Abstract: In an embodiment, an object of the present invention is to provide a double-stranded nucleic acid complex having a novel structure. In an embodiment, the present invention relates to a nucleic acid complex comprising a first nucleic acid strand and a second nucleic acid strand, wherein said first nucleic acid strand: (1) is capable of hybridizing to at least a part of a target transcriptional product; (2) has an antisense effect on the target transcriptional product; and (3) is a gapmer comprising a central region, and a 5? wing region and a 3? wing region, said second nucleic acid strand comprises at least one sugar-unmodified central region (first exposed region) consisting of one sugar-unmodified ribonucleoside or two or three contiguous sugar-unmodified ribonucleosides linked by an internucleoside bond, which is or are complementary to a part of said first nucleic acid strand, and said first nucleic acid strand is annealed to said second nucleic acid strand.

Abstract: A clearer image is acquired while redundancy of analysis time is suppressed. A biological sample analysis system according to an embodiment includes: an irradiation unit (101) that irradiates a bioparticle in a biological sample with light; a detection unit (102) including a plurality of pixels that each detects, as an event, a luminance change of light emitted from the bioparticle by irradiation with the light; and a processing unit (103) that generates bioparticle information regarding the bioparticle on the basis of the event detected by each of the pixels.

Abstract: According to some aspects, a medical imaging system is provided. The medical imaging system includes an illumination device and a medical imaging device. The illumination device includes a first light source configured to emit first light having a wavelength range. The illumination device further includes a second light source configured to emit second light having at least one predetermined wavelength band. The at least one predetermined wavelength band is within the wavelength range. The illumination device further includes a dichroic mirror configured to attenuate a portion of the wavelength range corresponding to the at least one predetermined wavelength band and to multiplex the second light with the first light such that the portion of the wavelength range of the first light is attenuated. The light multiplexed by the dichroic mirror is emitted from the illumination device along an optical axis and irradiates an observation site.

Abstract: To improve visual recognition of a medical practitioner on information displayed on a screen under a shadowless lamp. There is provided an information processing device including: an information acquisition unit that acquires information from an information providing device that provides the information related to quantitative numerical values to be grasped by a medical practitioner involved with a medical practice; an image data generation unit that generates image data related to the acquired information; and a control unit that controls an installation position of a light source irradiating drawing light having illuminance visually recognizable under a shadowless lamp or an operation state of an optical system that scans an irradiation position of the drawing light so as to draw the image data.

Abstract: There is provided an information processing device including an information acquisition unit that acquires information from an information providing device that provides the information related to quantitative numerical values to be grasped by the medical practitioner involved with a medical practice, an image data generation unit that generates image data related to the acquired information, and a control unit that controls an installation position of a light source irradiating drawing light having illuminance visually recognizable under a shadowless lamp or an operation state of an optical system that scans an irradiation position of the drawing light so as to draw the image data.

Abstract: The present technology relates to an image processing device, an image processing method, an endoscope system, and a program that enable motion detection with higher accuracy. The endoscope system includes: a light source capable of performing a pulsed-light emission; a light-source control unit that controls the light source such that the light source performs the pulsed-light emission a plurality of times in an exposure time period of each captured image; an imaging unit that takes the captured images; and a motion detection unit that detects a motion of a photographic subject in the captured images. The present technology is applicable to the endoscope system.

Abstract: To enable calculation a wavelength shift amount more accurately. A light source system is provided including a light source unit configured to emit a light beam, and a calculation unit configured to calculate a wavelength shift amount of the light beam on the basis of an output from a color sensor that detects the light beam.

Abstract: [Object] To provide a light source device and imaging system capable of issuing a warning to a user in accordance with an actual deterioration state of a light source. [Solution] The light source device includes: at least one light source; a light monitor unit that detects emitted light emitted from the light source; a light source drive unit that controls a drive current or an applied voltage of the light source such that a detection value detected by the light monitor unit indicates a predetermined target value; and a warning unit that performs a primary warning when the drive current or the applied voltage of the light source reaches a predetermined reference value, and performs a predetermined process on a basis of a deterioration level of the light source after the primary warning is performed.

Abstract: The present technology relates to an image processing device, an image processing method, an endoscope system, and a program that enable motion detection with higher accuracy. The endoscope system includes: a light source capable of performing a pulsed-light emission; a light-source control unit that controls the light source such that the light source performs the pulsed-light emission a plurality of times in an exposure time period of each captured image; an imaging unit that takes the captured images; and a motion detection unit that detects a motion of a photographic subject in the captured images. The present technology is applicable to the endoscope system.

Abstract: To provide an illumination device, a control device, and a control method enabled to perform control to cause output of each of a plurality of light sources to be constant with a more simplified temperature control circuit. There is provided an illumination device including: a plurality of light sources; a plurality of cooling units respectively provided for the light sources and respectively cooling the light sources; and a drive control unit that performs switching of control with respect to each of the light sources on the basis of a comparison between a target temperature of each of the light sources and a measured temperature of each of the light sources or an environment.

