Abstract: A system for signal processing comprising a cyclic analog to digital converter structure having a first stage and a second stage, wherein the first stage is configured to receive an input signal to perform 1.5 bits/stage ADC and to generate a first stage output signal, and the second stage is configured to receive the first stage output signal and to perform fine offset tuning using a final conversion phase. The second stage further configured to perform 1.5 bits/stage ADC and to generate a second stage output that is fed back to the first stage to iteratively generate a next 1.5 bits, until (N?3) most significant bits of N bits of data are generated. A third stage configured to generate a three least significant bits of the N bits of data using a flash ADC sampling circuit that samples a residue signal at the output of the first stage.

Abstract: The present invention relates to certain novel shRNA molecules and methods of use thereof. According to certain embodiments of the present invention, methods for reducing the expression level of a target gene are provided. Such methods generally comprise providing a cell with one or more precursor nucleic acid sequences that encode two or more RNA molecules. A first RNA molecule comprises a double stranded sequence, which includes a guide strand sequence that is complementary to a portion of an mRNA transcript encoded by the target gene. In addition, a second RNA molecule comprises a second double stranded sequence, which includes a second guide strand sequence that is partially complementary to a portion of the mRNA transcript encoded by the target gene. Preferably, the second guide strand sequence comprises one or more bases that are mismatched with a nucleic acid sequence of the mRNA transcript encoded by the target gene.

Abstract: Intervertebral implants for implanting into an intervertebral space are provided. The implants can comprise one or more layers that are operably attached to one another. An implant can comprise a first layer having a first mating surface that mates with a second mating surface of a second layer. The first mating surface and the second mating surface can have features that allow them to complement each other. The implants can include one or more bore holes for receiving a fixation member. The bore holes can be horizontal, vertical or diagonal. In some cases, the bore holes will be blind bore holes.

Abstract: Compositions for use in microelectronic applications: Ra comprises one or more multiple bonds, provided that, if Ra comprises more than one multiple bond, these multiple bonds are not in a conjugated configuration; and R1, R2, R3 are independently selected from alkoxyl, hydroxyl, halide, OC(O)R, OC(O)OR, wherein R is alkyl or a substituted alkyl; and Rb is selected from H or a saturated group comprising alkyl, alkylene, or alkylidene; and R4, R5, R6 are independently alkoxyl, hydroxyl, halide, OC(O)R, OC(O)OR, wherein R is alkyl or a substituted alkyl; and Rc comprises more than one multiple bond, and these multiple bonds are in a conjugated configuration; and R7, R8, R9 are independently alkoxyl, hydroxyl, halide, OC(O)R, OC(O)OR, wherein R is alkyl or a substituted alkyl; and R10, R11, R12, R13 are independently alkoxyl, hydroxyl, halide, OC(O)R, OC(O)OR, wherein R is alkyl or a substituted alkyl.

Abstract: Certain aspects of the present disclosure relate to techniques for improving a circuit-switched fallback (CSFB) user experience. In aspects, methods and systems for autonomously returning a user equipment (UE) from a 2G (2nd generation)/3G (3rd generation) network to an LTE (Long Term Evolution) network are provided. The UE may store a flag to note whether a current circuit switched (CS) call in the 2G/3G network is a result of a CSFB. The UE, in response to detecting a termination of the current CS call in the 2G/3G network and determining that the terminated call was a CSFB call (e.g., from the status of the flag), may trigger a mobility mechanism to autonomously return the UE to the LTE network.

Abstract: An embodiment of the disclosed DHM system includes a light source configured to emit coherent optical waves, a first optical Fourier element configured to Fourier transform the optical waves from the object area, wherein the Fourier transform occurs at a Fourier plane and the optical waves from the object area includes directly transmitted waves and diffracted waves, a phase modulator at the Fourier plane configured to introduce a phase delay between the directly transmitted waves and the diffracted waves, a second optical Fourier element configured to receive the directly transmitted waves and the diffracted waves from the phase modulator and to inversely Fourier transform the directly transmitted waves and the diffracted waves to provide interfered optical waves, and at least one imaging device configured to record the interfered optical waves at two image planes to generate a first interferogram and a second interferogram.

Abstract: Disclosed are flexible polyamines, flexible amine-terminated polyformal adducts, flexible-amine-terminated polythioether adducts, compositions comprising flexible polyamines and isocyanate-terminated prepolymers, and compositions comprising flexible amine-terminated adducts and isocyanate-terminated prepolymers. Uses of the compositions as sealants, and particularly as aerospace sealants, are also disclosed.

Abstract: Methods and nodes are disclosed for the support of traffic protection and recovery in mesh networks having multiple nodes communicating via communication links. The problem of timely and reliable Shared Mesh Protection message delivery is addressed through creation of protocols and encoding of Shared Mesh Protection messages within an overhead of the optical data unit container, and by processing the Shared Mesh Protection messages by intermediate nodes of the mesh network. Thus, the Shared Mesh Protection messages are transmitted through the data plane with the transmission of user data.

Abstract: A bilirubin measuring apparatus includes a sample holding portion for holding at least a sample to be analyzed, a light source for directing light toward the sample holding portion, and means for determining a concentration of bilirubin in the sample based on an amount which the light is refracted while passing through the sample holding portion when at least the sample is held at the sample holding portion. Also, a method of measuring bilirubin in a sample includes holding at least the sample at a sample holding position, directing light toward the sample holding position so that the light will pass through the sample, and determining a concentration of bilirubin in the sample based on an amount which the light is refracted while passing through the sample holding position.

