Patents by Inventor Akiko Iwasaki

Akiko Iwasaki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220256262
    Abstract: An OLT connected with a controller managing slices includes a bandwidth allocating unit capable of allocating bandwidths in a PON system to ONUs through allocation methods, a slice managing unit that calculates a guaranteed delay time for each allocation method, receives, from the controller, a resource reservation request including a bandwidth requested to be reserved in the PON system for a slice and a requested delay time, and determines an allocation method associated with the request based on the requested delay time and the guaranteed delay time for each allocation method, and a resource information generating unit that holds, as abstract resource information, an available bandwidth for the guaranteed delay times of each ONUs, calculates an available bandwidth in the allocation method of the associated ONU based on the allocation method associated with the request and the requested bandwidth, and updates and transmits the abstract resource information, to the controller.
    Type: Application
    Filed: April 26, 2022
    Publication date: August 11, 2022
    Applicant: Mitsubishi Electric Corporation
    Inventors: Takeshi SUEHIRO, Kenichi NAKURA, Akiko IWASAKI
  • Publication number: 20220231963
    Abstract: A controller that is a resource management device includes: a history information storage unit storing, for each combination of endpoint nodes constituting endpoints of a network and for each type of service, history information indicating used bands previously required for providing a service; a non-used resource calculation unit calculating non-used resource information based on the history information stored corresponding to a first service that is a service already allocated a resource, the non-used resource information indicating a resource that is not used while the first service is provided; and an available resource generation unit generating available resource information based on the non-used resource information, the available resource information indicating an available resource including a shareable resource and available to a second service to be newly provided, the shareable resource being a part, shareable with the second service, of the resource already allocated to the first service.
    Type: Application
    Filed: April 6, 2022
    Publication date: July 21, 2022
    Applicant: Mitsubishi Electric Corporation
    Inventors: Akiko IWASAKI, Kenichi NAKURA, Takeshi SUEHIRO, Seiji KOZAKI
  • Publication number: 20220226363
    Abstract: The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises at least one 5?-triphosphate and/or at least one 5?-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject.
    Type: Application
    Filed: March 30, 2022
    Publication date: July 21, 2022
    Inventors: Anna Marie Pyle, Akiko Iwasaki, Tianyang Mao
  • Publication number: 20220175810
    Abstract: The present disclosure provides small hairpin nucleic acid molecules capable of stimulating interferon production. The nucleic acid molecules of the present disclosure has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5?-triphosphate or a 5?-diphosphate. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection, and/or ameliorating, minimizing, reversing, and/or preventing persistent SARS-CoV-2 viral infection, and/or minimizing or preventing SARS-CoV-2 viral infection-derived mortality and/or lethality, in a subject. In certain embodiments, compounds and/or compositions of the disclosure are useful for treating, ameliorating, and/or preventing SARS-CoV-2 viral infection in a tumor-bearing subject.
    Type: Application
    Filed: December 28, 2021
    Publication date: June 9, 2022
    Inventors: Anna Marie Pyle, Akiko Iwasaki, Tianyang Mao
  • Publication number: 20220131610
    Abstract: A network control device for generating a slice by dividing a network and allocating communication resources to the slice, the slice being a virtual network, the network control device including: a processor; and a memory to store a program which, when executed by the processor, performs processes of: obtaining and holding resource information from a network device included in the network, the resource information including information on a maximum usage rate of communication resources allocated to a previously generated slice in at least one predetermined period; and determining, upon receiving a request for generating a new slice, whether or not the requested slice can be generated on the basis of the resource information held, wherein the resource information includes information on a maximum usage rate of communication resources, which are allocated to the previously generated slice, depending on a request delay concerning the slice in the predetermined period.
    Type: Application
    Filed: January 5, 2022
    Publication date: April 28, 2022
    Applicant: Mitsubishi Electric Corporation
    Inventors: Kenichi NAKURA, Takeshi SUEHIRO, Akiko IWASAKI, Jun MIZUGUCHI
  • Publication number: 20220008510
    Abstract: A method of inducing lymphangiogenesis in the brain or central nervous system of a subject is provided in which an effective amount of a lymphangiogenesis inducer is administered. A method of inducing lymphangiogenesis in a tumor in the brain or central nervous system of a subject is provided in which an effective amount of a lymphangiogenesis inducer is administered. A method of treating a cancer of the brain or central nervous system is also provided in which an effective amount of a lymphangiogenesis inducer is administered. An example of a lymphangiogenesis inducer is VEGFC. The lymphangiogenesis inducer can be in the form of a protein or a polynucleotide encoding the protein, such as an mRNA or AAV. The lymphangiogenesis inducer can be administered to the cistemamagna or directly into the lymphatic system. An immunotherapeutic agent, such as a checkpoint inhibitor, may also be administered.
