Abstract: The fibrous polymeric material based on polyvinyl chloride contains at least one antiseptic mercury derivative distributed in its polymeric structure in the form of a substantially molecular and practically non-releasable dispersion.The preferred mercury derivatives have the following general formula: ##STR1## in which Y is H or HgX. If the concentration of the derivative is equal to at least 0.5% by weight, relative to the chlorofiber, the latter has a permanent antiseptic character.This material is obtained by incorporating the above-mentioned derivative into the collodion when the chlorofiber is spun.
Type:
Grant
Filed:
September 20, 1989
Date of Patent:
November 26, 1991
Assignees:
Institut Textile de France, Rhovyl
Inventors:
Michel Bourgeois, Roger Chatelin, Daniel Wattiez, Michel Sotton, Francois Belet, Georges Achard
Abstract: The invention relates to a transdermal therapeutic system for administering or applying active substances to the skin with a backing layer remote from the skin, an active substance depot, an active substance delivery control means controlling the delivery of the active substance through the system and a contact adhesive means for fixing the therapeutic system to the skin, in which the active substance depot is a multichamber system, in which discreet chambers contain one or more active substances.
Type:
Grant
Filed:
April 3, 1989
Date of Patent:
November 19, 1991
Assignee:
Lts Lohmann Therapie-Systeme GmbH & Co. KG
Abstract: A delivery system is disclosed for delivering a beneficial agent to an animal. The delivery system comprises a wall that surrounds a lumen, said wall comprising a composition that limits the passage of fluid into the system and a composition that permits the passage of fluid into the system. The lumen comprises a beneficial agent and an expandable member. The delivery system comprises an exit means for delivering the beneficial agent.
Type:
Grant
Filed:
April 23, 1990
Date of Patent:
October 22, 1991
Assignee:
Alza Corporation
Inventors:
Judy A. Magruder, James B. Eckenhoff, Richard Cortese, Jeremy C. Wright, John R. Peery
Abstract: Disclosed is a porous protein particle for delivering over a period of time an active ingredient impregnated therein, and methods of making and using the same. The protein particles have a median size less than about 50 microns. Active ingredient entrapped in the porous structure is gradually released from the protein particle.
Abstract: Method and compositions for enhancing the cutaneous penetration of topically or transdermally delivered pharmacologically active agents. The compositions include various urethane compounds as permeation enhancers, the urethane compounds formed from reaction of a monomeric organic diisocyanate with a hydroxy- or hydroxy/alkoxy-terminated linear alkylene or polyalkylene glycol or polyether.
Type:
Grant
Filed:
September 20, 1990
Date of Patent:
September 24, 1991
Assignee:
The Regents of the University of California
Inventors:
Samuel Chess, Jerry L. McCullough, Gerald D. Weinstein
Abstract: A controlled-release formulation of a pharmacologically active substance of poor aqueous solubility comprising sufficient granules to provide a predetermined dose or number of doses of the pharmacologically active substance, each of said granules comprising 100 parts of said pharmacologically active substance and usually from 20 to 400 parts of carbomer.The granules are optionally each provided with a coating covering substantially the whole surface thereof and comprising 100 parts of water insoluble but water swellable acrylic polymer and from 20 to 70 parts of a water soluble hydroxylated cellulose derivative, the weight of the underlying granule and the diameter of the coated granules being between 0.5 and 2.5 mm.A method for preparing the formulation is also provided.
Type:
Grant
Filed:
October 12, 1988
Date of Patent:
September 24, 1991
Inventors:
Brian W. Barry, Byran Arthur Mulley, Peter York
Abstract: Described is particulate halogen-containing material, e.g., calcium hypochlorite, containing from about 0.1 to about 10 weight percent of colorant-treated particulate inorganic water soluble salt, e.g., sodium chloride. The colorant used with the sodium chloride salt is resistant to oxidation by the halogen specie in the material and is water dispersible. The amount of colorant used is from about 0.01 to about 5 weight percent, based on the inorganic salt. Preferred are the water dispersible phthalocyanine colorants.
Type:
Grant
Filed:
June 30, 1988
Date of Patent:
September 17, 1991
Assignee:
PPG Industries, Inc.
Inventors:
Charles R. Wiedrich, Robert B. Simmons, Jonathan G. Lasch
Abstract: A pharmaceutical composition of sulbactam or pharmaceutically acceptable salts thereof and methampicillin or pharmaceutically acceptable salts thereof, in an amount of about 1-99% to 99-1% by weight. The pharamaceutical composition is effective for treating bacterial infections.
Abstract: Compositions containing certain indoles and quaternary ammonium salts are useful for imparting a tan to skin without prolonged exposure to the sun.
