Abstract: A unitary composite structure and methods of forming are presented. A method of laying up a unitary composite structure comprises laying up a plurality of dome plies on a rounded end of a mandrel using a plurality of rosettes; laying up a plurality of cylindrical plies on a cylindrical surface of the mandrel using a layup rosette independent of the plurality of rosettes; and forming a transition region comprising a joint between the plurality of dome plies and the plurality of cylindrical plies by varying lengths of the plurality of dome plies and lengths of the plurality of cylindrical plies.

Abstract: A composite pressure hull and methods of forming the composite pressure hull are presented. A unitary first half of the composite pressure hull is laid up. A unitary second half of the composite pressure hull is laid up. The unitary first half is joined to the unitary second half to form the composite pressure hull.

Abstract: A method of delivering digital content for use on an electronic cutting machine. The method includes displaying at least one themed project in a rich internet application, where the themed project has at least one glyph of a glyph collection. The method further includes providing access to the rich internet application over a network and offering purchased access to the glyph collection. Any glyphs of the glyph collection can be added to the themed project. The themed project is cuttable on an electronic cutting machine in communication with the rich internet application.

Abstract: A method forms a multi-ply laminate. A first cutting system cuts and moves a first group of courses into staging positions. Placement robots pick up and place the first group of courses from the staging positions to a layup surface to form a first ply of the multi-ply laminate, changing an orientation of fibers from an initial orientation to a desired orientation for the first ply. A second cutting system cuts and moves a second group of courses into the staging positions while the placement robots are picking up and placing the first group of courses. The placement robots pick up and place the second group of courses from the staging positions to the layup surface to form a second ply of the multi-ply laminate after the first ply has been formed, changing the orientation of the fibers from the initial orientation to the desired orientation for the second ply.

Abstract: The present disclosure relates to a device that includes a first metal oxide layer having a first thickness, a second metal oxide layer having a second thickness, and a base layer having a third thickness, where the first metal oxide layer is positioned between the base layer and the second metal oxide layer, at least one of the base layer and/or the first metal oxide layer includes a carbon-containing material, and at least one of a carbon concentration gradient and/or an oxygen concentration gradient is present across at least one of a portion of the first thickness and/or a portion of the third thickness. In some embodiments of the present disclosure, the first metal oxide layer may be permeable to an oxygen-containing compound. In some embodiments of the present disclosure, the oxygen-containing compound may include at least one of O3, N2O, and/or H2O2.

Abstract: Disclosed are various embodiments for massively parallel compilation of application code. A compiler application is executed in a compute instance of an elastic computing device. When an instruction to compile source code of an application is received, the compiler application generates virtual processes to compile a portion of the source code of the application separate from the compute instance having the compiler installation executing thereon. When the virtual processes complete the compilation of the source code, build artifacts are linked to generate an executable computing application.

Abstract: Embodiments of the instant disclosure relate to novel compositions and methods for treating cancer in a subject. In certain embodiments, long noncoding RNAs (lncRNAs) are modified to reduce or eliminate methylation at target nucleotides within the lncRNAs to modulate activities such as tumor promoting activities. In some embodiments, the lncRNAs includes HOTAIR (HOX (homeobox) transcript antisense intergenic RNA) or fragment thereof, where one or more nucleotides are substituted to reduce or eliminate methylation at the one or more nucleotide positions. In certain embodiments, the HOTAIR methylation site includes, but is not limited to, a modification at adenine 783 (A783) of SEQ ID. NO:1 or fragment thereof or equivalent position thereof. In other embodiments, modified lncRNAs disclosed herein can be used to treat a health condition where naturally-occurring lncRNAs have adverse effects. In some embodiments, a composition including modified HOTAIR can be used to treat a subject with cancer.

Abstract: Among other things, the present disclosure relates to a wind turbine rotor blade that can be assembled at the site of its wind turbine. The blade includes an internal structure which may be pre-fabricated with connections to the shell skin prior to being transported to the site of its wind turbine. A filler material may be injected into the layers of fabric making up the shell skin at the wind turbine site and allowed to harden at approximately atmospheric conditions.

Abstract: A pyrotechnic switch comprising a pyrotechnic actuator that is electrically coupled to a conductive member and a fuse element element that is electrically coupled or capable of being electrically coupled to the pyrotechnic actuator. The pyrotechnic actuator has an initial state in which a conductive path couples the actuator to the conductive member and an actuated state in which a gap is formed in the conductive member. The pyrotechnic switch comprises a fiber-reinforced polymer composition comprising a polymer matrix that contains a high performance thermoplastic polymer and a plurality of long reinforcing fibers.

