Patents Examined by Weihua Fan
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Patent number: 11965182Abstract: Transgenic plants having enhanced yield and having enhanced seed yield are disclosed. The transgenic plants are transformed with a transgenic polynucleotide encoding one or more metabolic enzymes. The metabolic enzymes can be from any biological source. The transgenic polynucleotide(s) comprises a nucleic acid sequences encoding the metabolic enzymes under the control of functional plant promoters, the one or more metabolic enzymes are targeted to the plastids by the addition of plastid targeting signals. Optionally the functional plant promoters are seed specific promoters and the metabolic enzymes are targeted to the plastids by the addition of plastid targeting peptide heterologous to the metabolic enzymes. Methods of making the transgenic plants and transgenic polynucleotides are disclosed. The magnitude of the increases in seed yield achieved with these transgenic plants are unprecedented.Type: GrantFiled: October 11, 2021Date of Patent: April 23, 2024Assignee: YIELD10 BIOSCIENCE, INC.Inventors: Meghna Malik, Jihong Tang, Kristi D. Snell
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Patent number: 11963498Abstract: A sorghum seed comprising in its genome at least one polynucleotide encoding a polypeptide having an alanine to tyrosine substitution at position 93 of the sorghum AHAS protein large subunit. The plant has increased resistance to one or more herbicides, for example from the imidazolinone group, as compared to wild-type sorghum plants. The sorghum plant may comprise in its genome, one, two, three or more copies of a polynucleotide encoding a mutated large subunit of sorghum AHAS or a sorghum AHAS polypeptide of the invention. In this context, the sorghum plant may be tolerant to any herbicide capable of inhibiting AHAS enzyme activity. For example, the sorghum plant may be tolerant to herbicides of the imidazolinones type, such as imazethapyr, imazapir, and imazapic or to herbicides of the sulfonylurea group.Type: GrantFiled: September 26, 2019Date of Patent: April 23, 2024Assignee: Advanta Holdings BVInventors: Vicente Trucillo Uriarte, Andrés Daniel Zambelli, Marcos Kaspar, Pedro Alejandro Pardo
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Patent number: 11965171Abstract: The present invention refers to a plant or plant part comprising a polynucleotide encoding a wildtype or mutated cellulose synthase (CESA) polypeptide, the expression of said polynucleotide confers to the plant or plant part tolerance to CESA-inhibiting herbicides, such as azines.Type: GrantFiled: June 16, 2022Date of Patent: April 23, 2024Assignee: BASF SEInventors: Stefan Tresch, Doreen Schachtschabel, Mihiret Tekeste Sisay, Jens Lerchl, Julia Major, Florian Vogt, Frederick Calo, Jill Marie Paulik
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Patent number: 11957103Abstract: An object of the present invention is to provide an F1 hybrid or a portion thereof, and use of the F1 hybrid or a portion thereof. The F1 hybrid of the present invention is an F1 hybrid between Nicotiana umbratica and Nicotiana kawakamii.Type: GrantFiled: November 29, 2022Date of Patent: April 16, 2024Assignee: JAPAN TOBACCO INC.Inventor: Shun Yamauchi
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Patent number: 11950563Abstract: The present disclosure provides tobacco Nic1b locus and associated genes (e.g., a group of ERF genes). Also provided are tobacco plants with altered total alkaloid and nicotine levels and commercially acceptable leaf grade, their development via breeding or transgenic approaches, and production of tobacco products from these tobacco plants. Further provided are compositions and methods for producing tobacco plants having novel mutations or alleles to reduce nicotine levels. Further provided are sequence polymorphisms and molecular markers for breeding tobacco with reduced nicotine or alkaloids while maintaining tobacco leaf grade and tobacco product quality.Type: GrantFiled: January 11, 2019Date of Patent: April 9, 2024Assignee: ALTRIA CLIENT SERVICES LLCInventors: Sreepriya Pramod, Marcos Fernando de Godoy Lusso, Jesse Frederick, Andrew Carl Adams, Dongmei Xu
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Patent number: 11952580Abstract: A recombinant host cell is disclosed for producing psilocybin and related compounds, such as metabolic intermediates of the psilocybin biosynthesis. Also provided is a method of producing psilocybin and its synthesis intermediates and related compounds, such as metabolic intermediates of the psilocybin biosynthesis, in the host cell, as well as a production system for producing them.Type: GrantFiled: March 11, 2019Date of Patent: April 9, 2024Assignee: TEKNOLOGIAN TUTKIMUSKESKUS VTT OYInventors: Dominik Mojzita, Heiko Rischer, Anssi Rantasalo, Kirsi-Marja Oksman-Caldentey, Joosu Kuivanen
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Patent number: 11946061Abstract: The invention relates to novel methods and compositions for conferring tolerance to glyphosate to plants. The invention also provides glyphosate-tolerant plants, seeds, tissue, cells, and plant parts comprising modified EPSP synthases and recombinant DNA molecules encoding modified EPSP synthases, as well as methods of producing the same and the use thereof.Type: GrantFiled: August 19, 2022Date of Patent: April 2, 2024Assignee: Monsanto Technology LLCInventors: Guillermo A. Asmar-Rovira, Stephen M. Duff, Shirley X. Guo, Jingdong Liu, R. Douglas Sammons, Lei Shi
