Patents Examined by Thurman K. Page
  • Pharmaceutical compositions containing epinastine and pseudoephedrine
    Patent number: 7022341
    Abstract: The present invention relates to novel oral pharmaceutical compositions comprising as pharmaceutically active compounds a combination of an antihistaminic-effective amount of epinastine or a pharmaceutically acceptable salt thereof and of a decongestant-effective amount of pseudoephedrine or a pharmaceutically acceptable salt thereof and further comprising suitable pharmaceutically acceptable carriers or excipients. The invention further relates to methods for the preparation these compositions and methods of using them in the treatment of allergic diseases and/or disorders.
    Type: Grant
    Filed: May 29, 2003
    Date of Patent: April 4, 2006
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Sara Abelaira, Daniel Bianchi, Francisco Gel, Victor Denker, Mabel Fernandez, Marta Cicconi de Vidal
  • Pharmaceutical pellets comprising tamsulosin
    Patent number: 7018658
    Abstract: Tamsulosin pellets having an advantageous release profile are formed. The pellets have an enteric coating and release less than 10% of the tamsulosin in two hours in SGF.
    Type: Grant
    Filed: November 14, 2002
    Date of Patent: March 28, 2006
    Assignee: Synthon BV
    Inventor: Johannes J. Platteeuw
  • Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions
    Patent number: 7018655
    Abstract: This invention relates to novel amphiphilic diblock, triblock copolymers and star-shaped block copolymers comprising a biodegradable polymer covalently attached at the polymer ends, to a hydrophilic vinyl polymer, via divalent sulfur atom; to a process for producing the block polymers; to a polymerization process which comprises subjecting the monomers capable of radical polymerization to radical polymerization in the presence of a macromolecular biodegradable chain-transfer agent; and to pharmaceutical compositions comprising the block copolymers loaded with therapeutic agents.
    Type: Grant
    Filed: March 18, 2002
    Date of Patent: March 28, 2006
    Assignee: Labopharm, Inc.
    Inventors: Bhalchandra Shripad Lele, Jean-Christophe Leroux
  • Personal care compositions
    Patent number: 7018625
    Abstract: Personal care compositions, particularly hair care products, include a polymer mixture made from (A) a derivatized polymer of maleic anhydride having defined repeat units of a monomer (e.g. ?-olefin) maleic anhydride alkyl half-ester or full acid, maleamic acid and maleimide, and (B) a compound or polymer having a carboxylic acid functionality. These compositions exhibit excellent high humidity curl retention properties, as well as an advantageous blend of toughness and cohesiveness, and a strong affinity to natural fibers such as keratin-based fibers, e.g. hair, skin, or textiles, such as cotton or wool; and they are also water-soluble and water-resistant.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: March 28, 2006
    Assignee: ISP Investments Inc.
    Inventors: Herbert Ulmer, Timothy Gillece, John Katirgis
  • Patches for external use
    Patent number: 7018647
    Abstract: In order to provide an external skin patch having improved painkilling effect for pains accompanied by inflammation, such as chronic arthrorheumatism, arthrosis deformans or low back pain, an external skin patch is obtained by coating a drug-containing base on a substrate; the drug-containing base comprises an adhesive gel base containing a water soluble polymeric material, a crosslinking agent, water and a humectant as essential components, and a local anesthetic and a nonsteroidal antiphlogistic analgesic agent as medicinal components.
    Type: Grant
    Filed: October 25, 2000
    Date of Patent: March 28, 2006
    Assignee: Teikoku Seiyaku Co., LTD
    Inventors: Keiko Yamasaki, Mitsuji Akazawa, Jutaro Shudo, Keiji Nozaki
  • Method for preparing solid dosage form of desmopressin
    Patent number: 7018653
    Abstract: The present invention relates to a novel method for the preparation of a solid dosage form of desmopressin, or a pharmaceutically acceptable salt thereof, comprising providing a desmopressin containing granulate suitable for compression to a pharmaceutically acceptable tablet, as well as to solid dosage forms, preferably tablets, obtainable by said method.
    Type: Grant
    Filed: December 29, 2003
    Date of Patent: March 28, 2006
    Assignee: Ferring B.V.
    Inventors: Kristen Wannerberger, Hans Lindner, Lars-Erik Olsson, Ann Elisabeth Svensson
  • Composition for filling bone defects
    Patent number: 7019192
    Abstract: The invention is directed toward a formable bone composition for application to a bone defect site to promote new bone growth at the site which comprises a new bone growth inducing compound of demineralized lyophilized allograft bone particles. The particle size ranges from about 0.1 mm to about 1.0 cm and is mixed in a hydrogel carrier containing a sodium phosphate saline buffer, the hydrogel component of the carrier ranging from about 1.0 to 5.0% of the composition and a pH between 6.8–7.4 with one or more additives of a cellular material, growth factor, demineralized bone chips or mineralized bone chips.
