Abstract: A face mask for use with Self Contained Underwater Breathing Apparatus (SCUBA) diving equipment which forms a sealed enclosure about the user's eyes and nose but not the mouth has a frame with sides and a clear viewing port and a means to introduce air flow into the enclosure. The flow of air into the enclosure is metered by a metering device which may be an orifice or a manually operated valve or an automated valve using a timer or sensors which monitor and respond to conditions such as heat and humidity. The metering device may be controlled by a control means. When the control means is activated, pressurized air flows into the enclosure. In one embodiment, air flow is directed against the inner surface of the viewing port to remove moisture and heat which may cause the viewing port to fog. The mask may be equipped with a relief valve to allow incoming pressurized air flow to force trapped liquid out of the enclosure.

Abstract: The invention relates to 3-substituted-1H-pyrrolo[2,3-b]pyridine, and 3-substituted-1H-pyrrolo[3,2-b]pyridine compounds of the Formula 1: or a pharmaceutically acceptable salt thereof, wherein the constituent variables are as defined herein, compositions comprising the compounds, and methods for making and using the compounds.

Abstract: A horticultural applicator (10) device comprising a raft (12) having a means for applying a substance to plants (14) and a means to drag the raft (22). The raft (12) is dragged over the top of the plants and the means for applying the substance (14) mounted to the raft (12) applies the substance onto said plants.

Abstract: A monitoring system includes a transmitter (102) with two transmit modules (208, 210) and a receiver (104) with two receive modules (212, 214). Each of the transmit modules (208, 210) generates an optical signal modulated at a unique frequency. The optical signals are transmitted across a roadway (112) and are detected by the receive modules (212, 214). When a vehicle (110) moves between the transmitter (102) and receiver (104), the optical signals are blocked. The receiver (104) generates timestamped make and break events corresponding to the blocking and unblocking of the signals, and these are used to determine parameters for the vehicle (110) such as velocity and vehicle classification. Because each signal is modulated at a different frequency, each receive module (212, 214) can distinguish the signals received from each of the transmit modules (208, 210), allowing the lane position of the vehicle (110) in a multi-lane roadway (112) to be determined.

Abstract: The present invention relates to pyrimidine sulfonamide analogs, methods of making pyrimidine sulfonamide analogs, compositions comprising a pyrimidine sulfonamide analog, and methods for treating canonical Wnt-?-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of a pyrimidine sulfonamide analog.

Abstract: The present invention relates to heteroaryl/aryl pyrimidine analogs, methods of making aryl/heteroaryl pyrimidine analogs, compositions comprising a aryl/heteroaryl pyrimidine analog, and methods for treating canonical Wnt-?-catenin cellular messaging system-related disorders comprising administering to a subject in need thereof an effective amount of a heteroaryl/aryl pyrimidine analog.

Abstract: Aspects of the invention relate to a system and method for actively controlling compressor clearances in a turbine engine by passing a thermal fluid in heat exchanging relation through a compressor vane carrier. During some operational conditions, such as hot restart or spin cool, it may be desirable to heat the vane carrier to enlarge or at least prevent a decrease in compressor clearances. In such cases, a heated thermal fluid can be provided by reclaiming residual exhaust energy from a heat recovery steam generator. At any condition where improved performance is desired, such as at base load operation, the vane carrier can be cooled to minimize compressor clearances. A cooled thermal fluid can be bleed air from an upstream portion of the compressor, water-cooled high pressure bleed air from a downstream portion of the compressor, or feed water from the bottoming cycle in a combined cycle engine.

Abstract: The present invention relates to Imidazolopyrimidine Analogs, methods of making Imidazolopyrimidine Analogs, compositions comprising an Imidazolopyrimidine Analog, and methods for treating or preventing a PI3K-related disorder comprising administering to a subject in need thereof an effective amount of an Imidazolopyrimidine Analog. The invention also relates to methods for treating or preventing mTOR-related disorders comprising administering to a subject in need thereof an effective amount of an Imidazolopyrimidine Analog.