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Patent number: 11932861Abstract: A recombinant vector according to an embodiment is for genome editing without inserting a replicon into the plant genome in a T0 generation plant. The recombinant vector includes a geminivirus-based replicon between the sequence of LB (left border) and sequence of RB (right border) of Ti plasmid. A method of genome editing without inserting a replicon into the plant genome in a T0 generation plant according to an embodiment includes transforming a plant cell by inserting a foreign gene to the aforementioned recombinant vector.Type: GrantFiled: September 10, 2019Date of Patent: March 19, 2024Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION GYEONGSANG NATIONAL UNIVERSITYInventors: Jae Yean Kim, Tien Van Vu, Jihae Kim, Se Jeong Jeong, Hyun Jeong Kim, Seo-Jin Park, Mil Thi Tran, Velu Sivankalyani, Yeon Woo Sung, Thi Hai Duong Doan, Dibyajyoti Pramanik, Mahadev Rahul Shelake, Geon Hui Son
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Patent number: 11932865Abstract: The present invention provides for compositions and methods for producing crop plants that are resistant to herbicides. In particular, the present invention provides for wheat plants, plant tissues and plant seeds that contain altered acetyl-CoA carboxylase (ACCase) genes and proteins that are resistant to inhibition by herbicides that normally inhibit the activity of the ACCase protein.Type: GrantFiled: September 2, 2021Date of Patent: March 19, 2024Assignee: COLORADO WHEAT RESEARCH FOUNDATION, INC.Inventors: Michael Hal Ostlie, Scott Haley, Philip Westra, Victoria Ashley Anderson
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Patent number: 11920129Abstract: The present invention relates to ligation and/or assembly of nucleic acid molecules. Particularly, a double-stranded target nucleic acid having overhangs of at least one nucleotide is ligated with another nucleic acid molecule capable of forming a stem-loop structure with an overhang of at least one nucleotide. The invention is suitable for tagging nucleic acid molecules. In specific embodiments, the overhangs can be produced by chemical cleavage of phosphorothioate-modified nucleic acid molecules. The invention further relates to the amplification of the ligated product, and using the resultant amplicon for assembly of multiple nucleic acid fragments.Type: GrantFiled: October 24, 2018Date of Patent: March 5, 2024Assignee: National University of SingaporeInventors: Kang Zhou, Xiaoqiang Ma, Hong Liang
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Patent number: 11917975Abstract: A soybean cultivar designated 05410624 is disclosed. The invention relates to the seeds of soybean cultivar 05410624, to the plants of soybean cultivar 05410624, to the plant parts of soybean cultivar 05410624, and to methods for producing progeny of soybean cultivar 05410624. The invention also relates to methods for producing a soybean plant containing in its genetic material one or more transgenes and to the transgenic soybean plants and plant parts produced by those methods. The invention also relates to soybean cultivars or breeding cultivars, and plant parts derived from soybean cultivar 05410624. The invention also relates to methods for producing other soybean cultivars, lines, or plant parts derived from soybean cultivar 05410624, and to the soybean plants, varieties, and their parts derived from use of those methods. The invention further relates to hybrid soybean seeds, plants, and plant parts produced by crossing cultivar 05410624 with another soybean cultivar.Type: GrantFiled: October 7, 2021Date of Patent: March 5, 2024Assignee: M.S. Technologies, L.L.C.Inventor: Justin T. Mason
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Patent number: 11913035Abstract: Provided are compositions comprising polynucleotides encoding modified diacylglycerol acyltransferase-1 (DGAT1) polypeptides having improved properties, such as increased enzymatic activity and/or increased stability. Plants, plant cells, seed, grain and comprising the polynucleotides are provided which have one or more of increased fatty acid or protein content. Methods of generating the polynucleotides in plant cells include transformation and genetic modification. Methods of employing the polynucleotides in plants, methods for increasing DGAT1 activity in a plant, and methods for increasing fatty acid content or protein content in a plant are provided.Type: GrantFiled: September 19, 2022Date of Patent: February 27, 2024Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: Kayla S Flyckt, Kristin Haug Collet, Zhan-Bin Liu, Keith R Roesler, Bo Shen, Laura L Wayne
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Patent number: 11913005Abstract: This invention relates to CRISPR-Cas nucleases codon optimized for expression in plants and nucleic acid constructs encoding base editors comprising a CRISPR-Cas nuclease and a deaminase domain, wherein the nucleic acid constructs are optimized for expression in a plant. The invention further relates to methods of modifying nucleic acids using the nucleic acid constructs.Type: GrantFiled: October 20, 2022Date of Patent: February 27, 2024Assignee: Pairwise Plants Services, Inc.Inventor: Nathaniel Graham
