Abstract: The disclosed subject matter relates to a system and method for personalizing customer experience at a retailer's physical location in order to increase sales and customer satisfaction. The personalization is based upon classification of customer's online interaction with the retailer. Upon detecting the customer's presence at the retailer's physical location, data of the customer's online interactions is retrieved and classified based on the type of online interactions and temporal characteristics. Push content is transmitted to the customer, the push content being based upon at least the classification and data associated with retailer's physical location.

Abstract: The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.

Abstract: The invention relates to iRNA, e.g., double-stranded ribonucleic acid (dsRNA), compositions targeting the complement component C5 gene, and methods of using such iRNA, e.g., dsRNA, compositions to inhibit expression of C5 and to treat subjects having a complement component C5-associated disease, e.g., paroxysmal nocturnal hemoglobinuria.

Abstract: The present invention is a fully automated, AI-based smart restaurant system that leverages the power of Cloud Native IoT AIOS to revolutionize the food service industry. This system integrates IoT appliances within the kitchen to create a connected and intelligent ecosystem that optimizes food preparation processes and guarantees consistent quality. The AIOS fully automates all kitchen tasks and processes, including ordering, ingredient tracking, and inventory management, resulting in maximum efficiency and minimal resource consumption. With the AIOS running the show, there is no need for manual labor, making the restaurant a completely contactless experience. The AIOS monitors and regulates food preparation processes to minimize the risk of food contamination and other health hazards, ensuring a safe dining experience for customers.

Abstract: The present invention provides a phosphorothioate-modified oligonucleotide comprising a structure shown below: The present invention also provides a phosphorothioate-modified oligonucleotide comprising a structure having formula (CIII):

Abstract: Various arrangements are presented that involve an automated shutter control system being used with a separate and distinct video camera. The automated shutter control system can include a shutter, a shutter motor, power sensing circuitry that measures an amount of power being supplied to the electronic display, and a processing system. The processing system controls the shutter motor that causes the shutter to be actuated to an open position or a closed position based on the amount of power being supplied to the electronic display as measured by the circuitry of the power sensing circuitry.

Abstract: Various arrangements are presented that involve an automated shutter control system being used with a separate and distinct video camera. The automated shutter control system can include a shutter, a shutter motor, power sensing circuitry that measures an amount of power being supplied to the electronic display, and a processing system. The processing system controls the shutter motor that causes the shutter to be actuated to an open position or a closed position based on the amount of power being supplied to the electronic display as measured by the circuitry of the power sensing circuitry.

Abstract: This disclosure relates to an improved process for the preparation of carbohydrate conjugates. The disclosure also relates to carbohydrate conjugated iRNA agents comprising these carbohydrate conjugates, which have improved purity and are advantageous for the in vivo delivery of the iRNA agents.

Abstract: Aerodynamically mistuned airfoils for unsteady loss reductions are disclosed herein. An example apparatus disclosed herein includes a disk, a first airfoil coupled to the disk, the first airfoil having a first geometry, and a second airfoil coupled to the disk adjacent to the first airfoil, the second airfoil having a second geometry different than the first geometry, the first airfoil and the second airfoil produce non-uniform wake passing times during operation of the disk.

Abstract: The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.

Abstract: Provided are a system, method, and computer program product for an account-to-account transaction network. The method includes receiving, via a first application programming interface (API), a transaction request for a transaction including a transaction amount, an issuer identifier, and a merchant identifier. The method includes determining an issuer uniform resource locator (URL) based on the issuer identifier, generating an intent identifier associated with the transaction request, and transmitting the issuer URL and the intent identifier via the first API. The method includes transmitting the intent identifier, the transaction amount, and the merchant identifier to an issuer system associated with the issuer identifier via a second API.

Abstract: The present invention provides lipids that are advantageously used in lipid particles for the in vivo delivery of therapeutic agents to cells. In particular, the invention provides lipids having the following structure wherein: R1 and R2 are each independently for each occurrence optionally substituted C10-C30 alkyl, optionally substituted C10-C30 alkenyl, optionally substituted C10-C30 alkynyl, optionally substituted C10-C30 acyl, or -linker-ligand; R3 is H, optionally substituted C1-C10 alkyl, optionally substituted C2-C10 alkenyl, optionally substituted C2-C10 alkynyl, alkylhetrocycle, alkylphosphate, alkylphosphorothioate, alkylphosphorodithioate, alkylphosphonates, alkylamines, hydroxyalkyls, ?-aminoalkyls, ?-(substituted)aminoalkyls, ?-phosphoalkyls, ?-thiophosphoalkyls, optionally substituted polyethylene glycol (PEG, mw 100-40K), optionally substituted mPEG (mw 120-40K), heteroaryl, heterocycle, or linker-ligand; and E is C(O)O or OC(O).