Abstract: A system and method for generating simulated wiring connections between first I/O terminals of a semiconductor device and second I/O terminals of a carrier. The method comprises identifying a plurality of first factors and instances of each first factor relating to a semiconductor device and identifying a plurality of second factors and instances of each second factor relating to a carrier. The first and second factors are associated with each other on a one-to-one basis. The instances of each first factor are correlated to the instances of each associated second factor on a one-to-one basis. A simulated wiring connection automatically is generated between each first I/O terminal and a matching second I/O terminal, subject to an identified instance of each first factor of each first I/O terminal being correlated to an identified instance of the associated second factor of the matching second I/O terminal.

Abstract: A device for assisting thought processes in decision making. The device is a book having a front cover bearing a title in characters and a rear cover bearing the title but wherein the characters comprising the title are inverted with respect to the front cover. Thus, the book may be opened sensibly from either the front or the back. A plurality of pages, each page bearing self-contained text, are disposed between the front and rear covers with the text inverted on alternate pages. A person contemplates a problem then opens the book either from the front or the rear to reveal a random page. The text that appears in non-inverted characters on the exposed page is read to provide guidance in solving the problem.

Abstract: A monitoring system includes a transmitter (102) with two transmit modules (208, 210) and a receiver (104) with two receive modules (212, 214). Each of the transmit modules (208, 210) generates an optical signal modulated at a unique frequency. The optical signals are transmitted across a roadway (112) and are detected by the receive modules (212, 214). When a vehicle (110) moves between the transmitter (102) and receiver (104), the optical signals are blocked. The receiver (104) generates timestamped make and break events corresponding to the blocking and unblocking of the signals, and these are used to determine parameters for the vehicle (110) such as velocity and vehicle classification. Because each signal is modulated at a different frequency, each receive module (212, 214) can distinguish the signals received from each of the transmit modules (208, 210), allowing the lane position of the vehicle (110) in a multi-lane roadway (112) to be determined.

Abstract: This invention concerns the treatment of smooth muscle spasticity or excess muscle contraction such as urge urinary incontinence with a compound of the formula wherein: R1 and R2 are independently straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbons atoms, or cycloalkyl of 3 to 6 carbons atoms where R2 may be substituted by F, Cl, Br, I, OH, NH2, cyano, C1-C6 alkoxy, C1-C6alkylthio, COOH or COOC1-C6 alkyl; R3 is an aryl or heteroaryl as defined herein, optionally substituted with 0 to 4 groups selected independently from C1-C6 alkyl, C1-C6 alkoxy, cyano, F, Cl, Br, C1-C6 alkylthio, CO2R1, CONH2, OH, NH2, and NO2; n is 0 or 1; R4 is a straight chain alkyl group of 1 to 10 carbons atoms, a branched alkyl of 3 to 10 carbons, or a cycloalkyl of 3 to 10 carbons; and all crystalline forms and the pharmaceutically acceptable salts thereof.

Abstract: This invention concerns the treatment of smooth muscle spasticity or excess muscle contraction such as urge urinary incontinence with a compound of the formula 1

Abstract: This invention concerns the treatment of smooth muscle spasticity or excess muscle contraction such as urge urinary incontinence with a compound of the formula wherein: R1 and R2 are independently straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbons atoms, or cycloalkyl of 3 to 6 carbons atoms where R1 and R2 may be substituted by F, Cl, Br, I, OH, NH2, cyano, C1-C6 alkoxy, C1-C6alkylthio, COOH or COOC1-C6 alkyl; R3 is an aryl or heteroaryl as defined herein, optionally substituted with 0 to 4 groups selected independently from C1-C6 alkyl, C1-C6 alkoxy, cyano, F, Cl, Br, C1-C6 alkylthio, CO2R1, CONH2, OH, NH2, and NO2; n is 0 or 1; R4 is a straight chain alkyl group of 1 to 10 carbons atoms, a branched alkyl of 3 to 10 carbons, or a cycloalkyl of 3 to 10 carbons; and all crystalline forms and the pharmaceutically acceptable salts thereof.

