Abstract: The present invention provides a therapeutic and/or prophylactic medicament for FGFR3 diseases, the medicament comprising a HMG-CoA reductase inhibitor as an active ingredient; a method for treating and/or preventing FGFR3 diseases, the method comprising administering a HMG-CoA reductase inhibitor; use of a HMG-CoA reductase inhibitor in the production of a therapeutic and/or prophylactic medicament for FGFR3 diseases; and a method for screening for a therapeutic and/or prophylactic drug for FGFR3 diseases.

Abstract: A saddle type vehicle including a frame of a monocoque structure having an air cleaner wherein the sealing property can be secured. An air cleaner includes a filter element disposed in a hollow main frame to partition the main frame into a dirty side region and a clean side region. An intake path member connects an engine below the main frame to the clean side region. A communicating opening for communicating with the engine is formed on a lower face side of the clean side region. The communicating opening is covered with a lid member. The lid member includes a first plate member with a communicating hole in which the intake path member to the engine is inserted, a second plate member for surrounding an outer periphery of the first plate member, and an elastic member provided between the first plate member and the second plate member.

Abstract: An image processing unit includes a first memory unit configured to store a first setup value which is set for each of groups including a user and indicates an upper limit of a usage amount, within which the user included in each group can use a function; a second memory unit configured to store a second setup value which is set for each user and indicates the usage amount enabling each user to use the function in addition to the first setup value; a third memory unit configured to store a current value which indicates the usage amount of the function used by each user; and a determination unit configured to determine whether the current value exceeds a predetermined first threshold determined using the first setup value set for the group and the second setup value set for each user.

Abstract: A method for forming an undercut portion of a formed article formed by plastically deforming a plate-shaped workpiece and a method for manufacturing a formed article having an undercut portion are provided. In these methods, the undercut portion is formed by press working performed using a punch and a die. These methods make the forming work more economical and more efficient. An outer portion of a plate member 91 (plate-shaped workpiece) located outward of a portion where an inwardly inclined portion 94 (undercut portion) is to be formed is bent by an angle determined such that an undercut surface 94a which constitutes the inwardly inclined portion 94 becomes parallel to the pressing direction of a punch 110. In addition, a peripheral wall portion 93 inclined by an angle corresponding to the bending angle is formed on the outer portion.

Abstract: A saddle type vehicle including a frame of a monocoque structure having an air cleaner wherein the sealing property can be secured. An air cleaner includes a filter element disposed in a hollow main frame to partition the main frame into a dirty side region and a clean side region. An intake path member connects an engine below the main frame to the clean side region. A communicating opening for communicating with the engine is formed on a lower face side of the clean side region. The communicating opening is covered with a lid member. The lid member includes a first plate member with a communicating hole in which the intake path member to the engine is inserted, a second plate member for surrounding an outer periphery of the first plate member, and an elastic member provided between the first plate member and the second plate member.

Abstract: A saddle type vehicle wherein restrictions in the weight and the layout are reduced for slimmer and lighter vehicle. Pivot plates are provided as separate bodies from seat rails. An upper end of a shock absorber is received by a cross member located between left and right seat rails. The cross member is a separate body from the seat rails. Both ends of the cross member are supported by recesses provided in the left and right seat rails at inner sides of the seat rails so as to face each other. The cross member is fastened to the seat rails by cross member fastening members. The seat rail is attached to a main frame at its one front-side end and to the pivot plate at its other front-side end. The main frame and the seat rail are fastened to each other in the vertical direction by a first fastening member.

