Abstract: A sealed pharmaceutical container includes a shoulder, a neck extending from the shoulder, and a flange extending from the neck. The flange includes an inclined sealing surface defining an opening in the sealed pharmaceutical container. The sealed pharmaceutical container also includes a sealing assembly including a stopper extending over the sealing surface of the flange and a cap securing the stopper to the flange. The stopper has a glass transition temperature (Tg) that is greater than or equal to ?70° C. and less than or equal to ?45° C. The sealing assembly maintains a helium leakage rate of the sealed pharmaceutical container of less than or equal to 1.4×10?6 cm3/s as the sealed pharmaceutical container is cooled to a temperature of less than or equal to ?45° C.

Abstract: A system and method are provided for simulating circuits that transmit bidirectional signals between some ports using simulators designed originally for electrical circuits and systems, that eliminate the need for different port interfaces. The system and method can be applied to simulate photonic circuits either standalone or integrated with electrical circuits and systems. In one method implemented by the system potential and flow representations, available for example in Verilog-A simulators, are used to create bidirectional signals on a single bus line to transmit optical signals. In another method implemented by the system, the system auto-configures each optical port type as left or right at runtime or during a pre-simulation initialization to allow for bidirectional signals with a single port interface.

Abstract: Disclosed herein are glass pharmaceutical vials having sidewalls of reduced thickness. In embodiments, the glass pharmaceutical vial may include a glass body comprising a sidewall enclosing an interior volume. An outer diameter D of the glass body is equal to a diameter d1 of a glass vial of size X as defined by ISO 8362-1, wherein X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1. However, the sidewall of the glass pharmaceutical vial comprises an average wall thickness Ti that is less than or equal to 0.85*s1, wherein s1 is a wall thickness of the glass vial of size X as defined by ISO 8362-1 and X is one of 2R, 3R, 4R, 6R, 8R, 10R, 15R, 20R, 25R, 30R, 50R, and 100R as defined by ISO 8362-1.

Abstract: A sealed pharmaceutical container comprises a flange comprising an underside surface, an outer surface extending from the underside surface, the outer surface defining an outer radius ro of the flange; and an upper surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The upper surface comprises a sealing region extending between the opening and the outer surface and comprising a radius rsr that is less than ro. The sealed pharmaceutical container also comprises a sealing assembly comprising sealing portion in contact with the upper surface at a lower surface of the sealing portion and a cap compressing the stopper against the upper surface. After compression, the sealing portion of the stopper comprises a compressed radius rsc that is less than rsr adjacent the upper surface.

Abstract: A media playback queue defining the upcoming playback sequence of media data items may be continually generated using an automatic software function or manual user selections. The playback queue may be edited to modify or re-arrange the upcoming playback sequence. Automatic addition of media data items may be controlled by defining a non-predetermined set of media data items comprising a subset of a media library, such as a combination of filesystem directories or specifically selected metadata tags. The playback queue may be configured to maintain a minimum number of queued media data items, to provide a mechanism of anticipating upcoming media data items intended for playback, and to allow for pre-emptive modification of the playback queue sequence by editing the anticipated playback queue. Th invention provides a controllable method of random shuffled automatic media library playback by providing a novel opportunity to remove undesired items from the playback queue.

Abstract: Example methods, apparatus, and articles of manufacture to estimate waiting times of prescriptions are disclosed herein. An example computer-implemented method, executed by a processor, to estimate a waiting time of a prescription for a medication includes training a machine learning model using, for each of a plurality of previously filled prescriptions, a set of characteristics of the previously filled prescription, and a fill time for the previously filled prescription, receiving a prescription for a medication for a patient, receiving a request for an estimated waiting time for filling the prescription medication for the patient, identifying a set of characteristics of the prescription medication for the patient, applying the set of characteristics of the prescription medication to the machine learning model to determine the estimated waiting time for filling the prescription medication for the patient, and providing an indication of the estimated waiting time for display on a client device.

Abstract: A glass container includes a glass body comprising an external surface, an internal surface opposite the external surface, a thickness T extending between the external surface and the internal surface, and an external surface layer extending from the external surface into the thickness of the glass body, wherein the external surface layer has a porosity greater than a porosity of a remainder of the glass body extending from the external surface layer to the internal surface.

