Patents by Inventor Ajit Kumar Shasany
Ajit Kumar Shasany has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 6979471Abstract: The invention relates to a new use of a non-alkaloid compound that is plant derived glycoside ‘glycyrrhizin’ as a highly potent bio-enhancer of activity and availability of antibiotics and other drugs including anti-infective and anticancer agents. The molecule of invention facilitates the absorption/uptake of antibiotics and other molecules across the cell membrane in plant and animal cells as well as Gram-positive and Gram-negative bacteria and therefore can be used as a drug facilitator or bioenhancer molecule to increase the affectivity of drugs and nutraceutical agents. The compound having no antimicrobial or cytotoxic activity of its own, is a safe candidate to reduce the drug dosage towards circumventing the problem of drug resistance and the other side effects in anti-infective and anti-cancer therapies.Type: GrantFiled: September 5, 2000Date of Patent: December 27, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Sushil Kumar, Jai Shankar Arya, Ajit Kumar Shasany, Monika Singh, Soumya Awasthi, Subhas Chandra Gupta, Mahendra Pandurang Darokar, Laiq Ur Rahman
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Patent number: 6896907Abstract: The invention relates to a novel pharmaceutical composition comprising an effective amount of bio-active fraction from cow urine distillate as a bioavailability facilitator and pharmaceutically acceptable additives selected from anticancer compounds, antibiotics, drugs, therapeutic and nutraceutic agents, ions and similar molecules which are targeted to the living systems.Type: GrantFiled: May 1, 2002Date of Patent: May 24, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Sushil Kumar, Ajit Kumar Shasany, Jai Shankar Arya, Mahendra Pandurang Darokar, Monika Singh, Prachi Sinha, Soumya Awasthi, Subhash Chandra Gupta, Vivek Kumar Gupta, Madan Mohan Gupta, Ram Kishore Verma, Sweta Agarwal, Sunil Balkrishna Mansinghka, Suresh Haribhau Dawle
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Patent number: 6858588Abstract: The present invention relates to a novel nitrile glycoside of Formula I named NIAZIRIDIN and to analogues and derivatives thereof. The present invention also relates to a process for the isolation of a novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues by bioactivity-guided fractionation from the pods of Moringa oleifera. The present invention particularly relates to the bioenhancing activity of the novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues in enhancing bioactivity of commonly used antibiotics such as rifampicin, tetracycline and ampicillin against Gram (+) and (?) bacteria. The biomolecule also enhances the absorption of drugs, vitamins and nutrients through the gastro-intestinal membrane increasing their bio-availability. Therefore niaziridin can be used in combination therapy with drugs and nutrients resulting in reduced drug associated toxicity, reduced cost and duration of chemotherapy.Type: GrantFiled: March 31, 2003Date of Patent: February 22, 2005Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Jai Shanker Arya, Ranganathan Santha Kumar Tiruppadiripuliyur, Dharmendra Saikia, Harpreet Kaur, Monika Singh, Subhash Chandra Gupta, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Santosh Kumar Srivastava, Madan Mohan Gupta, Subash Chandra Verma, Anirban Pal
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Patent number: 6833249Abstract: The present invention relates to a rapid, sensitive, simple, and cost-effective spectrophotometric method of detecting and quantifying mycolic acid in a mycolic acid-fuschin dye complex with absorbance maxima ranging between 490-500 nm in the presence of various test compounds, for screening mycolic acid biosynthesis inhibitors useful as anti-microbial agents and a diagnostic kit thereof comprising basic fuschin dye in the concentration ranging between 0.1-1.0 gm/100 ml, phenol and 95% ethanol in the ratio ranging between 1:4 to 2:1 (v/v), and phenol and distilled water in the ratio ranging between 1:14 to 1:25.Type: GrantFiled: March 22, 2002Date of Patent: December 21, 2004Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Suchi Srivastava, Tiruppadiripuliyur Ranganathan Santha Kumar, Ajit Kumar Shasany
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Patent number: 6831100Abstract: The present invention describes a novel and very quick bacterial system based screening protocol to detect UV protectant molecules and determining their efficacy for the extent of protection against Ultraviolet radiation in biological systems, identifying a new use of the compound menthyl benzoate as efficient UV protectant suitable for providing protection against the harmful effects of ultraviolet radiation and the extent of protection provided by menthyl benzoate.Type: GrantFiled: June 17, 2003Date of Patent: December 14, 2004Assignee: Council of Scientific & Industrial Research Rafi MargInventors: Suman Preet Singh Khanuja, Krishna Kumar Agarwal, Tiruppadiripuliyur Ranganathan Santha Kumar, Atique Ahmad, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Sushil Kumar
