Patents by Inventor Adam Looker
Adam Looker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250058522Abstract: Aspects of the disclosure include a pump assembly comprising a plurality of pumps (e.g. syringe pumps) positioned in a radial array on a mounting bracket. In embodiments, each syringe pump of the plurality of syringe pumps comprises a housing comprising a syringe retainer and a plunger driver. The pump assembly serves to minimize internal volume when used as part of a multi-channel microfluidic bioprinting system.Type: ApplicationFiled: December 16, 2022Publication date: February 20, 2025Inventors: Simon BEYER, Sebastian STEINER, Florentin WILFART, Shaun LAIDLOW, Keddie BROWN, Zhensong XU, Henrik PERSSON, Navid HAKIMI, Adam LOOKER
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Publication number: 20240336614Abstract: The disclosure provides compounds useful for treating alpha-1 antitrypsin deficiency (AATD), according to formula (I): tautomers thereof, pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable salts of the tautomers, deuterated derivatives of the compounds, deuterated derivatives of the tautomers, and deuterated derivatives of the salts, solid forms of those compounds and processes for making those compounds.Type: ApplicationFiled: October 16, 2023Publication date: October 10, 2024Inventors: Upul Keerthi BANDARAGE, Cavan McKeon BLIGH, Diane BOUCHER, Michael John BOYD, Michael Aaron BRODNEY, Michael Philip CLARK, Veronique DAMAGNEZ, Lev Tyler Dewey FANNING, Robert Francis FIMOGNARI, Gabrielle Simone FLEMING, Kevin James GAGNON, Pedro Manuel GARCIA BARRANTES, Robert Daniel GIACOMETTI, Simon GIROUX, Ronald Lee GREY, JR., Samantha GUIDO, Amy Beth HALL, Sarah Carol HOOD, Dennis James HURLEY, Mac Arthur JOHNSON, JR., Peter Jones, Sarathy KESAVAN, Mei-Hsiu LAI, Siying LIU, Adam LOOKER, Brad MAXWELL, John Patrick MAXWELL, Ales MEDEK, Philippe Marcel NUHANT, Kirk Alan OVERHOFF, Setu RODAY, Stefanie ROEPER, Steven M. RONKIN, Rupa SAWANT, Yi SHI, Muna SHRESTHA, Marisa SPOSATO, Kathy STAVROPOULOS, Rebecca Jane SWETT, Timothy Lewis TAPLEY, Qing TANG, Stephen THOMSON, Jinwang XU, Mariam ZAKY, Kevin Michael COTTRELL
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Publication number: 20240246762Abstract: A storage system includes a three dimensional structure including an array of cells including a plurality of cells configured to retain individual storage bins for retrieval, the array of cells forming a plurality of storage levels located at different elevations within the three dimensional structure, respectively. A second plurality of cells positioned relative to one another to form a plurality of vertical shafts located within the three dimensional structure. The storage system includes a plurality of towerbots located atop the three dimensional structure. Each of the towerbots is configured to move laterally atop the three dimensional structure between multiple different locations atop the three dimensional structure including at least a first position located above a first vertical shaft included in the plurality of vertical shafts and a second position located above a second vertical shaft included in the plurality of vertical shafts.Type: ApplicationFiled: September 1, 2023Publication date: July 25, 2024Inventors: Kirk Whittemore, Nikko Pianetto, Lincoln Cavalieri, Adam Looker
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Patent number: 12024491Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.Type: GrantFiled: June 20, 2023Date of Patent: July 2, 2024Assignee: Vertex Pharmaceuticals IncorporatedInventors: Berenice Lemercier Lewandowski, Robert Lewis, Adam Looker, Adam Morgan, Stefanie Roeper, Michael Ryan, Juan Gabriel Solsona Rocabert, Nathan Wilde
