Abstract: A prosthetic heart valve configured to replace a native heart valve and having a support frame configured to be reshaped into an expanded form in order to receive and/or support an expandable prosthetic heart valve therein is disclosed, together with methods of using same. The prosthetic heart valve may be configured to have a generally rigid and/or expansion-resistant configuration when initially implanted to replace a native valve (or other prosthetic heart valve), but to assume a generally expanded form when subjected to an outward force such as that provided by a dilation balloon or other mechanical expander.

Abstract: A UE may, responsive to detecting a power-related condition, send a message to induce the master node to release the secondary node. Such a message can include a message reporting a radio link failure of the secondary node, or, if a channel quality indicator is configured for at least some of the secondary cells of the secondary node, reporting a low CQI value so that the network can cease scheduling on such cells. Alternatively, in a carrier aggregation (CA) mode, with the UE connected to a single node comprising a primary cell and one or more secondary cells, the UE may not control which and how many secondary cells with which it communicates. In such a scenario, if such secondary cells are configured for channel quality indicator reporting, the UE may report a low CQI value so that the node will cease scheduling data on such cells.

Abstract: A time-multiplexing resonant drive scheme is described that reuses an inductor circuit for multiple functional purposes in a Mixed Reality (MR) device. A driver circuit and a multiplexer circuit are dynamically configured by a controller circuit for three operating modes. In the first mode, energy is coupled from a battery to the inductor circuit in a forward direction to charge the inductor circuit and generate a positive power supply voltage. In the second mode, energy is coupled from to the inductor circuit in a reverse direction to charge the inductor circuit and generate a negative power supply voltage. In the third mode, the inductor is operated with an antenna as part of a resonance drive circuit, where facial movements of the user can be detected based on the response. Reduced component count and reduced cost requirements are achieved by the described scheme.

Abstract: Methods, apparatus, systems and articles of manufacture to determine headphone adjustment for portable people meter listening to encoded audio streams are disclosed. An example system disclosed herein includes meter data analyzer circuitry to determine an audience estimate for streaming media based on media data measured by a media meter, the media meter to measure the streaming media based on an identification of the streaming media in ambient audio collected by a microphone of the media meter, and data analyzer circuitry to calculate at least one headphone adjustment factor based on a first determined proportion of an audience that listens to streaming media via headphones and a second determined proportion of the audience that listens to streaming media without headphones.

Abstract: Implementations described herein relate to methods, systems, and computer-readable media to localize dynamic content. In some implementations, a computer-implemented method includes receiving visual content associated with a game from a first client locale, the visual content including text being represented at the first client locale by a first language, converting the text to generate translated text in at least a second language associated with a second client locale, and storing the translated text in a database in association with the visual content.

Abstract: Described herein is a computer implemented method for adding an element to a design. The method includes displaying a design canvas and, in response to detecting an insert element user interaction, displaying a quick-add GUI. Text query data is received via the quick-add GUI and a submit query user interaction is detected. In response to determining that the submit query user interaction is associated with an add defined element command, a first design element that is associated with the add defined element command is added to the design.

Abstract: A computer-implemented method of quantifying a strength of association of genes associated with a phenotype and a contribution of rare variants to a phenotype response by calculating a weighted burden score for a plurality of associated genes with a specified phenotype, wherein the burden score identifies identifying consequential, non-random association in a cohort between carrier status of each of the associated genes and a phenotype response to presence in the associated genes of one or more rare pathogenic variants. Respective effective strength scores are determined for the consequential, non-random association for genes selected from the associated genes based on respective burden scores at per-gene resolution.

Abstract: A woven retention device that is configured to receive a fastener in a bone hole can be configured to promote bone ingrowth and impede biofilm formation. The woven retention device can be made of woven filaments that outline apertures of varying sizes and shapes and can serve as an interface between the fastener and the bone material. In a first relaxed state, the interwoven filaments can outline apertures of varying sizes and shapes within a predetermined range and in a second constricted state inside the bone hole with the fastener the interwoven filaments can outline apertures of decreased area that still fall within the predetermined range. The woven retention device can be configured to allow for optimal bone growth while at the same time minimizing the likelihood that biofilm forms thereon.

Abstract: Systems and methods of additively manufacturing leak resistant objects are disclosed. Provided herein are methods of forming objects having walls and/or surfaces that are resistant to leaks. Objects disclosed are formed from or manufactured from compositions, including metals, polymers, and combinations thereof. Objects provided herein are made from methods of forming individual shells, forming of series shells, and layer-by-layer forming of objects. Further disclosed are methods of interconnecting shells, layers, and processes for transitioning therebetween the shells and layers.

Abstract: Various embodiments of the invention provide systems and methods to assist or guide an arthroscopic surgery (e.g., surgery of the shoulder, knee or hip) or other surgical procedure by the placement of arbitrary landmarks in one or more locations in surgical field of view. The systems and methods comprise steps of receiving a video stream from an arthroscopic or other imaging device; receiving one or more sets of coordinates of one or more landmarks; overlaying the one or more landmarks on the video stream; and displaying the overlay on one or more display devices intraoperatively so as to be used by an operator during the arthroscopic or other medical procedure.

