Patents by Inventor A. K. Ghosh

A. K. Ghosh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20170002320
    Abstract: A novel cytosolic 58 kd phosphoprotein induced during bone marrow stem cell (BM) differentiation into dendritic cells (DC) during in vitro cultivation with the cytokine GM-CSF by addition of antisera to an 82 kd BM cell surface protein generating cultivatable dendritic progenitor cells (DP). Genes, methods for preparing them as well as early DP have been provided. Potential uses/advantages lie in the study of BM differentiation and innate immunity due to stimulatory/inhibitory DC, contribution of BM and DP to inflammation during infection and carcinogenesis, tumor promotion/regression, identification of BM-derived blood cells, T-cell activation/regulation/tolerance and inflammation.
    Type: Application
    Filed: November 30, 2012
    Publication date: January 5, 2017
    Inventor: Swapan K. Ghosh
  • Patent number: 9531747
    Abstract: A transparent proxy for malware detection includes a monitor module, a protocol determination module, a challenge generation module, a response determination module, and a data control module. The monitor module examines data originating from an application towards a remote server. The protocol determination module identifies the protocol type used for the data. The challenge generation module produces a challenge for the application based upon the protocol type, sends the challenge to the application, and maintains a state related to the data and the challenge. The response determination module makes a determination if an automatic non-interactive application response is received in response to the challenge from the application. The data control module allows the first data to continue to the remote server when the determination is valid. The data control module reports malware detection and blocks the data to continue to the remote server when the determination is invalid.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: December 27, 2016
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Angelos Stavrou, Sushil Jajodia, Anup K. Ghosh, Rhandi Martin, Charalampos Andrianakis
  • Patent number: 9512099
    Abstract: Various embodiments of the present invention relate to, among other things, compounds that are inhibitors of Memapsin 1 and, as a result, are effective in the treatment of Alzheimer's disease or diabetes (e.g., Type 2 diabetes).
    Type: Grant
    Filed: September 12, 2014
    Date of Patent: December 6, 2016
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • Patent number: 9499558
    Abstract: Inhibitors of HIV-1 protease and compositions containing them are described. Use of the inhibitors and compositions containing them to treat HIV, AIDS, and AIDS-related diseases is described.
    Type: Grant
    Filed: April 21, 2015
    Date of Patent: November 22, 2016
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Bruno D. Chapsal, Hiroaki Mitsuya, Cuthbert D Martyr
  • Patent number: 9486294
    Abstract: A surgical system is disclosed. The surgical system can include a tray and a vacuum-fitted cover covering at least a portion of the tray. The surgical system can comprise a tray and a drape at least partially vacuum-fitted to the tray. A surgical drape is also disclosed. The surgical drape can comprise a cover including an opening and an interior cavity defined by a flexible wall which is configured to receive a support surface. The surgical drape can further comprise a closable portion configured to close the opening and seal at least a portion of the support surface within the interior cavity. The surgical drape can further include a valve in fluid communication with the interior cavity, wherein the valve is configured to enable the suction of air from the interior cavity and draw the flexible wall inwardly to closely envelop at least a portion of the support surface.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: November 8, 2016
    Inventor: Krishnan K. Ghosh
  • Patent number: 9487541
    Abstract: Tricylic ether carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are describes. Methods of using the disclosed compounds for treating patients infected with HIV are also described.
    Type: Grant
    Filed: October 8, 2013
    Date of Patent: November 8, 2016
    Assignees: Purdue Research Foundation, National University Corporation Kumamoto University
    Inventors: Arun K. Ghosh, Chun-Xiao Xu, Hiroaki Mitsuya, Garth Parham
  • Publication number: 20160297831
    Abstract: Embodiments of the present invention provide, among other compounds, a family of spliceosome-inhibiting compounds that can be used as therapeutic anti-cancer agents. The compounds are synthesized in a process that includes the catalytic cross metathesis of a cyclic epoxy alcohol to an amide.
    Type: Application
    Filed: November 19, 2014
    Publication date: October 13, 2016
    Inventor: Arun K. Ghosh
  • Patent number: 9446393
    Abstract: In some embodiments, the present disclosure pertains to a compound, comprising a transition metal complex having the formula ?-[M(x,y)-L1(w,v)-L2(t,u)-L3]p+An?mZ?p_m. In an embodiment of the present disclosure ? may be A. In another embodiment ? may be ?. In some embodiments of the present disclosure, M is a transition metal. In a related embodiment, p is an integer corresponding to the oxidation state of M. In some embodiments of the present disclosure, each of x, y, w, v, t, and u independently comprise R. In other embodiments, each of x, y, w, v, t, and u independently comprise S. In an embodiment of the present disclosure, each of L1, L2, and L3 independently is a ligand comprising a substituted diamine. In some embodiments, An? comprises a lipophilic anion, where m is from 1 to 3, and where Z? comprises an optional second anion.
