Abstract: A hydrocarbon-based ionomer for a membrane-electrode assembly includes a block copolymer. The block copolymer includes a triblock copolymer that is represented by A1n1-Bm-A2n2. A1 is a first hydrophobic domain, B is a hydrophilic domain, A2 is a second hydrophobic domain, n1 and n2 each is an integer greater than or equal to 100 and less than or equal to 4,000, and m is an integer greater than or equal to 100 and less than or equal to 8,000.

Abstract: Provided are a fused bicyclic derivative, a pharmaceutically acceptable salt, a crystal form thereof and a preparation method therefor. Specifically, provided are a hydrochloride, a mesylate, an acetate and a tartrate of the compound of formula (I), and a preparation method therefor and a crystal form thereof.

Abstract: Rotational molding processes for producing hollow articles include the steps of: a) filling a mold with a polymer composition comprising: i) an organic polymer; and ii) a rotational molding densification accelerator (RMDA) selected from the group consisting of alkoxylated fatty alcohols, alkoxylated fatty esters, alkoxylated fatty amines, alkoxylated fatty amides, and combinations thereof; b) rotating the mold around at least one axis while heating the mold in an oven, thereby fusing the composition and spreading it to the walls of the mold; c) cooling the mold; and d) opening the mold; and e) removing the hollow article from the mold. The rotational molding processes using such polymer composition results in faster densification, which allows for reduction in overall cycle times for making the hollow articles.

Abstract: The present disclosure discloses a method and system for designing a solution heat-treatment process of a single-crystal superalloy, and relates to the field of numerical simulation-material processing crossover techniques.

Abstract: A portable fan includes an airflow portion and a handheld portion. The airflow portion includes rotation air blades and a drive portion that is driveably connected to the rotation air blades. The drive portion is a three-phase motor that is configured to drive the rotation air blades to rotate to generate an airflow. The handheld portion is connected to the airflow portion. A power supply assembly is arranged inside the handheld portion; and the power supply assembly is electrically connected to and supply power to the three-phase motor.

Abstract: An adjustable hinge for mounting a door on a cabinet frame that comprises a hinge cup and arm link having a first end and a second end. The first end is coupled to the hinge cup and configured to pivot relative to the hinge cup between an open position and closed position. A bottom plate is adjustably coupled to the arm link by a first adjustment screw. A cover plate is adjustably coupled to the bottom plate by a second adjustment screw. A lower surface of the cover plate is disposed substantially parallel to an upper surface of the bottom plate, and a majority of the area of the lower surface of the cover plate directly contacts the upper surface of the bottom plate.

Abstract: Examples are disclosed that relate to fans configured to automatically adjust for imbalances in mass. One example provides a self-balancing fan, comprising a hub comprising a plurality of blade interfaces, and a plurality of blade structures each attached to a corresponding blade interface of the hub, each blade interface comprising a tapered notch in the hub and being configured to increase a balancing force exerted by the hub against the blade structure as a function of increasing distance of the blade structure from the hub.

Abstract: A biohydrogen production device of corn stalks based on synchronous saccharification and fermentation and a hydrogen production method thereof are provided. The biohydrogen production device has a vertical fermenter, an irradiation pretreatment unit, an enzymolysis saccharification unit, a dark fermentation unit, a photofermentation unit, a power supply box and a hydrogen storage tank. The method and device utilize the high specificity of different microorganisms to the substrate to combine the dark fermentation and the process of photofermentation hydrogen production. The method and device can be used for the preparation of hydrogen.

Abstract: An embodiment of an electrochemical system includes a reaction fluid supply line configured to supply a reaction fluid, a first gas-liquid separator connected to the reaction fluid supply line and configured to separate the reaction fluid into a gaseous reaction fluid and a liquid reaction fluid, a circulation line connected to the first gas-liquid separator and configured to allow the liquid reaction fluid to circulate therethrough, a water electrolysis stack provided in the circulation line, and a first bypass line having a first end at an upstream side of the water electrolysis stack and connected to the circulation line, and a second end at a downstream side of the water electrolysis stack and connected to the circulation line.

Abstract: Methods which make use of baculovirus vector (BV)-magnetic nanoparticle (BV-MNP) complexes to facilitate in vivo delivery of clustered regularly interspaced palindromic repeat (CRISPR) systems are provided. BV-MNP complexes carrying a CRISPR nuclease and a guide RNA having homology to an immune checkpoint gene can be administered to a subject to inhibit the immune checkpoint gene. Inhibition of the immune checkpoint gene can promote a desired immune response in the subject. Methods which leverage the contrast provided by MNPs in BV-MNP complexes in combination with magnetic resonance imaging (MRI) to detect in vivo delivery of CRISPR systems are also provided.

Abstract: Methods and compositions are provided for producing a smooth muscle cell (SMC) from a pluripotent stem cell, e.g., an induced pluripotent stem cell (iPSC), via MEOX1 overexpression. MEOX1 expression can be induced using any convenient method, e.g., by introducing an exogenous nucleic acid encoding MEOX1 or by using a tool such as CRISPRa to stimulate expression from the MEOX1 endogenous locus.