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Publication number: 20240182191Abstract: A delivery drone includes an airframe, a drive module joined to the airframe, a storage module joined the drive module and a plurality of motors joined to the airframe. The storage module includes a housing defining an internal cavity in which a parcel may be situated. The delivery drone is selectively navigable between and dockable with a logistics tower and a drone port mounted to a residential or commercial structure. A drone loader is situated in a secondary vertical shaft of the logistics tower and includes a plurality of drone docks, each drone dock being engageable with a delivery drone. The logistics tower includes a plurality of tower drone ports through which the delivery drones traverse to access the elevator shafts and the secondary vertical shafts of the logistics tower.Type: ApplicationFiled: April 1, 2022Publication date: June 6, 2024Inventors: Lincoln Cavalieri, Adam Looker, Paul Sandin
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Publication number: 20240166607Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.Type: ApplicationFiled: June 20, 2023Publication date: May 23, 2024Inventors: Berenice Lemercier Lewandowski, Robert Lewis, Adam Looker, Adam Morgan, Stefanie Roeper, Michael Ryan, Juan Gabriel Solsona Rocabert, Nathan Wilde
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Patent number: 11884672Abstract: The disclosure provides compounds useful for treating alpha-1 antitrypsin deficiency (AATD), according to formula (I): tautomers thereof, pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable salts of the tautomers, deuterated derivatives of the compounds, deuterated derivatives of the tautomers, and deuterated derivatives of the salts, solid forms of those compounds and processes for making those compounds.Type: GrantFiled: May 13, 2020Date of Patent: January 30, 2024Assignee: Vertex Pharmaceuticals IncorporatedInventors: Upul Keerthi Bandarage, Cavan McKeon Bligh, Diane Boucher, Michael John Boyd, Michael Aaron Brodney, Michael Philip Clark, Veronique Damagnez, Lev Tyler Dewey Fanning, Robert Francis Fimognari, Gabrielle Simone Fleming, Kevin James Gagnon, Pedro Manuel Garcia Barrantes, Robert Daniel Giacometti, Simon Giroux, Ronald Lee Grey, Jr., Samantha Guido, Amy Beth Hall, Sarah Carol Hood, Dennis James Hurley, Mac Arthur Johnson, Jr., Peter Jones, Sarathy Kesavan, Mei-Hsiu Lai, Siying Liu, Adam Looker, Brad Maxwell, John Patrick Maxwell, Ales Medek, Philippe Marcel Nuhant, Kirk Alan Overhoff, Setu Roday, Stefanie Roeper, Steven M. Ronkin, Rupa Sawant, Yi Shi, Muna Shrestha, Marisa Sposato, Kathy Stavropoulos, Rebecca Jane Swett, Timothy Lewis Tapley, Qing Tang, Stephen Thomson, Jinwang Xu, Mariam Zaky, Kevin Michael Cottrell
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Publication number: 20230279010Abstract: This disclosure provides large-scale processes for preparing a modulator of alpha-1 antitrypsin (AAT) activity that may be useful for treating alpha-1 antitrypsin deficiency (AATD), such as 4-(5-(4-fluorophenyl)-6-(tetrahydro-2H-pyran -4-yl)-1,5-dihydropyrrolo[2,3-f]indazol-7-yl)benzoic acid (Compound 1), 3-[5-(4-fluorophenyl)-6-isopropyl-1H-pyrrolo[2,3-f]inda-zol-7-yl]propanoic acid (Compound 2), or a pharmaceutically acceptable salt of any of the foregoing.Type: ApplicationFiled: July 26, 2021Publication date: September 7, 2023Inventors: Cavan McKeon BLIGH, Robert Daniel GIACOMETTI, Cristian HARRISON, Stephen W. LAWS, Adam LOOKER, Stefanie ROEPER
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Publication number: 20230265080Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).Type: ApplicationFiled: February 9, 2023Publication date: August 24, 2023Inventors: Upul Keerthi BANDARAGE, Cavan McKeon BLIGH, Michael John BOYD, Diane M. BOUCHER, Michael Aaron BRODNEY, Veronique DAMAGNEZ, Lev Tyler DEWEY FANNING, Mary Elizabeth ECCLES, Robert Francis FIMOGNARI, JR., Kevin James GAGNON, Pedro M. GARCIA BARRANTES, Simon GIROUX, Ronald Lee GREY, JR., Amy Beth HALL, Sarah Carol HOOD, Dennis James HURLEY, Joshua Kennedy HUSSEY, Mac Arthur JOHNSON, JR., Peter JONES, Sarathy KESAVAN, Adam LOOKER, Brad D. MAXWELL, John Patrick MAXWELL, Ales MEDEK, Mettachit NAVAMAL, Philippe Marcel NUHANT, Setu RODAY, Stefanie ROEPER, Rupa SAWANT, Yi SHI, Rebecca Jane SWETT, Qing TANG, Timothy Lewis TAPLEY, Stephen A. THOMSON, Michael WALDO, Jinwang XU, Kevin Michael COTTRELL