    Type: Application
    Filed: November 15, 2019
    Publication date: January 13, 2022
    Applicant: Yale University
    Inventors: Akiko IWASAKI, Jean-Leon THOMAS, Eric SONG
  • Publication number: 20210401955
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of immunoprivileged tissue. It is described herein that an immunogenic composition which induces production of memory CD4 T cells allows for the access of a therapeutic antibody to the immunoprivileged tissue.
    Type: Application
    Filed: September 7, 2021
    Publication date: December 30, 2021
    Inventors: Norifumi Iijima, Akiko Iwasaki
  • Publication number: 20210409343
    Abstract: A network controller is configured to perform, to a new slice request, resource allocation from a resource of unallocated resource information managed by a resource information management unit, and to reallocate the resource to an existing slice request so that an unallocated resource increases based on unallocated resource information managed by the resource information management unit.
    Type: Application
    Filed: September 8, 2021
    Publication date: December 30, 2021
    Applicant: MITSUBISHI ELECTRIC CORPORATION
    Inventors: Takeshi SUEHIRO, Yukio HIRANO, Kenichi NAKURA, Akiko IWASAKI, Hiromu SATO
  • Patent number: 11147862
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of immunoprivileged tissue. It is described herein that an immunogenic composition which induces production of memory CD4 T cells allows for the access of a therapeutic antibody to the immunoprivileged tissue.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: October 19, 2021
    Assignee: Yale University
    Inventors: Norifumi Iijima, Akiko Iwasaki
  • Publication number: 20210260093
    Abstract: The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
    Type: Application
    Filed: June 20, 2019
    Publication date: August 26, 2021
    Inventors: Akiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova
  • Publication number: 20210102209
    Abstract: The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5?-triphosphate or a 5?-diphosphate.
    Type: Application
    Filed: December 9, 2020
    Publication date: April 8, 2021
    Inventors: Anna Marie Pyle, Andrew Kohlway, Dahai Luo, David Rawling, Akiko Iwasaki, Tianyang Mao
  • Patent number: 10947543
    Abstract: The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5? triphosphate or a 5? diphosphate.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: March 16, 2021
    Assignee: Yale University
    Inventors: Anna Marie Pyle, Andrew Kohlway, Dahai Luo, David Rawling, Akiko Iwasaki
  • Publication number: 20210054380
    Abstract: The present invention provides a small hairpin nucleic acid molecule that is capable of stimulating interferon production. The nucleic acid molecule of the present invention has a double-stranded section of less than 19 base pairs and at least one blunt end. In certain embodiments, the molecule comprises a 5? triphosphate or a 5? diphosphate.
    Type: Application
    Filed: August 25, 2020
    Publication date: February 25, 2021
    Inventors: Anna Marie Pyle, Andrew Kohlway, Dahai Luo, David Rawling, Akiko Iwasaki
  • Publication number: 20200061097
    Abstract: The present invention provides combination therapies that are useful for treating and/or preventing certain cancers. In certain embodiments, the therapy comprises an immune-checkpoint inhibitor and a RIG-I agonist. In other embodiments, the therapy comprises a RIG-I agonist.
    Type: Application
    Filed: September 3, 2019
    Publication date: February 27, 2020
    Inventors: Akiko Iwasaki, Anna Marie Pyle, Xiaodong Jiang, Olga Fedorova
  • Publication number: 20170326214
    Abstract: The present disclosure relates to compositions and methods for treating or preventing a disease or disorder of immunoprivileged tissue. It is described herein that an immunogenic composition which induces production of memory CD4 T cells allows for the access of a therapeutic antibody to the immunoprivileged tissue.
    Type: Application
    Filed: May 16, 2017
    Publication date: November 16, 2017
    Inventors: Norifumi Iijima, Akiko Iwasaki
  • Publication number: 20150147355
    Abstract: The present invention relates to a vaccination strategy that establishes protective immunity, including a protective memory T-cell population.
