Patents by Inventor A. K. Ghosh

A. K. Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds for treatment of Alzheimer's disease
    Patent number: 8703947
    Abstract: Described herein are compounds, and pharmaceutical compositions, methods, and uses thereof for treating Alzheimer's disease.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: April 22, 2014
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • CLIP MOUNTED HOLDER FOR ARTICLE
    Publication number: 20140077056
    Abstract: An article holder is disclosed. The article holder includes a mounting clip with a top and bottom member pivotally attached to one another and spring loaded so as to clip mount to a base element. In certain embodiments, the mounting clip includes a groove in a top surface adapted to receive an article such as an electronic tablet device. Thus, the article holder can clip to a base element such as an airplane tray table and hold the article in a viewing position. A second groove oriented in a direction substantially perpendicular to the first groove may be provided for an alternate mode of use. In further embodiments, the groove may be formed by a groove wall in the top member and a lip on a cradle element which projects into the clip.
    Type: Application
    Filed: September 19, 2012
    Publication date: March 20, 2014
    Inventor: Krishnan K. Ghosh
  • Inhibitors of Memapsin 2 Cleavage for the Treatment of Alzheimer's Disease
    Publication number: 20140066488
    Abstract: Proteases such as memapsin 2 are important enzymes, playing roles in a variety of diseases including Alzheimer's Disease. The inventors have developed inhibitors of memapsin 2 and methods of use therefore in the treatment of disease.
    Type: Application
    Filed: August 28, 2013
    Publication date: March 6, 2014
    Applicants: Purdue Research Foundation, Oklahoma Medical Research Foundation
    Inventors: Jordan Tang, Venkateswararao Kalapala, Arun K. Ghosh
  • ATTACK RESISTANT CONTINUOUS NETWORK SERVICE TRUSTWORTHINESS CONTROLLER
    Publication number: 20140053269
    Abstract: An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher.
    Type: Application
    Filed: October 24, 2013
    Publication date: February 20, 2014
    Applicant: George Mason Research Foundation, Inc.
    Inventors: Anup K. Ghosh, Yih Huang, Arun Sood
  • PROCESSES AND INTERMEDIATES FOR PREPARING SUBSTITUTED HEXAHYDROFURO [2,3-b] FURANS
    Publication number: 20130338380
    Abstract: The invention described herein pertains to processes and compounds useful in the preparation of bis-tetrahydrofurans. The invention described herein also pertains to compounds useful for treating HIV infections.
    Type: Application
    Filed: November 30, 2011
    Publication date: December 19, 2013
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Arun K. Ghosh, Cuthbert D. Martyr
  • Methods and devices for exchanging peer parameters between network devices
    Patent number: 8605624
    Abstract: Methods and devices are provided for detecting whether peer ports interconnecting two network devices can perform a novel protocol called Exchange Peer Parameters (“EPP”). If the peer ports are so configured to perform EPP, EPP services are exchanged between the peer ports. In a first phase, information is exchanged about peer port configurations of interest. In a second phase, the results of the exchange of information are applied to hardware and/or software of the respective ports, as needed.
    Type: Grant
    Filed: August 29, 2008
    Date of Patent: December 10, 2013
    Assignee: Cisco Technology, Inc.
    Inventors: Tushar Desai, Shashank Gupta, Praveen Jain, Kalyan K. Ghosh
  • Method of treating HIV infection
    Patent number: 8597876
    Abstract: Disclosed is a method of treating human immunodeficiency virus (HIV) infection in an antiretroviral treatment-experienced mammal, which involves administering to the mammal an effective amount of a compound of the formula: or a pharmaceutically acceptable salt, a prodrug, or an ester thereof, or a pharmaceutically acceptable composition of the compound, the salt, the prodrug, or the ester thereof, wherein A, X, Q, W, m, and R2-R6 are as defined herein.
