Abstract: In a polypropylene resin/silicone rubber integrally molded article, a polypropylene resin having an aliphatic unsaturated bond is integrally joined to an addition type silicone rubber at high bond strength. It is prepared by injection molding a modified polypropylene resin into a preform, injection molding a silicone rubber composition over the preform, and curing the composition at a temperature below the softening point of the polypropylene resin. Stronger bond is established when the silicone rubber contains a tackifier in the form of a compound containing in a molecule at least one hydrogen atom directly attached to a silicon atom and an alkoxysilyl, glycidyl or acid anhydride group or a --(CH.sub.2).sub.n -- linkage.

Abstract: An adhesive silicone rubber composition of addition reaction curing type comprising (a) an organopolysiloxane containing an alkenyl group; (b) an organohydrogenpolysiloxane having at least one hydrogen atom directly attached to a silicon atom in a molecule; (c) an addition reaction catalyst; and (d) an adhesive agent selected from compounds of the following formulae (I), (II) and (III):A-(D-B).sub.x -D-A (I)C-(B-D).sub.

Abstract: 2'-Methylidenepyrimidine nucleoside compounds of the general formula: ##STR1## wherein R.sup.1 stands for amino or hydroxy group; R.sup.2 stands for a halogen or a lower alkyl when R.sup.1 is amino or R.sup.2 stands for an alkyl having 2 to 4 carbon atoms, an alkynyl having 2 to 4 carbon atoms or a haloalkyl when R.sup.1 is hydroxy group; and R.sup.3 stands for hydrogen or a phosphoric acid residue, or salts thereof, compositions containing one or more of these compounds and methods for production of these compounds are disclosed.Said compounds and salts thereof exhibit noticeable antitumor activities.

Abstract: In a polycarbonate resin/silicone rubber integrally molded article, a polycarbonate resin having an aliphatic unsaturated group, typically an isopropenyl group is integrally joined to an addition type silicone rubber containing a tackifier component at high bond strength. It is prepared by injection molding a modified polycarbonate resin into a preform, injection molding a silicone rubber composition over the preform, and curing the composition at a temperature below the softening point of the polycarbonate resin.

Abstract: An electric contact material containing Li oxide of 0.01 to 2.0% by weight when represented in terms of the amount of Li, oxide of at least one rare earth element of 0.05 to 0.18% by weight when represented in terms of the amount of the rare earth element, and Ag or Ag alloy as the remaining portion; an electric contact material containing Li oxide of 0.01 to 2.0% by weight when represented in terms of the amount of Li, at least one rare earth element of 0.05 to 0.18% by weight when represented in terms of the amount of the rare earth element, at least one element selected from a group consisting of In, Sn, Zn, Mn, Pd, Sb, Cu, Mg, Pb, Cd, Cr and Bi by an amount of 0.1 to 1.0% by weight (however, in the case of Zn and Mn, the amount is set less than 0.5% by weight), and/or at least one element selected from a group consisting of Fe, Ni and Co by an amount of 0.03 to 0.6% by weight, and Ag as the remaining portion; and an electric contact formed by using the above material.

Abstract: A method of chucking semiconductor wafers, in which a silicone elastic layer with high flatness is formed on the surface of a hard substrate having fine through-holes for vacuum chucking. Next fine through-holes in the silicone elastic layer, are provided, each through-hole communicating with the fine through-holes of the hard substrate. Next a semi-conductor wafer is held on the hard substrate by vacuum chucking from the back side of the substrate, so as to hold the semiconductor wafer securely on the substrate only by surface adhesion of the silicone elastic layer during polishing of the wafer. This method does not require wax or similar adhesive for holding the semiconductor wafer on the hard surface during the polishing process, and can realize a high-precision and high-quality surface polishing process for the semiconductor wafers.

Abstract: The present invention relates to a processing method of wire material and a processing device therefor at the times of intending to make the tip of wire materials such as guide wire for catheter thin and flexible by tapering.When the wire material passes through the electrolytic tub, the wire speed is made constant and the current value is controlled, or the current value is made constant and the wire speed is controlled to give the processings such as tapering. For the electrolytic polishing bath, it is desirable to use a mixed bath comprising trivalent alcohol, perchloric acid and monovalent alcohol.The inventive method exerts an effect that the tapering can be given efficiently and yet with high precision compared with the traditional method of mechanical polishing or the method of dipping one by one batchwise into the electrolytic polishing bath.

