Patents by Inventor Aaron Hennings

Aaron Hennings has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10653791
    Abstract: Provided herein are heavy chain constant regions (referred to as “modified heavy chain constant regions”), or functionally equivalent fragments thereof, that enhance biological properties of antibodies relative to the same antibodies in unmodified form. An exemplary modified heavy chain constant region includes an IgG2 hinge and three constant domains (i.e., CH1, CH2, and CH3 domains), wherein one or more of the constant region domains are of a non-IgG2 isotype (e.g., IgG1, IgG3 or IgG4). The heavy chain constant region may comprise wildtype human IgG domain sequences, or variants of these sequences. Also provided herein are methods for enhancing certain biological properties of antibodies that comprise a non-IgG2 hinge, such as internalization, agonism and antagonism, wherein the method comprises replacing the non-IgG2 hinge of the antibody with an IgG2 hinge.
    Type: Grant
    Filed: November 19, 2015
    Date of Patent: May 19, 2020
    Assignee: BRISTOL-MYERS SQUIBB COMPANY
    Inventors: Nils Lonberg, Alan J. Korman, Mark J. Selby, Bryan C. Barnhart, Aaron P. Yamniuk, Mohan Srinivasan, Karla A. Henning, Michelle Minhua Han, Ming Lei, Liang Schweizer, Sandra V. Hatcher, Arvind Rajpal
  • Publication number: 20190284293
    Abstract: Provided are methods for clinical treatment of tumors (e.g., advanced solid tumors) using an anti-CD73 antibody in combination with an immuno-oncology agent, such as an anti-PD-1 antibody.
    Type: Application
    Filed: March 3, 2017
    Publication date: September 19, 2019
    Inventors: Nils LONBERG, Alan J. KORMAN, Bryan C. BARNHART, Aaron P. YAMNIUK, Mohan SRINIVASAN, Karla A. HENNING, Ming LEI, Emanuela SEGA, Angela GOODENOUGH, Maria JURE-KUNKEL, Guodong CHEN, John S. SACK, Richard Y. HUANG, Martin J. CORBETT, Joseph E. MYERS, Jr., Liang SCHWEIZER, Sandra V. HATCHER, Rachel A. ALTURA, Haichun HUANG, Pingping ZHANG, Edward J. HILT, Michael Nathan HEDRICK
  • Patent number: 9051404
    Abstract: Disclosed herein is an in-reactor produced multi-component copolymer comprises a semi-crystalline component having a crystallinity of 20% or more, and an amorphous component having a crystallinity of 5% or less. The copolymer comprises at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C12 alpha-olefin. The copolymer has a viscosity at 190° C. of at least 530 mPa sec and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer exhibits a good balance of adhesive properties and mechanical strength.
    Type: Grant
    Filed: November 21, 2013
    Date of Patent: June 9, 2015
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Peijun Jiang, Patrick Brant, David Aaron Henning, David Raymond Johnsrud, Charles Lewis Sims
  • Publication number: 20140331387
    Abstract: High performance sport socks including multiple fabrics, and methods of making and using the same, are provided. Under one aspect, a sock includes a first fabric defining a stem and a bifurcated region. The stem can be configured and arranged to be disposed on the Achilles tendon of a wearer, and the bifurcated region can be configured and arranged to be disposed on the calf of the wearer. The sock also can include a second fabric coupled to the first fabric inside of the bifurcated region and configured and arranged to be disposed on the calf of the wearer. The sock also can include a third fabric coupled to the first fabric outside of the bifurcated region and configured and arranged to be disposed on the shin of the wearer.
    Type: Application
    Filed: May 9, 2014
    Publication date: November 13, 2014
    Applicant: Stance, Inc.