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Patent number: 11708331Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.Type: GrantFiled: November 30, 2018Date of Patent: July 25, 2023Assignee: Vertex Pharmaceuticals IncorporatedInventors: Berenice Lemercier Lewandowski, Robert Lewis, Adam Looker, Adam Morgan, Stefanie Roeper, Michael Ryan, Juan Gabriel Solsona Rocabert, Nathan Wilde
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Publication number: 20230118968Abstract: A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.Type: ApplicationFiled: September 26, 2022Publication date: April 20, 2023Inventors: Francesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
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Patent number: 11623924Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).Type: GrantFiled: October 4, 2019Date of Patent: April 11, 2023Assignee: Vertex Pharmaceuticals IncorporatedInventors: Upul Keerthi Bandarage, Cavan McKeon Bligh, Michael John Boyd, Diane M. Boucher, Michael Aaron Brodney, Veronique Damagnez, Lev Tyler Dewey Fanning, Mary Elizabeth Eccles, Robert Francis Fimognari, Jr., Kevin James Gagnon, Pedro M. Garcia Barrantes, Simon Giroux, Ronald Lee Grey, Jr., Amy Beth Hall, Sarah Carol Hood, Dennis James Hurley, Joshua Kennedy Hussey, Mac Arthur Johnson, Jr., Peter Jones, Sarathy Kesavan, Adam Looker, Brad D. Maxwell, John Patrick Maxwell, Ales Medek, Mettachit Navamal, Philippe Marcel Nuhant, Setu Roday, Stefanie Roeper, Rupa Sawant, Yi Shi, Rebecca Jane Swett, Qing Tang, Timothy Lewis Tapley, Stephen A. Thomson, Michael Waldo, Jinwang Xu, Kevin Michael Cottrell
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Patent number: 11456071Abstract: A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.Type: GrantFiled: March 21, 2019Date of Patent: September 27, 2022Assignee: HemoSonics LLCInventors: Francesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
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Publication number: 20220194699Abstract: A logistics tower includes a vertical storage cell column, a vertical retrieval system and a horizontal shuttle system. The vertical storage cell column includes an elevator shaft extending therethrough and a plurality of storage modules arranged around the elevator shaft. The vertical retrieval system includes a winch and a robotic bin handier. The robotic bin handler is moveably by the winch within the elevator shaft of the vertical storage cell column. The robotic bin handler includes a carnage assembly that extends inwardly and outwardly therefrom to access and retrieve storage bins from the storage modules arranged around the elevator shaft. The carriage assembly includes a gripping assembly that selectively couples and decouples the storage bin to the carriage of the robotic bin handler. The vertical retrieval system lowers the storage bin coupled to the carriage assembly to a. robotic shuttle situated on the horizontal shuttle system.Type: ApplicationFiled: April 9, 2020Publication date: June 23, 2022Inventors: ADAM LOOKER, JONATHAN LIN, STEVEN LECKENBY, LINCOLN CAVALIERI, PAUL SANDIN
