Patents by Inventor Agnes Tempez

Agnes Tempez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gold implantation/deposition of biological samples for laser desorption two and three dimensional depth profiling of biological tissues
    Publication number: 20060138317
    Abstract: The present invention enhances the laser desorption of biological molecular ions from surfaces by creating a surface localized MALDI particle matrix by ion implantation of low energy ionized clusters (gold, aluminum, etc.) or chemically derivatized clusters into the near surface region of the sample. MALDI analysis of the intact biomolecules on the surface or within a narrow subsurface region defined by the implantation range of the ions can then be performed by laser desorption into a mass spectrometer or, in a preferred embodiment, into a combined ion mobility orthogonal time of flight mass spectrometer.
    Type: Application
    Filed: September 21, 2005
    Publication date: June 29, 2006
    Inventors: J. Schultz, Michael Ugarov, Thomas Egan, Agnes Tempez, Yvon Le bayec, Serge Negra
  • Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions
    Patent number: 6992284
    Abstract: Improved ion focusing for an ion mobility drift cell allows for improved throughput for subsequent detection such as mass detection. Improved focusing is realized by the use of alternating regions of high and low electric fields in the ion mobility drift cell.
    Type: Grant
    Filed: October 20, 2004
    Date of Patent: January 31, 2006
    Assignee: Ionwerks, Inc.
    Inventors: J. Albert Schultz, Valeri Raznikov, Thomas F. Egan, Michael V. Ugarov, Agnes Tempez
  • Gold implantation/deposition of biological samples for laser desorption three dimensional depth profiling of tissues
    Patent number: 6989528
    Abstract: The present invention enhances the laser desorption of biological molecular ions from surfaces by creating a surface localized MALDI particle matrix by ion implantation of low energy ionized clusters (gold, aluminum, etc.) or chemically derivatized clusters into the near surface region of the sample. MALDI analysis of the intact biomolecules on the surface or within a narrow subsurface region defined by the implantation range of the ions can then be performed by laser desorption into a mass spectrometer or, in a preferred embodiment, into a combined ion mobility orthogonal time of flight mass spectrometer.
    Type: Grant
    Filed: June 4, 2004
    Date of Patent: January 24, 2006
    Assignee: Ionwerks, Inc.
    Inventors: J. Albert Schultz, Michael V. Ugarov, Thomas F. Egan, Agnes Tempez, Yvon Le Beyec, Serge Della-Negra
  • Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions
    Publication number: 20050109931
    Abstract: Improved ion focusing for an ion mobility drift cell allows for improved throughput for subsequent detection such as mass detection. Improved focusing is realized by the use of alternating regions of high and low electric fields in the ion mobility drift cell.
    Type: Application
    Filed: October 20, 2004
    Publication date: May 26, 2005
    Inventors: J. Schultz, Valeri Raznikov, Thomas Egan, Michael Ugarov, Agnes Tempez
  • Gold implantation/deposition of biological samples for laser desorption three dimensional depth profiling of tissues
    Publication number: 20050035284
    Abstract: The present invention enhances the laser desorption of biological molecular ions from surfaces by creating a surface localized MALDI particle matrix by ion implantation of low energy ionized clusters (gold, aluminum, etc.) or chemically derivatized clusters into the near surface region of the sample. MALDI analysis of the intact biomolecules on the surface or within a narrow subsurface region defined by the implantation range of the ions can then be performed by laser desorption into a mass spectrometer or, in a preferred embodiment, into a combined ion mobility orthogonal time of flight mass spectrometer.
    Type: Application
    Filed: June 4, 2004
    Publication date: February 17, 2005
    Inventors: J. Schultz, Michael Ugarov, Thomas Egan, Agnes Tempez, Yvon Le Bayec, Serge Della-Negra