Patents by Inventor Adam Looker

Adam Looker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stylus and treatment head for use with a medical device
    Patent number: 9655813
    Abstract: A stylus and a treatment head for use with a medical device for imparting a force is provided. The stylus allows a practitioner to maintain focus on the treatment location while adjusting placement and force. This is because a light signal is emitted in the vicinity of the distal end of the stylus, proximate the treatment location on the patient. Alternatively, an audible or a tactile signal is employed for feedback. As a safety feature, the stylus is provided with means to allow it to collapse at forces above the acceptable limit.
    Type: Grant
    Filed: December 8, 2011
    Date of Patent: May 23, 2017
    Assignee: KKT International Ltd.
    Inventors: Stephen Leckenby, Adam Looker, Augustus Mercer, Trevor Moat
  • MODULATORS FOR ATP-BINDING CASSETTE TRANSPORTERS
    Publication number: 20160166540
    Abstract: Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
    Type: Application
    Filed: January 11, 2016
    Publication date: June 16, 2016
    Inventors: Adam Looker, Benjamin Joseph Littler, Anusuya Choudhury, Christian Harrison, Ravikanth Veluri, Michael P. Ryan, Licong Jiang, Eduard Luss-Lusis
  • Modulators of ATP-binding cassette transporters
    Patent number: 9254291
    Abstract: Compounds of the present invention and pharmaceutically acceptable compositions thereof, are useful as modulators of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including Cystic Fibrosis Transmembrane Conductance Regulator (“CFTR”). The present invention also relates to methods of treating ABC transporter mediated diseases using compounds of the present invention.
    Type: Grant
    Filed: November 8, 2012
    Date of Patent: February 9, 2016
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Adam Looker, Benjamin Joseph Littler, Anusuya Choudhury, Cristian Harrison, Ravikanth Veluri, Michael P. Ryan, Licong Jiang, Eduard Luss-Lusis
  • PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
    Publication number: 20150284388
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Application
    Filed: June 17, 2015
    Publication date: October 8, 2015
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • Processes and intermediates for producing azaindoles
    Patent number: 9090614
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: July 28, 2015
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
    Publication number: 20150099884
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Application
    Filed: December 15, 2014
    Publication date: April 9, 2015
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • Processes and intermediates for producing azaindoles
    Patent number: 8946425
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Grant
    Filed: June 25, 2014
    Date of Patent: February 3, 2015
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jur{hacek over (c)}ík, Beatriz Dominguez Olmo
  • Processes and intermediates
    Patent number: 8871904
    Abstract: The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
    Type: Grant
    Filed: February 14, 2013
    Date of Patent: October 28, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Minzhang Chen, John E. Cochran, Adam Looker, Valdas Jurkauskas
  • PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
    Publication number: 20140309421
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Application
    Filed: June 25, 2014
    Publication date: October 16, 2014
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • Processes and intermediates for producing azaindoles
    Patent number: 8796453
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Grant
    Filed: July 12, 2013
    Date of Patent: August 5, 2014
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
    Publication number: 20130303764
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Application
    Filed: July 12, 2013
    Publication date: November 14, 2013
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcik, Beatriz Dominguez Olmo
  • Processes and intermediates for producing azaindoles
    Patent number: 8513414
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Grant
    Filed: July 3, 2012
    Date of Patent: August 20, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcik, Beatriz Dominguez Olmo
  • PROCESSES AND INTERMEDIATES FOR PRODUCING AZAINDOLES
    Publication number: 20130102782
    Abstract: The present invention relates to processes and intermediates for the preparation of compounds useful as inhibitors of Janus kinases (JAK).
    Type: Application
    Filed: July 3, 2012
    Publication date: April 25, 2013
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Young Chun Jung, Derek Magdziak, Adam Looker, Billie J. Kline, Václav Jurcík, Beatriz Dominguez Olmo
  • Processes and intermediates
    Patent number: 8399615
    Abstract: The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: March 19, 2013
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Gerald J. Tanoury, Minzhang Chen, John E. Cochran, Adam Looker, Valdas Jurkauskas
  • SOLID FORMS OF N-[2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL]-1,4-DIHYDRO-4-OXOQUINOLINE-3-CARBOXAMIDE
    Publication number: 20120165372
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Application
    Filed: March 6, 2012
    Publication date: June 28, 2012
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian Harrison, Adam Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxypheny1]-1,4-dihydro-4-oxoquinoline-3-carboxamide
    Patent number: 8163772
    Abstract: Solid forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide are described herein, including crystalline forms thereof.
    Type: Grant
    Filed: September 15, 2008
    Date of Patent: April 24, 2012
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: John DeMattei, Yushi Feng, Cristian Harrison, Adam Looker, Praveen Mudunuri, Stefanie Roeper, Yuegang Zhang
  • Hemostatic Parameter Display
    Publication number: 20110252352
    Abstract: A system for displaying a plurality of hemostatic indexes is disclosed. The system includes a communication receiver configured to receive the hemostatic indexes and a graphical user interface (GUI) connected to the communication receiver and configured to simultaneously display the hemostatic indexes. The hemostatic indexes are derived from a plurality of independent measurements, such as the mechanical measurements determined using the sonorheometry systems and processes.
    Type: Application
    Filed: April 8, 2011
    Publication date: October 13, 2011
    Applicant: HEMOSONICS LLC
    Inventors: Francesco Viola, William F. Walker, Gregory V. Browne, Adam Looker, Bryan Roy, Bjarne Hansen
  • Processes for preparing biaryl ureas and analogs thereof
    Patent number: 7777048
    Abstract: The present invention relates to processes for preparing biaryl ureas derivatives and analogs thereof. The invention also provides compounds useful as intermediates in the processes of the present invention. The process is useful for preparing compounds that inhibit IMPDH.
    Type: Grant
    Filed: May 5, 2009
    Date of Patent: August 17, 2010
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Graham Ansell, Todd Blythe, Andrew Jones, Benjamin Littler, Adam Looker, Philip Nyce, John Snoonian
  • Chest pad for CPR feedback device
    Patent number: D689614
    Type: Grant
    Filed: September 30, 2011
    Date of Patent: September 10, 2013
    Assignee: Physio-Control, Inc.
    Inventors: Gregory V. Browne, Adam Looker, Ryan D. Lee, Sarah A. Smith, Corey J. Centen, Maegan P. Wilkinson, Richard C. Nova, Cathlene Durand Buchanan, Chad Alan Follmar, David Mark VandeRiet, Seth Paul Lynch, Mark Allen Catron, Chad Clayton Walters
  • Chest pad for CPR feedback device
    Patent number: D764059
    Type: Grant
    Filed: July 18, 2013
    Date of Patent: August 16, 2016
    Assignee: PHYSIO-CONTROL, INC.
    Inventors: Gregory V. Browne, Adam Looker, Ryan D. Lee, Sarah A. Smith, Corey J. Centen, Maegan P. Wilkinson, Richard C. Nova, Cathlene Durand Buchanan, Chad Alan Follmar, David Mark VandeRiet, Seth Paul Lynch, Mark Allen Catron, Chad Clayton Walters