Patents Examined by Yanzhi Zhang
  • Patent number: 10702463
    Abstract: Oral compositions and methods of use thereof are provided herein. The oral compositions comprise a first component comprising at least one Eh-raising compound and a pharmaceutically acceptable carrier, and a second component comprising at least one zinc compound, an anti-microbial agent and a pharmaceutically acceptable carrier.
    Type: Grant
    Filed: September 6, 2018
    Date of Patent: July 7, 2020
    Assignee: The Research Foundation for the State University of New York
    Inventors: Marvin Cohen, Susanne Cohen, Robert G. Flynn
  • Patent number: 10688127
    Abstract: Methods for use of structures based on graphene-related materials are disclosed. These structures can be utilized for manipulating the cell transmembrane potential in various biomedical applications.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: June 23, 2020
    Inventor: Elena Molokanova
  • Patent number: 10676785
    Abstract: This disclosure relates to novel detergents for use in various procedures including, for example, nucleic acid amplification reactions such as polymerase chain reaction (PCR). Methods for preparing the modified detergents are also described.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: June 9, 2020
    Assignee: Life Technologies Corporation
    Inventors: Parul Angrish, Zhiwei Yang, Jonathan Wang
  • Patent number: 10675246
    Abstract: Orally administrable compositions comprising calcium, methods of administration, and methods of making the same.
    Type: Grant
    Filed: March 15, 2014
    Date of Patent: June 9, 2020
    Assignee: CEROLIFE LLC
    Inventors: Manish S. Shah, Ray J. DiFalco
  • Patent number: 10675258
    Abstract: Provided herein are pharmaceutical compositions and formulations comprising mixed salts of gamma-hydroxybutyrate (GHB). Also provided herein are methods of making the pharmaceutical compositions and formulations, and methods of their use for the treatment of sleep disorders such as apnea, sleep time disturbances, narcolepsy, cataplexy, sleep paralysis, hypnagogic hallucination, sleep arousal, insomnia, and nocturnal myoclonus.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: June 9, 2020
    Assignee: Jazz Pharmaceuticals Ireland Limited
    Inventors: Clark P. Allphin, Michael DesJardin
  • Patent number: 10668016
    Abstract: The present disclosure relates to pharmaceutically acceptable complex formulae comprising complexes of Abiraterone acetate and pharmaceutically acceptable excipients, process for the preparation thereof and pharmaceutical compositions containing them. The complex formulae of the present disclosure have improved physicochemical properties which results in reduced food effect which allows significant dose reduction and the abandoning of the requirement of taking the drug on an empty stomach.
    Type: Grant
    Filed: October 17, 2018
    Date of Patent: June 2, 2020
    Assignee: NanGenex Nanotechnology Incorporated
    Inventors: Réka Angi, Tamás Jordán, Orsolya Basa-Dénes, Tamás Solymosi, Zsolt Ötvös, Hristos Glavinas, Genovéva Filipcsei
  • Patent number: 10668041
    Abstract: The invention provides compositions and methods for treatment of epilepsy in an animal. In one embodiment, a method for treating epilepsy in a companion animal can comprise administering to the companion animal a food composition comprising a medium chain triglyceride (MCT), wherein the MCT is present in the food composition in an effective amount for reducing or preventing seizures when the food composition is administered to the companion animal.
    Type: Grant
    Filed: August 30, 2017
    Date of Patent: June 2, 2020
    Assignee: Societe des Produits Nestle SA
    Inventors: Yuanlong Pan, Brian Michael Zanghi, Jean-Christophe Bouthegourd
  • Patent number: 10653133
    Abstract: A solid material adapted to kill bacteria in planktonic, spore and biofilm states is lethal toward a wide spectrum of gram positive and gram negative bacteria as well as other microbes. The solid material includes a significant amount of one or more surfactants entrained in a crosslinked polymeric network.
