Abstract: Presented herein are methods, non-transitory computer readable media, and devices for efficiently administering locks for shared resources, such as data blocks, stored on a storage system. Methods for stamping a plurality of computer data objects are disclosed which include: accessing at least one of the plurality of computer data objects by a first data thread; assigning, by the first data thread, a stamp to the at least one of the plurality of computer data objects, to signify the at least one of the plurality of computer data objects is associated with the first data thread; preventing subsequent access by a second data thread to the stamped at least one of the plurality of computer data objects; and determining the stamp is no longer active, upon an event, effectively releasing the at least one of the plurality of computer data objects.

Abstract: The invention relates to nucleic acid complexes, methods of preparation thereof, and uses thereof for delivering a nucleic acid into a cell.

Abstract: A configuration mapping system and method increase the effectiveness of mapping of information from an established product line to a new product offering. In at least one embodiment, the configuration mapping system herein uses configuration mapping rules to map individual product features and entire configurations from established products to a new product offering. The configuration mapping system also provides a way to appropriately map, for example, demand and sales information for the purpose of demand estimation and sales prediction. Conventionally, mapping can be ineffective because the configuration mapping rules usually focus on one part of the product at a time, and, if applied in isolation, the impact on other parts is missed. The systems and method herein provide a way to integrate configuration mapping rules across feature parts, time periods, and product lines into a unified, holistic view, allowing for new insights.

Abstract: Various embodiments of the present invention are directed to polyrotaxanes comprising a poloxamer core and at least one cyclodextrin and methods for treating Niemann-Pick type C (NPC) and imaging (e.g., MRI) using the polyrotaxanes various embodiments of the present invention.

Abstract: The invention relates to nucleic acid complexes, methods of preparation thereof, and uses thereof for delivering a nucleic acid into a cell.

Abstract: The invention relates to nucleic acid complexes, methods of preparation thereof, and uses thereof for delivering a nucleic acid into a cell.

Abstract: A server that caches data in a storage system includes a data access manager that accesses data with a physical location identifier instead of a logical block reference identifier used by a filesystem that manages the cached data. The data access manager provisions a buffer from a pool of buffers maintained by the filesystem, and associates the provisioned buffer with a cache location separate from a buffer cache maintained by the filesystem. The data access manager issues a read for the data with the physical location identifier to obtain the data, and stores the data in the cache location separate from the buffer cache in the provisioned buffer. The data access manager performs a validity check on the obtained data and discards the obtained data when the validity check fails. The data access manager provides access to the buffer to a requesting program.

Abstract: The invention relates to nucleic acid complexes, methods of preparation thereof, and uses thereof for delivering a nucleic acid into a cell.

Abstract: A configuration mapping system and method increase the effectiveness of mapping of information from an established product line to a new product offering. In at least one embodiment, the configuration mapping system herein uses configuration mapping rules to map individual product features and entire configurations from established products to a new product offering. The configuration mapping system also provides a way to appropriately map, for example, demand and sales information for the purpose of demand estimation and sales prediction. Conventionally, mapping can be ineffective because the configuration mapping rules usually focus on one part of the product at a time, and, if applied in isolation, the impact on other parts is missed. The systems and method herein provide a way to integrate configuration mapping rules across feature parts, time periods, and product lines into a unified, holistic view, allowing for new insights.

Abstract: A method for designing a multi-threaded processing operation that includes, e.g., multimedia encoding/decoding, uses an architecture having multiple processors and optional hardware accelerators. The method includes the steps of: identifying a desired chronological sequence of processing stages for processing input data including identifying interdependencies of said processing stages; allotting each said processing sage to a processor; staggering the processing to accommodate the interdependencies; selecting a processing operation based on said allotting to arrive at a subset of possible pipelines that offer low average processing time; and, choosing one design pipeline from said subset to result in overall timing reduction to complete said processing operation. The invention provides a multi-threaded processing pipeline that is applicable in a System-on-Chip (SoC) using a DSP and shared resources such as DMA controller and on-chip memory, for increasing the throughput.

Abstract: A method for designing a multi-threaded processing operation that includes, e.g., multimedia encoding/decoding, uses an architecture having multiple processors and optional hardware accelerators. The method includes the steps of: identifying a desired chronological sequence of processing stages for processing input data including identifying interdependencies of said processing stages; allotting each said processing sage to a processor; staggering the processing to accommodate the interdependencies; selecting a processing operation based on said allotting to arrive at a subset of possible pipelines that offer low average processing time; and, choosing one design pipeline from said subset to result in overall timing reduction to complete said processing operation. The invention provides a multi-threaded processing pipeline that is applicable in a System-on-Chip (SoC) using a DSP and shared resources such as DMA controller and on-chip memory, for increasing the throughput.