    Type: Grant
    Filed: October 11, 2007
    Date of Patent: December 3, 2013
    Assignees: The United States of America, as represented by the Secretary, Department of Health and Human Services, Board of Trustees of the University of Illinois
    Inventors: John W. Erickson, Sergei V. Gulnik, Hiroaki Mitsuya, Arun K. Ghosh
  • Synthesis of macrocyclic cancer chemotherapy agents and methods of use
    Patent number: 8580975
    Abstract: Herein are described a process for forming a quaternary carbon useful in the preparation of macrolactones, an enantioselective synthesis of (+)-peloruside A, and methods for treating a patient in need of relief from cancer or a cancer-related disease. The described processes are useful for preparing compounds containing quaternary carbons, including structural analogs and derivatives of peloruside A.
    Type: Grant
    Filed: January 9, 2009
    Date of Patent: November 12, 2013
    Assignee: Purdue Research Foundation
    Inventors: Arun K Ghosh, Xiaoming Xu
  • CATALYST FOR LIGHT NAPHTHA AROMATIZATION
    Publication number: 20130296625
    Abstract: Methods for preparing bound non-acidic germanium zeolite catalysts arc disclosed, where the preparation is reproducible and scalable and where the catalysts have similar or the same activity and selectivities of a standard naphtha aromatization catalyst and methods for aromatizing naphtha.
    Type: Application
    Filed: May 2, 2012
    Publication date: November 7, 2013
    Inventors: Ashim K. Ghosh, Scott A. Stevenson, Neeta Kulkarni, Mike Mier, Balamurali K. Nair, Dustin Farmer
  • COMPOUNDS AND METHODS FOR TREATING HIV
    Publication number: 20130289067
    Abstract: Inhibitors of HIV-1 protease and compositions containing them are described. Use of the inhibitors and compositions containing them to treat HIV, AIDS, and AIDS-related diseases is described.
    Type: Application
    Filed: June 27, 2013
    Publication date: October 31, 2013
    Inventors: Arun K. GHOSH, Bruno D. Chapsal, Hiroaki Mitsuya
  • Attack resistant continuous network service trustworthiness controller
    Patent number: 8572735
    Abstract: An attack resistant continuous network service trustworthiness controller comprising: state estimation module(s), response selection module(s), actuation module(s), and client dispatcher communication module(s) for maintaining the availability and integrity of online server(s). The state estimation module(s) are configured to generate state estimate(s) for online server(s) using behavior data obtained using sensor module(s). The response selection module(s) are configured to determine corrective action(s) to maintain the availability and integrity of online server(s) when state estimate(s) indicate that the integrity of an online server(s) is compromised. The actuation module(s) are configured to activate actuator(s) based upon the corrective action(s). Client dispatcher communication module(s) are configured to communicate online server availability information to a client dispatcher.
    Type: Grant
    Filed: March 31, 2008
    Date of Patent: October 29, 2013
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Anup K. Ghosh, Yih Huang, Arun Sood
  • Fused tricyclic ether carbamates and their use
    Patent number: 8563597
    Abstract: Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Methods of using the disclosed compounds for treating patients infected with HIV are also described.
    Type: Grant
    Filed: September 2, 2011
    Date of Patent: October 22, 2013
    Assignees: Purdue Research Foundation, National University Corporation Kumamoto University
    Inventors: Arun K. Ghosh, Chun-Xiao Xu, Hiroaki Mitsuya, Garth Parham
  • HIV protease inhibitors and methods for using
    Patent number: 8501961
    Abstract: Compounds that inhibit proteolytic enzymes of Human Immunodeficiency Virus (HIV) are described. Preparation of the inhibitors, pharmaceutical compositions containing them, and uses of the compounds or compositions for the treatment of HIV infections are also described.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: August 6, 2013
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • FUSED TRICYCLIC ETHER CARBAMATES AND THEIR USE
    Publication number: 20130158094
    Abstract: Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are describes. Methods of using the disclosed compounds for treating patients infected with HIV are also described.
    Type: Application
    Filed: September 2, 2011
    Publication date: June 20, 2013
    Applicant: PURDUE RESEARCH FOUNDATION
    Inventors: Arun K. Ghosh, Chun-Xiao Xu, Hiroaki Mitsuya, Garth Parham
  • Automatic correction of application based on runtime behavior
    Patent number: 8448139
    Abstract: A system and associated method for automatically correcting an application based on runtime behavior of the application. An incident indicates a performance of the application in which a problem object produces an outcome that had not been expected by a user or by a ticketing tool. An incident flow for the problem object is automatically analyzed. Actual run of the application renders a forward data flow and at least one backward data flow is simulated from an expected outcome of the problem object. The forward data flow and the backward data flow(s) are compared to create a candidate fault list for the problem object. A technical specification to correct the candidate fault list and a solution to replace the application are subsequently devised.
