Abstract: Disclosed herein, inter alia, are trioxolane compounds and methods of using the same for treatment and detection of diseases.

Abstract: Systems and methods may be provided that may enable an individual to retrieve one or more prescription products (e.g., product refills) from a self-service retrieval location such as a counter, drive-thru, drop box, or kiosk. The individual may identify a medical prescription, and a unique-machine readable code may be generated, wherein the code is associated with the medical prescription and a particular station at an identified retrieval location. The unique machine-readable code may be transmitted to a computing device of the individual, who may scan the code at particular station to retrieve one or more prescription products associated with the medical prescription.

Abstract: Devices, methods, and systems for monitoring and/or assessing compliance with infectious disease guidance for reducing infectious disease transmissions are described herein. The systems may include sensing devices at or within a facility and computing devices to compare data based on outputs from the sensing devices with guidance and/or recommendations for mitigating infectious disease transmission. Various compliance parameters may be identified as being relevant to the guidelines and measurable with outputs from the sensing devices. Various compliance parameters may be identified as being relevant to the guidelines, but not measurable with outputs from the sensing devices. The compliance parameters may be individually scored or scored in groups, including the compliance parameters not measureable with outputs from the sensing devices, and a score relative to a facility or group of facilities may be provided. The scores may be presented to via a dashboard.

Abstract: A configurable workstation includes a support frame defining a workspace for performing a scientific procedure, multiple modules that are configured to be selectively installed to the support frame for customizing a functional profile of the configurable workstation, and a server computing device hosting an application that provides a user interface for controlling operations of the configurable workstation.

Abstract: Deception-based techniques for responding to security attacks are described herein. The techniques include transitioning a security attack to a monitored computing device posing as a computing device impacted by the security attack and enabling the adversary to obtain deceptive information from the monitored computing device. Also, the adversary may obtain a document configured to report identifying information of an entity opening the document, thereby identifying the adversary associated with the attack. Further, the techniques include determining that a domain specified in a domain name request is associated with malicious activity and responding to the request with a network address of a monitored computing device to cause the requesting process to communicate with the monitored computing device in place of an adversary server. Additionally, a service may monitor dormant domains names associated with malicious activity and, in response to a change, respond with an alert or a configuration update.

Abstract: A coffee making device has a body with a drip tray and a removable water tank that supplies water to a heat system of the device. The water tank is internal to the device and removable by a user. The body has a fluid refill opening that leads to the tank. The tank includes an overflow channel or conduit that dispenses into the drip tray.

Abstract: A surgical extractor that includes a first arm and a second arm, a linkage assembly connected to the first and second arms, and a driven shaft operatively engaged with the linkage assembly for moving the linkage assembly between first and second positions. The surgical extractor further includes a tensioning shaft engageable with the driven shaft for moving the driven shaft relative to the linkage assembly.

Abstract: A surgical extractor including first and second arms connected to first and second implant-engageable jaws. The first and second arms are connected by first and third links to a stationary screw jack nut and by second and fourth links to a moveable screw jack nut. A driven shaft is rotatably received in the stationary screw jack nut and threadedly received in the moveable screw jack nut, and a drive shaft rotatably drives the driven shaft. Rotation of the drive shaft in a first direction separates the first and second arms and jaws in order to receive an implant. Rotation of the drive shaft in a second direction closes the first and second arms and jaws in order to clamp an implant. A handle assembly engages the drive shaft in order to drive the drive shaft and disengages from the drive shaft to exert a removal force on an implant.

Abstract: Portable electronic devices are provided. Each device may be formed from two parts. A first part may be provided with components such as a display, a touch screen, a cover glass, and a frame. A second part may be provided with a plastic housing, circuit boards containing electrical components, and a bezel. Engagement members may be connected to the first and second parts. The engagement members may be formed from metal clips with holes and springs with flexible spring prongs that mate with the holes in the clips. The metal clips may be welded to frame struts on the frame and the springs may be welded to the bezel. During assembly, the first part may be rotated into place within the second part. Retention clips attached to the frame may be used to secure the two parts together. Assembly instructions and associated connector numbers may be provided within the devices.

Abstract: A system and method that enables the ongoing communication, tracking, and management review of feedback among a population of workers and their management.

Abstract: Embodiments include an end effector including an anvil that includes a first end, a second end, and an anvil face positionable on the first side of an anatomical structure, a cartridge operably configured to house a plurality of staples, the cartridge comprising a first end, a second end, and a cartridge face positionable on the second side of the anatomical structure. The end effector includes a blade assembly comprising a blade, a beam, and a nut, the blade comprising a first side and a second side joined at a cutting edge. The end effector includes first and second electrodes coupled to the first side of the blade and an electrosurgical power generating source in electrical communication with the first and second electrodes.