    Type: Grant
    Filed: July 29, 2013
    Date of Patent: September 20, 2016
    Assignee: THE TEXAS A&M UNIVERSITY SYSTEM
    Inventors: Kyle G. Lewis, John A. Gladysz, Subrata K. Ghosh
  • Patent number: 9436822
    Abstract: An embodiment for providing a secure virtual browsing environment includes creating a virtual browsing environment with a virtualized operating system sharing an operating system kernel of a supporting operating system and executing the browser application within the virtual browsing environment. Another embodiment includes receiving a website selection within a browser application, determining if the website selection corresponds to a secure bookmark, and creating a second virtual browsing environment and executing the browser application within the second virtual browsing environment to access the website selection when the website selection corresponds to a website specified as a secure bookmark.
    Type: Grant
    Filed: September 9, 2014
    Date of Patent: September 6, 2016
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Anup K. Ghosh, Sushil Jajodia, Yih Huang, Jiang Wang
  • Publication number: 20160247615
    Abstract: A dipole-magnet system and method for producing high-magnetic-fields, including an open-region located in a radially-central-region to allow particle-beam transport and other uses, low-temperature-superconducting-coils comprised of low-temperature-superconducting-wire located in radially-outward-regions to generate high magnetic-fields, high-temperature-superconducting-coils comprised of high-temperature-superconducting-tape located in radially-inward-regions to generate even higher magnetic-fields and to reduce erroneous fields, support-structures to support the coils against large Lorentz-forces, a liquid-helium-system to cool the coils, and electrical-contacts to allow electric-current into and out of the coils. The high-temperature-superconducting-tape may be comprised of bismuth-strontium-calcium-copper-oxide or rare-earth-metal, barium-copper-oxide (ReBCO) where the rare-earth-metal may be yttrium, samarium, neodymium, or gadolinium.
    Type: Application
    Filed: February 11, 2016
    Publication date: August 25, 2016
    Inventors: RAMESH GUPTA, Ronald Scanlan, Arup K. Ghosh, Robert J. Weggel, Robert Palmer, Michael D. Anerella, Jesse Schmalzle
  • Patent number: 9393075
    Abstract: A surgical system is disclosed. The surgical system can include a tray and a vacuum-fitted cover covering at least a portion of the tray. The surgical system can comprise a tray and a drape at least partially vacuum-fitted to the tray. A surgical drape is also disclosed. The surgical drape can comprise a cover including an opening and an interior cavity defined by a flexible wall which is configured to receive a support surface. The surgical drape can further comprise a closable portion configured to close the opening and seal at least a portion of the support surface within the interior cavity. The surgical drape can further include a valve in fluid communication with the interior cavity, wherein the valve is configured to enable the suction of air from the interior cavity and draw the flexible wall inwardly to closely envelop at least a portion of the support surface.
    Type: Grant
    Filed: August 20, 2015
    Date of Patent: July 19, 2016
    Inventor: Krishnan K. Ghosh
  • Patent number: 9359317
    Abstract: Described herein are compounds, compositions, and methods for treating HIV and related diseases.
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: June 7, 2016
    Assignee: Purdue Research Foundation
    Inventor: Arun K. Ghosh
  • Patent number: 9346820
    Abstract: Various embodiments of the present invention relate to, among other things, compounds and methods of using those compounds to treat an HIV infection. The compounds of the various embodiments of the present invention provide, among other things, therapeutic agents having enhanced penetration capability across the blood-brain barrier, such that they can enter the CNS to treat an HIV-1 infection in the CNS.
    Type: Grant
    Filed: September 10, 2014
    Date of Patent: May 24, 2016
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Sofiya Yashchuk
  • Publication number: 20160140030
    Abstract: A method and associated system for automatically correcting an application based on runtime behavior of the application. An incident indicates a performance of the application in which a problem object produces an outcome that had not been expected by a user. An incident flow for the problem object is automatically analyzed. Actual run of the application renders a forward data flow and at least one backward data flow is simulated from an expected outcome of the problem object. The forward data flow and the at least one backward data flow are compared to create a candidate fault list for the problem object. A technical specification that corrects the incident by use of the candidate fault list and a specification of the application is generated.
