a set of uninsulated electrode segments, wherein each electrode segment is connected to and extends from the distal ends of a pair of adjacent insulated lead segments, and wherein the distal portion is configured to form a compact first configuration for advancement within a sheath lumen into an endocardial space, and to transform to an expanded second configuration when advanced out of the sheath lumen.

Abstract: An electrode apparatus for nerve denervation or modulation in vivo includes a main body including a shaft; an electrode unit formed to be drawn out from one end of the shaft and configured to denervate or modulate at least some of nerves on a tube in the body; an electrode guide including a plurality of joint units and a wire connecting the plurality of joint units to each other and configured to guide the electrode unit; and a driving unit located inside the main body and configured to drive the joint units and the wire to protrude from the one end of the shaft. The driving unit drives the joint units in conjunction with the wire to have different displacements by using a gear ratio between two rack gears depending on a pitch circle diameter ratio between two pinion gears.

Abstract: The disclosure is directed to an electrosurgical generator comprising: an electromagnetic signal supply unit for generating electromagnetic, EM, energy to be conveyed along each of a plurality of channels. Each of the plurality of channels is arranged to convey electromagnetic energy at a different frequency. The electrosurgical generator further comprises an output port selectively connectable to each of the plurality of channels. The output port is connectable to an electrosurgical instrument for delivering the electromagnetic energy to biological tissue. The electrosurgical generator further comprises a tissue identification unit comprising a controller configured to: detect a signal indicative of a load impedance at the output port; determine a set of complex impedance values from the detected signals; identify a tissue type from the set of complex impedance values; and generate an output for communicating the identified tissue type to a user.

Abstract: A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Abstract: A method for treating patients who suffer from chronic rhinitis that is efficient and causes fewer adverse effects than known methods. This is achieved by using a handheld surgical instrument, more particularly an electrosurgical applicator, for treatment of hypertrophic nasal conchae and/or for submucosal treatment of the posterior nasal nerve (PNN) in order to reduce at least one cardinal symptom of chronic rhinitis.

Abstract: Aspects of the present disclosure are directed to, for example, a high-thermal-sensitivity ablation catheter tip with force measurement capability. More specifically, various aspects of the present disclosure are directed to improving the deformation consistency of the ablation catheter tip in response to various forces, and thereby improving force measurement accuracy of an ablation catheter system.

Abstract: A balloon aortic lithotripsy assembly for placement adjacent an aortic valve. The balloon aortic lithotripsy assembly includes multiple balloon chambers, a shell, and a shock wave generator. The balloon chambers are arranged to establish an open interior residing inboard of the balloon chambers. The shell is located around the balloon chambers. The shock wave generator can be situated on one or more of the balloon chambers, the shell, or both of the balloon chamber(s) and shell. In use, blood is free to travel through the open interior, and the shock wave generator can produce shock waves that are intended to impinge calcified tissues residing at the aortic valve.

Abstract: High-voltage pulses ablation systems and methods are used to ablate tissue and form lesions. A variety of different electrophysiology devices, such as catheters, surgical probes, and clamps, may be used to position one or more electrodes at a target location. Electrodes can be connected to power supply lines and, in some instances, the power to the electrodes can be controlled on an electrode-by-electrode basis. High-voltage pulse sequences provide a total amount of heating that is typically less than that which is observed with thermally-based radiofrequency energy ablation protocols.