Abstract: Silicalite particles, methods of making silicalite particles, systems comprising silicalite particles and methods for using silicalite particles to separate ethanol from water.
Type:
Grant
Filed:
August 5, 2015
Date of Patent:
May 3, 2016
Assignee:
Algenol Biotech LLC
Inventors:
Ryan Lively, Michelle Dose, Ronald Chance, Benjamin McCool
Abstract: At least one of transesterification, esterification and hydrolysis can occur with a method as shown and described herein. Preferably pressures are lower than supercritical pressures for the alcohol employed and the conversion rate is at least 95%, if not 99% in a single reactor which may be counter or co-flow or even a batch process. Meanwhile, bound glycerin may be separated from alkyl esters for at least some processes.
Type:
Grant
Filed:
September 26, 2014
Date of Patent:
May 3, 2016
Inventors:
Travis Danner, Philip N. Brown, Mark Mauss
Abstract: The present invention is related to the process for the preparation ospemifene or (Z)-2-[4-(4-chloro-1,2-diphenyl-but-1-enyl)phenoxy]ethanol (I) and to intermediate compounds used in the process.
Type:
Grant
Filed:
October 17, 2013
Date of Patent:
April 26, 2016
Assignee:
FERMION OY
Inventors:
Jan Tois, Ainoliisa Pihko, Arne Grumann
Abstract: Pleckstrin homology domain binding compounds, pharmaceutical compositions including such compounds, and methods for their use are described herein.
Type:
Grant
Filed:
January 5, 2015
Date of Patent:
April 26, 2016
Assignees:
Board of Regents, The University of Texas System, Arizona Board of Regents on behalf of the University of Arizona
Inventors:
Daruka Mahadevan, Emmanuelle J. Meuillet, Eugene A. Mash, Jr., Vijay M. Gokhale, Garth Powis, Shuxing Zhang
Abstract: Compounds of formula (I) are disclosed. Compounds according to the invention bind to and are agonists, antagonists or inverse agonists of the CB2 receptor, and are useful for treating inflammation. Those compounds which are agonists are additionally useful for treating pain.
Type:
Grant
Filed:
January 11, 2011
Date of Patent:
April 19, 2016
Assignee:
Boehringer Ingelheim International GmbH
Inventors:
Alessandra Bartolozzi, Angela Berry, Doris Riether, Monika Ermann, James Edward Jenkins, Innocent Mushi
Abstract: A method that manufacturers an optically active carboxylic acid ester at high yield and high enantioselectivity is provided. An optically active carboxylic acid ester is manufactured at high yield and high enantioselectivity by reacting a racemic carboxylic acid and a specific alcohol or phenol derivatives in a polar solvent having a dipole moment of 3.0 or higher in the presence of an acid anhydride and an asymmetric catalyst, esterifying one enantiomer of the racemic carboxylic acid at high selectivity, and increasing the amount of esterified carboxylic acid by racemizing the optically active carboxylic acid which is the other enantiomer not used in esterification.
Type:
Grant
Filed:
June 7, 2012
Date of Patent:
April 19, 2016
Assignee:
TOKYO UNIVERSITY OF SCIENCE EDUCATIONAL FOUNDATION ADMINISTRATIVE ORGANIZATION
Inventors:
Isamu Shiina, Kenya Nakata, Keisuke Ono
Abstract: A process of integrated system formed by coupling of fixed bed, jetting floating bed, and separating unit, aimed to provide a new process and equipment of higher efficiency, which integrates multi-type reactors and separation is provided. Reaction materials undergo preliminary reaction in fixed bed reactor and intensified reaction in jetting floating bed reactor, and then separation in the subsequent separation system. Unreacted materials will be returned to the raw material intermediate storage tank for mixing with fresh materials, as raw materials for continued reaction. During this process, materials first pass the fixed bed reactor once to achieve certain conversion rate, and then enter the jetting floating bed reactor for intensified reaction. When the product reaches required concentration, the materials will enter subsequent separation equipment for separation.
