Abstract: Systems and methods herein present a multi-modal model, or insight miner, for agricultural use. The model is used for generating actionable insights from time-series agricultural data. To do so, a control system of a farming machine includes the insight miner and a training module. The miner ingests agricultural information (e.g., time series field measurements), identifies trends in the time-series data (e.g., increasing, decreasing, etc.), and determines potential farming actions to take based on identified trends. To do so, the model generates visual representations of the time-series data, inputs the visual representations into a model to obtain a natural language description of that data, and enact farming actions based on the insights obtained. The training module trains the model by generating visual representation and natural language pairs, which are used to train the model.

Abstract: The present invention relates to a C-terminal fragment (such as ApoE CT) of apolipoprotein E (ApoE) and modified ApoE2 and an application of the fragment in inhibiting ?-secretase activity. In one aspect, the present invention provides an isolated ApoE construct, which contains an ApoE polypeptide, the ApoE polypeptide: (1) contains a fragment from an amino acid sequence as shown by SEQ ID NO: 12, a first amino acid residue at a N-terminal of the fragment being an amino acid residue at any position between positions 215-221 of SEQ ID NO: 12, and a last amino acid residue at a C-terminal of the fragment being an amino acid residue at any position between positions 274-299 of SEQ ID NO: 12; or (2) the amino acid sequence has at least about 70% sequence identity with the fragment of (1), and retains at least about 50% of inhibition of the fragment of (1) against ?-secretase enzymatic digestion activity.

Abstract: The present disclosure provides a detector substrate and a flat panel detector, the detector substrate includes a substrate base and detector pixel units on the substrate base, each detector pixel unit includes: a driver circuit; a photoelectric conversion device disposed on a side, away from the substrate base, of the driver circuit, the photoelectric conversion device including at least two photoelectric conversion structures connected in series, a bottom electrode of a first photoelectric conversion structure being electrically connected with the driver circuit, and a top electrode of an nth photoelectric conversion structure being electrically connected with a bottom electrode of an (n+1)th photoelectric conversion structure, with n being greater than or equal to 1; and a bias voltage line on a side of the photoelectric conversion device away from the substrate base, the bias voltage line being electrically connected to a top electrode of a last photoelectric conversion structure.

Abstract: A substrate includes a substrate body and a top copper layer disposed on the substrate body. Multiple insulated channels are disposed on the top copper layer. The top copper layer forms a top circuit structure based on the multiple insulated channels. A light-emitting element installation region is disposed on the top layer circuit structure. The top copper layer in the light-emitting element installation region protrudes upward to form at least one copper layer boss. Multiple light-emitting element welding positions are disposed in the light-emitting element installation region. A light-emitting element welding position is disposed on any copper layer boss. The copper layer boss is configured to adjust the height of the light emission surface of a light-emitting element disposed in the light-emitting element installation region.

Abstract: A display panel and a display device. The display panel includes: a driving substrate, a pixel defining layer, and repeating units. Each repeating unit includes: an electrically conductive isolation structure, including a first electrically conductive isolation structure and a second electrically conductive isolation structure; wherein the first electrically conductive isolation structure forms a first pixel holding region and a second pixel holding region; a side of the second electrically conductive isolation structure toward the first electrically conductive isolation structure is formed with a third pixel holding region.

Abstract: A display substrate, including: a first base substrate, including a display region and a peripheral region surrounding the display region; at least one common voltage line in the display region, each being configured with at least one conductive connection region; a first passivation layer on a side of the common voltage line away from the first base substrate; a common electrode on a side of the first passivation layer away from the first base substrate; a second passivation layer on a side of the common electrode away from the first base substrate; a pixel electrode on a side of the second passivation layer away from the first base substrate; and a first conductive connection electrode in the corresponding conductive connection region and in the same layer as the pixel electrode, where the common electrode is electrically connected to the common voltage line through the first conductive connection electrode.

Abstract: A display panel and a display device are provided. An organic light-emitting layer includes a doped region and an undoped region, and the undoped region is located between the doped region and the hole blocking layer. When the display panel is in a low grayscale display state, an exciton concentration distribution curve of the organic light-emitting layer includes a first peak located in the doped region and a second peak located in the undoped region, and a peak value of the second peak is less than a peak value of the first peak.

Abstract: Multiple voltage threshold integrated circuit structures with local layout effect tuning, and methods of fabricating multiple voltage threshold integrated circuit structures with local layout effect tuning, are described. For example, an integrated circuit structure includes a first fin structure or vertical arrangement of horizontal nanowires. A second fin structure or vertical arrangement of horizontal nanowires is laterally spaced apart from the first fin structure or vertical arrangement of horizontal nanowires. An N-type gate structure is over the first fin structure or vertical arrangement of horizontal nanowires. A P-type gate structure is over the second fin structure or vertical arrangement of horizontal nanowires, the P-type gate structure in contact with the N-type gate structure with a PN boundary between the P-type gate structure and the N-type gate structure.