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Publication number: 20210179587Abstract: Novel compounds, compositions, and methods of using and preparing the same, which may be useful for treating alpha-1 antitrypsin deficiency (AATD).Type: ApplicationFiled: October 4, 2019Publication date: June 17, 2021Inventors: Upul Keerthi BANDARAGE, Cavan McKeon BLIGH, Michael John BOYD, Diane M. BOUCHER, Michael Aaron BRODNEY, Veronique DAMAGNEZ, Lev Tyler DEWEY FANNING, Mary Elizabeth ECCLES, Robert Francis FIMOGNARI, JR., Kevin James GAGNON, Pedro M. GARCIA BARRANTES, Simon GIROUX, Ronald Lee GREY, JR., Amy Beth HALL, Sarah Carol HOOD, Dennis James HURLEY, Joshua Kennedy HUSSEY, Mac Arthur JOHNSON, JR., Peter JONES, Sarathy KESAVAN, Adam LOOKER, Brad D. MAXWELL, John Patrick MAXWELL, Ales MEDEK, Mettachit NAVAMAL, Philippe Marcel NUHANT, Setu RODAY, Stefanie ROEPER, Rupa SAWANT, Yi SHI, Rebecca Jane SWETT, Qing TANG, Timothy Lewis TAPLEY, Stephen A. THOMSON, Michael WALDO, Jinwang XU
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Publication number: 20200361939Abstract: The disclosure provides compounds useful for treating alpha-1 antitrypsin deficiency (AATD), according to formula (I): tautomers thereof, pharmaceutically acceptable salts of the compounds, pharmaceutically acceptable salts of the tautomers, deuterated derivatives of the compounds, deuterated derivatives of the tautomers, and deuterated derivatives of the salts, solid forms of those compounds and processes for making those compounds.Type: ApplicationFiled: May 13, 2020Publication date: November 19, 2020Inventors: Upul Keerthi BANDARAGE, Cavan McKeon BLIGH, Diane BOUCHER, Michael John BOYD, Michael Aaron BRODNEY, Michael Philip CLARK, Veronique DAMAGNEZ, Lev Tyler Dewey FANNING, Robert Francis FIMOGNARI, Gabrielle Simone FLEMING, Kevin James GAGNON, Pedro Manuel GARCIA BARRANTES, Robert Daniel GIACOMETTI, Simon GIROUX, Ronald Lee GREY, Jr., Samantha GUIDO, Amy Beth HALL, Sarah Carol HOOD, Dennis James HURLEY, Mac Arthur JOHNSON, Jr., Peter Jones, Sarathy KESAVAN, Mei-Hsiu LAI, Siying LIU, Adam LOOKER, Brad MAXWELL, John Patrick MAXWELL, Ales MEDEK, Philippe Marcel NUHANT, Kirk Alan OVERHOFF, Setu RODAY, Stefanie ROEPER, Steven M. RONKIN, Rupa SAWANT, Yi SHI, Muna SHRESTHA, Marisa SPOSATO, Kathy STAVROPOULOS, Rebecca Jane SWETT, Timothy Lewis TAPLEY, Qing TANG, Stephen THOMSON, Jinwang XU, Mariam ZAKY
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Publication number: 20200290972Abstract: The disclosure provides processes for synthesizing compounds for use as CFTR modulators.Type: ApplicationFiled: November 30, 2018Publication date: September 17, 2020Inventors: Berenice Lemercier Lewandowski, Robert Lewis, Adam Looker, Adam Morgan, Stefanie Roeper, Michael Ryan, Juan Gabriel Solsona Rocabert, Nathan Wilde
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Publication number: 20190244692Abstract: A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.Type: ApplicationFiled: March 21, 2019Publication date: August 8, 2019Inventors: Francesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
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Patent number: 10147152Abstract: A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.Type: GrantFiled: April 8, 2011Date of Patent: December 4, 2018Assignee: HemoSonics, LLCInventors: Francesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
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Patent number: 9655813Abstract: A stylus and a treatment head for use with a medical device for imparting a force is provided. The stylus allows a practitioner to maintain focus on the treatment location while adjusting placement and force. This is because a light signal is emitted in the vicinity of the distal end of the stylus, proximate the treatment location on the patient. Alternatively, an audible or a tactile signal is employed for feedback. As a safety feature, the stylus is provided with means to allow it to collapse at forces above the acceptable limit.Type: GrantFiled: December 8, 2011Date of Patent: May 23, 2017Assignee: KKT International Ltd.Inventors: Stephen Leckenby, Adam Looker, Augustus Mercer, Trevor Moat