Abstract: A saddle type vehicle to improve the workability in fastening a frame and an engine together and thereby to enhance productivity. The saddle type vehicle includes a head pipe, a main frame extending rearwardly from the head pipe, and a seat rail located rearwardly of the main frame for supporting a seat. The main frame is fastened to the engine by fastening members being directed from an outer side toward an inner side in the vehicle widthwise direction. A knock pin is provided between the main frame and the engine, in a position in the vicinity of at least one of the fastening members.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A frame for a vehicle to accommodate a large-sized accessory, such as a fuel tank, to be mounted downwardly of a rear pipe without having to lower a rear sub-pipe. A large-sized accessory, such as a fuel tank, can be inserted into a space under a rear pipe by removing a second rear sub-pipe from a main frame and the rear pipe. The second rear sub-pipe can be fixed to the main frame and the rear pipe by simply tightening bolts. Similarly, by simply loosening the bolts the second rear sub-pipe can be removed from the main frame and the rear pipe and the large-sized accessory can be removed onto an outside in a vehicle width direction. This facilitates mounting and helps reduce the number of man-hours involved in mounting the accessory.

Abstract: A first communication apparatus 100 transmits a pilot signal which was generated by a pilot signal generation section 14, at predetermined timing, and detects an unbalance component of a transmission line 300 at the time of pilot signal transmission in an unbalance component detection section 13, and controls a transmission signal in such a manner that an unbalance component is reduced by a transmission control section 12 on the basis of the detected unbalance component.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A method for forming an undercut portion of a formed article formed by plastically deforming a plate-shaped workpiece and a method for manufacturing a formed article having an undercut portion are provided. In these methods, the undercut portion is formed by press working performed using a punch and a die. These methods make the forming work more economical and more efficient. An outer portion of a plate member 91 (plate-shaped workpiece) located outward of a portion where an inwardly inclined portion 94 (undercut portion) is to be formed is bent by an angle determined such that an undercut surface 94a which constitutes the inwardly inclined portion 94 becomes parallel to the pressing direction of a punch 110. In addition, a peripheral wall portion 93 inclined by an angle corresponding to the bending angle is formed on the outer portion.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A vehicle includes a vehicle body frame, an engine attached to the vehicle body frame, and a power transmission unit for transmitting output from the engine to a wheel of the vehicle. The vehicle body frame includes a plate-shaped suspension-supporting bracket which is integrally connected to front end portions of main frame sections extending in a forward/rearward direction of a vehicle at a lower portion of the vehicle body frame, and also is integrally connected to lower end sides of front frame sections vertically extending at a front portion of the vehicle body frame. The plate-shaped suspension-supporting bracket includes suspension arm-supporting portions formed integrally therewith. The lightweight vehicle body frame reduces total weight of the vehicle and, at the same time, enhances assembling accuracy thereof.

Abstract: The vehicle body frame is configured in a manner that an upper tension pipe is removed from a first cross portion and a second cross portion. When mounting the engine in the vehicle body frame, the vehicle mounted component that is relatively heavy can be lowered into the vehicle body frame from above by removing the upper tension pipe. The vehicle body frame simplifies the removal and installation of the vehicle-mounted components.

Abstract: A process of forming an ultrafine crystal layer in a workpiece constituted by a metallic material. The process includes: performing a machining operation on a surface of the workpiece, so as to impart a large local strain to the machined surface of the workpiece, where the machining operation causes the machined surface of the workpiece to be subjected to a plastic working that causes to have large local strain in the form of a true strain of at least one, such that the ultrafine crystal layer is formed in a surface layer portion of the workpiece that defines the machined surface of the workpiece. Also disclosed are a nanocrystal layer forming process, a machine component having the ultrafine crystal layer or the nanocrystal layer, and a machine component producing process of producing the machine component.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.

Abstract: A network-management device includes a map storing unit and a map state storing unit. The map storing unit stores therein a map created based on information on network devices. The map state storing unit stores therein a creation state indicating that creation of the map is in process or completed in association with the map. When creation of the map is in process, disclosure of the map is prohibited, and all the network devices are notified that creation of the map is in process. When creation of the map is completed, it is checked whether all the network devices are laid out on the map. When all the network devices are laid out on the map, disclosure of the map is permitted.