Abstract: A system and computer-implemented method for authenticating digital transactions. The method includes receiving a device registration request and a device attestation response including at least a device integrity status from a device. In response to the device registration request, the method includes providing a device registration response to the device, based on validation of the device integrity status. Further, the method includes receiving a first payment transaction request and an enrolment request from the device via an application to authenticate a second payment transaction request using a first type of authentication technique. Finally, the method includes enrolling the device to the first type of authentication technique and providing a second token to the device based on a result of the first payment transaction request, wherein the second token is used for authenticating the second payment transaction request.

Abstract: The embodiments herein provide a Crystalline Strontium Titanate (STO) and a method for deposition of the STO on a silicon substrate. The embodiments herein utilize radio-frequency (RF) magnetron sputtering to grow crystalline pure phase Strontium Titanate SrTiO3 (STO) with single orientation upon a surface of oriented Silicon (Si) substrates followed by annealing at 800° C. for 1 hour in ambient conditions. Furthermore, the embodiments herein completely eliminates the buffer layer which is generally needed beneath the STO thin films, making the deposition of STO films on silicon substrates much more cost-effective than the existing method. Hence a single crystal STO film is directly obtained on the silicon substrate at the end of the process.

Abstract: Some embodiments provide a method for quantifying quality of several service classes provided by a link between first and second forwarding nodes in a wide area network (WAN). At a first forwarding node, the method computes and stores first and second path quality metric (PQM) values based on packets sent from the second forwarding node for the first and second service classes. The different service classes in some embodiments are associated with different quality of service (QoS) guarantees that the WAN offers to the packets. In some embodiments, the computed PQM value for each service class quantifies the QoS provided to packets processed through the service class. In some embodiments, the first forwarding node adjusts the first and second PQM values as it processes more packets associated with the first and second service classes. The first forwarding node also periodically forwards to the second forwarding node the first and second PQM values that it maintains for the first and second service classes.

Abstract: Aspects of the disclosure relate to upgrading an application within a simulated version of an enterprise system to detect and correct potential errors as a result of the upgrade. A computing platform may create a simulated version of the enterprise system by receiving metadata associated with the enterprise system, and converting the metadata into system parameters. Virtual parameters may be created by the computing system based on upgrading an application within the simulated version of the enterprise system. The computing system may create system nodes and virtual nodes. The system nodes and virtual nodes may be dynamically linked in order to determine errors caused by the application upgrade within the simulated version of the enterprise system. The computing platform may determine actions to correct the errors and input the results and feedback into an AI engine to further refine the accuracy and reliability of the computing platform over time.

Abstract: Techniques are disclosed for measuring a concentration of an analyte in a subject based on reflectance spectra obtained from the subject. The spectra are obtained while and/or before and/or after photoreactions are induced in the subject, where the photoreactions change the reflectivity of the subject. The rate of change of the reflectivity is correlated with the concentration of the analyte.

Abstract: Aspects of the disclosure relate to upgrading an application within a simulated version of an enterprise system to detect and correct potential errors as a result of the upgrade. A computing platform may create a simulated version of the enterprise system by receiving metadata associated with the enterprise system, and converting the metadata into system parameters. Virtual parameters may be created by the computing system based on upgrading an application within the simulated version of the enterprise system. The computing system may determine errors caused by the application upgrade within the simulated version of the enterprise system based on differences between the system parameters and the virtual parameters. The computing platform may determine actions to correct the errors and input the results and feedback into an AI engine to further refine the accuracy and reliability of the computing platform over time.

Abstract: An electrical connector assembly terminal modules configured to contain electrical terminals connected to one or more electrical cables, an inner module frame in which terminal modules are secured, and an outer housing having cantilevered locking arms with primary surfaces and secondary surfaces on inner sides of the locking arms to secure the inner module frame to the female outer housing. Latch surfaces of the inner module frame engage the primary surfaces when the inner module frame is inserted within the female outer housing. The female outer housing receives a header having side walls surrounding mating electrical terminals. The locking arms define ramp features on outer sides of the locking arms that push the locking arms inwardly when the side walls contact the ramp features of the locking arms as the header is inserted within the outer housing. A method of assembling such an electrical connector is also provided.

Abstract: Disclosed herein are lipid compositions comprising a cationic lipid of formula (I), a neutral lipid, a sterol and a PEG or PEG-modified lipid, wherein formula (I) is (F). Also disclosed are methods of producing the cationic lipid of formula (I).