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Patent number: 11905519Abstract: Engineered Cry1Da amino acid sequences are provided that exhibit improved Lepidopteran insecticidal activity and an enhanced Lepidopteran spectrum compared to the naturally occurring Cry1Da protein toxin. Polynucleotide sequences intended for use in expression of the improved proteins in plants are also provided. Particular embodiments provide compositions containing insect inhibitory amounts of the engineered proteins, as well as recombinant plants, plant parts, and seeds containing polynucleotide constructs encoding one or more of the improved engineered proteins.Type: GrantFiled: July 26, 2022Date of Patent: February 20, 2024Assignee: Monsanto Technology LLCInventors: James A. Baum, Thomas Cerruti, Stanislaw Flasinski, Xiaoran Fu, Arlene R. Howe, Sara Ann Salvador
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Patent number: 11895980Abstract: The invention relates to the novel cotton variety designated 19R243B3XF. Provided by the invention are the seeds, plants, plant parts and derivatives of the cotton variety 19R243B3XF. Also provided by the invention are methods of using cotton variety 19R243B3XF and products derived therefrom. Still further provided by the invention are methods for producing cotton plants by crossing the cotton variety 19R243B3XF with itself or another cotton variety and plants and seeds produced by such methods.Type: GrantFiled: January 26, 2022Date of Patent: February 13, 2024Assignee: Monsanto Technology LLCInventors: Dawn E Fraser, Darren G Jones, Vivek Sharma
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Patent number: 11898153Abstract: Compositions having pesticidal activity and methods for their use are provided. Compositions include isolated and recombinant polypeptides having pesticidal activity, recombinant and synthetic nucleic acid molecules encoding the polypeptides, DNA constructs and vectors comprising the nucleic acid molecules, host cells comprising the vectors, and antibodies to the polypeptides. Polynucleotide sequences encoding the polypeptides can be used in DNA constructs or expression cassettes for transformation and expression in organisms of interest. The compositions and methods provided are useful for producing organisms with enhanced pest resistance or tolerance. Transgenic plants and seeds comprising a nucleotide sequence that encodes a pesticidal protein of the invention are also provided. Such plants are resistant to insects and other pests. Methods are provided for producing the various polypeptides disclosed herein, and for using those polypeptides for controlling or killing a pest.Type: GrantFiled: August 10, 2021Date of Patent: February 13, 2024Assignee: AgBiome, Inc.Inventors: Jessica Parks, Kira Bulazel Roberts, Rebecca E. Thayer
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Patent number: 11891613Abstract: Biological strains, compositions, and methods of using the strains and compositions for reducing overall insect damage.Type: GrantFiled: December 1, 2021Date of Patent: February 6, 2024Inventors: Brian J Gibbons, Steven D Gruver, Lu Liu, Young-Jun Park, Jun-Zhi Wei, Genhai Zhu
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Patent number: 11879128Abstract: The present invention relates to methods for producing wheat lines that are low gliadin, low-gluten and transgene-free using genome editing. Also described are nucleic acid constructs and sgRNA molecules for use in genome editing, as well as genetically altered plants obtained by these methods.Type: GrantFiled: June 5, 2018Date of Patent: January 23, 2024Assignee: CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC)—DELEGACIÓN ANDALUCÍAInventors: Francisco Barro Losada, Javier Gil Humanes, Susana Sánchez León
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Patent number: 11877556Abstract: Compositions and methods for reducing the level of nornicotine and N?-nitrosonornicotine (NNN) in tobacco plants and plant parts thereof are provided. The compositions comprise isolated polynucleotides and polypeptides for a root-specific nicotine demethylases, CYP82E10, and variants thereof, that are involved in the metabolic conversion of nicotine to nornicotine in these plants. Compositions of the invention also include tobacco plants, or plant parts thereof, comprising a mutation in a gene encoding a CYP82E10 nicotine demethylase, wherein the mutation results in reduced expression or function of the CYP82E10 nicotine demethylase. Seed of these tobacco plants, or progeny thereof, and tobacco products prepared from the tobacco plants of the invention, or from plant parts or progeny thereof, are also provided. Methods for reducing the level of nornicotine, or reducing the rate of conversion of nicotine to nornicotine, in a tobacco plant, or plant part thereof are also provided.Type: GrantFiled: March 7, 2022Date of Patent: January 23, 2024Assignee: North Carolina State UniversityInventors: Ralph E. Dewey, Ramsey S. Lewis
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Patent number: 11873500Abstract: Provided herein are genetic markers and a coding sequence associated with a low- or ultra-low anatabine trait in tobacco.Type: GrantFiled: February 28, 2022Date of Patent: January 16, 2024Assignee: ALTRIA CLIENT SERVICES LLCInventors: Chengalrayan Kudithipudi, Alec J. Hayes, Robert Frank Hart, Yanxin Shen, Jesse Frederick, Dongmei Xu