Abstract: A shim or badge is affixed to a golf club body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening and extend into the toe portion in the golf club body, the golf club head can provide increased stiffness in the topline, while lowering CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.

Abstract: A system and method that enables the ongoing communication, tracking, and management review of feedback among a population of workers and their management.

Abstract: A shim or badge is affixed to a golf cub body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening and extend into the toe portion of the golf club body, the golf club head can provide increased stiffness in the topline, while lowering CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.

Abstract: Apparatus and method for adaptively adjusting amplifier gain based on detected distance to a target in a light detection and ranging (LiDAR) system. In some embodiments, the amplifier amplifies detected pulses obtained from a photodetector, and the gain is adjusted from among at least two selectable gain modes responsive to a measured time of flight (ToF) for the pulses. A first range of gain levels can be used for targets that are within a first maximum distance range, and a second range of gain levels can be used for targets that are beyond the first maximum distance range. Each mode can extend from a minimum to a maximum value along a selected linear slope. A gain adjustment circuit can use a Gilbert Cell or a multiplier and fully differential amplifier arrangement.

Abstract: A light detection and ranging system can have a light source coupled to a polygon reflector having a plurality of facets. A controller can be connected to the light source and directed to generate and execute a calibration strategy that alters an orientation of the light source in response to identification of a position of at least one facet of the plurality of facets.

Abstract: Disclosed herein, inter alia, are trioxolane compounds and methods of using the same for treatment and detection of diseases.

Abstract: A shim or badge is affixed to a golf cub body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening in the golf club body, the golf club head can provide increased stiffness in the topline, while maintaining a low CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.

Abstract: A system and method that enables the ongoing communication, tracking, and management review of feedback among a population of workers and their management.

Abstract: The disclosure provides compositions and methods for identifying and/or quantifying a binding member in a sample.

Abstract: A sealed pharmaceutical container comprises a shoulder, a neck extending from the shoulder, and a flange extending from the neck. The flange comprises an outer surface extending from the underside surface and a contact surface extending between the outer surface and an inner surface defining an opening in the sealed pharmaceutical container. The contact surface comprises an outer peripheral edge disposed proximate to the outer surface of the flange. The sealed pharmaceutical container comprises a sealing assembly comprising a stopper extending over the contact surface of the flange and covering the opening, and a cap securing the stopper to the flange. The stopper comprises a sealing surface that is secured in contact with the contact surface of the flange to form a seal between the flange and the stopper. An outer peripheral edge of the sealing surface is disposed at or radially inward of the outer peripheral edge.

Abstract: A damper is provided within the cavity of a golf club head and spans substantially the full length of the striking face from heel-to-toe of the golf club head. One or more cutouts and/or other relief is provided in the damper to reduce the surface area of the damper that contacts thep rear surface of the striking face. By reducing the surface area that the damper contacts the rear surface of the striking face, the full length damper improves the sound and feel of the golf club head at impact and only minimally reduces performance of the golf club head. For example, the one or more cutouts and/or other relief maintains face flexibility, characteristic time (CT) and coefficient of restitution (COR) of the striking face.

Abstract: Glass compositions include titania (TiO2), lanthanum oxide (La2O3), boron oxide (B2O3), silica (SiO2) as essential components and may optionally include zirconia (ZrO2), niobia (Nb2O5), calcium oxide (CaO), barium oxide (BaO), yttria (Y2O3), zinc oxide (ZnO), gadolinium oxide (Gd2O3), gallia (Ga2O3), tungsten oxide (WO3) and other components. The glasses may be characterized by high refractive index at 587.56 nm at comparably low density at room temperature.

Abstract: A shim or badge is affixed to a golf cub body to produce a cap-back iron, giving the appearance of a hollow-body iron. In this way, the golf club can be manufactured with the performance benefits of a game improvement iron, while providing the appearance of a blade, player's iron, and/or a hollow-body iron. For example, by using a lightweight and rigid shim or badge to close a cavity opening and extend into the toe portion in the golf club body, the golf club head can provide increased stiffness in the topline, while lowering CG. Various shim or badge arrangements and materials can be used, and a filler material and/or damper can be included within the cavity to improve sound and feel, while minimizing loss in COR.