Patents by Inventor Abhishek Datta

Abhishek Datta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200181251
    Abstract: Disclosed herein are LRRC33 inhibiting agents and related methods and uses thereof. More specifically, therapeutic agents for inhibiting LRRC33 effects in vivo are provided. Such agents are useful for the treatment of various disorders involving cells expressing LRRC33 or LRRC33-containing complexes on the surface of cells.
    Type: Application
    Filed: May 9, 2018
    Publication date: June 11, 2020
    Inventors: Alan Buckler, Gregory J. Carven, Stefan Wawersik, Thomas Schurpf, Constance Martin, Abhishek Datta, Mark Allen Farmer
  • Publication number: 20200079840
    Abstract: Disclosed herein are monoclonal antibodies and antigen-binding fragments thereof capable of selectively inhibiting TGF?1 with high potency. Related compositions, methods and therapeutic use are also disclosed.
    Type: Application
    Filed: July 11, 2019
    Publication date: March 12, 2020
    Inventors: Abhishek Datta, Allan Capili, Thomas Schurpf, Constance Martin, Kevin B. Dagbay, Christopher Chapron, Stefan Wawersik, Christopher Littlefield, Gregory J. Carven, Alan Buckler, Susan Lin, Justin W. Jackson
  • Publication number: 20190209682
    Abstract: Disclosed herein are therapeutic use of isoform-specific, context-permissive inhibitors of TGF?1 in the treatment of disease that involve TGF?1 dysregulation.
    Type: Application
    Filed: March 22, 2019
    Publication date: July 11, 2019
    Inventors: Thomas Schurpf, Abhishek Datta, Gregory J. Carven, Constance Martin, Ashish Kalra, Kimberly Long, Alan Buckler
  • Publication number: 20190163736
    Abstract: A device may receive information associated with an entity. The information may include a first resource and a second resource. The first resource may be associated with a first file type, and the second resource may be associated with a second file type that is different than the first file type. The first resource may be associated with a first source, and the second resource may be associated with a second source that is different than the first source. The device may extract a plurality of attributes associated with the entity based on the information. The device may implement a natural language processing technique to extract the plurality of attributes. The device may associate the plurality of attributes with a plurality of elements based on extracting the plurality of attributes. The device may provide information that identifies the plurality of elements and the plurality of attributes to permit and/or cause an action to be performed.
    Type: Application
    Filed: August 19, 2016
    Publication date: May 30, 2019
    Inventors: Abhishek Datta SHARMA, Madhura SHIVARAM, Suraj Govind JADHAV, Kaushal MODY, Deepak KUMAR, Guruprasad DASAPPA, Arvind MAHESWARAN
  • Publication number: 20190071493
    Abstract: Disclosed herein are immunoglobulins, such as antibodies, and antigen binding portions thereof, that specifically bind complexes of GARP-TGF?1, LTBP1-TGF?1, LTBP3-TGF?1, and/or LRRC33-TGF?1. The application also provides methods of use of these immunoglobulins for, for example, inhibiting TGF?1 activity, and treating subjects suffering from TGF?1-related disorders, such as cancer and fibrosis.
    Type: Application
    Filed: March 10, 2017
    Publication date: March 7, 2019
    Inventors: Thomas Schurpf, Gregory J. Carven, Abhishek Datta, Kimberly Long
  • Publication number: 20180349776
    Abstract: A system for reconciliation comprises a determination engine to determine whether data is structured or unstructured, a data structuring engine to structure the data, and a rule extraction engine to determine relations between pairs of values of a first set and a second set of data. The system further comprises a matching engine to generate a confidence score for each pair of the values, a categorization engine to classify the pairs of values into matched pairs and unmatched pairs, a validation engine to validate matching and classification of the pairs based on a user feedback, and a learning engine to store details pertaining to the validation of the matching and the classification over a period of time. The learning engine forwards the details to the rule extraction engine and the categorization engine to determine the relations between subsequent pairs of values and classify the pairs based on the stored details.
    Type: Application
    Filed: June 1, 2017
    Publication date: December 6, 2018
    Applicant: ACCENTURE GLOBAL SOLUTIONS LIMITED
    Inventors: Srikrishna RAAMADHURAI, Abhishek Datta Sharma, Siddhartha Asthana, Suresh Venkatasubramaniyan, Himani Shukla, Madhura Shivaram, Chung-Sheng Li
  • Patent number: 10143832
    Abstract: An apparatus for delivering therapeutic electrostimulation across a tissue surface includes a current source, a low current component adapted to contact the tissue surface, a first electrode assembly electrically connected to the current source and supported by the low current component, a second electrode assembly electrically connected to the current source and supported by the low current component and a conductive fluid supported by the low current component for facilitating a flow of electric current across the tissue surface. At least one of the first and second electrodes assemblies includes at least one of a magnetic electrode, a high current component and a non-current component.