Abstract: Disclosed are novel 2'-alkylidenepyrimidine nucleoside derivatives represented by formula [I]: ##STR1## wherein R.sup.1 is an amino group or a hydroxy group, R.sup.2 is a hydrogen atom, a halogen atom or a lower alkyl group, R.sup.3 is a hydrogen atom or a lower alkyl group, and R.sup.4 is a hydrogen atom or a phosphate residue, or salts thereof.These novel compounds can be produced from uridine or cytidine derivatives by alkylidenating the 2'-position in the sugar moiety thereof with Wittig's reagent.Furthermore, the compounds have remarkable antiviral activities and therefore can provide novel antiviral agents.

Abstract: The present invention relates to a novel compound represented by the following formula [I] which is useful as a synthetic intermediate of a 2-alkynyladenosine.The present invention also relates to a process for producing the compound and a process for producing a 2-alkynyladenosine [IV] by way of the compound.Further, the present invention relates to a 2-alkynyladenosine derivative represented by the following formula [V] having excellent storage stability and, to a method of storing the 2-alkynyladenosine in the form of that derivative. ##STR1## wherein R.sup.1 through R.sup.4 represent a hydrogen atom or a protective group, and n denotes an integer of 1 to 15, provided that R.sup.1 through R.sup.4 do not represent a hydrogen atom simultaneously.

Abstract: Disclosed is a heat-resistant rubber composition comprising (A) 100 parts by weight of an ethylene/.alpha.-olefin copolymer or a modified ethylene/.alpha.-olefin copolymer formed by graft-copolymerization with at least one compound selected from the group consisting of unsaturated carboxylic acids and anhydrides and esters thereof, and (B) (i) 10 to 100 parts by weight of a silica type filler which has been treated with a silane compound represented by the following formula: ##STR1## wherein R.sup.1 stands for an alkenyl group, a chloroalkenyl group or a chloroalkyl group, and R.sup.2 stands for a lower alkyl group, or (ii) a combination of 10 to 100 parts by weight of said silane-treated silica type filler or an untreated silica type filler and 0.5 to 30 parts by weight of a polyorganosiloxane having an average composition represented by the following formula:(R.sup.3).sub.a (R.sup.4).sub.b SiO.sub.(4-a-b)/2 (II)wherein R.sup.3 stands for a monovalent saturated or unsaturated hydrocarbon group, R.sup.

Abstract: An improvement is proposed in the assemblage of a cover-packing bult-up body for a magnetic hard-disc unit to be freed from the troubles caused by dusts or contamination of the gap space between the magnetic recording disc and the magnetic head as well as by the poor vibration-damping characteristics of the rubber packing between the covering member and the body of the casing. The improvement comprises, instead of using a pre-shaped rubber packing, the built-up body is assembled by using a curable liquid silicone rubber-based composition filled with fine hollow microspheres to form a packing on the surface of the covering member by the in situ curing of the composition applied thereto so that the rubbery packing layer has a spongy structure exhibiting good vibration-damping characteristics.

Abstract: Disclosed herein are a novel 2-substituted adenosine derivative having the following formula [I] ##STR1## wherein R represents a hydrogen atom or a hydroxyl group, m is an integer of 2 to 7, n is 0 or an integer of 1 to 3, and R.sup.1, R.sup.2 and R.sup.3, which may be the same or different, each independently represent a hydrogen atom, a hydroxy protective group or a phosphoric acid residue, and salts thereof.The above compounds are excellent in a circulation ameliorating effect such as a vasodepressor activity, and have high selectivity for A.sub.2 receptors, but cause less undesirable side effects such as a suppresssive effect on the heart. They are therefore effective when used in pharmaceutical compositions for circulatory diseases.

Abstract: An electric contact material comprising 0.01 to 2.0 weight % of Li, 0.01 weight % or more to less than 0.2 weight % of at least one rare earth metal and the remainder being Ag. The electric contact material may further comprise 0.1 to 1.0 weight % of at least one element selected from a group consisting of In, Sn, Zn, Mn, Pd, Sb, Cu, Mg, Pb, Cd, Cr and Bi, however, for Zn and Mn, the amount is less than 0.5 % by weight; and/or 0.03 to 0.6 weight % of at least one element selected from a group consisting of Fe, Ni and Co. The electric contact material is excellent in arc resistance, wear resistance and lubricity in a small current region and is suitable as a material for a slide contact and a rotary slide contact.