Abstract: This invention concerns the treatment of smooth muscle spasticity or excess muscle contraction such as urge urinary incontinence with a compound of the formula wherein: R1 and R2 are independently straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbons atoms, or cycloalkyl of 3 to 6 carbons atoms where R1 R2 may be substituted by F, Cl, Br, I, OH, NH2, cyano, C1-C6 alkoxy, C1-C6alkylthio, COOH or COOC1-C6 alkyl; R3 is an aryl or heteroaryl as defined herein, optionally substituted with 0 to 4 groups selected independently from C1-C6 alkyl, C1-C6 alkoxy, cyano, F, Cl, Br, C1-C6 alkylthio, CO2R1, CONH2, OH, NH2, and NO2; n is 0 or 1; R4 is a straight chain alkyl group of 1 to 10 carbons atoms, a branched alkyl of 3 to 10 carbons, or a cycloalkyl of 3 to 10 carbons; and all crystalline forms and the pharmaceutically acceptable salts thereof

Abstract: The invention provides a method of improving the viscosity stability upon storage of a fabric softening composition comprising:

Abstract: Compounds of the formula R1 and R2 are independently alkyl of 1 to 6 carbon atoms, allyl, or substituted allyl of 3 to 6 carbon atoms; R3 is hydrogen, alkyl of 1 to 6 carbon atoms, or cycloalkyl of 3 to 10 carbon atoms; and R4 is phenyl or naphthyl substituted with alkyl of 1 to 6 carbon atoms, alkoxy of 1 to 6 carbon atoms or NR5R6; substituted or unsubstituted phenylalkyl wherein the alkyl group contains 1 to 6 carbon atoms; substituted or unsubstituted 5 to 10 membered heteroaryl having 1 to 3 heteroatoms selected from N, S and O; substituted or unsubstituted cycloalkyl of 3 to 10 carbon atoms; or substituted or unsubstituted cycloalkylalkyl of 4 to 10 carbon atoms; provided that phenyl or naphthyl is substituted with NR5R6 when R1 and R2 is alkyl, are useful in the treatment of various disorders associated bone loss by increased transcription and elevation of plasma calcitonin levels.

Abstract: This invention concerns the treatment of smooth muscle spasticity or excess muscle contraction such as urge urinary incontinence with a compound of the formula wherein: R1 and R2 are independently straight chain alkyl of 1 to 6 carbon atoms, branched alkyl of 3 to 6 carbons atoms, or cycloalkyl of 3 to 6 carbons atoms where R1 and R2 may be substituted by F, Cl, Br, I, OH, NH2, cyano, C1-C6 alkoxy, C1-C6alkylthio, COOH or COOC1-C6 alkyl; R3 is an aryl or heteroaryl as defined herein, optionally substituted with 0 to 4 groups selected independently from C1-C6 alkyl, C1-C6 alkoxy, cyano, F, Cl, Br, C1-C6 alkylthio, CO2R1, CONH2, OH, NH2, and NO2; n is 0 or 1; R4 is a straight chain alkyl group of 1 to 10 carbons atoms, a branched alkyl of 3 to 10 carbons, or a cycloalkyl of 3 to 10 carbons; and all crystalline forms and the pharmaceutically acceptable salts thereof.

Abstract: A compound of formula (I) ##STR1## wherein: X=N and Y=CH or X=CH and Y=NR.sub.1 and R.sub.2 are independently, straight chain alkyl of 2 to 12 carbon atoms, branched chain alkyl of 3 to 10 carbon atoms, cycloalkyl of 3 to 10 carbon atoms, aryl of 4 to 10 carbon atoms, 4 to 10 membered heteroaryl or a moiety of the formula (CH.sub.2).sub.m -A wherein m is 1 to 9 and A is cycloalkyl of 3 to 7 carbon atoms; and R.sub.3 is a straight chain alkyl of 1 to 12 carbon atoms, branched chain alkyl of 3 to 10 carbon atoms, aryl of 4 to 10 carbon atoms or 4 to 10 membered heteroaryl for use in the treatment of disorders associated with bone loss by increased transcription and elevation of plasma calcitonin levels.

Abstract: The invention is novel analogs of 9-cis-retinoic acid which are useful for the treatment and prevention of coronary artery disease and to protect against premature atherosclerosis by increasing HDL levels. The invention includes processes for preparing the novel 9-cis-retinoic acid analogs.