Abstract: The system comprises a FL-based generative adversarial network (GAN) for generating adversarial examples, wherein the GAN includes a generator for generating the adversarial examples and a discriminator for distinguishing the adversarial examples from the original data, wherein the FL network includes multiple clients, each having a local dataset and a local DNN model, and a central server for coordinating the training process; a DNN for classifying data, where the DNN is trained using the generated adversarial examples, wherein the training process includes exchanging the model updates between the client’s server and the central server; an evaluation module for measuring the adversarial accuracy and adversarial robustness of the DNN using appropriate metrics, including the adversarial accuracy, the adversarial loss, and the robustness to perturbations; and an adjustment module for adjusting the architecture or parameters of the DNN based on the evaluation results to improve its adversarial robustness.

Abstract: Aerodynamically mistuned airfoils for unsteady loss reductions are disclosed herein. An example apparatus disclosed herein includes a disk, a first airfoil coupled to the disk, the first airfoil having a first geometry, and a second airfoil coupled to the disk adjacent to the first airfoil, the second airfoil having a second geometry different than the first geometry, the first airfoil and the second airfoil produce non-uniform wake passing times during operation of the disk.

Abstract: A cloud-based platform may receive an indication of one or more event associated with a service provider and modify a configuration associated with providing a schedule of respective service appointments offered by the service provider based on the indication of the one or more events. The cloud-based platform may then receive a request for a new service appointment after modifying the configuration and in response to receiving the request for the new service appointment, determine a number of scheduled appointments associated with a first time window, determine whether the number of scheduled appointments is less than a maximum number of appointments associated with the first time window, and automatically schedule the new service appointment during the first time window in response to determining that the number of scheduled appointments is less than the maximum number of appointments associated with the first window.

Abstract: Water filtration systems are disclosed. The water filtration systems include a regenerative media filter vessel comprising a housing, an inlet, and an outlet, a diffuser fluidly connected to the inlet and disposed within the regenerative media filter vessel, and at least one pump configured to direct water through the water filtration system. The housing of the regenerative media filter vessel comprises a concave lower portion centered about a vertical axis of the vessel. The position of the diffuser along a height of the regenerative media filter vessel is determined by at least a ratio of the height to an inner diameter of the regenerative media filter vessel and a radius of curvature of the concave lower portion. A regenerative media filter including a diffuser having asymmetrically spaced apertures is also disclosed.

Abstract: A stabilization control system for a saddled vehicle including: a vehicle roll angle data unit including a predetermined roll angle of the vehicle; a comparator unit that is configured to receive inputs from the vehicle roll angle data unit and a feedback roll angle data unit and is configured to determine a difference roll angle data between the inputs from the vehicle roll angle data unit and the feedback roll angle data unit; a stabilization control unit that is configured to receive the difference roll angle data from the comparator unit and is configured to enable an actuator driver based upon the difference roll angle data received; and one or more vehicle sensors that are configured to provide inputs to the stabilization control unit.

Abstract: The present invention relates to a multipurpose and long endurance Hybrid Unmanned Aerial Vehicle (HUAV) with the combined functions of a Vertical Take-off and Landing (VTOL) and a fixed wing operation. The HUAV may take-off and land vertically on both land and water, and perform a mid-air transition from a VTOL mode to a fixed wing mode. The HUAV includes an airframe, a fixed wing unit having at least one forward thrust motor, one or more VTOL units mounted on a tail boom, and a fuselage of the airframe. Each of the one or more VTOL units includes at least one VTOL motor, and a control unit configured to control on-board transition of the HUAV between the VTOL mode and the fixed wing mode by controlling at least one forward thrust motor and at least one VTOL motor.

Abstract: One aspect of the present invention relates to double-stranded RNA (dsRNA) agent capable of inhibiting the expression of a target gene. The antisense strand of the dsRNA molecule comprises at least one thermally destabilizing nucleotide occurring at a seed region; the dsRNA comprises at least four 2?-fluoro modifications, and the sense strand of the dsRNA molecule comprises ligand, wherein the ligand is an ASGPR ligand. Other aspects of the invention relate to pharmaceutical compositions comprising these dsRNA molecules suitable for therapeutic use, and methods of inhibiting the expression of a target gene by administering these dsRNA molecules, e.g., for the treatment of various disease conditions.

Abstract: One aspect of the present invention relates to a small circular interfering RNA (sciRNA) comprising a sense strand and an antisense strand, each of said sense and antisense strands comprising at least one nucleic acid modification, optionally wherein the sense strand has a circular or substantially circular structure. Other aspects of the invention relate a pharmaceutical composition and a method for inhibiting the expression of a target gene in a subject using the sciRNA.

Abstract: The present invention relates to a cationic lipid having one or more biodegradable groups located in a lipidic moiety (e.g., a hydrophobic chain) of the cationic lipid. These cationic lipids may be incorporated into a lipid particle for delivering an active agent, such as a nucleic acid. The invention also relates to lipid particles comprising a neutral lipid, a lipid capable of reducing aggregation, a cationic lipid of the present invention, and optionally, a sterol. The lipid particle may further include a therapeutic agent such as a nucleic acid.