    Type: Application
    Filed: March 8, 2013
    Publication date: May 28, 2015
    Inventors: Akiko Iwasaki, Norifuma Iijima, Haina Shin
  • Patent number: 5446010
    Abstract: A thermosensitive recording material having a high thermosensitivity and useful for recording thereon colored images having high storage persistency, comprises a thermosensitive colored image-forming layer formed on a surface of a substrate sheet and comprising a colorless dye precursor; a color-developing aromatic compound having, per molecule thereof, at least one arylsulfonylureido group of the formula (I): ##STR1## wherein R.sup.1 =aromatic group unsubstituted or substituted with at least one of lower alkyl and lower alkoxyl group and hologen atoms; a sensitizing aromatic amide compound of the formula (II): ##STR2## wherein Ar.sup.1, Ar.sup.2 =non-substituted phenyl or naphthyl group or substituted phenyl or naphthyl group with 1 to 3 substituent selected from aryl, aryloxy, aralkyl, alkyl, alkoxyl, trihalogenomethyl, nitro and alkylamino groups and halogen atoms; and a binder.
    Type: Grant
    Filed: April 12, 1994
    Date of Patent: August 29, 1995
    Assignee: New Oji Paper Co., Ltd.
    Inventors: Kunitaka Toyofuku, Akiko Iwasaki
  • Patent number: 5444036
    Abstract: A thermosensitive recording material for recording thereon clear colored images having an excellent storage persistency over a long time, comprises a thermosensitive colored image-forming layer formed on a substrate and comprising a colorless dye precursor, a binder and a color developing agent comprising at least one compound having at least one group of the formula (I): ##STR1## wherein R = unsubstituted aromatic group or substituted aromatic group having at least one substituent selected from alkyl, alkoxyl and halogen, and the thermosensitive colored image-forming layer further comprises an additive comprising at least one member selected from the compounds of the formulae (II) and (III): ##STR2## wherein R.sup.1, R.sup.2, R.sup.3 = alkyl, alkoxyl, aralkyl, aryl, aryloxy, nitro, acetylamino, acetoacetylamino, halogen or hydrogen; and Ar.sub.1, Ar.sub.
    Type: Grant
    Filed: January 7, 1994
    Date of Patent: August 22, 1995
    Assignee: New Oil Paper Co., Ltd.
    Inventors: Akiko Iwasaki, Kunitaka Toyofuku, Kyoko Uchida, Masatoshi Fujino
  • Patent number: 5256618
    Abstract: A thermosensitive recording material capable of recording thereon colored images having high resistances to oily substances, plasticizers, moisture, and heat and an excellent storage persistency over a long time, comprises a thermosensitive colored image-forming layer formed on a sheet substrate and comprising a colorless dye precursor, a color developing agent, and a binder, the color developing agent comprising at least one compound of the formula (I): ##STR1## wherein X is an O or S atom, R is an unsubstituted aromatic group or an aromatic group substituted by a lower alkyl or halogen atom; A represents a multivalent group, and n is an integer of 2 or more.
    Type: Grant
    Filed: October 2, 1992
    Date of Patent: October 26, 1993
    Assignee: Oji Paper Co., Ltd.
    Inventors: Yoshiyuki Takahashi, Akiko Iwasaki, Kunitaka Toyofuku
  • Patent number: 5246906
    Abstract: A thermosensitive recording material capable of recording thereon colored images having high resistances to oily substances, plasticizers, moisture, and heat and an excellent storage persistency over a long time, comprises a thermosensitive colored image-forming layer formed on a sheet substrate and comprising a colorless dye precursor, a color developing agent, and a binder, the color developing agent comprising at least one compound of the formula (I): ##STR1## wherein X is an O or S atom, R.sup.1 is an unsaturated aromatic group or a substituted phenyl group having a lower alkyl or halogen atom and R.sup.2 and R.sup.3 are respectively a hydrogen atom, alkyl, aralkyl, substituted alkyl having an aryloxy, unsubstituted aromatic group, or substituted aromatic group having at least one substituent selected from alkyl, aryl, aralkyl, alkyloxy, alkyloxycarbonyl, aryloxycarbonyl, aralkyloxycarbonyl, and arylsulfonyl groups, and halogen atoms.
    Type: Grant
    Filed: July 17, 1992
    Date of Patent: September 21, 1993
    Assignee: Oji Paper Co., Ltd.
    Inventors: Yoshiyuki Takahashi, Akiko Iwasaki, Kunitaka Toyofuku