Type:
Grant
Filed:
November 22, 1989
Date of Patent:
September 17, 1991
Assignee:
Clairol Incorporated
Inventors:
Thomas M. Schultz, George Serban, Alexander C. Chan
Abstract: A non-conventional lipid particle formulation for the sustained release and delivery of steroids into deep lung is disclosed. The formulation provides prolonged release of the drug, improved therapeutic ratio, lower toxicity, reduced systemic side effects, and stability for several months. The formulation is in particular suitable for treatment of interstitial lung diseases.
Abstract: Disclosed are anti-thrombogenic compositions, methods for their production and products made therefrom. The Anti-thrombogenic compositions comprise a powderized anti-thrombogenic material homogeneously present in a solidifiable matrix material. The anti-thrombogenic material is preferably carbon and more preferably graphite particles. The matrix material is a silicon polymer, a urethane polymer or an acrylic polymer.
Type:
Grant
Filed:
June 30, 1988
Date of Patent:
September 17, 1991
Assignee:
Baylor College of Medicine
Inventors:
George P. Noon, Louis W. Feldman, Julia A. Peterson
Abstract: Osmotically derived liposomal vesicles loaded with an active agent are disclosed. Liposomes, including an entrapped osmotic agent, are contacted one or more times with a washing solution which is hypotonic to the entrapped osmotic agent and which contains active agent. The entrapped osmotic agent in the liposome and the active agent in the washing solution are each present in concentrations causing the liposomes to swell, rupture under osmotic pressure, spill osmotic agent into the washing solution and re-form to encapsulate active agent.
Abstract: The useful life--i.e., emulsion stability and weight loss control--of aqueous air freshener composition can be enhanced via the use therein of small amounts of certain inorganic metal salts.
Type:
Grant
Filed:
August 23, 1989
Date of Patent:
September 10, 1991
Assignee:
Drackett Company
Inventors:
Lyndel D. Dickerson, John A. Ferguson, Donald Cashman
Abstract: A quick drying nail coating composition which contains conventional nail coating ingredients, for example, a film former, a resin, a plasticizer and a solvent and a compound which accelerates the drying time of the composition. The accelerator compound is a hydrocarbon which is chlorinated, fluorinated, fluorinated and chlorinated or mixtures thereof. The composition exhibits accelerated drying times when compared to nail coatings not containing the accelerator compound.
Abstract: A cosmetic composition comprising a long-chain alkyltrimethylol is disclosed. The alkyltrimethylol is represeneted by the formula (I): ##STR1## wherein R is a linear or branched, saturated or unsaturated alkyl group having 8-22 carbon atoms. The composition is applied to various types of cosmetic and exhibits superior extendibility when applied, imparts a non-sticky, fresh feeling upon use, and provides an excellent moisture-retaining effect.
Abstract: Novel diamides having a nitrogen-containing heterocyclic moiety such as pyridyl are disclosed that are useful for improving feed utilization efficiency of ruminants and for improving lactation of lactating ruminants.
Abstract: The invention relates to biodegradable poly((hydroxyalkyl)amino dicarboxylic acid) derivatives of the formula I ##STR1## in which n, m, x, y, z, R and R' have the indicated meanings, and to a process for their preparation and to the use thereof for depot formulations with controlled delivery of active ingredient.
Type:
Grant
Filed:
September 5, 1989
Date of Patent:
August 20, 1991
Assignee:
Hoechst Aktiengesellschaft
Inventors:
Hubert Bader, Diether Ruppel, Axel Walch
Abstract: An agent for setting and caring for the hair, is based on a synergistic combination of (a) 0.1 to 10 percent by weight of a cationic copolymer of vinylimidazolium methochloride and vinylpyrrolidone as a quarternized copolymer of the vinylpyrrolidone and (b) 0.1 to 5.0 percent by weight of tetraoxyethylene laurylether.
Type:
Grant
Filed:
August 23, 1989
Date of Patent:
August 6, 1991
Assignee:
Wella Aktiengesellschaft
Inventors:
Paul Gross, Hildegard Henze, Gunther Lang, Harald Wendel, Liane Stahle
Abstract: Water-miscible pesticidal formulations whose average particle size is at most 200 nm include water, oil, a surfactant, and a cosurfactant, wherein either the oil is a pesticide or the formulation comprises a pesticide dissolved in the oil. The pesticide may be a pyrethroid such as cypermethrin or deltamethrin. The formulations can be molecular solutions, micellar solutions or microemulsions (water-in-oil or oil-in-water) and are generally clear. They exhibit improved activity over conventional pesticidal formulations, particularly in the protection of grain, fruit and brassica plants and against insects, mites and/or larvae. The formulations are especially useful in protecting stored grain, for example against the lesser grain borer weevil (Rhyzopertha dominica).