    Type: Grant
    Filed: May 10, 2012
    Date of Patent: May 19, 2020
    Assignee: Next Science IP Holdings Pty Ltd
    Inventor: Matthew F. Myntti
  • Patent number: 10646446
    Abstract: The present invention relates to a pharmaceutical composition comprising a) a therapeutically effective amount of a compound of formula (I), or a pharmaceutically acceptable salt thereof, b) one or more, e.g. 1, 2 or 3, surfactants with lubricant properties; c) one or more, e.g. 1, 2 or 3, dry binders with disintegrant properties; d) one or more, e.g. 1, 2 or 3, fillers, and e) one or more, e.g. 1, 2 or 3, disintegrants.
    Type: Grant
    Filed: May 1, 2018
    Date of Patent: May 12, 2020
    Assignee: Novartis AG
    Inventors: Hong Wen, Natrajan Kumaraperumal, Richard Nause
  • Patent number: 10647736
    Abstract: A method of enhancing the growth of an animal is provided. The method includes causing the animal to ingest or absorb an effective amount of a preparation obtainable by a process including, bringing a tyrosinate moiety into contact with an Fe(III)-containing substance, optionally wherein the tyrosinate moiety is tyrosine and it is brought into contact with the Fe(III)-containing substance in the presence of a base, or wherein the tyrosinate moiety is a tyrosine salt and it is brought into contact with an Fe(III)-containing substance. Methods for inhibiting, reducing, or preventing biofilm formation or buildup on a surface; the treatment of, inhibition of growth of, and inhibition of colonization by, bacteria, both in biological and non-biological environments; disinfecting surfaces, potentiating the effects of antibiotics and other anti-microbial agents, and increasing the sensitivity of bacteria and other microorganisms, to anti-microbial agents are also provided.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: May 12, 2020
    Assignee: Akeso Biomedical, Inc.
    Inventors: Dlawer Ala'Aldeen, Jafar Mahdavi, Panos Soultanas
  • Patent number: 10639250
    Abstract: Disinfection foam having low levels of alcohol, comprising at least water, foaming agent, and polymeric type silver ion source, and a method of manufacturing the same. The present antimicrobial foams are especially suitable for hand sanitizer foams, shaving foams, dry cleansing foams for full body, leave on shampoos, face cleansing foams and multipurpose dry cleaning.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: May 5, 2020
    Assignee: Nolla Antimicrobial Ltd
    Inventors: Juha-Pekka Pöyry, Jyri Nieminen
  • Patent number: 10632060
    Abstract: The present disclosure relates generally to a composition comprising at least one capped oligomer, at least one solvent, at least one film former, and at least one monomer or polymer, said composition having a sward hardness <10 and >1 when applied to a glass plate.
    Type: Grant
    Filed: June 25, 2018
    Date of Patent: April 28, 2020
    Assignee: Revlon Consumer Products Corporation
    Inventors: David Valia, Robert Sandewicz
  • Patent number: 10617618
    Abstract: The present disclosure relates to agents for the oxidative coloring of keratinic fibers, which are characterized in hat they contain derivatives of anisole as novel developer molecules.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: April 14, 2020
    Assignee: Henkel AG & Co. KGaA
    Inventors: Antje Gebert-Schwarzwaelder, Ralph Nemitz, Astrid Kroos, Annika Koenen
  • Patent number: 10610556
    Abstract: Compositions for appetite control and/or regulation or loss of weight are described. The described compositions comprise a unique combination of ingredients, the combination including at least botanical substances, amino acids, and one or more metals, and may comprise and in some embodiments do further comprise one or more vitamins and/or caffeine. The compositions are taken by mouth and provide a multi-targeted approach for the regulation and control of appetite for subjects taking the composition. The composition is preferably taken before a meal. A recommended dose includes at least one dose of the described composition per day.
    Type: Grant
    Filed: September 17, 2015
    Date of Patent: April 7, 2020
    Assignee: Therapeutic Solutions LLC
    Inventor: Sue Ann Alter
  • Patent number: 10609923
    Abstract: A solid material adapted to kill bacteria in planktonic, spore and biofilm states is lethal toward a wide spectrum of gram positive and gram negative bacteria as well as other microbes. The solid material includes a significant amount of one or more surfactants entrained in a crosslinked polymeric network.
