Abstract: The invention relates to a vaccine comprising live attenuated recombinant alphavirus comprising mutated capsid protein. The invention also relates to a method of preventing a subject from contracting an alphaviral infection that would otherwise produce clinical signs of disease. In an embodiment the mutated capsid protein is Chikungunya virus (CHIKV) capsid protein having a mutated nucleolar localisation signal/sequence (NoLS), preferably the mutant NLS 101/95.

Abstract: An oscillation system comprises an oscillation circuitry configured to cause at least one motor of a first set of motors to provide an oscillation of a user-input device in at least one axis of the user-input device. The oscillation may be triggered in response to an input from at least one sensor, the user-input device for operating an aircraft control system of an aircraft. The oscillation circuitry is configured to operate independently from a resistive force circuitry. The resistive force circuitry is to provide a resistive force to the user-input device, using the at least one motor of the first set of motors.

Abstract: Aircraft control systems to enable shared input controls. A single inceptor may provide outputs to control both land-based aircraft controls and air-based aircraft controls to reduce the number of inceptors required. In an example a side-stick provides control of both pitch and aircraft nose-wheel steering. Active inceptor technology may be utilised to provide feedback to the operator on the control system state.

Abstract: An aircraft (101) is provided with a single centrally located inceptor (110) for controlling pitch and roll of the aircraft. The inceptor (110) is provided with a double grip (11, 112) so that it may be comfortably operated by either a pilot or a co-pilot. A central location for the inceptor ensures that its motion and position is visible to both pilot and co-pilot. Not only is this a benefit from a safety point of view but also during pilot training. Alternatively, two inceptors (411, 412) are provided in the centre console (406) adjacent to one another for operation respectively by the pilot and co-pilot and may be mechanically linked. Optionally, the aircraft may be provided with outboard throttle quadrants (117, 118) for operation respectively by the co-pilot and pilot. The outboard throttle quadrants may be mechanically linked together.

Abstract: A gear train includes a first gear having teeth meshed with teeth of a second gear. Each tooth of the first gear includes a coast side and a drive side opposed to the coast side. The drive side has a pressure angle that is greater than that of the coast side. The gear train can be part of a powertrain system for a rotorcraft, and can replace a traditional gear train in a retrofit or new build. The first gear is a planet gear and the second gear is a ring gear wherein the planet gear and ring gear are in a planetary gear train configuration.

Abstract: A device to extract digital and unintended analog signals from a data bus with a non-contact common mode probe and a differential mode probe, each with a low noise amplifier. The analog and digital signals can be monitored contemporaneously.

Abstract: The invention relates to a vaccine comprising live attenuated recombinant alphavirus comprising mutated capsid protein. The invention also relates to a method of preventing a subject from contracting an alphaviral infection that would otherwise produce clinical signs of disease. In an embodiment the mutated capsid protein is Chikungunya virus (CHIKV) capsid protein having a mutated nucleolar localisation signal/sequence (NoLS), preferably the mutant NLS 101/95.

Abstract: A device to extract digital and unintended analog signals from a data bus with a non-contact common mode probe and a differential mode probe, each with a low noise amplifier. The analog and digital signals can be monitored contemporaneously.

Abstract: A method of task-based cache isolation includes: storing, in association with a cache controller, (i) a plurality of mask descriptors representing respective portions of a cache memory, and (ii) for each mask descriptor, a mask identifier; receiving, at the cache controller, a memory transaction request containing a memory address and an active one of the mask identifiers; retrieving, at the cache controller, an active one of the mask descriptors corresponding to the active mask identifier; generating, based on the memory address and the active mask descriptor, an index identifier corresponding to a cache element within the portion of the cache memory represented by the active mask descriptor; and applying the memory transaction to the cache memory at the index identifier.

Abstract: A water remediation and treatment device that includes a process channel having fluid inlet and a fluid outlet; at least one tube unit in fluid communication with the process channel, the tube unit defining an interior chamber defining an interior fluid flow path, at least one anode and at least one cathode contained in the interior chamber and positioned in the interior fluid flow path; and at least one device configured to remove material accumulated on the surface of the cathode and/or the electrode during water treatment.