Abstract: Provided are a display panel and a display device. The display panel includes isolation columns and a partition insulating layer. The partition insulating layer is disposed on at least one of a first side surface of the isolation column facing a hole region or a second side surface of the isolation column facing away from the hole region.

Abstract: An integrated circuit structure comprises a fin extending from a substrate, the fin comprising source and drain regions, and a channel region between the source and drain regions. A multilayer high-k gate stack comprising a plurality of materials extends conformally over the fin over the channel region. A gate electrode is over and on a topmost material in the multilayer high-k gate stack. Fluorine is implanted in the substrate beneath the multilayer high-k gate stack or in the plurality of materials comprising the multilayer high-k gate stack.

Abstract: The present disclosure provides a low dielectric polymer substrate and a preparation method thereof. More specifically, the present disclosure provides a low dielectric polymer substrate to which metal or ceramic may be deposited with high adhesion without a separate adhesive layer through surface modification of a polymer substrate and a preparation method thereof.

Abstract: A device for assessing early dementia by testing gripping strength comprises a main member, a sensing member, and a control system. The main member has a display portion and a gripping portion. The sensing member is connected to the gripping portion to be pressed by a subject to generate a sensing signal. The control system is provided in the main member and having a control unit, a timer, a grip sensing module, and a determining module. The timer records a pressing time of the subject. The grip sensing module receives the sensing signal from the sensing members and generates a gripping strength signal according to the sensing signals. The determining module receives the pressing time and the gripping strength signal, and generates an assessing result by comparing the gripping strength signal with a gripping strength threshold and comparing the pressing time with a time threshold.

Abstract: A manufacturing method for a single-crystal silicon rod and a single-crystal furnace. The single-crystal silicon rod is pulled through a single-crystal furnace, and a crucible of the single-crystal furnace has a depth ranging from 680 mm to 800 mm. The manufacturing method for a single-crystal silicon rod includes: initially charging a silicon material to the crucible, wherein a contact area between the silicon material in the crucible and the crucible is a, a contact area between a liquid level of the silicon material in the crucible and the outside is b, and 1.2?a/b?3.7.

Abstract: A male penis site magnetic resonance imaging integrated coil having an erection assisting function includes a cover body, a negative pressure suction erection assisting apparatus, a programmable erection degree control system, and a multi-channel magnetic resonance imaging coil, and is connected to a full-automatic magnetic resonance contrast agent injection system through a pipeline. The integrated coil is similar to a penis in shape and can be used for penis magnetic resonance imaging to obtain a high-quality image; the negative pressure suction erection assisting apparatus can enable a patient having erectile dysfunction to reach a penile erection state without injection of an erection assisting drug. By adjusting blood flow volume and blood flow speed of a penile blood vessel through the erection degree control system, penis cavernous body angiography can be performed to achieve non-invasive diagnosis of the patient having erectile dysfunction, and cavernosography is expected to be replaced.

Abstract: A display panel and a display device are provided by the present application. The display panel includes a substrate, an inorganic insulating layer, a plurality of pixel-driving circuits, an organic insulating layer, and a light-emitting layer. The organic insulating layer is disposed on a side of the inorganic insulating layer away from the substrate, and the light-emitting layer is disposed on a side of the organic insulating layer away from the substrate. The inorganic insulating layer includes a first inorganic insulating sub-layer, and a refractive index of the first inorganic insulating sub-layer is less than refractive index of the organic insulating layer.

Abstract: An exemplary robotic needle insertion system is disclosed that can provide respiration compensated needle insertion for an accurate and efficient ablation, biopsy, draining placement of a needle, among other surgical procedures. The system employs a robotic instrument comprising (i) a needle insertion mechanism configured to deliver the needle insertion in a step-wise manner that mimics the current clinical practice by inserting the needle (e.g., RFA needle) according to respiration and other motion and (ii) a probe manipulation mechanism to direct an ultrasound probe to provide intraoperative image guidance for the needle insertion.

Abstract: The invention relates to indoline derivatives and uses thereof for treating and/or preventing an inflammatory condition or fibrosis diseases, and tumor or cell proliferative diseases.

Abstract: The present technology relates to copolymers of single ion conducting monomers and/or of neutral monomers, and relates to the methods of making them.

Abstract: An aerosol-generating device is provided, including: a housing including a housing part, in which a venting channel extends from a housing part outer opening to a housing part inner opening, and in which the venting channel extends in at least two different directions inside the housing part along an extension thereof from the housing part outer opening to the housing part inner opening. A method of manufacturing the aerosol-generating device is also provided. An aerosol-generating system including the aerosol-generating device and an aerosol-generating article is also provided.

Abstract: Provided herein are compound-linker constructs and antibody-drug-conjugates of compounds of formula (Y-1), (Y-2), (Y-3), (A), (B), (C), I, II, III, IV or V that are useful as modulators of STING (Stimulator of Interferon Genes). Also provided are synthesis, compositions and uses of such compound-linker constructs and antibody-drug-conjugates.