Abstract: A percutaneous device for achieving hemostasis in a vessel, particularly a device for achieving hemostasis following the failure of a vascular closure device has a catheter with an attached inflation device. The catheter preferably has two different lumens, one for a guide wire and one for fluid used to inflate the inflation device. When inflated, the inflation device unfurls to block the puncture in the blood vessel. Distal blood flow continues uninterrupted with the device in the furled and unfurled state, preventing any issues distally from the puncture site.

Abstract: A method for the analysis of minimal residual disease is provided. In some embodiments, the method comprises obtaining multiple pairs of primers designed to amplify sequences that contain a plurality of sequence variations that have been previously identified in a patient's tumor. Amplicons are then obtained through a targeted multiplex amplification that amplifies those sequences from cell-free DNA isolated from a plasma sample. The amplicons are sequenced and two or more of the sequence variations are detected from sequence reads, wherein the detecting comprises comparing a quantity of sequence reads containing a sequence variation against a threshold value. A score is then calculated for the patient sample based on the combined allele frequencies of the detected two or more sequence variations, wherein the score indicates the presence of minimal residual disease.

Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for adjusting neural network resource usage. One of the methods includes receiving a network input for processing by a task neural network, the task neural network comprising a plurality of neural network layers; receiving a usage input specifying a respective weight for each of one or more usage factors, wherein each usage factor impacts how many computational resources are used by the task neural network during the processing of the network input; and processing the network input using the task neural network in accordance with the usage input to generate a network output for the network input, comprising: selecting, based at least on the usage input, a proper subset of the plurality of neural network layers to be active while processing the network input, and processing the network input using only the selected neural network layers.

Abstract: Compounds that inhibit HIF-2?, and compositions containing the compound(s) and methods for synthesizing the compounds, are described herein. Also described are the use of such compounds and compositions for the treatment of a diverse array of diseases, disorders, and conditions, including cancer- and immune-related disorders that are mediated, at least in part, by HIF-2?.

Abstract: The present invention is a system and method for the purchase of a physical athletic jersey and its associated NFT and how it could be implemented in both the physical world and the Metaverse. Within the Metaverse, the consumer's avatar wears the jersey and can attend virtual social events to increase the value and price of the NFT. Once the NFT is developed, it can be sold and licensed. Within the physical world, the NFT can be shown at participating venues for the consumer to receive promotions or discounts. Along with the physical jersey and NFT is a corresponding insurance policy, which ensures that if the player associated with the jersey and NFT is traded or switches teams, the consumer can receive either a new player's jersey on the same team or the original player's jersey on the new team.

Abstract: An apparatus for supporting a laundry hamper is disclosed. The apparatus comprises a supporting rod having one or more sides arranged to form a closed frame, one or more mounting brackets, and means for securing the mounting bracket to a door of a cabinet, such as a tilt-out cabinet. Each of the mounting brackets comprises a channel with a recess within which a portion of the supporting rod is inserted therein. The channel comprises a first channel segment and a second channel segment separated by a gap. Each of the first and second channel segments comprises a first side wall and an opposing second side wall integral with a bottom wall to define a generally U-shaped structure. The bottom wall of the first channel segment faces a side opposite from the side at which the bottom wall of the second channel segment faces. Aspects of the invention relate to a laundry hamper assembly comprising the apparatus and at least one laundry hamper being supported thereon.

Abstract: A crossing gate mechanism includes a swingable gate arm, a rotatable gate arm shaft fixed to the gate arm, and an electronic sensor assembly coupled to the gate arm shaft. Rotation of the gate arm shaft corresponds with swinging of the gate arm. The electronic sensor assembly senses an angular position of the gate arm shaft and transmits a position signal corresponding thereto. The electronic sensor assembly includes a driving element that is attached to the gate arm shaft to rotate therewith. the electronic sensor assembly also includes a driven element that is driven by the driving element such that rotation of the gate arm shaft causes the driven element to rotate. The electronic sensor assembly is configured to generate the position signal based on a position of the gate arm shaft.

Abstract: Apparatuses, methods, and systems for automated testing of templates of a mobile message. One method includes generating at least a first template of the mobile message and a second template of the mobile message, each of the first template and the second template having at least a different content or a different send time, assigning a respective group of mobile message recipients to the first template of the mobile message and the second template of the mobile message, determining automatically whether the first template of the mobile message has a statistical advantage over the second template of the mobile message through testing, and sending the mobile message of the first template to a remainder of the planned mobile message recipients when the first template of the mobile message is determined to have the statistical advantage over the second template of the mobile message.

Abstract: A method and system for operating a multitenancy telephony system including receiving a plurality of call requests associated with an application server; selecting a subset of the received call requests using a load balancer; assigning each selected call request to one of a plurality of resources creating, on the assigned resource, a call session for each selected call request; and coordinating the created call sessions resulting from the selected subset of the received call requests associated with the application server.

