Abstract: An intraocular lens system is presented that comprises an electro-active lens comprising multiple independently controllable zones or pixels, and a controller capable of being remotely programmed.

Abstract: Devices and related methods of use are provided for improving heart function. In one embodiment of the present disclosure, a device includes a ring-like structure configured to be secured to a heart valve; at least one elongate member extending from the ring-like structure, wherein an end of the elongate member is configured to be secured to heart geometry other than a heart valve; and an adjustment mechanism for simultaneously altering a dimension of the ring-like structure and a length of the elongate member.

Abstract: An apparatus and method for inserting prosthesis implants into a patient pocket. The apparatus has three openings including a prosthesis opening, a larger proximal opening, and a small distal opening. The apparatus prevents infection; eases insertion and placement; and reduces complications. In use, the inverse bellow is placed through the patient incision while allowing the bellow to be manipulated to force the prosthesis into a surgical pocket of a patient.

Abstract: An intraocular lens for reducing aberrant optical effects includes an anterior surface, a posterior surface and a peripheral region/zone disposed about a central optical axis. The peripheral region/zone has an inflection region/transition area that is inclined with respect to the anterior surface at an angle between about 40 degrees and 120 degrees with respect to the optical axis.

Abstract: A reading enhancement device for preventing and/or treating presbyopia of the eye. The enhancement device is sutured to an outer wall of the sclera for buckling and compressing a portion of the sclera and the ciliary body inwardly and perpendicular to the plane of the sclera and exerting a posterior compression force toward the vitreous humor in the rear of the eye. The enhancement device includes a compression body with a front of the body having semi-circular convex surface. The convex surface is used for engaging, buckling and compressing both a portion of the sclera and the ciliary body of the eye. The compression body also includes an enlarged, rounded first and second end portions and an elongated center portion with the convex surface formed thereon. Also, the compression body includes a rear having an outwardly extending rib portion with a pair of grooves at opposite ends of the rib portion.

Abstract: A capsular ring for insertion into a capsular bag of a patient's eye includes an anterior ring defining a first opening and having a first cross-sectional width and a posterior ring defining a second opening and having a second cross-sectional width. A diameter of the first opening is greater than a diameter of the second opening, and the second cross-sectional width is greater that the first cross-sectional width. The capsular ring further includes a sidewall connecting the first ring and the second ring, the sidewall comprising a plurality of orifices spaced circumferentially around the sidewall.

Abstract: The invention relates to the field of ophthalmic systems and procedures. In particular, the invention relates to the determination of the post-operative position of an intraocular lens (termed “IOL”) in an eye of a patient undergoing lens replacement surgery, which involves determining the position of the existing crystalline lens in the pre-operative eye of the patient and using that information and a single numerical constant to predict the post-operative intraocular lens position. Related methods, and computer programs for performing the methods of the invention, are also disclosed.

Abstract: The present invention relates to an intraocular lens, in particular a ciliary intraocular lens having at least one optic and one haptic element.

Abstract: A capsular ring includes substantially circular anterior and posterior surfaces each defining a central void of the capsular ring, at least a portion of the anterior and posterior surfaces being substantially flat. The capsular ring further includes an exterior surface extending around the circumference of the capsular ring between the anterior surface and the posterior surface, wherein there is a sharp transition between the exterior surface and both the anterior surface and the posterior surface. The capsular ring further includes a plurality of orifices spaced circumferentially around the exterior surface and a plurality of haptics spaced circumferentially around the exterior surface and extending outwardly from the capsular ring; each of the plurality of haptics being configured, upon insertion of the capsular ring into a capsular bag of a patient's eye, to engage an equatorial region of the capsular bag of the patient's eye.

Abstract: A vascular device having a plurality of struts having a distal portion and a proximal portion. The distal portion of the struts are retained in a converged position. The struts diverge radially outwardly. A plurality of vessel penetrating members extend from the proximal portion of the struts for engaging the internal wall of the vessel, wherein release of the retention of the distal portions of the struts causes the distal portions to move outwardly away from the longitudinal axis and the proximal portions of the struts to move inwardly toward the longitudinal axis such that the vessel engaging members pull the internal wall of the vessel radially inwardly.

