Abstract: A computing device is described. The computing device includes input/output (I/O) circuitry to receive sensory data and a trusted execution environment to monitor the I/O circuitry to detect one or more context characteristics of the computing device and to authenticate user identity based on context characteristics.

Abstract: A microfluidic device includes a particle sorting region having a first, second and third microfluidic channels, a first array of islands separating the first microfluidic channel from the second microfluidic channel, and a second array of islands separating the first microfluidic channel from the third microfluidic channel, in which the island arrays and the microfluidic channels are arranged so that a first fluid is extracted from the first microfluidic channel into the second microfluidic channel and a second fluid is extracted from the third microfluidic channel into the first microfluidic channel, and so that particles are transferred from the first fluid sample into the second fluid sample within the first microfluidic channel.

Abstract: Systems and methods are provided for sample processing. A device may be provided, capable of receiving the sample, and performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing multiple assays. The device may comprise one or more modules that may be capable of performing one or more of a sample preparation, sample assay, and detection step. The device may be capable of performing the steps using a small volume of sample.

Abstract: The present invention relates to methods for developing engineered T-cells for immunotherapy that are non-alloreactive. The present invention relates to methods for modifying T-cells by inactivating both genes encoding T-cell receptor and an immune checkpoint gene to unleash the potential of the immune response. This method involves the use of specific rare cutting endonucleases, in particular TALE-nucleases (TAL effector endonuclease) and polynucleotides encoding such polypeptides, to precisely target a selection of key genes in T-cells, which are available from donors or from culture of primary cells. The invention opens the way to standard and affordable adoptive immunotherapy strategies for treating cancer and viral infections.

Abstract: The present disclosure is directed toward systems and methods that allow users to efficiently and effectively create and identify segments of usage patterns. For example, systems and methods described herein allow marketers to query and return sequential segments including sequence conditions based on user-defined dimension item values. Furthermore, systems and methods described allow marketers to query and return sequential segments including sequential events based on user-defined dimension variables. In addition to the foregoing, systems and methods described herein allow marketers to query and return sequential segments defined by repeated events performed at given regularity or frequency.

Abstract: A driveshaft assembly includes a tube having a balancing weight attached thereto. A tube yoke is attached to the tube. A damper assembly is attached to the tube yoke. The damper assembly includes a dampening media and an inertia ring. The dampening media is disposed over an outer surface of the tube yoke and the inertia ring is secured to the dampening media.

Abstract: A method for operating a source node includes receiving a data path validation request command requesting validation of a path associated with a traffic flow identified in the data path validation request command, and determining a first hop sequence in accordance with the path being validated, wherein the first hop sequence is identical to a second hop sequence associated with a non-validation request packet associated with the path being validated. The method also includes generating, by the source node, a validation request packet in accordance with the data path validation request command, the validation request packet comprises route information associated with the first hop sequence, an alert flag set to a specified value, and a path validation header specifying processing performed by nodes receiving the validation request packet, and transmitting, by the source node, the validation request packet in accordance with the route information.

Abstract: Disclosed is a system infrastructure that allows for the online and social creation of music and musical thoughts in real-time or near real-time by amateurs and professionals. Individual musical contributions are combined into a single, cohesive musical thought that is presented for approval to the collaborating creators. This solution is extensible from the world of music to other creative endeavors including the written word, video, and digital images. The foregoing system infrastructure powers and supports the online and social creation of music and musical thoughts in real-time or near real-time by amateurs and professionals alike.

Abstract: A side mirror system for a vehicle is provided, including right and left mirror units, each including multiple mirrors, which are configured to be adjustable for viewing vicinities of the vehicle during driving forward and during driving in reverse. One or more of the multiple mirrors are configured to be adjustable for viewing a blind spot. The system further includes a mirror control module coupled to the right and left mirror units and used for adjusting mirror orientations and storing one or more settings of the mirror orientations customized for the one or more users, respectively. The setting for each of the one or more users includes a first subset for driving forward and a second subset for driving in reverse, and the mirror control module controls the mirror orientations according to the second subset for driving in reverse upon detecting that the gear is in reverse.

Abstract: A heat shrink tunnel with width adjustment includes a pair of opposing side wall assemblies, each including an outer wall and an inner perforated wall defining a plenum therebetween. The opposing side walls define a product path with the side wall assemblies being movable toward and away from each other. A heater/blower assembly disposed in each of the opposing side walls and has an outlet directed into the product path. A shroud extends over the side wall assemblies and an open top space between the side all assemblies. The side wall assemblies extend upwardly toward an inside of the shroud so as to define a small gap between tops of the side wall assemblies and the inside of the shroud. The shroud has a bottom wall. A conveyor is configured to convey items through the heat shrink tunnel. A tunnel includes a side wall assembly width adjusting assembly to move the side walls toward and away from one another by actuation of a single actuator.

Abstract: A method for installing a drop terminal includes providing a drop terminal assembly including a drop terminal having an exterior surface, a first cable spool engaged to the exterior surface of the drop terminal, a second cable spool engaged to the first cable spool and a fiber optic cable having a first length disposed about the first cable spool and a second length disposed about the second cable spool. The drop terminal assembly is rotated to deploy the second length of fiber optic cable. The second cable spool is removed. The first length of fiber optic cable is bundled. The bundled first length of fiber optic cable is removed from the first cable spool. The drop terminal is removed from the first cable spool. The drop terminal is mounted to a structure.