    Type: Grant
    Filed: August 11, 2018
    Date of Patent: April 7, 2020
    Assignee: Next Science IP Holdings Pty Ltd
    Inventor: Matthew Franco Myntti
  • Patent number: 10603401
    Abstract: The present invention relates to skin dressings that are useful in the treatment of conditions associated with tissue ischaemia and skin lesions including those that are infected, such as burns and surgical wounds and chronic wounds such as but not limited5 to diabetic foot ulcers and venous leg ulcers. The skin dressings are also useful to effect transdermal delivery of pharmaceutically active agents.
    Type: Grant
    Filed: November 28, 2016
    Date of Patent: March 31, 2020
    Assignees: Edixomed Limited, First Water Limited
    Inventors: Hugh Munro, Nicholas Boote
  • Patent number: 10603285
    Abstract: An object of the present invention is to provide [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate as a stabilized pharmaceutical solid preparation, and also to provide a method for preparing the stabilized pharmaceutical solid preparation. The object can be attained by a pharmaceutical solid preparation comprising [(1R,5S,6S)-6-(aminomethyl)-3-ethylbicyclo[3.2.0]hept-3-en-6-yl]acetic acid monobenzenesulfonate which is compound represented by the following formula (I) in combination with (i) one or two or more components selected from the group consisting of D-mannitol, lactose, corn starch, and crystalline cellulose, (ii) carmellose calcium, and (iii) colorants.
    Type: Grant
    Filed: March 17, 2016
    Date of Patent: March 31, 2020
    Assignee: DAIICHI SANKYO COMPANY, LIMITED
    Inventors: Shinichiro Tajiri, Shinji Yoshinaga, Yurika Ozaki
  • Patent number: 10582915
    Abstract: The present disclosure relates to a film for oral hemostasis and wound protection and, more particularly, to a film for oral hemostasis and wound protection which, being attached to a wound area in an oral cavity, delays or prevents microbleeds and controls medicinal component release. The film provided by the present disclosure is capable of including a polyol, an alcohol and a biodegradable polymer in the state of partial swelling, thereby locally absorbing blood or pus or arresting hemorrhage. Moreover, due to its high elongation ratio, the film provided by the present disclosure is capable of maintaining its adhesive force even when having blood, saliva and pus absorbed inside an oral cavity and conveniently deforming according to the shape of a seriously corrugated local area, which causes only slight foreign body sensation even after a long period of time of attachment on to the local area.
    Type: Grant
    Filed: October 28, 2016
    Date of Patent: March 10, 2020
    Assignee: TBM Company
    Inventor: Seiyeong Yun
  • Patent number: 10584306
    Abstract: The present invention relates to microemulsions and methods of preparing and using the microemulsions.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: March 10, 2020
    Assignees: Board of Regents of the University of Oklahoma, Novus International, Inc.
    Inventors: Scott Long, Graciela Arhancet, Brian Grady, Jeff Harwell, Guangzhe Yu
  • Patent number: 10584243
    Abstract: Provided herein are polymers and methods for their use in binding a phosphate containing biological macromolecules. Specifically, the methods and uses provided herein may be used to inhibit thrombin binding to polyphosphate or as an antithrombotic agent for the treatment of stroke, acute coronary syndrome, pulmonary embolism, atrial fibrillation, venous and arterial thromboembolism, disseminated intravascular coagulation (DIC), deepvein thrombosis (DVT), peripheral artery disease, trauma-induced coagulopathy, extracorporeal circulation, cancer-associated thrombosis, sepsis, septic shock, Systemic Inflammatory Response Syndrome (SIRS), or inflammation.
    Type: Grant
    Filed: December 19, 2018
    Date of Patent: March 10, 2020
    Assignees: The University of British Columbia, The Board of Trustees of the University of Illinois
    Inventors: Jayachandran Kizhakkedathu, James H. Morrissey, Richard J. Travers, Rajesh Shenoi, Manu Thomas Kalathottukaren