Abstract: A computer-implemented method of performing an optimized burden test for a particular gene, in which an optimal combination of a maximum allele count and a minimum pathogenicity score threshold that maximize significance of burden testing for rare deleterious variants are determined using a grid search protocol. Each combination of maximum allele count and minimum pathogenicity score threshold is tested with a t-test to obtain effect size and p-value. The combination of allele count and pathogenicity score threshold with the most significant p-value is selected as the optimal parameters for the rare deleterious variant burden test for a particular gene.

Abstract: In one aspect, a method is disclosed wherein an artificial intelligence (AI) enabled automated flow synthesis platform is configured to generate optimized synthesizing recipes which enable a sequence to be synthesized using an automated flow process. The method includes receiving a synthesizing recipe including parameters used during the automated flow process to synthesize the sequence, receiving spectral data from detectors monitoring the automated flow process in a reaction chamber, where the spectral data corresponds to a reaction point in the automated flow process, and determining, based on indicators associated with the spectral data, characteristics of a chemical reaction at the reaction point in the automated flow process. An artificial intelligence engine determines the chemical reaction. The method includes associating, based on the spectral data, the synthesizing recipe with the chemical reaction.

Abstract: One or more systems, devices and/or methods of use provided herein relate to a device that can support a signal generation. A current-mode end-to-end signal path can include a digital to analog converter (DAC) operating in current-mode and an upconverting mixer, operating in current-mode and operatively coupled to the DAC. Analog inputs and outputs of the DAC and upconverting mixer can be represented as currents, and the DAC can generate a baseband signal. The DAC and upconverting mixer each can comprise switching transistors of the same type, such as p-type metal-oxide semiconductor (PMOS) switching transistors. In one or more embodiments, a current source and a diode-connected transistor can be arranged in parallel in the current-mode signal path, and the current source passes a static current, while the diode-connected transistor passes both a static current and a dynamic current.

Abstract: A monitoring device configured to be attached within a portion of an ear of a subject includes an elastomeric arm having opposite first and second end portions. A sensing element is located at the elastomeric arm second end portion and includes at least one energy emitter configured to direct energy at a target region of the ear and at least one detector configured to detect an energy response signal from the target region or a region adjacent the target region. The monitoring device is configured such that the elastomeric arm first end portion engages the ear at a first location within the ear and such that the elastomeric arm resiliently bends such that a surface of the sensing element is urged into contact with the ear at a second location within the ear.

Abstract: Various aspects and embodiments are directed to a streamlined computer device and a graphical user interface that organizes interface elements into views of computer content for presentation to a user. Various views of digital media content permits users to easily and efficiently access various digital media content. Different views are used to provide an interface that is responsive to configurations of the device and responsive to activity being performed by the user. Aspects include permitting the user to maintain and manage digital media content libraries. According to some embodiments, the libraries comprise user digital media content and references digital media content. Functionality provided to a user can be tailored to the type of content displayed, accessed and/or managed. According to various aspects, methods and systems are provided for accessing and managing digital media libraries on a streamlined computing device with a plurality selectable I/O profiles.

Abstract: Provided is a gas sensor and methods of monitoring the same. The gas sensor may detect gas restrictions within the gas sensor. The gas sensor may include a test gas diffusion path allowing for monitoring of restrictions within the gas sensor. A pulse of test gas may be electrochemically generated into a void disposed between the membrane and capillary of the gas sensor. The resulting transient signal on the sensing electrode may be analyzed to determine the degree of restriction present in the gas sensor.

Abstract: Systems and methods for enhanced SSO, which can avoid faults in known protocols and standards for access delegation. For example, the enhanced SSO can use a shared security mechanism, such as a keychain or keystore, for sharing vendor identity over mobile applications without some of the pitfalls of using cookies. And, a connector code can bind the mobile applications to each other so that only the enhanced SSO is required for a user to log in to the mobile applications and remain logged in to the applications on one or more mobile devices.

Abstract: A system that incorporates teachings of the present disclosure may include, for example, receiving at a computer device a plurality of stimulus signals generated by one or more gaming accessory devices of a gamer controlling a gaming application, generating a plurality of gaming stimulations based on the plurality of stimulus signals, generating a plurality of gaming action results from the gaming application responsive to the plurality of gaming stimulations, combining the plurality of gaming action results and the plurality of gaming stimulations to generate a plurality of hardware statistics associated with the gamer, and transmitting to a social network the plurality of hardware statistics associated with the gamer.

Abstract: Systems and methods for material processing using wafer scale waves of precisely controlled electrons in a DC plasma is presented. A surface floating potential of a substrate placed atop a stage in a positive column of the DC plasma is adjusted and maintained to a reference potential. A periodic biasing signal referenced to the reference potential is capacitively coupled to the stage to control a surface potential at the substrate according to: an active phase for provision of kinetic energy to free electrons in the DC plasma for activation of targeted bonds at the surface of the substrate; a neutralization phase for repelling of the free electrons from the surface of the substrate; and an initialization phase for restoring an initial condition of the surface floating potential.

Abstract: A method and apparatus for lifting and setting a golf ball on a golf tee without bending include a shaft holding a lifter-setter tool to lift and set a golf ball onto a golf tee plus a parking tray with means for parking a lifter-setter tool upright on the parking tray. The lifter-setter tool is parked upright on the parking tray with Readily Dissociable Fasteners (RDFs) including an upright parking pin fastened to the parking tray and hook-and-loop fasteners, touch fasteners, and mushroom head fasteners, inter alia.