    Type: Grant
    Filed: August 19, 2002
    Date of Patent: March 28, 2006
    Assignee: Musculoskeletal Transplant Foundation
    Inventors: Arthur A. Gertzman, Moon Hae Sunwoo
  • Felodipine transdermal device and methods
    Patent number: 7018649
    Abstract: A method of effectively treating hypertension in humans is achieved by administering felodipine via a transdermal formulation. Preferably, the transdermal formulation is applied to the skin of the patient and maintained in contact with the skin for at least about 24 hours days, and preferably for about 3 to about 8 days.
    Type: Grant
    Filed: October 23, 2001
    Date of Patent: March 28, 2006
    Assignee: Euro-Celtique, S.A.
    Inventors: Lino Tavares, Ihor Shevchuk, Mark Alfonso, Geraldine Marcenyac, Kirti Valia
  • Tablet comprising cetirizine and pseudoephedrine
    Patent number: 7014867
    Abstract: The present invention concerns a tablet comprising two distinct segments. More particularly, the invention relates to combinations of two pharmaceutical substances and methods of treatment of allergic disorders.
    Type: Grant
    Filed: June 10, 2002
    Date of Patent: March 21, 2006
    Assignee: UCB Farchim SA
    Inventors: Domenico Fanara, Anthony Guichaux, Monique Berwaer, Michel Deleers
  • Hyaluronic acid gel, process for producing the same, and medical material containing the same
    Patent number: 7014860
    Abstract: Production of a hyaluronic acid gel, which comprises keeping hyaluronic acid in water at a hyaluronic acid concentration of at least 5 wt % in the presence of an acid component in an amount at least equimolar with the carboxyl groups in the hyaluronic acid.
    Type: Grant
    Filed: February 3, 2000
    Date of Patent: March 21, 2006
    Assignee: Denki Kagaku Kogyo Kabushiki Kaisha
    Inventors: Masatoshi Kawata, Akio Okamoto, Yoshiaki Miyata, Kazuhiro Ohshima, Osamu Yamamoto, Teruzou Miyoshi, Kazuhiko Arai, Hironoshin Kitagawa, Toshihiko Umeda, Hiroshi Kaneko
  • Crosslinked copolymers based on non-crosslinked polycarboxylic copolymers
    Patent number: 7014845
    Abstract: The invention relates to cross-linked copolymers based on non cross-linked polycarboxylic copolymers, said non cross-linked copolymers containing at least one polysaccharide. The invention also relates to a process for the preparation of these copolymers and their use in particular as a support in pharmaceutical compositions.
    Type: Grant
    Filed: October 3, 2000
    Date of Patent: March 21, 2006
    Assignee: Societe de Conseils de Recherches et d'Applications Scientifiques (S.C.R.A.S)
    Inventors: Denis Labarre, Nada Lambert, Cathy Ducos, Françis Diancourt
  • Chewable compositions containing a gel-forming extract of psyllium
    Patent number: 7014862
    Abstract: Oral compositions, suitable for chewing, comprising a gel-forming polysaccharide isolated from psyllium seed husks and an excipient that is fast dissolving in the oral cavity, provide good aesthetics and acceptable mouthfeel as perceived by the consumer. The oral compositions are useful for normalizing bowel function, reducing human serum cholesterol levels and treatment of other gastrointestinal disorders.
    Type: Grant
    Filed: February 18, 2003
    Date of Patent: March 21, 2006
    Assignee: The Procter & Gamble Company
    Inventors: Graham John Myatt, Christopher Neil Harrison, Paul Alfred Cimiluca, Theresa Marie Kajs
  • Use methods of treating acne and telangiectasia
    Patent number: 7014858
    Abstract: A method of treating telangiectasia in a human in need thereof comprising administering to said human a tetracycline compound in an amount that is effective to treat telangiectasia, but has substantially no antibiotic activity.
    Type: Grant
    Filed: October 15, 2002
    Date of Patent: March 21, 2006
    Assignee: CollaGenex Pharmaceuticals, Inc.
    Inventor: Robert A. Ashley
  • Phosphate-binding polymers for oral administration
    Patent number: 7014846
    Abstract: Phosphate-binding polymers are provided for removing phosphate from the gastrointestinal tract. The polymers are orally administered, and are useful for the treatment of hyperphosphatemia.