Abstract: An apparatus and method for inserting prosthesis implants into a patient pocket. The apparatus includes a universal bellows, prosthesis, and a retractor. The apparatus prevents infection; eases insertion and placement; and reduces complications. In use, the retractor anchors the universal bellows to the patient while allowing the bellows to be manipulated to force the prosthesis into a surgical pocket of a patient.

Abstract: This apparatus treats the lens capsule so as to increase accommodation of the eye. The treatment of the lens capsule may comprise treating a portion of the lens capsule so as to stiffen the treated portion and improve accommodation of the eye. The intermediate portion of the lens capsule may be located between an optically used central portion of the lens capsule and a peripheral portion of the lens capsule connected to zonules of the eye. The stiffened intermediate portion of the lens capsule can improve coupling of the peripheral portion of the lens capsule to the central portion of the lens capsule, such that an amount of accommodation of the optically used central portion of the lens is increased. As the force of the lens capsule to a lens disposed within the lens capsule is increased, the lens may comprise the natural lens of the eye or an artificial lens such as an accommodative IOL.

Abstract: The present disclosure is directed to a branched endoprosthesis comprising a graft component and at least one support component. In various embodiments, the branched endoprosthesis comprises a body portion and at least two leg portions, wherein at least two legs are in an aligned configuration for ease of cannulation. In various embodiments, at least one leg is in an open configuration for ease of cannulation. Cannulation methods are also taught.

Abstract: A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation.

Abstract: A medical implant including an anchor portion including a plurality of arms adapted to engage an internal tissue wall of a body from two opposite faces, wherein the anchor portion is configured such that at least one of the arms does not have an entirely overlapping arm on the other side of the wall and an opening portion adapted to define an opening for blood flow through the internal tissue wall, when the anchor portion engages the wall.

Abstract: A prosthetic heart valve is provided with a cuff having features which promote sealing with the native tissues even where the native tissues are irregular. The cuff may include a portion adapted to bear on the LVOT when the valve is implanted in a native aortic valve. The valve may include elements for biasing the cuff outwardly with respect to the stent body when the stent body is in an expanded condition. The cuff may have portions of different thickness distributed around the circumference of the valve in a pattern matching the shape of the opening defined by the native tissue. All or part of the cuff may be movable relative to the stent during implantation.

Abstract: Provided herein are methods for treating an individual having (suffering from) an acute myocardial infarction and drug eluting stents useful for treating such individuals. These methods include treating an individual by introducing, such as by surgically inserting, at a site of an acute coronary artery occlusion upstream of the site of acute myocardial infarction, a drug eluting stent (DES) that is capable of eluting from 25 pg to 950 pg of IGF-1 directly into the coronary circulation. The treatment is specifically directed to stimulation of repair or survival of damaged cardiac muscle or left ventricular remodeling.

Abstract: An intraocular lens with a lens comprises a main lens part having a main lens surface and a main optical axis defining radial, tangential and axial directions; and a recessed part having a recess surface and extending between said main optical axis and a circumference of said lens, the recessed part comprising a secondary lens part with a secondary lens surface having a positive relative optical power with respect to an optical power of said main lens surface. The main lens surface extends in an outward radial direction towards a main lens outer circumference section remote from said the optical axis.

Abstract: Systems and methods involving an intraocular implant with input and/or output electronics are described. In some embodiments, the system includes an intraocular lens having at least one optic operably coupled to a haptic, one or more input electronics on the haptic and/or the optic; and one or more output electronics on the haptic and/or the optic for receiving and/or transmitting data.

Abstract: A plate haptic for an accommodating intraocular lens. The plate haptic has a haptic body that is substantially rigid in a longitudinal direction and substantially flexible in a transverse direction. A chassis is integral to the haptic body. The chassis causes the haptic body to be substantially more rigid in a longitudinal direction than in a transverse direction.