Abstract: An anti-segregation mixer for a bed of material, the anti-segregation mixer comprising: an elongate and substantially cylindrical shell having an inner surface; and a plurality of independent lifting means provided within the shell, wherein the plurality of lifting means each comprise a vane with a leading end and a trailing end, and are arranged with respect to the cylindrical shell such that the vane is spaced apart from the inner surface and the entire lifting means may pass through the bed of material.

Abstract: Aircraft control systems to enable shared input controls. A single inceptor may provide outputs to control both land-based aircraft controls and air-based aircraft controls to reduce the number of inceptors required. In an example a side-stick provides control of both pitch and aircraft nose-wheel steering. Active inceptor technology may be utilised to provide feedback to the operator on the control system state.

Abstract: An interlocking modular animal training pad tray configured to interlock with one or more adjacent interlocking modular animal training pad trays while preventing leaking between the adjacent trays. The interlocking modular animal training pad tray having a modular body with four rigid sides forming a tray configured to hold an animal training pad. Each side of the four rigid sides including at least one fastening element.

Abstract: An interlocking modular animal training pad tray configured to interlock with one or more adjacent interlocking modular animal training pad trays while preventing leaking between the adjacent trays. The interlocking modular animal training pad tray having a modular body with four rigid sides forming a tray configured to hold an animal training pad. Each side of the four rigid sides including at least one fastening element.

Abstract: A surgical navigation system and method for identifying positions on a patient, including a processor, and a tracking system for tracking a pointer tool. The processor is programmed to initialize a surface trace acquisition, continuously record the positions of the pointer tool during the surface, conduct trace acquisition, combine the positions recorded during the surface trace acquisition into a surface trace, receive a patient image of the patient, extract a surface from the patient image, compute a registration transform between the surface traces and the surface for patient registration, segment the patient image into a regions where each region contains an anatomical landmark, determine a spatial distribution of surface traces among the regions; determine whether the spatial distribution in relation to each region minimizes deviance below a threshold, and if the determination is exceeding the threshold, provide information relating to such region.

Abstract: Methods and apparatus to identify additively manufactured parts are disclosed. An example apparatus includes a body, formed of layers layered substantially parallel to a base layer, composed of a first material having a first density, a first indicium embedded internally in the body as a void, and a second indicium on an external surface of the body, the second indicium aligning with the first indicium.

Abstract: There is provided a dispersion apparatus for use with a solid fuel burner. The dispersion apparatus comprises a passage through which particulate material may flow toward an outlet region for dispersal therefrom, the flow being at least in part rotational about the longitudinal axis of the passage. The dispersion apparatus also comprises a downstream guide means arranged within the passage at or near the outlet region, the downstream guide means configured to at least reduce the rotational motion so that the flow progresses toward the outlet region in a substantially uniform manner in a direction aligned with a longitudinal axis of the passage.

Abstract: A surgical navigation system and method for identifying positions on a patient, including a processor, and a tracking system for tracking a pointer tool. The processor is programmed to initialize a surface trace acquisition, continuously record the positions of the pointer tool during the surface, conduct trace acquisition, combine the positions recorded during the surface trace acquisition into a surface trace, receive a patient image of the patient, extract a surface from the patient image, compute a registration transform between the surface traces and the surface for patient registration, segment the patient image into a regions where each region contains an anatomical landmark, determine a spatial distribution of surface traces among the regions; determine whether the spatial distribution in relation to each region minimizes deviance below a threshold, and if the determination is exceeding the threshold, provide information relating to such region.

Abstract: Methods and apparatus to identify additively manufactured parts are disclosed. An example method of manufacturing includes layering a first set of layers of a first material via an additive manufacturing technique, the first material having a first density and layering a second set of layers of the first material via the additive manufacturing technique, the second set of layers to form a void embedded internally in the part, the void forming an indicium.

Abstract: An active inceptor apparatus and method for operating a machine. The apparatus comprises a stick member having a grip portion, the stick member being pivotably mounted relative to a housing. It further comprises a position sensor responsive to, and for generating signals indicative of, stick member position. A force sensor is provided on the stick member responsive to, and for generating signals indicative of, force applied to the stick by a user. The apparatus also includes a control unit operable to receive the position and force signals from the position and force sensors respectively. The control unit is operable to process the signals according to a predetermined relationship to determine a value FD indicative of force applied to the stick member relative to displacement of the stick member. The control unit is also operable to generate machine control signals as a function of position signals and force signals in dependence upon the value FD, for communication to the machine.