    Type: Grant
    Filed: November 9, 2015
    Date of Patent: December 4, 2018
    Assignee: RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK
    Inventors: Marom Bikson, Abhishek Datta, Niranjan Khadka
  • Publication number: 20180207267
    Abstract: Disclosed herein are therapeutic use of isoform-specific, context-permissive inhibitors of TGF?1 in the treatment of disease that involve TGF?1 dysregulation.
    Type: Application
    Filed: January 5, 2018
    Publication date: July 26, 2018
    Inventors: Thomas Schurpf, Abhishek Datta, Gregory J. Carven, Constance Martin, Ashish Kalra, Kimberly Long, Alan Buckler
  • Patent number: 9440063
    Abstract: An electrode assembly for neuro-cranial stimulation includes an electrode, a conductive gel, and an adapter including an interior compartment for positioning the electrode relative to the adapter and for receiving and retaining the conductive gel. The conductive gel contacts the electrode along an electrode-gel interface. An orifice at one end of the interior compartment and adjacent to a positioning surface of the adapter for positioning the electrode assembly against a skin surface of a user enables the conductive gel is able to contact the skin surface of the user to define a gel-skin interface, such that a minimum distance between the electrode-gel interface and the gel-skin interface is maintained between 0.25 cm and 1.3 cm. An electrode assembly mounting apparatus is provided for adjustably positioning a plurality of electrode assemblies against target positions on the cranium.
    Type: Grant
    Filed: December 30, 2009
    Date of Patent: September 13, 2016
    Assignee: RESEARCH FOUNDATION OD THE CITY UNIVERSITY OF NEW YORK
    Inventors: Johnson Ho, Preet Minhas, Marom Bikson, Abhishek Datta, Varun Bansal, Jinal Patel, Dan Steingart, Jorge Vega, Lucas Parra
  • Patent number: 9339642
    Abstract: In some embodiments of the present disclosure, systems and methods for effecting a physiological effect are provided. In some embodiments, a system is provided which comprises a plurality of current sources, where each current source having a positive output and a negative output and each being configured to provide a first current. The system may also include a plurality of stimulating electrodes electrically connected with the plurality of current sources such that at least a pair of the stimulating electrodes share at least one output of at least one of the plurality of current sources. The stimulating electrodes may be configured to provide electrical energy to tissue of a patient at the first current. The system may further include at least one sentinel electrode, and a first voltage monitor configured to monitor a first voltage across the at least one sentinel electrode and at least one of the plurality of stimulating electrodes.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: May 17, 2016
    Assignee: Soterix Medical, Inc.
    Inventors: Marom Bikson, Lucas Cristobal Parra, Abhishek Datta, Niranjan Khadka, Shiraz Azar Macuff
  • Publication number: 20160129237
    Abstract: An apparatus for delivering therapeutic electrostimulation across a tissue surface includes a current source, a low current component adapted to contact the tissue surface, a first electrode assembly electrically connected to the current source and supported by the low current component, a second electrode assembly electrically connected to the current source and supported by the low current component and a conductive fluid supported by the low current component for facilitating a flow of electric current across the tissue surface. At least one of the first and second electrodes assemblies includes at least one of a magnetic electrode, a high current component and a non-current component.
    Type: Application
    Filed: November 9, 2015
    Publication date: May 12, 2016
    Inventors: Marom Bikson, Abhishek Datta, Niranjan Khadka
  • Patent number: 8965514
    Abstract: A method includes coupling electrodes to a patient's head and identifying whether any of the electrodes form a functional set, such that a desired therapeutic effect is achieved when the two or more electrodes deliver a total amount of current to the patient regardless of what portion of the total amount of current each respective electrode carries. One or more constant current sources are provided, each having a supply and return terminal, which supply and return equal amounts of current at any given time. The constant current source(s) are coupled to the electrodes in such a manner that each supply terminal and each return terminal is coupled to no more than the electrodes of a single one of the functional sets, if any, or to a single one of the electrodes not included in one of the functional sets.
    Type: Grant
    Filed: April 13, 2010
    Date of Patent: February 24, 2015
    Assignee: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Varun Bansal, Lucas C. Parra, Xiang Zhou
  • Patent number: 8718778
    Abstract: There is provided method and apparatus for enhancing focality of neurocranial electrostimulation, including: providing a first plurality of electrodes having at least one electrode; providing a second plurality of electrodes having at least two electrodes; locating the first and the second plurality of electrodes on cranium of a subject and supplying electric current of opposite polarities to the first and the second plurality of electrodes. At least one electrode of the first plurality of electrodes is surrounded by at least two electrodes of the second plurality of electrodes. The enhanced focal stimulation may be used to treat ailments or augment cognitive performance. There are also provided methods for treating brain related ailments and performance augmentation.
