Abstract: A hydraulic tensioning system is associated with a wire rope feed system of a drilling rig for applying tension to the hoist and pulldown ropes during hoist and pulldown operations. The hydraulic tensioning system includes a hydraulic tensioning circuit with a hoist hydraulic circuit directing hydraulic fluid to a hoist actuator applying tension to the hoist wire rope and a pulldown hydraulic circuit directing hydraulic fluid to a pulldown hydraulic actuator applying tension to a pulldown wire rope. A hydraulic control valve can selectively direct flow to the hoist and pulldown hydraulic circuits.

Abstract: A catheter assembly is provided having a working lumen and a guide. The guide is configured to position a fragmentizing device within the working lumen. The guide is configured to prevent or minimize any unintended movement of a distal section of the fragmentizing device within the working lumen when the distal section of the fragmentizing device is positioned at a distal end of the working lumen.

Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.

Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.

Abstract: The present disclosure describes a system with a power management device, a wakeup circuit, a battery management device, and a connector. During a powered down mode of operation, the battery management device can provide, via the connector, a bias voltage to the wakeup circuit. In response to a wakeup switch being activated, the battery management device can provide a power supply (e.g., from a battery) to the power management device. Benefits of the wakeup circuit include (1) a reduction of battery consumption—and thus improving battery lifetime—when the electronic system is in a powered down mode of operation because the wakeup circuit has lower number of active components compared to other designs and (2) a non-complex wakeup circuit design because one or more existing connector interconnects between the power management device and the battery management device can be re-used during electronic system's powered down mode of operation.

Abstract: Described herein are compounds that are HSD17B13 inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in the treatment of conditions, diseases, or disorders associated with HSD17B13 activity.

Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.

Abstract: Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.

Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.

Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.

Abstract: Described herein are compounds that are semicarbazide-sensitive amine oxidase (SSAO) inhibitors, methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds in treating or preventing a liver disease or condition.

Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.

Abstract: A sentry-post bollard has one or more divergent photo eye units mounted pivotally within the bollard which emit their beams horizontally and across the width the doorway of a high-speed industrial door or other motorized door. The sentry-post bollard may be used to open the door, hold it open, or both, when a vehicle or person is detected approaching the doorway. The sentry-post bollard may be used as a safety device throughout a facility. Placed at intersections, dock doors, ramp doors, etc., a safety beacon or siren can be activated to warn pedestrians of oncoming motorized traffic. The photo eye units project their beam(s) through a window slot extending circumferentially along the bollard and having a width of a nominal three-quarter inch.

Abstract: Some embodiments include compositions and methods of using or identifying compounds that modulate the activity of the granulocyte colony-stimulating factor receptor (GCFR). Some embodiments include use of compounds to treat certain disorders, such as hematopoietic or neurological disorders.

Abstract: In an embodiment, a system includes a power management unit (PMU), a non-volatile memory, a volatile memory, and a processor. The PMU may be configured to generate a power supply voltage, change a state of a status signal responsive to an event, and reduce a voltage level of the power supply voltage responsive to a predetermined period of time elapsing from detecting the event. The system may be configured to transition from a first to a second operating mode responsive to the change of the state of the status signal, and cancel pending commands to the non-volatile memory responsive to the transition to the second operating mode. The non-volatile memory may be configured to complete active commands prior the predetermined period of time elapsing.

Abstract: The present embodiments relate to compounds with physiological effects, such as the activation of hematopoietic growth factor receptors. The present embodiments also relate to use of the compounds to treat a variety of conditions, diseases and ailments such as hematopoietic conditions and disorders.

Abstract: Systems and methods consistent with the present disclosure include techniques for dynamic system performance tuning (DSPT). Techniques for DSPT include identifying an active software application during a user session and applying an application-specific profile that defines different system-hardware operating states of a computing system to enhance the performance of the active software application.

Abstract: A vapour barrier pan for use in building structures is provided. The pan is shaped to fit into the joist pocket located between subsequent joists of buildings. The pan central body comprises a top edge, two sides joined to the top edge generally perpendicularly, and a bottom edge joined to the two sides and parallel to the top edge. A centre crease is situated in between the two sides and extends from the top edge to the bottom edge. The centre crease instills flexibility into the pan body allowing it to be bent in order to fit into joist pockets of varying sizes. Alternatively, the pan can be cut along the centre crease separating it into two portions that can be overlapped to cover small joist pockets. The top edge and sides comprise flanges that extend outwardly in the same direction, with the flange for the top edge having a slit corresponding to the centre crease. Below the central body is a tab that can be situated under or over insulation installed in between wall studs under the joist pocket.

Abstract: A method for identifying candidate advocates for an organization includes obtaining a plurality of responses to a questionnaire completed by respective respondents based on transactions with the organization in which the questionnaire comprises a primary question and a plurality of secondary questions each having an ordered list of answer choices, calculating a respective correlation coefficient for each secondary question between the answer choices selected for the secondary question and the primary question in the plurality of responses, defining a criteria for assessing the responses to identify candidate advocates from the respondents that specifies, for a set of the secondary questions for which the respective correlation coefficients are greater than a threshold value, which answer choices for the set of secondary questions can be selected in a given response to satisfy the criteria, and identifying the respective respondent for each response that satisfies the criteria as a candidate advocate.