Abstract: The invention relates to storage-stable pigmented formulations containing isocyanate groups, comprising at least one pigment a., at least one component b. containing isocyanate groups, at least one wetting agent and/or dispersant c., at least one isocyanate group-containing grinding resin d. and optionally solvents, wherein the formulation has a viscosity increase of less than 500% after storage at 50° C. over a period of at least 3 days. The invention also relates to the preparation of such formulations and to the use thereof.

Abstract: The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.

Abstract: Disclosed is a biogel nanosensor for detection of an analyte that includes an acryloyl or methacryloyl modified hydrogel and nucleic acid amplification reagents in picoliter or nanoliter volume in the form of microarray. Also disclosed are methods of making the disclosed biogel nanosensor, and methods of using the biogel nanosensors.

Abstract: The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.

Abstract: The instant disclosure generally relates to a composition for treating or coloring keratin fibers, the composition comprising at least one bio-based polymer and optionally a crosslinker. The composition may also comprise pigment microparticles. The composition formed and set in situ as a solid linked coating has a substantially permanent pigment lastingness and minimally alters the keratin fibers.

Abstract: Disclosed is a biogel nanosensor for detection of an analyte that includes an acryloyl or methacryloyl modified hydrogel and nucleic acid amplification reagents in picoliter or nanoliter volume in the form of microarray. Also disclosed are methods of making the disclosed biogel nanosensor, and methods of using the biogel nanosensors.

Abstract: The invention relates to storage-stable pigmented formulations containing isocyanate groups, comprising at least one pigment a., at least one component b. containing isocyanate groups, at least one wetting agent and/or dispersant c., at least one isocyanate group-containing grinding resin d. and optionally solvents, wherein the formulation has a viscosity increase of less than 500% after storage at 50° C. over a period of at least 3 days.

Abstract: The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.

Abstract: The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.

Abstract: The present invention relates to the use of BMW Rep-protein as a biomarker for colon cancer.

Abstract: The invention relates to storage-stable pigmented formulations containing isocyanate groups, comprising at least one pigment a., at least one component b. containing isocyanate groups, at least one wetting agent and/or dispersant c., at least one grind resin d. and optionally solvents, wherein the formulation has a viscosity increase of less than 500% after storage at 50° C. over a period of at least 3 days. The invention also relates to the production of such formulations and to the use thereof.

Abstract: The present invention provides novel compounds that target thrombocyte activity or aggregation capacity through cellular components for the treatment of diseases associated with Non-Alcoholic Fatty Liver Disease (NAFLD). The invention provides these compounds for treating non-alcoholic steatohepatitis (NASH), a progressed stage of NAFL (non-alcoholic fatty liver), in order to avoid the development of liver cirrhosis and Hepatocellular Carcinoma (HCC). Further provided are pharmaceutical compositions, comprising the compounds of the invention, and methods for screening new NASH therapeuticals.

Abstract: An electric machine (1) and to a method for producing the machine (1), including a housing (2) and a stator (3) accommodated therein, as well as at least one rotor (4) arranged radially inside the stator (3), a plastic body (7) that at least radially surrounds the outside of a soft-magnetic core (5) of the stator (3), and a cooling device (10) located between the stator (3) and the housing (2) is provided. In order to improve the cooling device (10), at least one recess (11) that conveys a cooling medium is created between the housing (2) and the stator (3) at least partially in the outer circumferential surface of the plastic body (7).

Abstract: Disclosed herein a rotational type foil trap that is capable of avoiding the transmission rate of the EUV light to be lowered even when the EUV light source operates with the high input power and also suppressing the temperature increase of the foil to attain a sufficient life duration. In the rotational type foil trap, one end of each of foils is inserted into each of a plurality of grooves provided on a side face of a center support, and the center support and the each of the foils are fixed together by brazing.

Abstract: Disclosed herein a rotational type foil trap that is capable of avoiding the transmission rate of the EUV light to be lowered even when the EUV light source operates with the high input power and also suppressing the temperature increase of the foil to attain a sufficient life duration. In the rotational type foil trap, one end of each of foils is inserted into each of a plurality of grooves provided on a side face of a center support, and the center support and the each of the foils are fixed together by brazing.

Abstract: An electric machine (1) and to a method for producing the machine (1), including a housing (2) and a stator (3) accommodated therein, as well as at least one rotor (4) arranged radially inside the stator (3), a plastic body (7) that at least radially surrounds the outside of a soft-magnetic core (5) of the stator (3), and a cooling device (10) located between the stator (3) and the housing (2) is provided. In order to improve the cooling device (10), at least one recess (11) that conveys a cooling medium is created between the housing (2) and the stator (3) at least partially in the outer circumferential surface of the plastic body (7).

Abstract: The present disclosure relates to polymer particles comprising a polymer matrix having a coating of an inorganic semimetal oxide or metal oxide, wherein the polymer matrix has at least one first functional group A and at least one second functional group B, both functional groups A and B being able to enter into at least one covalent bond with one another, functional group A being selected from the group consisting of an azide group, C—C double bond, C—C triple bond, aldehyde group, ketone group, imine group, thioketone group and thiol group, and functional group B being selected from the group consisting of a C—C double bond, C—C triple bond, C—N triple bond, diene group, thiol group and amine group.

Abstract: The present disclosure relates to polymer particles comprising a polymer matrix having a coating of an inorganic semimetal oxide or metal oxide, wherein the polymer matrix has at least one first functional group A and at least one second functional group B, both functional groups A and B being able to enter into at least one covalent bond with one another, functional group A being selected from the group consisting of an azide group, C —C double bond, C —C triple bond, aldehyde group, ketone group, imine group, thioketone group and thiol group, and functional group B being selected from the group consisting of a C —C double bond, C —C triple bond, C —N triple bond, diene group, thiol group and amine group.

Abstract: A method of cleaning at least one optical component of at least one irradiation device having at least one radiation source in a vacuum chamber. The source generates in particular extreme ultraviolet and/or soft X-ray radiation whose rays are guided via the optical component onto a workpiece to be treated, during which the optical component is at least partly polluted because of an inorganic substance introduced by the radiation source. A least one reaction partner that is substantially translucent or transparent to the rays is introduced via a feeder device in dependence on the prevailing reaction conditions. The reaction partner reacts chemically with the polluting deposits so as to remove them from the optical component.

Abstract: The invention relates to an improved EUV generating device having a contamination captor for “catching” contamination and/or debris caused by corrosion or otherwise unwanted reactions of the tin bath.