Patents by Inventor Akifumi Kato

Akifumi Kato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210107997
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Application
    Filed: December 22, 2020
    Publication date: April 15, 2021
    Applicants: RIKEN, KYOWA KIRIN CO., LTD.
    Inventors: Kensaku Sakamoto, Kazumasa Ohtake, Yoshimi Yamaguchi, Shigeyuki Yokoyama, Tatsuo Yanagisawa, Akiko Matsumoto, Akifumi Kato, Yasuhisa Shiraishi, Kaname Kimura, Masakazu Homma
  • Patent number: 10906990
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Grant
    Filed: August 18, 2016
    Date of Patent: February 2, 2021
    Assignees: RIKEN, KYOWA KIRIN CO., LTD.
    Inventors: Kensaku Sakamoto, Kazumasa Ohtake, Yoshimi Yamaguchi, Shigeyuki Yokoyama, Tatsuo Yanagisawa, Akiko Matsumoto, Akifumi Kato, Yasuhisa Shiraishi, Kaname Kimura, Masakazu Homma
  • Publication number: 20190127488
    Abstract: The present invention relates to a monoclonal antibody or antibody fragment thereof as a human IgG antibody including at least one lysine derivative in a constant region of the human IgG antibody; a modified antibody or antibody fragment thereof, wherein the lysine derivative is modified; a nucleic acid including a nucleotide sequence encoding the antibody or antibody fragment thereof; a vector including the nucleic acid; a transformed cell obtained by introducing the vector into a host cell; a method for producing the antibody or antibody fragment thereof; and a composition containing the antibody or antibody fragment thereof.
    Type: Application
    Filed: August 18, 2016
    Publication date: May 2, 2019
    Applicants: RIKEN, KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Kensaku SAKAMOTO, Kazumasa OHTAKE, Yoshimi YAMAGUCHI, Shigeyuki YOKOYAMA, Tatsuo YANAGISAWA, Akiko MATSUMOTO, Akifumi KATO, Yasuhisa SHIRAISHI, Kaname KIMURA, Masakazu HOMMA
  • Patent number: 9999898
    Abstract: There is provided an applicator that applies a coating liquid onto the upper surface of a web, and an application method which are capable of sufficiently enhancing the evenness of a coating surface. The applicator includes: a bar which rotates while coming into contact with the upper surface of the continuously travelling web via the coating liquid; and a barrier plate which is provided on an upstream side of the bar in a travelling direction of the web and allows the coating liquid to flow in a direction toward the web between the barrier plate and the bar, in which, when a distance between the barrier plate and an end edge portion of the bar, which is closest to the barrier plate, is referred to as A and a distance between the barrier plate and the web is referred to as B, A is 0.5 mm to 5 mm, B is 0.5 mm to 5 mm, and B?A is satisfied.
    Type: Grant
    Filed: March 3, 2016
    Date of Patent: June 19, 2018
    Assignee: FUJIFILM Corporation
    Inventors: Akifumi Kato, Takanori Sato, Manabu Hashigaya, Takahiro Sakamoto
  • Publication number: 20160175879
    Abstract: There is provided an applicator that applies a coating liquid onto the upper surface of a web, and an application method which are capable of sufficiently enhancing the evenness of a coating surface. The applicator includes: a bar which rotates while coming into contact with the upper surface of the continuously travelling web via the coating liquid; and a barrier plate which is provided on an upstream side of the bar in a travelling direction of the web and allows the coating liquid to flow in a direction toward the web between the barrier plate and the bar, in which, when a distance between the barrier plate and an end edge portion of the bar, which is closest to the barrier plate, is referred to as A and a distance between the barrier plate and the web is referred to as B, A is 0.5 mm to 5 mm, B is 0.5 mm to 5 mm, and is satisfied.
    Type: Application
    Filed: March 3, 2016
    Publication date: June 23, 2016
    Applicant: FUJIFILM Corporation
    Inventors: Akifumi KATO, Takanori SATO, Manabu HASHIGAYA, Takahiro SAKAMOTO
  • Patent number: 8501914
    Abstract: A pharmaceutical agent for treating a disease such as inflammatory diseases, blood coagulation diseases associated with deficiency of Protein S has been required. The present invention provides a Protein S composition comprising recombinant Protein S molecules having complex type N-glycoside-linked sugar chains, wherein the Protein S has a higher binding activity to a receptor for advanced glycation end products (hereinafter referred to as “RAGE”) than native Protein S present in healthy human blood, and also has a higher ratio of sugar chains in which fucose is not bound to the complex type N-glycoside-linked sugar chains bound to Protein S than native Protein S present in healthy human blood.
