Abstract: A cosmetic composition is provided comprising: (a) metal oxide particles; and (b) cross-linked, non-emulsifying organopolysiloxane elastomer, wherein organo-functionalised silicone fibrils are bonded to and extend away from the surface of the metal oxide particles.

Abstract: Architectures and techniques for treating conditions of the eye, such as presbyopia, utilize sources of treatment energy, such as electromagnetic energy emitting devices, to implement non-corneal manipulations. According to these devices and methods, the sources of treatment energy are activated to direct energy onto parts of the eye, such as the conjunctiva and sclera, to treat presbyopia. The treatments can affect at least one property of the eye and enhance an accommodation of the eye.

Abstract: A magnetic electron exciter includes a rotor adapted to be rotated within a preselected range of rotational speeds, and having a plurality of magnets mounted therein preselected distances from the rotational axis of the rotor. A plurality of coils are positioned adjacent to the rotor, whereby rotation of the rotor creates an electrical current in the coils. First and second electrodes are spaced apart a predetermined distance, and are electrically connected with the coils to create an arc between the electrodes when the rotor is rotated relative to the coils.

Abstract: Compounds, compositions and methods are provided that are useful in the treatment or prevention of a condition or disorder mediated by PPAR? or PPAR?. In particular, the compounds of the invention modulate the function of PPAR? or PPAR?. The subject methods are particularly useful in the treatment and/or prevention of diabetes, obesity, hypercholesterolemia, rheumatoid arthritis and atherosclerosis.

Abstract: The present invention is directed to benzazole compounds that inhibit ?-site amyloid precursor protein-cleaving enzyme (BACE) and that may be useful in the treatment or prevention of diseases in which BACE is involved, such as Alzheimer's disease. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which BACE is involved.

Abstract: The present invention provides a novel cellulase nucleic acid sequence, designated BagCel, and the corresponding BagCel amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding BagCel, recombinant BagCel proteins and methods for producing the same.

Abstract: An automated food processing system is provided that allows food to be dispensed, fried and packaged in a container, for example, an individual portion-sized container. The system includes separate automated modules for dispensing, frying and packaging food. An automated dispensing device dispenses a predetermined portion of food from a bulk storage container or food dispensing magazine. Food is dispensed from the automated dispensing device to an automated fry device that can include at least one circular fry wheel having a plurality of food containing compartments. After the food is fried, it is dispensed from the fry device to an automated packaging device. The automated packaging device dispenses food to a container, for example, an individual portion-sized container that is retrieved, erected and held in position for filling by an automated container handling system. After a food container is filled, a conveyor system transports the container to a pick-up location.

Abstract: A device for tensioning a flexible drive member includes a pair of opposing contact elements adapted to simultaneously engage upper and lower spans of the flexible drive member. The device further includes a connecting member to draw the contact elements together and position the contact elements at a selected distance from each other to provide a predetermined tension to the flexible drive member. The tensioning device may be implemented in a print substrate transport subsystem adapted to move media through a print system.

Abstract: A method and system for preloading data is provided. Resources are preloaded on a client before they are needed by an application. Application hints and static resources lists may be used to indicate resources are needed. The application may begin execution before receiving all of the resources associated with the application. Preloading may be done during execution of an application, or when the application is not executing. Preloading allows an application to run smoothly without consuming more resources than are needed by an application. A prediction graph may be generated that is used in predicting the resources that are likely to be needed by the application. An analyzer may also be used to simulate the system and adjust parameters used in creating the prediction graph.

Abstract: An intramedullary implant for mounting within an intramedullary canal of a bone is disclosed. The intramedullary implant includes a lower stem portion, an upper stem portion, and a modular sleeve body. The modular sleeve body is connected to one of the lower stem portion or the upper stem portion. The sleeve body includes an inner portion that covers at least a segment of the upper stem portion and has one or more longitudinally extending bone engagement members for engagement with the bone.

Abstract: In a process for converting methane to aromatic hydrocarbons, a feed containing methane is contacted with a dehydrocyclization catalyst in a reaction zone under conditions effective to convert the methane to aromatic hydrocarbons. The reaction zone is contained within a reactor and the reactor or an internal component of the reactor has at least one surface that is chemically exposed to the feed and is formed from a refractory material that exhibits a carbon uptake (mass of carbon absorbed per unit of exposed metal surface area) of less than 25 g/m2 when exposed to mixture of 50 vol % methane and 50 vol % H2 at 900° C. for 168 hours.

Abstract: Apparatus and method for quickly disconnecting a wetted parts subassembly from a paint spray gun wherein the wetted parts subassembly includes a spray tip, pump cylinder and piston and paint cup components including a pump housing cylinder support carrying the pump cylinder and having a pair of protrusions formed on a pump housing cylinder support, a frame having a pair of slots aligned to receive the protrusions when the pump housing cylinder support is received in the frame, a locking lever pivotably attached to the frame adjacent at least one of the slots and movable between a latched position wherein the pump housing cylinder support is retained to the frame, and an unlatched position wherein the pump housing cylinder support is removable from the frame. A passive retention feature frictionally engages the wetted parts subassembly with the frame when the wetted parts subassembly is received in the frame.

Abstract: Systems and methods for manipulating light with high index contrast waveguides clad with crystalline substances having that exhibit large nonlinear electro-optic constants ?2 and ?3. Waveguides fabricated on SOI wafers and clad with crystalline materials such as barium titanate are described. Embodiments of waveguides having slots, electrical contacts, and input waveguide couplers are discussed. Waveguides having closed loop structures (such as rings and ovals) as well as linear or serpentine waveguides, are described. Optical signal processing methods, such as optical rectification and optical modulation, are disclosed.

Abstract: A durable optical film or element includes a polymerized structure having a microstructured surface and a plurality of surface modified colloidal nanoparticles of silica, zirconia, or mixtures thereof. Display devices including the durable microstructured film are also described.

Abstract: A method and system for triggering a local emergency system using wireless means. Existing local emergency systems are exploited through an ordinary mobile user device implementing the present invention. Disadvantages of current local emergency system are overcome by facilitating a user to remotely report emergency service request with more accurate location information automatically conveyed by the present invention. A mobile user device is configured to activate an emergency service station of a local emergency system without knowing the location of the emergency service station and without physically accessing and operating the emergency service station.

Abstract: Methods, systems, and computer program products for providing recommendations for an activity to a user are provided. In one method, the method tracks status information of a plurality of users, and detects a trigger for providing recommendations for an activity. In response the trigger, the method identifies a cluster of users based on the status information of the users. The method further retrieves profiles and behavioral characteristics of the users in the identified cluster, and provides one or more recommendations for the activity to the user based, at least in part, upon the behavioral characteristics and the profiles.

Abstract: The invention provides extraction columns for the purification of an analyte (e.g., a biological macromolecule, such as a peptide, protein or nucleic acid) from a sample solution, as well as methods for making and using such columns. The columns typically include a bed of extraction media positioned in the column, often between two frits. In some embodiments, the extraction columns employ modified pipette tips as column bodies. In some embodiments, the extraction columns are comprised of frits having a low pore. In some embodiments, the frits of the extraction columns have a pore volume of less than one microliter or less than 10% of the interstitial volume of the bed of extraction media.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. The present invention further provides a method of treatment or prophylaxis of a viral infection in a subject comprising administering to said subject an effective amount of a compound of formula (I) or a pharmaceutically acceptable derivative, salt or prodrug thereof. Pharmaceutical compositions comprising a compound of formula (I) are also provided.