    Type: Application
    Filed: January 22, 2016
    Publication date: May 19, 2016
    Inventor: Anup K. GHOSH
  • Patent number: 9342587
    Abstract: Embodiments of the present invention relate to an approach for reusing information/knowledge. Specifically, embodiments of the present invention provide an approach for retrieving previously stored data to satisfy queries (e.g., jobs/tickets) for solutions to problems while maintaining privacy/security of the data as well as ensuring the quality of the results. In a typical embodiment, a query for a solution to a problem is received and details are extracted therefrom. Using the details, a search is performed on a set of data stored in at least one computer storage device. Based on the search, a set of results will be generated and classified into a set of categories. In any event, the quality of each of the set of results will be assessed based on the usefulness of the set of results.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: May 17, 2016
    Assignee: International Business Machines Corporation
    Inventors: Anup K. Ghosh, Sugata Ghosal, Nandakishore Kambhatla, Rose C. Kanjirathinkal, Asidhara Lahiri, Debapriyo Majumdar, Shajith I. Mohamed, Karthik Visweswariah
  • Patent number: 9309213
    Abstract: C3-functionalized-cyclopentanyltetrahydrofuranyl carbamates that inhibit HIV proteolytic enzymes and processes for preparing the compounds are described. Compositions comprising the disclosed compound and methods of using the compounds and/or compositions for treating patients infected with HIV are also described.
    Type: Grant
    Filed: July 11, 2012
    Date of Patent: April 12, 2016
    Assignee: Purdue Research Foundation
    Inventors: Arun K. Ghosh, Hiroaki Mitsuya, Bruno D. Chapsal
  • Publication number: 20160089207
    Abstract: A surgical tray system is disclosed. The system includes a tray for use in an operating room environment. In various embodiments, the tray includes an indentation having a bowl shape. A vacuum sealed bag is fitted over the tray and form fitted to the tray when the air is removed from within the bag. The tray optionally includes an light source for illuminating an area under the tray, a magnification element, and pouches for storing items used during a surgical procedure. The tray is optionally substantially transparent to allow light to pass through the tray. The tray is ideally positioned over a patient bed. It may be mounted via an arm to a bed frame member, a monitor station, or a ceiling fixture.
    Type: Application
    Filed: December 9, 2015
    Publication date: March 31, 2016
    Inventor: Krishnan K. Ghosh
  • Patent number: 9280406
    Abstract: A method and associated system for automatically correcting an application based on runtime behavior of the application. An incident indicates a performance of the application in which a problem object produces an outcome that had not been expected by a user or by a ticketing tool. An incident flow for the problem object is automatically analyzed. Actual run of the application renders a forward data flow and at least one backward data flow is simulated from an expected outcome of the problem object. The forward data flow and the backward data flow(s) are compared to create a candidate fault list for the problem object. A technical specification to correct the candidate fault list and a solution to replace the application are subsequently devised.
    Type: Grant
    Filed: March 21, 2013
    Date of Patent: March 8, 2016
    Assignee: International Business Machines Corporation
    Inventor: Anup K. Ghosh
  • Patent number: 9270697
    Abstract: A hardware-assisted integrity monitor may include one or more target machines and/or monitor machines. A target machine may include one or more processors, which may include one or more system management modes (SMM). A SMM may include one or more register checking modules, which may be configured to determine one or more current CPU register states. A SMM may include one or more acquiring modules, which may be configured to determine one or more current memory states. A SMM may include one or more network modules, which may be configured to direct one or more communications, for example of one or more current CPU register states and/or current memory states, to a monitor machine. A monitor machine may include one or more network modules and/or analysis modules. An analysis module may be configured to determine memory state differences and/or determine CPU register states differences.
    Type: Grant
    Filed: August 22, 2014
    Date of Patent: February 23, 2016
    Assignee: George Mason Research Foundation, Inc.
    Inventors: Anup K. Ghosh, Kun Sun, Jiang Wang, Angelos Stavrou
  • Patent number: 9242233
    Abstract: Methods for preparing bound non-acidic germanium zeolite catalysts are disclosed, where the preparation is reproducible and scalable and where the catalysts have similar or the same activity and selectivities of a standard naphtha aromatization catalyst and methods for aromatizing naphtha.
    Type: Grant
    Filed: May 2, 2012
    Date of Patent: January 26, 2016
    Assignee: SAUDI BASIC INDUSTRIES CORPORATION
    Inventors: Ashim K. Ghosh, Scott A. Stevenson, Neeta Kulkarni, Mike Mier, Balamurali K. Nair, Dustin Farmer