Abstract: The systems and methods provide a container assembly comprising: a container having a known storage capacity for storing a liquid; an additive dispensing assembly, the additive dispensing assembly dispensing variable, non-zero quantities of one or more additives into the liquid stored in the container; one or more vessels that each contain one of the additives, of the one or more additives, to be dispensed into the liquid; and a gas dispensing assembly, the gas dispensing assembly releasing a gas into the liquid stored in the container, and the gas dispensing assembly including: an onboard gas tank; a valve assembly; and a gas outlet, and the valve assembly controlling flow of gas from the onboard gas tank, through the valve assembly, and to the gas outlet so as to output the gas into the liquid; and wherein the valve assembly, to perform the controlling the flow of gas, is movable between: an open position, in which flow of gas is allowed to flow from the onboard gas tank to the gas outlet; and a closed posi

Abstract: The present invention relates to compounds that inhibit Son of sevenless homolog 1 (SOS1) activity. In particular, the present invention relates to compounds, pharmaceutical compositions and methods of use, such as methods of treating cancer using the compounds and pharmaceutical compositions of the present invention.

Abstract: A crossing gate mechanism includes a gate mechanism enclosure, electrical components inside the gate mechanism enclosure, and a controller inside the gate mechanism enclosure. The controller is connected to and configured to monitor and/or control the electrical components. The controller includes an operator panel for receiving input from a user. In addition, the controller has a user interface displayed by the operator panel. The controller is operable to present information associated with the electrical components on the user interface.

Abstract: A method of decreasing conversion of nicotine to nornicotine is provided herein. The methods includes administering at least one basic region/leucine zipper (bZIP) type transcription factor inhibitor to an organism in need thereof. Also provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a bZIP type transcription factor binding site on a promoter of a nicotine N-demethylase (NND). Further provided herein is a method of decreasing conversion of nicotine to nornicotine including mutating a plant genome to knockout at least one bZIP type transcription factor.

Abstract: Systems and methods for measuring a cleave angle of an optical fiber using a cleave angle measurement system is provided herein. In an aspect, a method for measuring a cleave angle of an optical fiber may include providing a cleave angle measurement system. The cleave angle measurement system may include an optical fiber channel, an image sensor, and a light source. The method may include placing an optical fiber having a cleaved end into the optical fiber channel. The method may include determining an optical center of the image sensor. The method may include reflecting light transmitted by the light source off of the cleaved end of the optical fiber and detecting, by the image sensor, light reflected off of the cleaved end of the optical fiber. The cleave angle of the optical fiber may be determined based on the light reflected off of the cleaved end.

Abstract: An apparatus for treating a biological fluid, comprising a plurality of filtration devices. In some embodiments, each of the plurality of filtration devices comprising at least one inlet and at least one outlet; and a first insert plate and a second insert plate opposite the first insert plate, wherein the plurality of filtration devices is disposed therebetween. In some embodiments, each filtration device has a vent port. A manifold for each of the inlets, outlets, and vent ports is optionally fluidly connected. In another embodiment, hose barb connectors or the like may be protected from damage and/or exposure by being recessed in the device or positioned at a periphery of the device. Embodiments include apparatus and methods to achieve dripless connect/disconnect and to reduce the number of sterile-to-sterile connections.

Abstract: A raising assembly for use with a gangway connected for rotation between a raised stowed position and a lowered deployed position. The raising assembly comprises at least one fluid actuated cylinder connected to the gangway. A raising actuator is operative to cause operation of the cylinder in a manner that rotates the gangway toward the stowed position while the raising actuator is continuously activated by an operator. A lowering actuator is operative to cause operation of the cylinder in a manner that rotates the gangway toward the deployed position due to gravitational forces while the lowering actuator is continuously activated by the operator. The raising assembly is configured to maintain the gangway at a current position between the stowed position and the deployed position if the operator does one of ceasing to activate the raising actuator while raising the gangway or ceasing to activate the lowering actuator while lowering the gangway.

Abstract: Systems and methods for aligning an optical fiber are provided herein. The method may include providing an optical fiber having a first end and a second end, where the first end of the optical fiber has a predefined manufacturing property. For example, the predefined manufacturing property of the first end of the optical fiber may include a predefined cleave angle. The method may also include positioning the optical fiber such that the first end of the optical fiber faces a microlens array (MLA) alignment system. In an example embodiment, the MLA alignment system may include a tilt sensing device and a position sensing device. The method may also include emitting a light beam from the first end of the optical fiber toward the MLA alignment system.

Abstract: The method, system, and computer-readable medium facilitate a fast rental application. The fast rental application includes a set of data corresponding to a user profile that is pertinent to a rental application. The data corresponding to the user profile can be retrieved from one or more databases and also received via a client device in a computer network. The data can be analyzed and stored as part of the profile in a profile repository and then transmitted to an property manager recipient.

Abstract: A simplified, compact, recliner mechanism is provided which can be adapted to many types of recliner design. A front linkage assembly and a rear linkage assembly provide the desired movement of the seat and back when moving from the TV position to the fully reclined position, obviating the need for a track and roller design. Moreover, a front pivot link and a rear pivot link are provided and oriented in a manner that allows the desired forward seat movement as the recliner moves from the closed position to the TV position. The geometries of the front linkage assembly, the rear linkage assembly, the front pivot link and the rear pivot link allow a slim profile design allowing great flexibility in the design of the recliner.