Abstract: A composition comprising: A) polymer that comprises: L is CX—CYZ, where X, Y, and Z are independently hydrogen, an alkyl, or a substituted alkyl; and, M is an alkylene, an arylene, a substituted alkylene, a substituted arylene, or C(O)O—W—, where W is an alkylene or a substituted alkylene; and R?, R?, and R?? are independently selected from an aromatic hydrocarbon, an aliphatic hydrocarbon, or a substituted hydrocarbon that comprises one or more of O, N, S, or Si atoms, provided that at least one of R?, R?, and R?? is selected from alkoxyl, aryloxyl, hydroxyl, halide, carboxyl, or carbonate; and, p is from 1 to 10,000; and the polymer does not comprise a polyhedral oligomeric silsesquioxane structure; and B) a polymer formed from a composition comprising at least one Si-containing compound as described herein. Compositions are suitable for microelectronic applications, and have improved adhesion to photoresists polymers.

Abstract: Intervertebral implants for implanting into an intervertebral space are provided. The implants can comprise one or more layers that are operably attached to one another. An implant can comprise a first layer having a first mating surface that mates with a second mating surface of a second layer. The first mating surface and the second mating surface can have features that allow them to complement each other. The implants can include one or more bore holes for receiving a fixation member. The bore holes can be horizontal, vertical or diagonal. In some cases, the bore holes will be blind bore holes.

Abstract: A ventilating fan includes a sirocco fan disposed in a box-shaped body and an adapter connected to an air outlet of the sirocco fan. The sirocco fan is composed of two opposite scroll plates with scroll shapes and a casing plate sandwiched between the two scroll plates. An overall air inlet of the sirocco fan is disposed on the first scroll plate and a central line of the air outlet of the adapter is offset towards the second scroll plate. The present invention is advantageous in that no turbulence is generated at the adapter and the wind amount of the ventilating fan is thus ensured and noise is reduced. Therefore, the present invention can provide a small air blowing device with high efficiency and improve stability of performance of the product.

Abstract: Various technologies related to achieving financial neutrality in light of transition from one medical classification system to another are described. Mappings between and among codes such as diagnosis codes, procedure codes, and payment codes can be explored and chosen based on comparison of financial impact among candidate codes. To increase performance, weighting in favor of principal codes can be supported. Such weighting can be throttled for adjustment. Other features, including generating replacement codes based on chosen mappings, can be implemented.

Abstract: A carriage printer includes a printhead; a carriage guide disposed along a carriage scan direction, the carriage guide including a first end and a second end opposite the first end; a carriage for transporting the printhead along the carriage scan direction across the print region, the carriage including a bearing surface that is configured to contact the carriage guide as the carriage transports the printhead; a plurality of carriage guide supports each including a support surface, the plurality of carriage guide supports including a first carriage guide support disposed proximate the first end; a second carriage guide support disposed proximate the second end; and a third carriage guide support disposed between the first carriage guide support and the second carriage guide support; a first biasing force applied in a bias direction proximate the first end; and a second biasing force applied in the bias direction proximate the second end.

Abstract: A system level scheme for networking of implantable devices, electronic patch devices/sensors coupled to the body, and wearable sensors/devices with cellular telephone/mobile devices, peripheral devices and remote servers is described.

Abstract: Described herein is the synthesis of alkylated and semi-synthetic glycosaminoglycosan ethers, referred to herein as “SAGEs.” The synthesis of sulfated alkylated SAGEs is also described. The compounds described herein are useful in a number of applications including wound healing, drug delivery, and the treatment of a number of inflammatory diseases and skin disorders.

Abstract: A process is disclosed for making CF3CF2CH3, CF3CF?CH2 and/or CF3CCl?CH2. The process involves reacting at least one starting material selected from the group consisting of halopropanes of the formula CX3CHClCH2X, halopropenes of the formula CClX2CCl?CH2 and halopropenes of the formula CX2?CClCH2X, wherein each X is independently F or Cl, with HF in a reaction zone to produce a product mixture comprising HF, HCl, CF3CF2CH3, CF3CF?CH2 and CF3CCl?CH2; and recovering the CF3CF2CH3, CF3CF?CH2 and/or CF3CCl?CH2 from the product mixture.

Abstract: Disclosed are methods of identifying an agent that modulates an NFAT regulator protein. One such method comprises contacting at least one test agent with a recombinant cell comprising at least one NFAT regulator protein or fragment or derivative thereof, assessing the effect of the test agent on an activity, interaction, expression, or binding to the NFAT regulator protein or fragment or derivative thereof, and identifying the test agent that has an effect on an activity, interaction, expression, or binding to the NFAT regulator protein or fragment or derivative thereof, whereby the identified test agent is characterized as an agent that modulates an NFAT regulator protein.

Abstract: The present disclosure provides isolated monoclonal antibodies that specifically bind to mesothelin with high affinity, particularly human monoclonal antibodies. Preferably, the antibodies bind human mesothelin. In certain embodiments, the antibodies are capable of internalizing into mesothelin-expressing cells or are capable of mediating antigen dependent cellular cytotoxicity. The invention further provides anti-mesothelin antibodies that can inhibit the binding of mesothelin to the ovarian cancer antigen CA125. Nucleic acid molecules encoding the antibodies of this disclosure, expression vectors, host cells and methods for expressing the antibodies of this disclosure are also provided. Antibody-partner molecule conjugates, bispecific molecules and pharmaceutical compositions comprising the antibodies of this disclosure are also provided.

Abstract: Disclosed herein are processes for the production of hydrofluoroolefins by dehydrofluorination. Also disclosed herein are processes for separation of hydrofluoroolefins from hydrofluorocarbons and from hydrogen fluoride.