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Publication number: 20040198669Abstract: The present invention relates to a novel nitrile glycoside of Formula I named NIAZIRIDIN and to analogues and derivatives thereof. The present invention also relates to a process for the isolation of a novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues by bioactivity-guided fractionation from the pods of Moringa oleifera. The present invention particularly relates to the bioenhancing activity of the novel nitrile glycoside of Formula I below named NIAZIRIDIN and its derivatives and analogues in enhancing bioactivity of commonly used antibiotics such as rifampicin, tetracycline and ampicillin against Gram (+) and (−) bacteria. The biomolecule also enhances the absorption of drugs, vitamins and nutrients through the gastro-intestinal membrane increasing their bio-availability. Therefore niaziridin can be used in combination therapy with drugs and nutrients resulting in reduced drug associated toxicity, reduced cost and duration of chemotherapy.Type: ApplicationFiled: March 31, 2003Publication date: October 7, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Suman Preet Singh Khanuja, Jai Shanker Arya, Ranganathan Santha Kumar Tiruppadiripuliyur, Dharmendra Saikia, Harpreet Kaur, Monika Singh, Subhash Chandra Gupta, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Santosh Kumar Srivastava, Madan Mohan Gupta, Subash Chandra Verma, Anirban Pal
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Publication number: 20040198815Abstract: The present invention relates to the new use of an already known biomolecule methyl-&bgr;-orcinol carboxylate of formula 1 isolated from a lichen (Everniastrum cirrhatum), for treating pathogenic fungal infections of humans that are resistant to polyene and azole antibiotics such as amphotericin B, nystatin, clotrimazole etc.Type: ApplicationFiled: March 31, 2003Publication date: October 7, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Suman Preet Singh Khanuja, Ranganathan Santha Kumar Tiruppadiripuliyur, Vivek Kumar Gupta, Preeti Chand, Ankur Garg, Santosh Kumar Srivastava, Subash Chandra Verma, Dharmendra Saikia, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Anirban Pal
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Publication number: 20040199969Abstract: This invention relates to a new distinct early maturing, high seed and husk yielding variety of psyllium (Plantago ovata) designated as var. ‘Mayuri’ with the distinct pigment marker of the panicles relatable to the maturity thereby indicating the right harvesting stage to prevent the seed shattering, a problem in psyllium. This variety was developed by mutation breeding (gamma rays irradiation) and propagated by seeds for commercial cultivation. The new variety could be differentiated from the other variety through unique RAPD profile and has been tested for uniformity and stability of characters defined. Psyllium plant ‘Mayuri’ with stage marker and early maturity.Type: ApplicationFiled: March 31, 2003Publication date: October 7, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Raj Kishori Lal, Nilakshi Singh, Hari Om Mishra, Jawahar Ram Sharma, Janak Raj Bahl, Ajit Kumar Shasany, Suman Preet Singh Khanuja
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Publication number: 20040191288Abstract: The present invention relates to an efficient process of vermicomposting and production of high-quality vermicompost from agro-waste(including distillation waste) using animal urine such as cattle urine.Type: ApplicationFiled: March 31, 2003Publication date: September 30, 2004Applicant: COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCHInventors: Suman Preet Singh Khanuja, Alok Kalra, Ranganathan Santha Kumar Tiruppadiripuliyur, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Dharni Dhar Patra, Virendra Kumar Singh Tomar, Om Parkash Dhawan, Rakesh Pandey, Ravi Prakash Bansal, Raj Kishori Lal, Govind Ram, Anirban Pal