Abstract: A method for separation of liquid mixtures with a polybenzoxazole (PBO) membrane from a self-cross-linked aromatic polyimide polymer membrane is provided.
Type:
Grant
Filed:
July 29, 2015
Date of Patent:
April 12, 2016
Assignee:
UOP LLC
Inventors:
Chunqing Liu, Zara Osman, Angela N. Troxell
Abstract: The invention provides a simple, efficient, environmentally friendly catalytic system for direct carboxylation reactions using CO2 under mild conditions. A single step heterogeneous catalytic process for preparation of alkynyl carboxylic acids is disclosed.
Type:
Grant
Filed:
January 25, 2013
Date of Patent:
April 5, 2016
Assignee:
Council of Scientific & Industrial Research
Abstract: This invention relates to liquid crystal compounds of formula I containing cyclopentyl group and difluoromethyleneoxy linking group. Liquid crystal compounds of formula I have a large dielectric anisotropy, high clearing points, and a fast response speed, thereby having great significance to formulate a liquid crystal mixture.
Abstract: The invention relates to the production of 2-octyl acrylate of high purity and in good yield, that includes the recycling of economically upgradable products, such as un-reacted reactants and catalyst. The process uses ethyl titanate in solution in 2-octanol or 2-octyl titanate as a tranesterification catalyst and employs a purification train comprising only two distillation columns.
Type:
Grant
Filed:
January 14, 2013
Date of Patent:
March 29, 2016
Assignee:
Arkema France
Inventors:
Alain Riondel, Coralie Graire, Marc Esch
Abstract: A device and a process for producing high purity CO by electrolysis of CO2 in a Solid Oxide Electrolysis Cell stack and a gas separation unit, also the gas separation unit may be a Solid Oxide Electrolysis Cell stack.
Type:
Grant
Filed:
February 26, 2013
Date of Patent:
March 15, 2016
Assignee:
Haldor Topsoe A/S
Inventors:
Friis Claus Pedersen, Bøgild John Hansen, Thomas Rostrup-Nielsen, Jens Ulrik Nielsen, Henrik Olsson, Kim Hedegaard Andersen
Abstract: Disclosed herein are novel motuporamine compounds that act as anti-metastatic agents with low toxicity and high anti-migration activity. The non-toxic, anti-metastatic agents may be given to patients with potential or actual metastatic cancers, such as pancreatic cancers, alone in combination with known and/or new therapies to help block the growth and spread of tumor(s).
Type:
Grant
Filed:
March 13, 2013
Date of Patent:
February 23, 2016
Assignee:
University of Central Florida Research Foundation, Inc.
Abstract: The present application provides novel pyridine compounds and pharmaceutically acceptable salts or prodrugs thereof. Also provided are methods for preparing these compounds. These compounds are useful in inhibiting CYP17 activity by administering a therapeutically effective amount of one or more of the compounds to a patient. By doing so, these compounds are effective in treating conditions associated with CYP17 activity. A variety of conditions can be treated using these compounds and include diseases which are characterized by abnormal cellular proliferation. In one embodiment, the disease is cancer, such as prostate cancer.