    Inventor: Aaron HENNINGS
  • Publication number: 20140080974
    Abstract: Disclosed herein is an in-reactor produced multi-component copolymer comprises a semi-crystalline component having a crystallinity of 20% or more, and an amorphous component having a crystallinity of 5% or less. The copolymer comprises at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C12 alpha-olefin. The copolymer has a viscosity at 190° C. of at least 530 mPa sec and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer exhibits a good balance of adhesive properties and mechanical strength.
    Type: Application
    Filed: November 21, 2013
    Publication date: March 20, 2014
    Inventors: Peijun Jiang, Patrick Brant, David Aaron Henning, David Raymond Johnsrud, Charles Lewis Sims
  • Patent number: 8618219
    Abstract: Disclosed herein is an in-reactor produced multi-component copolymer comprises a semi-crystalline component having a crystallinity of 20% or more, and an amorphous component having a crystallinity of 5% or less. The copolymer comprises at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C12 alpha-olefin. The copolymer has a viscosity at 190° C. of at least 530 mPa sec and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer exhibits a good balance of adhesive properties and mechanical strength.
    Type: Grant
    Filed: September 29, 2006
    Date of Patent: December 31, 2013
    Assignee: ExxonMobil Chemical Patents Inc.
    Inventors: Peijun Jiang, Patrick Brant, David Aaron Henning, David R. Johnsrud, Charles L. Sims
  • Publication number: 20100029851
    Abstract: Disclosed herein is an in-reactor produced multi-component copolymer comprises a semi-crystalline component having a crystallinity of 20% or more, and an amorphous component having a crystallinity of 5% or less. The copolymer comprises at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C12 alpha-olefin. The copolymer has a viscosity at 190° C. of at least 530 mPa sec and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer exhibits a good balance of adhesive properties and mechanical strength.
    Type: Application
    Filed: September 29, 2006
    Publication date: February 4, 2010
    Inventors: Peijun Jiang, Patrick Brant, David Aaron Henning, David R. Johnsrud, Charles L. Sims
  • Publication number: 20080081878
    Abstract: Disclosed herein is an in-reactor produced multi-component copolymer comprises a semi-crystalline component having a crystallinity of 20% or more, and an amorphous component having a crystallinity of 5% or less. The copolymer comprises at least 80 wt % of units derived from propylene and from about 1 to about 20 wt % of units derived from at least one C6 to C12 alpha-olefin. The copolymer has a viscosity at 190° C. of at least 530 mPa sec and a heat of fusion between about 10 and about 70 J/g. An adhesive containing the copolymer exhibits a good balance of adhesive properties and mechanical strength.
    Type: Application
    Filed: September 29, 2006
    Publication date: April 3, 2008
    Inventors: Peijun Jiang, Patrick Brant, David Aaron Henning, David R. Johnsrud, Charles L. Sims
  • Patent number: 5784870
    Abstract: A mower deck lift mechanism which includes a friction disk selectively pivotable into engagement with first and second pulleys of a double pulley jacksheave. A linkage coupled between the friction disk and the deck raises the mower deck when the friction disk engages and rotates with the first pulley, and lowers the deck when the friction disk engages and rotates with the second pulley. Neutral return mechanisms are provided for returning the friction disk to a neutral position when the operator releases a control and when the deck approaches its extreme raised or lowered positions. A cutting height preset mechanism is also provided.
    Type: Grant
    Filed: March 22, 1996
    Date of Patent: July 28, 1998
    Assignee: Deere & Company
    Inventors: Brian David Seegert, Royal Aaron Henning, Daniel Angelo Sebben, Timothy Paul Zellmer, William Garrald Cameron, Wayne Robert Hutchison
  • Patent number: D586080
    Type: Grant
    Filed: July 12, 2007
    Date of Patent: February 10, 2009
    Assignee: GSM (Operations) Pty Ltd
    Inventor: Aaron Hennings
  • Patent number: D603138
    Type: Grant
    Filed: July 16, 2008
    Date of Patent: November 3, 2009
    Assignee: GSM (Operations) Pty Ltd
    Inventors: Aaron Hennings, Beau Campi