Abstract: Provided are a T-shaped reamed pile, a composite foundation, and a construction method for the composite foundation, relating to the technical field of civil engineering. The composite foundation is composed of a T-shaped reamed pile, soil between piles, and a cushion layer. The T-shaped reamed pile is composed of a core pile, a reamed body surrounding the outside of the core pile. A depth of the core pile is not lower than that of the reamed body, the reamed body includes an upper reamed body, and a lower reamed body, and a diameter of the upper reamed body is larger than that of the lower reamed body. The core pile is a precast pile, the reamed body is a cast-in-place reamed body, and the cushion layer is a sand-gravel cushion layer, or a reinforced cement-soil cushion layer.

Abstract: Provided is an adenovirus-associated virus (AAV) product containing fewer non-functional capsids, such as deamidated empty AAV capsids, deamidated AAV capsids comprising a portion of the transgene, and deamidated full capsids, than AAV products currently in use. The AAV product contains a higher ratio of functional capsids to non-functional capsids (deamidated, hydrophobic capsids), compared to a control AAV product purified solely by ultracentrifugation, by anion-exchange chromatography (AEX) without a fatty acid mobile phase. Methods of making and using the AAV product are also provided, including separating functional capsids from non-functional capsids with anion-exchange chromatography (with fatty acid mobile phase), HIC, or chromatography with a mixed mode resin. Such methods also include maintaining transfected cells in a bioreactor about two days post-transfection, optionally at about 30-38° C., and subsequently separating the functional capsids from the non-functional capsids.

Abstract: Techniques for controlling a trajectory of a mud motor directional drill are disclosed. A system receives one or more inputs pertaining to constraints for a wellbore in a mud motor drilling operation. The system constructs, as a function of the one or more inputs, a discretized well depth horizon. One or more binary slide and rotate commands for controlling a directional drill within the wellbore is generated based on an analysis of the discretized well depth horizon. The system controls the directional drill according to the one or more binary slide and rotate commands.

Abstract: The disclosure generally relates to systems, methods, and apparatuses for magnetic bead loading. An example embodiment of the disclosure relates to an apparatus including a vertically oriented plate having a first major surface and a second major surface opposite the first major surface; a magnet holder securing a magnet in proximity to the first major surface of the vertically oriented plate; a drive mechanism coupled to the magnet holder and operable to move the magnet holder and magnet in parallel to the first major surface of the vertically oriented plate; and a substrate holder to receive a substrate and hold the substrate in a vertical orientation against the surface of the vertically oriented plate.

Abstract: A self-stabilizing integrally-molded pillar filling structure for underground mines is provided, belonging to the field of supporting structures, which includes an airbag, and the airbag is provided with a feed filling port and a gas inflation port; a telescopic bearing piece, and the telescopic bearing piece is fixedly provided on an inner surface of the airbag and is capable of expanding and contracting with volume change of an inner cavity of the airbag; and steel hoops, and the steel hoops are fixedly provided on an outer surface of the airbag.

Abstract: Disclosed herein are a Cas12i polypeptide and use thereof in a CRISPR-Cas system. Specifically disclosed herein are a Cas12i polypeptide, a Cas12i fusion polypeptide, a guide RNA, a complex formed by the Cas12i polypeptide or fusion polypeptide with the guide RNA, a nucleic acid, a vector, a vector system, a delivery system, a kit, a composition, and a method for modifying a nucleic acid using the components described above.

Abstract: Provided are a circulating water control method and system, a computer-readable storage medium, and an air conditioner. A first water delivery assembly of a water delivery device of the air conditioner is in communication with an indoor drain pan and a spray device, and a second water delivery assembly is in communication with an outdoor drain pan and a space where an indoor heat exchanger is located. The method includes: determining an operating mode of the air conditioner and obtaining water level information of the indoor drain pan and water level information of the outdoor drain pan; and controlling the first and second water delivery assemblies based on the operating mode, the water level information of the indoor drain pan, and the water level information of the outdoor drain pan, to circulate condensate water generated by the air conditioner between an indoor unit and an outdoor unit.

Abstract: A method for synthesizing diacylglycerol, comprising the following steps: (1) mixing an oil, a lipase and a solvent, and carrying out a hydrolysis reaction to obtain a hydrolyzate; and (2) under the action of a diacylglycerol lipase, performing an esterification reaction on the hydrolyzate obtained in step (1) with glycerol; the lipase in step (1) is lipase MAS1 or MAS1-H108A.

Abstract: A head mounted display including a first display, a second display, a transmission component, an electrically controlled driver and a manual adjustment component is provided. The transmission component is connected to the first display and the second display. The electrically controlled driver is coupled to the transmission component. The electrically controlled driver drives the transmission component in an electrically controlled mode to adjust a distance between the first display and the second display. The manual adjustment component is detachably coupled to the transmission component. The manual adjustment component is coupled to and drives the transmission component to adjust the distance between the first display and the second display in a manual mode, and the manual adjustment component is separated from the transmission component in the electronic control mode.