Abstract: According to some aspects, a medical imaging system is provided. The medical imaging system includes an illumination device and a medical imaging device. The illumination device includes a first light source configured to emit first light having a wavelength range. The illumination device further includes a second light source configured to emit second light having at least one predetermined wavelength band. The at least one predetermined wavelength band is within the wavelength range. The illumination device further includes a dichroic mirror configured to attenuate a portion of the wavelength range corresponding to the at least one predetermined wavelength band and to multiplex the second light with the first light such that the portion of the wavelength range of the first light is attenuated. The light multiplexed by the dichroic mirror is emitted from the illumination device along an optical axis and irradiates an observation site.

Abstract: To enable calculation a wavelength shift amount more accurately. A light source system is provided including a light source unit configured to emit a light beam, and a calculation unit configured to calculate a wavelength shift amount of the light beam on the basis of an output from a color sensor that detects the light beam.

Abstract: According to some aspects, a medical imaging system is provided. The medical imaging system includes an illumination device and a medical imaging device. The illumination device includes a first light source configured to emit first light having a wavelength range. The illumination device further includes a second light source configured to emit second light having at least one predetermined wavelength band. The at least one predetermined wavelength band is within the wavelength range. The illumination device further includes a dichroic mirror configured to attenuate a portion of the wavelength range corresponding to the at least one predetermined wavelength band and to multiplex the second light with the first light such that the portion of the wavelength range of the first light is attenuated. The light multiplexed by the dichroic mirror is emitted from the illumination device along an optical axis and irradiates an observation site.

Abstract: Provided is a medical light source device that includes a light source part including two or more semiconductor light-emitting devices having wavelengths of emitted light different from each other. The light source part generates light of predetermined chromaticity by mixing the light emitted from each of the semiconductor light-emitting devices and emits outward the generated light of the chromaticity as illumination light. The medical light source device further includes a control unit that controls a mixing rate of the light emitted from each of the semiconductor light-emitting devices based on a light amount setting value of the illumination light emitted from the light source part, and keeps the chromaticity constant regardless of a light amount of the illumination light.

Abstract: It is enabled to more appropriately prevent thermal damage to an area irradiated with illumination light. An image acquisition system is provided including: a first light source unit that emits narrow band light having a peak intensity in a specific band; a second light source unit that emits wide band light having a band wider than the specific band; a generation unit that generates multiplexed light by using the narrow band light and the wide band light; an imaging unit that images an irradiation target of the multiplexed light; a prediction unit that performs prediction of a temperature of an area irradiated with the multiplexed light in the irradiation target; and a control unit that performs control of outputs of the narrow band light and the wide band light on the basis of the prediction.

Abstract: An illumination apparatus includes an optical apparatus configured to optically process laser light to produce illumination light such that speckle noise in the illumination light is reduced. The optical apparatus includes at least one collimator (130) configured to collimate the laser light and a diffuser (140) configured to diffuse the laser light.

Abstract: An illuminating device includes an image acquisition system configured to adjust a plurality of light sources on the basis of a correlation between luminance acquired from an image processing device and the light amounts of the emission light beams. Accordingly, the color temperature of the image processing device can be accurately adjusted because the illuminating device can control the plurality of light sources by individual adjustment to output a desired light.

Abstract: To more easily inhibit a change in chromaticity that occurs at the time of light amount fluctuation of semiconductor light-emitting devices without providing a feedback system. A medical light source device according to the present disclosure includes: a light source part including two or more semiconductor light-emitting devices having wavelengths of emitted light different from each other, the light source part being configured to generate light of predetermined chromaticity by mixing the light emitted from each of the semiconductor light-emitting devices and emitting outward the generated light of the chromaticity as illumination light; and a control unit configured to control a mixing rate of the light emitted from each of the semiconductor light-emitting devices in accordance with a light amount setting value of the illumination light emitted from the light source part, the control unit being configured to keep the chromaticity constant regardless of a light amount of the illumination light.

Abstract: [Object] To propose a control apparatus, a control system and a control method which are capable of causing another light source to adaptively emit light at a timing at which light emitted from one light source changes. [Solution] A control apparatus including: a light source control unit configured to control light emission of a second light source on the basis of profile of light emitted from a first light source and a synchronization signal for synchronizing a timing between the first light source and the second light source for radiating light on a surgical region.

Abstract: It is enabled to more appropriately prevent thermal damage to an area irradiated with illumination light. An image acquisition system is provided including: a first light source unit that emits narrow band light having a peak intensity in a specific band; a second light source unit that emits wide band light having a band wider than the specific band; a generation unit that generates multiplexed light by using the narrow band light and the wide band light; an imaging unit that images an irradiation target of the multiplexed light; a prediction unit that performs prediction of a temperature of an area irradiated with the multiplexed light in the irradiation target; and a control unit that performs control of outputs of the narrow band light and the wide band light on the basis of the prediction.