Abstract: A microwavable tray containing a preserved, such as frozen, preferably liquid, food product. The tray can be capable of being folded at least in half and closed after microwaving. The liquid food product contained in the tray has the consistency and texture after microwaving of freshly prepared product, allowing it to be folded at least in half when the tray is folded, or even without a folding tray. During the microwave process, various fillings can be added to the product ether frozen or unfrozen prior to folding.

Abstract: This disclosure provided methods of cloning a phage genome. Also provided are methods of making a recombinant phage genome. In some embodiments the phage genome is engineered to comprise a heterologous nucleic acid sequence, for example a sequence comprising an open reading frame. In some embodiments the phage genome is cloned in a yeast artificial chromosome. Recombinant phage genomes and recombinant phage are also provided. In some embodiments the methods are high throughput methods such as methods of making aa plurality of recombinant phage genomes or recombinant phage. Collections of recombinant phage genomes and recombinant phage are also provided.

Abstract: A string box and method of use thereof. The string box may be designed in any shape or size and be made up of any rigid material and the string may be designed in any shape or size and be made of any material such as cotton, cat gut, nylon, plastic, nanoparticle, graphine like material, atoms or any material within the realm of science and knowledge that would provide enough strength to act as a string type of material that can be used to suspend the object with enough strength to hold the item being shipped, stored or otherwise used so that the object being placed in the box is in suspension essentially keeping the object being damaged or hitting the sides of the container it is being shipped, stored or otherwise used in. The box is uniquely designed to allow for a simple one-step process using a box with an integrated string system that is used to suspend an article to be to be packaged.

Abstract: An electrical distribution unit includes a first housing and at least one volume compensation system connected to the first housing. The at least one volume compensation system includes a compensator housing and a member, arranged to be movable inside the compensator housing to compensate for changes in volume caused by changes in pressure and/or temperature inside and/or outside of the apparatus.

Abstract: There is disclosed a network communication system that includes data sources and of switches. Each of the data sources and switches is interconnected by a packet-switched network, and is synchronized to a common clock. The system also includes a network controller that maintains records of network characteristics including a transmission delay for each of the data sources and switches, and a transmission delay for links in the packet-switched network. The network controller processes the network characteristics to generate, for each of a plurality of packets of a given type of traffic: a path from a particular data source, and through at least one particular switch, and a schedule of departure times at each of the particular data source and the at least one particular switch. The path and the schedule are optimized to meet jitter requirements for the given type of traffic.

Abstract: A recoiling energy absorbing system is interpositioned between an outer shell that is exposed to percussive impact and a foundation. An energy absorbing layer with friction lugs is positioned inside the outer shell. The energy absorbing layer includes one or more energy absorbing modules with optional veins and drain holes. At least some of the modules are provided with one or more energy absorbing units that extend from an upper basal layer. At least some of the energy absorbing units are provided with a flexible wall that extends from the upper basal layer. The energy absorbing units at least partially absorb energy generated by an impacting object due to the flexible wall bending inwardly or outwardly and recoiling nondestructively after single or multiple impacts to its undeflected configuration.

Abstract: A fiber optic connector holder is sized to fit within an opening for mounting a fiber optic adapter. The fiber optic connector holder is configured to permit a fiber optic connector with a dust cap positioned about a ferrule and a polished end face of an optical fiber held by the ferrule to be inserted within and releasably held by the connector holder. A system for holding fiber optic connectors includes a fiber optic connector holder mounted within an opening in a bulkhead for mounting a fiber optic adapter. The fiber optic connector holder is configured to receive a fiber optic connector with a dust cap mounted about a ferrule and polished end face of an optical fiber held by the ferrule. An optical fiber connector may be held to a bulkhead when the fiber optic connector includes a dust cap mounted about a ferrule and a polished end face of an optical fiber held by the ferrule.

Abstract: An angle flow valve comprises a carriage. The carriage comprises a first recess, a flow restrictor in the first recess, a second recess, and a relief valve in the second recess. A first port is fluidly connected to the first recess. An angled flow path is fluidly connected to the first recess and to the second recess. A second port is fluidly connected to the angled flow path. The first recess is parallel to the second recess. A solenoid assembly is mounted to the carriage. The solenoid assembly comprises a lead, a bobbin, coil windings, a pole piece, a flux collector, and a sleeve. An integrally formed overmold layer surrounds the carriage and the solenoid assembly.

Abstract: A method of processing a non-magnetic alloy workpiece comprises heating the workpiece to a warm working temperature, open die press forging the workpiece to impart a desired strain in a central region of the workpiece, and radial forging the workpiece to impart a desired strain in a surface region of the workpiece. In a non-limiting embodiment, after the steps of open die press forging and radial forging, the strain imparted in the surface region is substantially equivalent to the strain imparted in the central region. In another non-limiting embodiment, the strain imparted in the central and surface regions are in a range from 0.3 inch/inch to 1 inch/inch, and there exists no more than a 0.5 inch/inch difference in strain of the central region compared with the strain of the surface region of the workpiece. An alloy forging processed according to methods described herein also is disclosed.