    Type: Grant
    Filed: September 18, 2008
    Date of Patent: May 6, 2014
    Assignee: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Fortunato Battaglia, Maged Elwassif
  • Patent number: 8494627
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for developing transcranial electrical stimulation protocols are disclosed. In one aspect, a method includes forming a first array of electrodes and optimizing a plurality of electrode parameters within the first array of electrodes to achieve a desired physiological response; identifying one or more electrodes within the optimized first array that have relatively low current compared to the remaining electrodes in the first array; removing the identified low current electrodes from the first array to form a second array of electrodes, wherein the number of electrodes in the second array is less than the number of electrodes in the first array and optimizing a plurality of electrode parameters with the second array of electrodes to achieve a desired physiological response.
    Type: Grant
    Filed: November 11, 2011
    Date of Patent: July 23, 2013
    Assignee: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Lucas C. Parra, Jacek Dmochowski, Yuzhuo Su
  • Publication number: 20120265261
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for developing transcranial electrical stimulation protocols are disclosed. In one aspect, a method includes forming a first array of electrodes and optimizing a plurality of electrode parameters within the first array of electrodes to achieve a desired physiological response; identifying one or more electrodes within the optimized first array that have relatively low current compared to the remaining electrodes in the first array; removing the identified low current electrodes from the first array to form a second array of electrodes, wherein the number of electrodes in the second array is less than the number of electrodes in the first array and optimizing a plurality of electrode parameters with the second array of electrodes to achieve a desired physiological response.
    Type: Application
    Filed: November 11, 2011
    Publication date: October 18, 2012
    Inventors: Marom Bikson, Abhishek Datta, Lucas C. Parra, Jacek Dmochowski, Yuzhuo Su
  • Publication number: 20120245653
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for developing transcranial electrical stimulation protocols are disclosed. In one aspect, a method includes the actions of accepting an image model of target tissue, obtaining a forward model having a first electrode configuration and first electrical stimulation parameters based on electrical stimulation of the target tissue, accepting electrode configuration changes or electrical stimulation parameter changes resulting in a second electrode configuration or second electrical stimulation parameters, determining an optimized tissue model using a least square methodology and based on the second electrode configuration or second electrical stimulation parameter changes, comparing the optimized tissue model with a desired outcome, and providing a confirmation of the optimized model with the desired outcome.
    Type: Application
    Filed: April 13, 2010
    Publication date: September 27, 2012
    Applicant: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Lucas C. Parra, Jacek Dmochowski, Yuzhuo Su
  • Publication number: 20120209346
    Abstract: A method includes coupling electrodes to a patient's head and identifying whether any of the electrodes form a functional set, such that a desired therapeutic effect is achieved when the two or more electrodes deliver a total amount of current to the patient regardless of what portion of the total amount of current each respective electrode carries. One or more constant current sources are provided, each having a supply and return terminal, which supply and return equal amounts of current at any given time. The constant current source(s) are coupled to the electrodes in such a manner that each supply terminal and each return terminal is coupled to no more than the electrodes of a single one of the functional sets, if any, or to a single one of the electrodes not included in one of the functional sets.
    Type: Application
    Filed: April 13, 2010
    Publication date: August 16, 2012
    Applicant: Research Foundation of the City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Varun Bansal, Lucas C Parra, Xiang Zhou
  • Publication number: 20110319975
    Abstract: An electrode assembly for neuro-cranial stimulation includes an electrode, a conductive gel, and an adapter including an interior compartment for positioning the electrode relative to the adapter and for receiving and retaining the conductive gel. The conductive gel contacts the electrode along an electrode-gel interface. An orifice at one end of the interior compartment and adjacent to a positioning surface of the adapter for positioning the electrode assembly against a skin surface of a user enables the conductive gel is able to contact the skin surface of the user to define a gel-skin interface, such that a minimum distance between the electrode-gel interface and the gel-skin interface is maintained between 0.25 cm and 1.3 cm. An electrode assembly mounting apparatus is provided for adjustably positioning a plurality of electrode assemblies against target positions on the cranium.
    Type: Application
    Filed: December 30, 2009
    Publication date: December 29, 2011
    Applicant: Research Foundation of the City University of New York
    Inventors: Johnson Ho, Preet Minhas, Marom Bikson, Abhishek Datta, Varun Bansal, Jinal Patel, Dan Steingart, Jorge Vega, Lucas Parra
  • Publication number: 20110144716
    Abstract: There is provided method and apparatus for enhancing focality of neurocranial electrostimulation, including: providing a first plurality of electrodes having at least one electrode; providing a second plurality of electrodes having at least two electrodes; locating the first and the second plurality of electrodes on cranium of a subject and supplying electric current of opposite polarities to the first and the second plurality of electrodes. At least one electrode of the first plurality of electrodes is surrounded by at least two electrodes of the second plurality of electrodes. The enhanced focal stimulation may be used to treat ailments or augment cognitive performance. There are also provided methods for treating brain related ailments and performance augmentation.
    Type: Application
    Filed: September 18, 2008
    Publication date: June 16, 2011
    Applicant: Research Foundation of The City University of New York
    Inventors: Marom Bikson, Abhishek Datta, Fortunato Battaglia, Maged Elwassif