    Type: Grant
    Filed: January 28, 2004
    Date of Patent: March 21, 2006
    Assignee: Genzyme Corporation
    Inventors: Stephen Randall Holmes-Farley, W. Harry Manderville, III, George M. Whitesides
  • High dose solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate and process for making same
    Patent number: 7014866
    Abstract: A solid unit oral pharmaceutical dosage form of amorphous nelfinavir mesylate is provided comprising amorphous nelfinavir mesylate in an amount of from about 400 mg to about 700 mg calculated as nelfinavir base, and a pharmaceutically acceptable water soluble, non-ionic synthetic block copolymer of ethylene oxide and propylene oxide, the copolymer having a melting point of at least about 45° C. and an HLB value at 25° C. of from about 18 to about 29, wherein the copolymer is present from about 40% to about 65% by weight of the nelfinavir mesylate. A hot melt granulation process for making the dosage form is provided.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: March 21, 2006
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Martin Howard Infeld, Wantanee Phuapradit, Navnit Hargovindas Shah, Lin Zhang
  • Rapid dehydration of proteins
    Patent number: 7014869
    Abstract: The present invention relates to protein-coated micro-crystals and their method of preparation. The protein-coated micro-crystals may find particular application in preparing enzymes for use as biocatalysts; preparation of therapeutic proteins for use in pharmaceutical formulations; production of cleansing agents comprising enzymes; production of paints, varnishes, coatings, films and the like comprising proteins which impart protective and/or antifouling properties; production of films, polymers, inks, coatings, electrodes and/or optical materials comprising proteins for diagnostic kits and/or biosensor applications; use of proteins for studies of molecular recognition, molecular binding and inhibitor binding in non-aqueous media; and preparation of protein based food additives.
    Type: Grant
    Filed: November 13, 2001
    Date of Patent: March 21, 2006
    Assignee: University of Strathclyde
    Inventors: Barry Douglas Moore, Marie Claire Parker, Peter James Halling, Johann Partridge, Howard Norman Ernest Stevens
  • Natural formulation for the treatment and prevention of depression, containing St. John's Wort and derivatives of dihydro- and tetrahydrofolic acid
    Patent number: 7014865
    Abstract: The present invention relates to novel compositions containing a combination of the plant St. John's Wort (Hypericum perforatum L.), its extracts of active ingredients and derivatives of dihydro- and tetrahydrofolic acid. This natural formulation is useful for the treatment and prevention of depression with a better effect than the ingredient compounds alone.
    Type: Grant
    Filed: October 8, 1999
    Date of Patent: March 21, 2006
    Assignee: Merck Patent GmbH
    Inventors: Herwig Buchholz, Angela Dudda, Jerzy Meduski
  • Second release phase formulation
    Patent number: 7011849
    Abstract: Formulations are provided herein which allow for a once daily dosing regimen for amoxicillin and clavulanic acid.
    Type: Grant
    Filed: October 10, 2001
    Date of Patent: March 14, 2006
    Assignee: Beecham Pharmaceuticals (Pte) Limited
    Inventors: Kevin H. Storm, Creighton P. Conley, John A. Roush
  • Enteric coated formulation for bisphosphonic acids and salts thereof
    Patent number: 7011847
    Abstract: Pharmaceutical compositions and methods of using the composition are provided. The pharmaceutical composition comprises an inert core surrounded by an active coating containing one or more bisphosphonic acids or salts thereof, a seal coating surrounding the active coating and an enteric coating surrounding the seal coating. Alendronic acid and alendronate sodium trihydrate are the preferred active ingredients. The composition may be provided in the form of pellets in a capsule or Peltabs. The invention further provides methods for the treatment of disorders caused by the abnormal dissolution or deposition of calcium salts using the inventive compositions.
    Type: Grant
    Filed: October 16, 2003
    Date of Patent: March 14, 2006
    Assignee: U & I Pharmaceuticals Ltd.
    Inventors: Amar Lulla, Geena Malhotra
  • Fluoxetine enteric pellets and methods for their preparation and use
    Patent number: RE39030
    Abstract: A superior enteric formulation of the antidepressant drug, fluoxetine, is in the form of enteric pellets of which the enteric layer comprises hydroxypropylmethylcellulose acetate succinate.
    Type: Grant
    Filed: January 28, 2002
    Date of Patent: March 21, 2006
    Assignee: Eli Lilly and Company
    Inventors: Neil Robert Anderson, Roger Garrick Harrison, Daniel Frederick Lynch, Peter Lloyd Oren