    Type: Grant
    Filed: October 5, 2009
    Date of Patent: May 21, 2013
    Assignee: International Business Machines Corporation
    Inventor: Anup K. Ghosh
  • PYRROLIDINE COMPOUNDS WHICH INHIBIT BETA-SECRETASE ACTIVITY AND METHODS OF USE THEREOF
    Publication number: 20130102593
    Abstract: Described herein are novel beta-secretase inhibitors and methods for their use, including methods of treating Alzheimer's disease.
    Type: Application
    Filed: October 9, 2009
    Publication date: April 25, 2013
    Inventors: Geoffrey M. Bilcer, Thippeswamy Devasamudram, Sudha V. Ankala, John C. Lilly, Chunfeng Liu, Hui Lei, Arun K. Ghosh, Makoto Inoue
  • COMPUTER-IMPLEMENTED INFORMATION REUSE
    Publication number: 20130103682
    Abstract: Embodiments of the present invention relate to an approach for reusing information/knowledge. Specifically, embodiments of the present invention provide an approach for retrieving previously stored data to satisfy queries (e.g., jobs/tickets) for solutions to problems while maintaining privacy/security of the data as well as ensuring the quality of the results. In a typical embodiment, a query for a solution to a problem is received and details are extracted therefrom. Using the details, a search is performed on a set of data stored in at least one computer storage device. Based on the search, a set of results will be generated and classified into a set of categories. In any event, the quality of each of the set of results will be assessed based on the usefulness of the set of results.
    Type: Application
    Filed: October 20, 2011
    Publication date: April 25, 2013
    Applicant: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Anup K. Ghosh, Sugata Ghosal, Nandakishore Kambhatla, Rose C. Kanjirathinkal, Asidhara Lahiri, Debapriyo Majumdar, Shajith I. Mohamed, Karthik Visweswariah
  • HEPATITIS C THERAPIES
    Publication number: 20130078218
    Abstract: The invention provides methods for treating hepatitis C viral infections and related viral infections, as well as compounds and compositions that are useful for treating such infections.
    Type: Application
    Filed: March 26, 2012
    Publication date: March 28, 2013
    Inventors: Yarlagadda S. Babu, Pooran Chand, Minwan Wu, Pravin L. Kotian, V. Satish Kumar, Tsu-Hsing Lin, Yahya El-Kattan, Ajit K. Ghosh
  • Quinazoline inhibitors of BACE 1 and methods of using
    Patent number: 8394807
    Abstract: There is provided a dihydroquinazoline compound of the formula or a pharmaceutically acceptable salt thereof, wherein the values of the radicals are defined herein, as well as a pharmaceutical composition containing the compound, and a method of using the compound for the treatment of Alzheimer's disease.
    Type: Grant
    Filed: November 20, 2009
    Date of Patent: March 12, 2013
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • Prefetch mechanism for bus master memory access
    Patent number: 8356143
    Abstract: A system and method for optimizing memory bus bandwidth, is achieved by utilization of the memory bus, either by utilizing the idle time of the memory bus, or by prioritizing prefetch requests to exploit the bank structure of the external memory. When a bus master of the memory bus makes a request to access a particular line in a memory device, the memory controller generates a request for accessing a line next to the current line that is requested by the bus master. Data corresponding to the next line is retrieved from the memory device and stored in the memory-controller when the memory bus is idle. The stored data may be served to a bus master upon request for the data. However, the memory bus is not engaged when the data stored in the memory controller is served. Therefore idle time of the memory bus is utilized.
    Type: Grant
    Filed: October 22, 2004
    Date of Patent: January 15, 2013
    Assignee: NVIDIA Corporatin
    Inventors: Ravi P. Bulusu, Subir K. Ghosh