Abstract: Techniques are disclosed for measuring a concentration of an analyte in a subject based on reflectance spectra obtained from the subject. The spectra are obtained while and/or before and/or after photoreactions are induced in the subject, where the photoreactions change the reflectivity of the subject. The rate of change of the reflectivity is correlated with the concentration of the analyte.

Abstract: Apparatuses, systems, and techniques to adapt instructions in a SIMT architecture for execution on serial execution units. In at least one embodiment, a set of one or more threads is selected from a group of active threads associated with an instruction and the instruction is executed for the set of one or more threads on a serial execution unit.

Abstract: A method for treating a subject in need thereof having a bone or blood cancer, or a cancer that metastasizes to bone that includes administering to the subject an effective amount of hydroxyureamethyl acylfulvene.

Abstract: An example method for provisioning volumes in a distributed storage system comprises: receiving a volume provision request to allocate data storage space for a storage volume on a storage node cluster comprising a plurality of storage nodes; determining, in response to the volume provision request, locations of replicas of other storage volumes on the plurality of storage nodes; determining, based on the locations of the replicas of the other storage volumes, a placement of replicas of the storage volume on a set of storage nodes of the plurality of storage nodes that minimizes a number of failed storage volumes in an event of a failure of the set of storage nodes; and provisioning, based on the determining the placement, the storage volume on the set of storage nodes.

Abstract: The methods include treating atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene. Some embodiments relate to treatment of atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene to a population or subject expressing SMARCB1.

Abstract: An illustrative method includes detecting a request to perform a cluster-wide snapshot of a cluster comprising one or more nodes on which one or more containerized applications are deployed, the snapshot corresponding to a point in time; preparing, based on the request, objects within the cluster for the snapshot; and generating, in response to the preparing, the cluster-wide snapshot of the cluster.

Abstract: The methods include treating atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene. Some embodiments relate to treatment of atypical teratoid/rhabdoid tumor by administration of HydroxyUreaMethyl Acylfulvene to a population or subject expressing SMARCB1.

Abstract: This application relates to markers for use in the determination of the sensitivity of a cancer patient to an anti-cancer agent (e.g., illudins/illudin analogs) to be administered thereto, which markers can determine whether or not the cancer of the patient has a therapeutic response to the anti-cancer agent, and to application of the markers.

Abstract: A controller for a storage system manages distribution of snapshots for one or more replicas of a dataset. In certain embodiments, the controller may perform steps including: determining, within a container system, a set of storage resources, where a volume is replicated on each storage resource of the set of storage resources, and wherein the set of storage resources comprises a first number of storage resources associated with a replication factor for the volume; determining, based on a replication policy and in response to an indication to generate a snapshot of the volume, a subset of storage resources, where the subset of storage resources comprises a second number of storage resources that is less than the replication factor; and generating, in accordance with the replication policy, a snapshot of the volume on each storage resource of the subset of storage resources.

Abstract: A container storage system that provides storage services to a container system provides data resiliency using storage pools based on: detecting an interruption to storage services associated with a first storage pool that includes a first plurality of storage resources on which a first set of replicas of a dataset is distributed; selecting, in response to the interruption, a second storage pool that includes a second plurality of storage resources; and generating, based on one or more replicas within the first set of replicas, a second set of replicas of the dataset distributed among the second plurality of storage resources in the second storage pool.

Abstract: A method for treating cancer in a patient in which a sample of the tumor or cancer is obtained from the patient and screened for responsiveness to 2,2?-dithio-bis-ethane sulfonate analogs. The sample is treated with 2,2?-dithio-bis-ethane sulfonate analogs to determine whether one or more of a plurality of biomarkers will be expressed therein.

Abstract: Methods for treating brain tumor cancer by administration hydroxyureamethyl-acylfulvene. Some embodiments relate to treatment of glioblastoma by administration of hydroxyureamethyl-acylfulvene. Method also includes characterizing the subtype and genetics of the markers.

Abstract: Methods for treating pancreatic cancer by administration hydroxyureamethyl acylfulvene. Some embodiments relate to treatment of pancreatic cancer by administration of hydroxyureamethyl acylfulvene.

Abstract: Compounds, pharmaceutical compositions, and methods are provided herein that may be used to treat cancer, infectious disease, and other conditions associated with ectonucleotide pyrophosphatase pyrophosphatase-phosphodiesterase (ENPP1) dysfunction.

Abstract: A method includes receiving a plurality of data processing requests and generating a primary processing stack indicating a queue for processing the first data. The primary processing stack comprises a plurality of layers. Each layer comprises a plurality of slices, wherein each slice represents a portion of the first data of at least one data processing request. The plurality of slices are arranged within each layer based at least on the priority indicator corresponding to the first data that each slice represents. The method further includes receiving resource information about a plurality of servers, assigning each slice of the primary processing stack to one of the servers, and sending processing instructions comprising an identification of each slice of the primary processing stack assigned to the respective server.

Abstract: The present disclosure relates to polymers comprising conjugates of cyclodextrin or derivatives thereof and a linker moiety, methods of preparing the same and their application in the removal of lipids such as cholesterol from cells in treating lipid storage disorders. The present polymers exhibit improved properties including but not limiting to improved biocompatibility, improved retention time, prolonged duration of action in cells, and increased efficacy in removal of cholesterol from cells in treating lipid storage disorders.

Abstract: Presented herein are methods, non-transitory computer readable media, and devices for integrating a hybrid model of fine-grained locking and data-partitioning wherein fine-grained locking is added to existing systems that are based on hierarchical data-partitioning in order in increase parallelism with minimal code re-write.

Abstract: A method of treating a female patient suffering from non-small cell lung cancer includes the step of administering to the patient in need thereof a composition of 2,2?-dithio-bis-ethane sulfonate, or a pharmaceutically-acceptable salt thereof. The method can include other primary line therapies.

Abstract: Presented herein are methods, non-transitory computer readable media, and devices for integrating a hybrid model of fine-grained locking and data-partitioning wherein fine-grained locking is added to existing systems that are based on hierarchical data-partitioning in order in increase parallelism with minimal code re-write.

Abstract: Presented herein are methods, non-transitory computer readable media, and devices for optimizing thread assignment to schedulers, avoid starvation of individual data partitions, and maximize parallelism in the presence of hierarchical data partitioning are disclosed, which include: partitioning, by a network storage server, a scheduler servicing a data partitioned system into a plurality of autonomous schedulers; determining what fraction of thread resources in the data partitioned system at least one of the plurality of autonomous schedulers is to receive; and determining, with minimal synchronization, when it is time to allow the at least one of the plurality of autonomous schedulers servicing a coarse hierarchy to run.