Abstract: The invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.

Abstract: An electrical connector assembly includes a connector body defining a terminal cavity in which an electrical terminal is received which has a flexible primary terminal lock arm configured to secure the terminal within the cavity and which has a tab extending from a free end of the primary terminal lock arm. The assembly further includes an independent secondary lock (ISL) defining a window therein, attached to the connector body, and movable from a pre-staged position to a staged position. The tab of the primary terminal lock arm is received within the window when the primary terminal lock arm is in an unflexed condition when the ISL is in the staged position. The tab and window cooperate to inhibit flexing of the primary terminal lock arm when the ISL is in the staged position. Alternatively, the primary terminal lock arm may define the window and the ISL may define the tab.

Abstract: The system comprises an image acquisition device for collecting medical images; an image pre-processing device for enhancing the visual quality; an image segmentation device for extracting the region of interest from the image’s background by identifying each image’s pixel characteristics, and dividing the image into segments; a feature extraction and selection device for extracting a set of features and selecting the optimized features; a model training device for training a fuzzy logic-based prediction model and a plurality of diagnosis-specific treatment response models to predict treatment response; and a central processing device coupled to a user input device for receiving a subject patient dataset including features obtained for a reduced feature dataset and comparing the subject patient dataset to a feature data scheme for predicting a response for the subject patient thereby predicting the diseases in its early stage.

Abstract: A method includes identifying a search term and obtaining historical data indicative of a number of times a game was selected from search results corresponding to search queries using the search term and indicative of a number of times the selected game was played by one or more users for at least a threshold amount of time. The method further includes generating a score based on the historical data. The score is associated with the search term and the selected game.

Abstract: Some embodiments provide a method for quantifying quality of several service classes provided by a link between first and second forwarding nodes in a wide area network (WAN). At a first forwarding node, the method computes and stores first and second path quality metric (PQM) values based on packets sent from the second forwarding node for the first and second service classes. The different service classes in some embodiments are associated with different quality of service (QoS) guarantees that the WAN offers to the packets. In some embodiments, the computed PQM value for each service class quantifies the QoS provided to packets processed through the service class. In some embodiments, the first forwarding node adjusts the first and second PQM values as it processes more packets associated with the first and second service classes. The first forwarding node also periodically forwards to the second forwarding node the first and second PQM values that it maintains for the first and second service classes.

Abstract: Methods, apparatus, and processor-readable storage media for automated compliance processing for cloud applications are provided herein. An example computer-implemented method includes detecting multiple cloud applications deployed across one or more data center-based cloud platforms comprising multiple geographic locations; identifying, for each of at least a portion of the multiple detected cloud applications, a set of executable programs carrying out runtime support on the cloud application; processing information pertaining to one or more forms of compliance for each of the at least a portion of the multiple detected cloud applications by comparing each identified set of executable programs with one or more pre-approved sets of executable programs; and performing one or more automated actions based at least in part on results of the comparing of each identified set of executable programs with one or more pre-approved sets of executable programs.

Abstract: Some embodiments of the invention provide, for a network manager of a secure SD-WAN (software-defined wide-area network), a method of securely adding an edge device, which operates at a branch location in a public network, to the SD-WAN. The method provides, to an activation service hosted on the public network, a record for the edge device that is to be added to the SD-WAN securely, the record for use by the activation service to authenticate the edge device. The method receives a first notification from the activation service indicating the edge device has been authenticated. The method receives a second notification from a verification service indicating the authenticated edge device has been verified. Based on the first and second notifications, the method provides to the activation service (i) a set of configuration data for the edge device and (ii) a set of authentication data for the edge device.

Abstract: Flow diverters for installation in mid-turbine frame systems at a conduit outlet of gas turbine engines are described. The flow diverters include a diverter body having a connector portion defining a diverter inlet, a diverter extension at least partially defining a diverter outlet, and a curved portion arranged between the connector portion and the diverter extension, the curved portion configured to change a direction of flow from a first direction to a second direction that is about 90° from the first direction as the flow passes from the diverter inlet to the diverter outlet.

Abstract: Some embodiments provide a method for quantifying quality of several service classes provided by a link between first and second forwarding nodes in a wide area network (WAN). At a first forwarding node, the method computes and stores first and second path quality metric (PQM) values based on packets sent from the second forwarding node for the first and second service classes. The different service classes in some embodiments are associated with different quality of service (QoS) guarantees that the WAN offers to the packets. In some embodiments, the computed PQM value for each service class quantifies the QoS provided to packets processed through the service class. In some embodiments, the first forwarding node adjusts the first and second PQM values as it processes more packets associated with the first and second service classes. The first forwarding node also periodically forwards to the second forwarding node the first and second PQM values that it maintains for the first and second service classes.