Type:
Grant
Filed:
August 18, 2014
Date of Patent:
February 23, 2016
Assignee:
Asana Biosciences, LLC
Inventors:
Roger Astbury Smith, Nicholas James Laping, Aranapakam M. Venkatesan, Raghava Reddy Kethiri, Chandregowda Venkateshappa, Bheemashankar Kulkarni, Purushottam Dewang, Rajendra Kristam, Rajesh Devraj
Abstract: The invention relates to a process for preparing metal difluorochelatoborates, in which a metal bis(chelato)borate of the formula M[BL2] is reacted with boron trifluoride and a metal fluoride (MF) and/or a metal salt of the chelating ligand (M2L) where M+ is a monovalent cation selected from the group consisting of lithium, sodium, potassium and ammonium NR4+, where R?H, alkyl (C1 to C8) and L is a chelating agent having two terminal oxygen atoms and having the general formula (II), where: when m=1 and Y1 and Y2 together with C1 form a carbonyl group, n=0 or 1 and o=0 or 1 and R1 and R2 are each, independently of one another, H or alkyl having from one to eight carbon atoms (C1-C8) and Y3, Y4 are each, independently of one another, OR3 (R3?C1-C8-alkyl), then n or o?1: p=0 or 1 and when n and o=0, p=1; or Y1, Y2, Y3, Y4 are each, independently of one another, OR3 (R3?C1-C8-alkyl), m=1, n=0 or 1, o=1 and p=0; or C2 and C3 are members of a 5- or 6-membered aromatic or heteroaromatic ring (with N, O or S as heter
Type:
Grant
Filed:
November 14, 2012
Date of Patent:
February 16, 2016
Assignee:
Rockwood Lithium GmbH
Inventors:
Ulrich Wietelmann, Peter Rittmeyer, Ute Emmel
Abstract: The present invention relates to a method of producing a carbamate compound, comprising reacting a fluorine-containing carbonic diester compound represented by formula (1) and a non-aromatic diamine compound represented by formula (2) without using a catalyst, to thereby produce a carbamate compound represented by formula (3), and a method of producing an isocyanate compound represented by formula (20) from the carbamate compound without using a catalyst, wherein R represents a fluorine-containing monovalent aliphatic hydrocarbon group, and A represents a divalent aliphatic hydrocarbon group, a divalent alicyclic hydrocarbon group or a divalent aromatic-aliphatic hydrocarbon group.
Abstract: The present invention relates to novel acid-free quaternized nitrogen compounds, to the preparation thereof and to the use thereof as a fuel and lubricant additive, more particularly as a detergent additive, as a wax antisettling additive (WASA) or as an additive for reducing internal diesel injector deposits (IDID); to additive packages which comprise these compounds; and to fuels and lubricants thus additized. The present invention further relates to the use of these acid-free quaternized nitrogen compounds as a fuel additive for reducing or preventing deposits in the injection systems of direct-injection diesel engines, especially in common-rail injection systems, for reducing the fuel consumption of direct-injection diesel engines, especially of diesel engines with common-rail injection systems, and for minimizing power loss in direct-injection diesel engines, especially in diesel engines with common-rail injection systems.
Type:
Grant
Filed:
July 22, 2014
Date of Patent:
February 9, 2016
Assignee:
BASF SE
Inventors:
Wolfgang Grabarse, Harald Boehnke, Christian Tock, Cornelia Roeger-Goepfert, Ludwig Voelkel
Abstract: Provided is a method for industrially producing a conjugated Z-alken-yn-yl acetate such as Z-13-hexadecen-11-yn-yl acetate which is a sex pheromone component of a pine processionary moth, and an intermediate for the conjugated Z-alken-yn-yl acetate under mild conditions at a high yield. More specifically, provided is a method for producing a conjugated Z-alken-yn-yl acetate (5) comprising the steps of: reacting an ?-halo-2-alkynal (1) with an alkylidene triphenylphosphorane (3) through a Wittig reaction to obtain a conjugated Z-alken-yn-yl halide (4), and acetoxylating the conjugated Z-alken-yn-yl halide (4) into a conjugated Z-alken-yn-yl acetate (5).
Abstract: A crosslinkable compound comprising trifluorovinyl has a structure of Formula (I). A method for preparing the crosslinkable compound and a light emitting device prepared from the compound are also disclosed.
Abstract: The present invention relates to a process for producing porous or finely divided solid inorganic materials, the surface of which has been modified with at least one organic substance, under supercritical conditions, wherein the supercritical conditions are lowered by addition of an inert organic substance.
Type:
Grant
Filed:
February 4, 2014
Date of Patent:
February 2, 2016
Assignee:
BASF SE
Inventors:
Johann Martin Szeifert, Michael Kutschera