    Type: Grant
    Filed: August 13, 2009
    Date of Patent: August 6, 2013
    Assignee: Kyowa Hakko Kirin Co., Ltd
    Inventors: Yutaka Kanda, Hiroshi Sato, Tsuyoshi Yamada, Akifumi Kato, Mitsuo Satoh
  • Publication number: 20100162418
    Abstract: A pharmaceutical agent for treating a disease such as inflammatory diseases, blood coagulation diseases associated with deficiency of Protein S has been required. The present invention provides a Protein S composition comprising recombinant Protein S molecules having complex type N-glycoside-linked sugar chains, wherein the Protein S has a higher binding activity to a receptor for advanced glycation end products (hereinafter referred to as “RAGE”) than native Protein S present in healthy human blood, and also has a higher ratio of sugar chains in which fucose is not bound to the complex type N-glycoside-linked sugar chains bound to Protein S than native Protein S present in healthy human blood.
    Type: Application
    Filed: August 13, 2009
    Publication date: June 24, 2010
    Applicant: KYOWA HAKKO KIRIN CO., LTD.
    Inventors: Yutaka KANDA, Hiroshi SATO, Tsuyoshi YAMADA, Akifumi KATO, Mitsuo SATOH
  • Patent number: 7713729
    Abstract: A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.
    Type: Grant
    Filed: July 25, 2007
    Date of Patent: May 11, 2010
    Assignee: FUJIFILM Corporation
    Inventors: Kenji Nakajima, Akifumi Kato
  • Patent number: 7531057
    Abstract: A continuous substrate and a continuous absorptive sheet are fed to a press station, and pressed continuously or intermittently. Part of the continuous absorptive sheet is charged in plural holes formed in the continuous substrate to form a biochemical analysis sheet. The biochemical analysis sheet is cut into predetermined tips to obtain a biochemical analysis unit.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: May 12, 2009
    Assignee: FUJIFILM Corporation
    Inventors: Akifumi Kato, Kenji Nakajima
  • Publication number: 20090020922
    Abstract: A dope is cast onto a casting drum from a casting die while forming a casting bead. Oxygen concentration at the vicinity of the casting bead is set to 0 vol % or more and less than 10 vol %, and a static electricity applying electrode applies static electricity between the casting drum and the casting bead. An intervening film forming device supplies intervening film forming liquid onto the casting drum to form an intervening film. A compression chamber decompresses a downstream area from the casting bead. Thereby, it is possible to form the casting bead having a stable shape, and enhance the extent of adhesion between a casting film and the casting drum. Accordingly, it is possible to enhance the extent of adhesion between the casting drum and the casting bead, prevent occurrence phenomenon of air entrainment, and speed up a film forming speed, thus forming a polymer film.
    Type: Application
    Filed: February 27, 2007
    Publication date: January 22, 2009
    Applicant: FUJIFILM CORPORATION
    Inventors: Akifumi Kato, Hidekazu Yamazaki
  • Patent number: 7368026
    Abstract: In producing a biochemical analysis unit (1), an adhesive agent (25) is applied to a base. After calcinations, the adhesive agent (25) forms an adhesive layer (25a, 25b) on a wall of each holes (3) formed in the base (2). Thereafter, an excess adhesive agent (25c) remaining on the surface of the base (2) is removed. Then, a sheet of an absorptive material (4) is set to overlap the base (2). A press roller pair (27, 28) presses them to charge the absorptive material (4) in the holes (3). Thus the absorptive material (4) is fixed in the hole (3) of the base (2) through the adhesive layer (25a, 25b).
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: May 6, 2008
    Assignee: FUJIFILM Corporation
    Inventors: Kenji Nakajima, Akifumi Kato
  • Publication number: 20080054515
    Abstract: There is provided a casting drum having an outer peripheral surface provided with an electrical insulating layer. Direct-current high voltage is applied to an electrode bar disposed in an upstream side from a discharge port to discharge toward the casting drum. Bead is attracted to the charged casting drum by electrostatic attraction. Thereby, the adhesion between the bead and the casting drum is increased, and therefore the occurrence of phenomenon of air entrainment can be prevented. A wet film obtained by peeling a casting film from the casting drum is dried. Accordingly, it is possible to produce a film having few defects such as voids and high quality such as excellent smoothness at high speed and stably.
    Type: Application
    Filed: September 6, 2007
    Publication date: March 6, 2008
    Applicant: FUJIFILM Corporation
    Inventors: Akifumi Kato, Hidekazu Yamazaki, Hitoshi Ikeda
  • Publication number: 20080054514
    Abstract: A polymer film producing apparatus includes a casting device, having a casting die, for ejecting dope to form a bead, and casting the bead on a support drum traveling continuously to form a cast film, the dope containing polymer, solvent and additive. A dryer dries the cast film stripped from the support drum, to obtain a polymer film. A voltage application device is connected with the support drum, for applying voltage to the support drum during casting of the casting device. Preferably, the support drum is electrically non-grounded, and has a surface coated with an electrical insulation film. A surface potential V of the support drum is in a range of 0.1 kV<|V|<3 kV. A decompression chamber is disposed close to a surface of the support drum, for tightening contact of the bead on the surface of the support drum.