Abstract: Disclosed is a thermoplastic elastomer composition excellent in the injection fusion bondability and the surface gloss, which comprises (1) an amorphous ethylene/.alpha.-olefin copolymer (a) and (2) (i) a lowly crystalline copolymer (b) of propylene with an .alpha.-olefin having at least 4 carbon atoms, (ii) a polymer (d) composed mainly of 1-butene or (iii) a combination of the copolymer (b) or the polymer (d) with a crystalline polymer (c) composed mainly of propylene, wherein the component (l) is present in an amount of 10 to 95% by weight based on the total amount of the components (1) and (2), the component (2) is present in an amount of 5 to 90% by weight based on the total amount of the components (1) and (2), and the component (1) or the components (1) and (2) are partially crosslinked.The partial crosslinking is effected by grafting of a radical-polymerizable monomer having at least two polymerizable groups.

Abstract: Disclosed are imidazole derivatives represented by formula [I]: ##STR1## wherein R is a hydrogen atom or ##STR2## wherein R.sup.2 is a hydrogen atom or a hydroxy protecting group, R.sup.2 protecting either a single hydroxy or two hydroxies together when R.sup.2 is a hydroxy protecting group, and R.sup.3 is a hydrogen atom or OR.sup.2 ; A is CONH.sub.2 or CN; and R.sup.1 is a hydrogen atom, lower alkyl, hydroxy lower alkyl, or phenyl.Also disclosed are six processes for producing these novel compounds among which a typical process comprises reacting a starting imidazole compound having a halogen at the 5-position thereof with an acetylene derivative to alkynylate the 5-position.Furthermore, the compounds have remarkable antitumor activities and therefore can provide novel antitumor agents.

Abstract: An optical fiber cable free from a generation of a microbent during manufacturing, and in which an impregnation of hydrogen and/or water to a cladding is prevented, and having high electrical conduction, tolerance to heat and mechanical strength, and a process for making same. The optical fiber cable includes a silica based glass optical fiber including a core and a cladding, a thin carbon coating formed on an outer surface of the optical fiber, and an electrically conductive coating formed on an outer surface of the carbon coating. The carbon coating functions as a layer for preventing the impregnation of hydrogen and/or water to the optical fiber, and the conductive coating functions as a heat tolerance member, a conductive member, and a mechanical support member. The carbon coating is preferably formed as an amorphous carbon layer.

Abstract: Disclosed are imidazole derivatives represented by formula [I]: ##STR1## wherein R is a hydrogen atom or ##STR2## wherein R.sup.2 is a hydrogen atom or a hydroxy protecting group, R.sup.2 protecting either a single hydroxy or two hydroxies together when R.sup.2 is a hydroxy protecting group, and R.sup.3 is a hydrogen atom or OR.sup.2 ; A is CONH.sub.2 or CN; and R.sup.1 is a hydrogen atom, lower alkyl, hydroxy lower alkyl, or phenyl.Also disclosed are six processes for producing these novel compounds among which a typical process comprises reacting a starting imidazole compound having a halogen at the 5-position thereof with an acetylene derivative to alkynylate the 5-position.Furthermore, the compounds having remarkable antitumor activities and therefore can provide novel antitumor agents.

Abstract: Disclosed are novel 2'-alkylidenepyrimidine nucleoside derivatives represented by formula [I]: ##STR1## wherein R.sup.1 is an amino gorup or a hydroxy group, R.sup.2 is a hydrogen atom, a halogen atom or a lower alkyl group, R.sup.3 is a hydrogen atom or a lower alkyl group, and R.sup.4 is a hydrogen atom or a phosphate residue, or salts thereof.These novel compounds can be produced from uridine or cytidine derivatives by alkylidenating the 2'-position in the sugar moiety thereof with Wittig's reagent.Furthermore, the compounds have remarkable antiviral activities and therefore can provide novel antiviral agents.

Abstract: Pyrimidine 2'-deoxy-2'-methylidene nucleoside compounds: ##STR1## wherein R.sup.1 represents amino, hydroxy, silylamino, silyloxy, acylamino or acyloxy; R.sup.2 represents hydrogen, halogen, a lower alkyl, a lower alkenyl, a lower alkynyl or haloalkyl; R.sup.3 and R.sup.4 represent the same or different hydrogen, silyl, acyl or aminoacyl, or a pharmaceutically acceptable salt or hydrate thereof, except that R.sup.1 is amino or hydroxy, and both of R.sup.3 and R.sup.4 are hydrogen.Said compounds possess excellent antitumor and antiviral activities, thus providing novel anticancer and antiviral agent.

Abstract: A 2-alkynyladenosine represented by general formula [I]: ##STR1## wherein n is an integer of from 2 to 15, has been found to have excellent properties as an antihypertensive agent. On the basis of this finding, the present invention has provided an antihypertensive agent comprising an antihypertensive effective amount of a compound of the above formula [I] and a pharmaceutically acceptable carrier. The present invention also discloses a novel compound 2-alkynyladenosine of formula [I] shown above wherein n is 6 to 15.