Abstract: A vehicle console system includes a body having first and second sidewalls. Each of the first and second sidewalls defines a rail along an inner surface thereof. A support bar slidably engages the rails. The support bar defines a track. A cover assembly is operably coupled to the support bar. The cover assembly includes a base panel coupled to the support bar via a connector assembly and a deployable panel rotatably coupled to the base panel. The cover assembly is configured to translate along a first movement path with the support bar along the rails and a second movement path along the track of the support bar. The cover assembly is configured to rotate along a third movement path between a first side position and a second side position.

Abstract: The present disclosure generally relates to auditory nerve stimulation to create the perception of sound in the brain of a subject such as an animal or human being. In one form, a system includes an implantable electrode array including a plurality of spaced apart micro-needles. The system also includes a first electrical lead electrically coupled to and extending from the implantable electrode array, and an auditory signal device configured to produce one or more electrical signals representative of communications received from an external processor. An interposer is configured to electrically couple the implantable electrode array and the auditory signal device in an arrangement where one or more electrical signals produced by the auditory signal device may be transmitted through the first electrical lead to the implantable electrode array. Various novel stimulation strategies can be employed, such as place modulated stimulation signals.

Abstract: Among other things, the present disclosure relates to a wind turbine rotor blade that can be assembled at the site of its wind turbine. The blade includes an internal structure which may be pre-fabricated with connections to the shell skin prior to being transported to the site of its wind turbine. A filler material may be injected into the layers of fabric making up the shell skin at the wind turbine site and allowed to harden at approximately atmospheric conditions.

Abstract: A bipedal walking robot uses a quasi-passive control scheme and a simplified mechanical design. The walking robot has a pair of legs connected to a body through a passive hip joint, which is offset from a center of gravity of the walking robot. A nonconcentric, curved foot is attached at to each leg by a prismatic joint. Extension and retraction of the prismatic joint initiates the walking sequence of the robot, with each foot retracted during the swing phase and extended during the stance phase. Directional changes are controlled by changing a phase offset in the actuation of each foot.

Abstract: A leaf spring vehicle suspension system includes a chassis rail and an axle. The suspension system also includes a first stage leaf spring. The suspension system further includes a second stage leaf spring. The suspension system yet further includes a third stage leaf spring operatively coupled at a first end and a second end to the chassis rail, wherein the first stage leaf spring is located below the third stage leaf spring and the second stage leaf spring is located below the first stage leaf spring. The suspension system also include a spacer in abutment with a leaf spring, wherein the spacer is formed of at least one composite material.

Abstract: A light assembly includes a light source and a lens. The lens includes a hardcoat surface that protects the lens. The light source is positioned close to the lens, and a microtexture is defined in the hardcoat material to increase diffusion of the light to overcome the limitations of the close spacing between the lens and the light source. The hardcoat material and microtexture may be applied to both sides of the lens or one side of the lens. The light source may be a plurality of spaced apart LEDs. The microtexture may be applied to the entire surface of the lens or select regions of the lens. The microtexture is defined after the hardcoat is applied, and is defined via removal or disruption of hardcoat material. The microtexture may be defined in different ways to vary the appearance of the microtexture.

Abstract: The present invention provides a polymerizable sanitizing formulation for forming a polymerized anti-microbial agent retaining material on a contact surface. The polymerizable sanitizing formulation comprising: a) a polymerizable water-soluble material; b) at least one initiator for radical polymerization of the polymerizable material to form a polymerized anti-microbial agent retaining material; c) at least one anti-microbial agent for retention within the polymerized anti-microbial agent retaining material; and d) at least one solvent.

Abstract: A gripper includes at least one movable finger. Each movable finger includes a first motor, a second motor, a first motor link having a first end coupled to a rotor of the first motor, a second motor link having a first end coupled to a rotor of the second motor, a finger link having a first end in pivotal connection with a second end of the second motor link and a gripper pad, and a connecting link having a first end in pivotal connection with a second end of the first motor link and a second end in pivotal connection with the finger link. The gripper further includes at least one controller programmed or configured to actuate the first motor and the second motor of each of the at least one movable finger.

Abstract: Joining systems, clamping fixtures, and related systems and methods are generally described.

Abstract: Among other things, the present disclosure relates to a wind turbine rotor blade that can be assembled at the site of its wind turbine. The blade includes an internal structure which may be pre-fabricated with connections to the shell skin prior to being transported to the site of its wind turbine. A filler material may be injected into the layers of fabric making up the shell skin at the wind turbine site and allowed to harden at approximately atmospheric conditions.

Abstract: The invention relates to a highly flowable crosslinkable medical or dental composition comprising a crosslinkable compound, a polymerization initiator and a heterogeneous radiopacifier. Also described is a crosslinked polymer composition obtainable by crosslinking said highly flowable, crosslinkable medical or dental composition and the use of said highly flowable crosslinkable medical or dental composition to fill cavities or hollow structures in human or animal subjects.