Abstract: Dynamic range aware conversion of sensor readings is described. A system includes one or more sensors to sense conditions of a component and output sensor readings and a system manager. The system manager is configured to convert the sensor readings into condition measurements by converting the sensor readings into the condition measurements using a first transformation while operating in a first conversion mode or converting the sensor readings into the condition measurements using a second transformation while operating in a second conversion mode. The system manager then adjusts operation of the component based on the condition measurements.

Abstract: We describe a power converter cooling arrangement in which a base has a top plate of a thermally conductive material, and a bottom plate and side walls define a chamber. An inlet and outlet are in fluid communication with the chamber, and the chamber is flooded with a cooling fluid that flows between the inlet and outlet. A PCB of a power converter is mounted to, and thermally coupled with, the top plate, where the PCB receives a plurality of power modules (that are used in the power conversion). The base comprises a plurality of fluid channels for flowing cooling fluid therethrough. Each of the fluid channels is arranged to coincide with a location of one or more components mounted to the PCB.

Abstract: The disclosed computer-implemented method may include identifying and notifying requestors that may be candidates for a particular autonomous vehicle in order to find those candidates that may be willing or able to relax their travel constraints to match the autonomous vehicle. A request flow may involve surfacing the potential option of matching to an autonomous vehicle before setting a specific destination. For example, the request flow may involve determining that an autonomous vehicle is sufficiently near an in-session potential requestor. Before the potential requestor enters a specific destination, the request flow may present the possibility of the potential requestor being matched with the autonomous vehicle. In some examples, the request flow may then provide available drop-off locations that are compatible with the autonomous vehicle for selection by the potential requestor. Various other methods, systems, and computer-readable media are also disclosed.

Abstract: Caps for sealing assemblies for sealing glass containers and maintaining container closure integrity at ?80° C. or less are disclosed. The caps include a cap skirt having an annular body and a crimp region. The crimp region is a crimpable metal. The annular body of the cap skirt has a coefficient of thermal expansion (CTE) greater than a CTE of a metal consisting of aluminum, a stiffness greater than or equal to 2 times a stiffness of the crimp region, or both. The greater CTE, stiffness, or both of the cap skirt increase the seal pressure and contact area between the stopper and glass container when cooled to ?80° C. or less. The caps enable the sealing assemblies to maintain a helium leakage rate of the sealed glass container of less than or equal to 1.4×10?6 cm3/s at ?80° C. or less.

Abstract: The present document relates to methods and apparatus for rendering input audio for playback in a playback environment. The input audio includes at least one audio object and associated metadata, and the associated metadata indicates at least a location of the audio object. A method for rendering input audio including divergence metadata for playback in a playback environment comprises creating two additional audio objects associated with the audio object such that respective locations of the two additional audio objects are evenly spaced from the location of the audio object, on opposite sides of the location of the audio object when seen from an intended listener's position in the playback environment, determining respective weight factors for application to the audio object and the two additional audio objects, and rendering the audio object and the two additional audio objects to one or more speaker feeds in accordance with the determined weight factors.

Abstract: Methods for a reusable space vehicle to land at substantially the same location as its launching site. The vehicle traveling in a particular orbit, which is a repeating ground track orbit, allows for launching and landing at the same location once per day. The repeating ground track orbits that allow for launching and landing at the same location once per day overfly the launch and landing site once per day. Launching and landing at the same site provides a number of direct advantages. For example, the just-landed vehicle may be transported a relatively short distance to the launch site, reconditioned relatively quickly, and be ready for a quick turn-around launch.

Abstract: A system and model by which to manage edits to localized versions of base-language electronic content. The model determines the likelihood of whether a modification made to a document is substantive and should be propagated back to the base electronic content and assists users in identifying these edits. The proposed method can significantly improve workflow efficiency and allow users to feel more comfortable in the development and use of their electronic content across multiple authoring platforms.

Abstract: Systems and methods of the present disclosure are directed toward digital signal processing using machine-learned differentiable digital signal processors. For example, embodiments of the present disclosure may include differentiable digital signal processors within the training loop of a machine-learned model (e.g., for gradient-based training). Advantageously, systems and methods of the present disclosure provide high quality signal processing using smaller models than prior systems, thereby reducing energy costs (e.g., storage and/or processing costs) associated with performing digital signal processing.