    Type: Application
    Filed: September 6, 2007
    Publication date: March 6, 2008
    Applicant: FUJIFILM CORPORATION
    Inventors: Akifumi KATO, Hidekazu YAMAZAKI, Hitoshi IKEDA
  • Publication number: 20070274859
    Abstract: A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.
    Type: Application
    Filed: July 25, 2007
    Publication date: November 29, 2007
    Inventors: Kenji Nakajima, Akifumi Kato
  • Patent number: 7262048
    Abstract: A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: August 28, 2007
    Assignee: Fujifilm Corporation
    Inventors: Kenji Nakajima, Akifumi Kato
  • Publication number: 20070184483
    Abstract: The biochemical analysis unit has a base plate and absorptive regions. The absorptive regions are surrounded by the base plate formed of materials which shield a radioactive ray and a light. In the absorptive regions are applied and absorbed specific binding substances to be bound with substances derived from a living organism that are labeled with labeling substances for generating the radioactive ray or the light. The base plate prevents the specific binding substances from penetrating in the other absorptive regions. When an analysis of data of the radioactive ray and the light is carried out, an image of the radioactive ray and the light is generated without noises.
    Type: Application
    Filed: April 6, 2007
    Publication date: August 9, 2007
    Inventors: Keiko Neriishi, Yuichi Hosoi, Katsuhiro Kohda, Masahiro Eto, Akifumi Kato, Kenji Nakajima
  • Patent number: 7220389
    Abstract: The biochemical analysis unit has a base plate and absorptive regions. The absorptive regions are surrounded by the base plate formed of materials which shield a radioactive ray and a light. In the absorptive regions are applied and absorbed specific binding substances to be bound with substances derived from a living organism that are labeled with labeling substances for generating the radioactive ray or the light. The base plate prevents the specific binding substances from penetrating in the other absorptive regions. When an analysis of data of the radioactive ray and the light is carried out, an image of the radioactive ray and the light is generated without noises.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: May 22, 2007
    Assignee: Fujifilm Corporation
    Inventors: Keiko Neriishi, Yuichi Hosoi, Katsuhiro Kohda, Masahiro Eto, Akifumi Kato, Kenji Nakajima
  • Publication number: 20070045896
    Abstract: A dope is produced from TAC and a mixture solvent whose main compound is dichloromethane. The dope is cast from a casting die onto a casting drum. In an upstream side from the casting die, a decompression chamber having air pipes is provided. The difference from the ordinate pressure to the pressure inside the decompression chamber is ?2000 Pa to ?10 Pa. An air is fed through the air pipes into the decompression chamber. Thus the pressure fluctuation in the decompression chamber is reduced, and the pressure becomes almost constant in the widthwise direction. Therefore, the entrained air and another air are prevented from entering into the decompression chamber, which makes the shape of the bead of the discharged casting dope stable. When having self-supporting properties, the casting film is peeled as a film from the casting drum and dried to be a TAC film without thickness unevenness.
    Type: Application
    Filed: August 31, 2006
    Publication date: March 1, 2007
    Inventors: Akifumi Kato, Hidekazu Yamazaki
  • Publication number: 20040185550
    Abstract: A biochemical analysis unit comprises a base plate, which has holes, and a porous adsorptive material, which is filled in each of the holes and forms each of adsorptive regions. Each of the adsorptive regions is provided with a layer, which has pores having a comparatively small mean pore diameter, and a layer, which has pores having a comparatively large mean pore diameter. In cases where the layers, which constitute each of the adsorptive regions, are connected with the layers, which constitute an adjacent adsorptive region, at one of surfaces of the base plate, the biochemical analysis unit further comprises a signal absorbing layer for absorbing a signal, which passes through layers located under the base plate and thus propagates from a certain hole toward an adjacent hole.
    Type: Application
    Filed: March 16, 2004
    Publication date: September 23, 2004
    Applicant: FUJI PHOTO FILM CO., LTD.
    Inventors: Kenji Nakajima, Akifumi Kato
  • Publication number: 20030153070
    Abstract: In producing a biochemical analysis unit (1), an adhesive agent (25) is applied to a base. After calcinations, the adhesive agent (25) forms an adhesive layer (25a, 25b) on a wall of each holes (3) formed in the base (2). Thereafter, an excess adhesive agent (25c) remaining on the surface of the base (2) is removed. Then, a sheet of an absorptive material (4) is set to overlap the base (2). A press roller pair (27, 28) presses them to charge the absorptive material (4) in the holes (3). Thus the absorptive material (4) is fixed in the hole (3) of the base (2) through the adhesive layer (25a, 25b).
    Type: Application
    Filed: January 31, 2003
    Publication date: August 14, 2003
    Applicant: Fuji Photo Film Co., Ltd.
    Inventors: Kenji Nakajima, Akifumi Kato