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Publication number: 20040194176Abstract: The present invention was related to the development of a novel, distinct high yielding plant with rapid regeneration ability obtained through screening of the somaclones in a methodical way for fast regeneration in the tissue culture stage itself which was achieved by inventing the plant ‘Kushal’. The plant yield higher herbage with corresponding high essential oil when evaluated with available superior varieties of mint in late planting condition during April when the fields are vacated after the harvest of Rabi crop like wheat, chickpea, coriander etc. Further the suckers required for commercial vegetative planting can be produced even in low land condition as the plant is reasonably tolerant to water logging compared to the best check ‘Kosi’.Type: ApplicationFiled: March 31, 2003Publication date: September 30, 2004Inventors: Suman Preet Singh Khanuja, Ajit Kumar Shasany, Usha Yadav, Sunita Dhawan, Mahendra Pandurang Darokar, Janak Raj Bahl, Soni Gupta, Sweta Pandey, Anil Kumar Singh, Ravi Prakash Bansal, Raj Kishori Lal, Om Parkash Dhawan, Ali Arif Naqvi, Alok Kalra, Alok Krishna, Virendra Kumar Singh Tomar, Anil Kumar Singh
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Publication number: 20040194175Abstract: The present invention relates to a new and distinct high essential oil variety of lemon grass (Cymbopogon flexuosus) named as ‘Nima’. Further the invention relates to the high content of the monoterpene citral in the essential oil. This novel variety ‘Nima’ of the lemon grass is a selection from the open pollinated seedlings of the seeds obtained from another Cymbopogon flexuosus variety OD 19 from the germplasm collection of CIMAP. This variety is propagated through vegetative means using the slips and stable for commercial cultivation.Type: ApplicationFiled: March 31, 2003Publication date: September 30, 2004Inventors: Raj Kishori Lal, Hari Om Misra, Jawahar Ram Sharma, Nilakshi Singh, Ajit Kumar Shasany, Ali Arif Naqvi, Janak Raj Bahl, Arun Prasad, Suman Preet Singh Khanuja
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Patent number: 6767876Abstract: The present invention relates to disinfectant and cleansing compositions for cleaning the skin of humans and for cleaning surface such as floors, and the invention also provides process for the preparation of the said composition.Type: GrantFiled: March 10, 2003Date of Patent: July 27, 2004Assignees: Council of Scientific and Industrial Research, Department of BiotechnologyInventors: Suman Preet Singh Khanuja, Mahendra Pandurang Darokar, Tirupadiripuliyur Ranganathan Santhakumar, Ajit Kumar Shasany, Krishna Kumar Aggrawal, Atique Ahmed, Pushplata Chaturvedi, Vivek Kumar Gupta, Alok Krishna, Anil Kumar Singh, Janak Raj Bahl, Ravi Prakash Bansal, Dinesh Kumar
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Publication number: 20040029098Abstract: The present invention relates to a method of testing Bacopa monnieri response to abiotic stress factors and for testing bioactivity of natural, synthetic and semisynthetic compounds using Bacopa monnieri plant, which comprises growing the said plant and plant parts aseptically in MS 0 basal medium with agar in microcentrifuge tubes by adding the compounds to be tested either to the culture media or by spraying the said compounds on the plant or plant parts or on the said medium to detect the distinct morphological and cytological responses.Type: ApplicationFiled: December 13, 2002Publication date: February 12, 2004Applicant: Council of Scientific and Industrial ResearchInventors: Sushil Kumar, Suman Preet Singh Khanuja, Mahendra Pandurang Darokar, Tiruppadiripuliyur Ranganathan Santha Kumar, Anita Gangwar, Ajit Kumar Shasany, Srilekha Mishra, Shalini Mathur, Dharmendra Saikia
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Publication number: 20040014620Abstract: The present invention relates to disinfectant and cleansing compositions for cleaning the skin of humans and for cleaning surface such as floors, and the invention also provides process for the preparation of the said composition.Type: ApplicationFiled: March 10, 2003Publication date: January 22, 2004Applicants: COUNCIL OF SCIENTIFIC AND INDUSTRIAL, DEPARTMENT OF BIOTECHNOLOGY, A DEPARTMENT OF THE GOVERNMENT OF INDIAInventors: Suman Preet Singh Khanuja, Mahendra Pandurang Darokar, Tirupadiripuliyur Ranganathan Santhakumar, Ajit Kumar Shasany, Krishna Kumar Aggrawal, Atique Ahmed, Pushplata Chaturvedi, Vivek Kumar Gupta, Alok Krishna, Anil Kumar Singh, Janak Raj Bahl, Ravi Prakash Bansal, Dinesh Kumar
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Patent number: 6676974Abstract: The present invention relates a hexane bioactive fraction and obtained from the roots of an aromatic plant named Vetiveria zizanioides commonly found in India for inhibiting the growth of drug resistant bacterial infections in humans and animals; also relates to a pharmaceutical composition comprising the bioactive extract with other additives for inhibiting the growth of drug resistant bacterial infections in humans and animals and a process for the isolation of said bioactive extractType: GrantFiled: March 26, 2002Date of Patent: January 13, 2004Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Suchi Srivastava, Tiruppadiripuliyur Ranganathan Santha Kumar, Madan Mohan Gupta, Arvind Kumar Tripathy, Monika Singh, Janak Raj Bahl, Raj Kishori Lal, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Sushil Kumar
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Patent number: 6660761Abstract: The present invention relates to a method of treatment of fungal infections consisting essentially of a synergistic combination of plant compounds that are useful for enhancing the activity of antifungal compounds. The plant compounds, menthol and menthyl acetate, when mixed at specific concentrations, enhance the antifungal activity of the commercially available fungicides.Type: GrantFiled: February 6, 2002Date of Patent: December 9, 2003Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Puspalata Chatruvedi, Krishna Kumar Agarwal, Atique Ahmad, Tiruppadiripuliyur Ranganathan Santha Kumar, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Jai Shankar Arya, Sushil Kumar
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Publication number: 20030215901Abstract: The present invention describes a novel and very quick bacterial system based screening protocol to detect UV protectant molecules and determining their efficacy for the extent of protection against Ultraviolet radiation in biological systems, identifying a new use of the compound menthyl benzoate as efficient UV protectant suitable for providing protection against the harmful effects of ultraviolet radiation and the extent of protection provided by menthyl benzoate.Type: ApplicationFiled: June 17, 2003Publication date: November 20, 2003Applicant: Council of Scientific and Industrial Research Rafi MargInventors: Suman Preet Singh Khanuja, Krishna Kumar Agarwal, Tiruppadiripuliyur Ranganathan Santha Kumar, Atique Ahmad, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Sushil Kumar
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Publication number: 20030198698Abstract: The present invention relates a hexane bioactive fraction and obtained from the roots of an aromatic plant named Vetiveria zizanioides commonly found in India for inhibiting the growth of drug resistant bacterial infections in humans and animals; also relates to a pharmaceutical composition comprising the bioactive extract with other additives for inhibiting the growth of drug resistant bacterial infections in humans and animals and a process for the isolation of said bioactive extractType: ApplicationFiled: March 26, 2002Publication date: October 23, 2003Applicant: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Suchi Srivastava, Tiruppadiripuliyur Ranganathan Santha Kumar, Madan Mohan Gupta, Arvind Kumar Tripathy, Monika Singh, Janak Raj Bahl, Raj Kishori Lal, Mahendra Pandurang Darokar, Ajit Kumar Shasany, Sushil Kumar
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Patent number: PP14400Abstract: The invention relates to a new, distinct and unique plant of rose scented geranium Pelargonium graveolens ‘Safal’ derived from a rare seed-set in cultivar ‘Bipuli,’ apparently the result of hybridization between largely sterile populations of the cultivar accessions ‘Bipuli’ and ‘Hemanti’, possessing the following combination of characteristics namely demonstrated vigour in the essential oil yield related traits in great measure and out yielded all the other accessions; the essential oil of the plant has 89% rhodinol content in which citronellol to geraniol ratio is approximately 1:1 and the contents of isomenthone, menthone, 10-epi-&ggr;-eudesmol, 6,9-guaiadiene, decanoic acid and isodecanoic acid were relatively lower than in the oils of accessions ‘Bipuli’ and/or ‘Hemanti’, this plant can be propagated vegetatively through stem cuttings and suitable for commercial cultivation in large scale.Type: GrantFiled: March 7, 2001Date of Patent: December 23, 2003Assignee: Council of Scientific & Industrial ResearchInventors: Sushil Kumar, Ritika Gupta, Kakaraparthi Pandu Sastry, Suchitra Banerjee, Gopal Rao Mallavarapu, Srinivas Iyer Ramesh, Ajit Kumar Shasany, Mahendra Pandurang Darokar, Suman Preet Singh Khanuja
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Patent number: PP14538Abstract: The present invention relates to a novel, insect tolerant, high yielding essential oil and menthol yielding mint plant named ‘Sambhav’, which is a cultivar of Mentha arvensis L.. The mint plant of the present invention has been developed as a result of planned experiments which devised a procedure for early selection of somaclonal variants at the in vitro stage of the variety of Mentha arvensis.Type: GrantFiled: January 18, 2000Date of Patent: February 17, 2004Assignee: Council of Scientific and Industrial ResearchInventors: Suman Preet Singh Khanuja, Ajit Kumar Shasany, Sunita Dhawan, Mahendra Pandurang Darokar, Sarita Satapathy, Tiruppadiripuliyur Ranganathan Santha Kumar, Dharmendra Saikia, Nirmal Kumar Patra, Janak Raj Bahl, Arun Kumar Tripathy, Sushil Kumar